Portuguese Higher Education Institutions have more and more data that needs to be processed in order to get information and, therefore, Knowledge. In order to respond to this need, over time there have been several types of IS supported by ICT, which enables them to achieve these features and, at the same time, help with their daily activities. However, the continuous evolution of this technological component has led to a current high degree of complexity, from which the Information Systems Architectures emerged as means of increasing the effectiveness of its management and maintenance. Using the University of Trás-os-Montes e Alto Douro as a case study, the research team proposed a generic ISA that enabled it to have a transversal vision of its IS, allowing the validation of existence/need IS focused on Information Management and decision-making under a multidimensional perspective, i.e., geared towards the various organizational levels, since the Operational level to the Strategic level, taking into account the information needs associated with each player.