Impaired expression of glutathione peroxidase-4 gene in peripheral blood mononuclear cells: A biomarker of increased breast cancer risk

2010 ◽  
Vol 7 (1) ◽  
pp. 39-46 ◽  
Author(s):  
G. Bermano ◽  
E. Smyth ◽  
M. Goua ◽  
S.D. Heys ◽  
K.W.J. Wahle
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Glutathione Peroxidase ◽  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Mononuclear Cells ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells

scholarly journals Analysis of circulating breast cancer cell heterogeneity and interactions with peripheral blood mononuclear cells

2020 ◽  
Vol 59 (10) ◽  
pp. 1129-1139 ◽  
Author(s):  
Heather M. Brechbuhl ◽  
Kiran Vinod‐Paul ◽  
Austin E. Gillen ◽  
Etana G. Kopin ◽  
Kari Gibney ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Mononuclear Cells ◽  
Cell Heterogeneity ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells

scholarly journals In Vitro Cytotoxic Effect of 2-(Morpholin-4-Yl)-4,5-Bis(2’’,2’’,2’’-Trinitroethoxy)-1,3,5-Triazine on Human Fibroblasts, Peripheral Blood Mononuclear Cells and Breast Cancer Cells

2021 ◽  
Author(s):  
Larisa Limareva ◽  
Pavel Iliasov ◽  
Alexander Gidaspov ◽  
Vladimir Zalomlenkov ◽  
Aleksey Sustretov ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Breast Cancer Cells ◽  
Mononuclear Cells ◽  
Human Fibroblasts ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells

2-(Morpholin-4-yl)-4,5-bis(2’’,2’’,2’’-trinitroethoxy)-1,3,5-triazine having QSAR-predicted anti-tumor activity was tested for the cytotoxicity using MTT and LDH cell viability tests. The experiments were conducted using human fibroblasts, peripheral blood mononuclear cells and breast cancer cells and allowed to identify effective cytotoxic concentration ant therapeutic range of this compound. The data obtained suggest the feasibility of the further studies of the test compound as a potential anti-cancer agent.

Sign in / Sign up

Export Citation Format

Share Document