scholarly journals Integrated Bioinformatics Approach Reveals Crosstalk Between Tumor Stroma and Peripheral Blood Mononuclear Cells in Breast Cancer

2016 ◽  
Vol 17 (3) ◽  
pp. 1003-1008 ◽  
Author(s):  
Lang He ◽  
Dan Wang ◽  
Na Wei ◽  
Zheng Guo
2020 ◽  
Vol 59 (10) ◽  
pp. 1129-1139 ◽  
Author(s):  
Heather M. Brechbuhl ◽  
Kiran Vinod‐Paul ◽  
Austin E. Gillen ◽  
Etana G. Kopin ◽  
Kari Gibney ◽  
...  

Author(s):  
Larisa Limareva ◽  
Pavel Iliasov ◽  
Alexander Gidaspov ◽  
Vladimir Zalomlenkov ◽  
Aleksey Sustretov ◽  
...  

2-(Morpholin-4-yl)-4,5-bis(2’’,2’’,2’’-trinitroethoxy)-1,3,5-triazine having QSAR-predicted anti-tumor activity was tested for the cytotoxicity using MTT and LDH cell viability tests. The experiments were conducted using human fibroblasts, peripheral blood mononuclear cells and breast cancer cells and allowed to identify effective cytotoxic concentration ant therapeutic range of this compound. The data obtained suggest the feasibility of the further studies of the test compound as a potential anti-cancer agent.


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