Nutritional assessment in patients with Parkinson’s disease: The nutri-park study

BACKGROUND: Several studies have found a link between nutritional status and neurodegenerative diseases, such as Parkinson’s disease (PD). OBJECTIVE: The aim of our study was to assess both nutritional status and dietary habits of PD patients with respect to controls and to compare disease progression in relation to dietary habits, such as protein distribution diet (PRD) adherence. METHODS: We collected anthropometric measurements, Mini Nutritional Assessment (MNA) score, dietary habits, micro- and macronutrients intakes, body composition by Bioelectrical Impedance Analysis (BIA), muscle strength and gait speed of 66 PD patients and 58 controls (40 healthy controls and 18 subjects with essential tremor). Clinical scales and progression indexes were recorded in PD group. RESULTS: No significant differences emerged between PD and controls in anthropometric and BIA measurements; a comparable dietary intake between the two groups was recorded. Sarcopenia and dynapenia were comparable between the two groups. PD resulted more at risk of malnutrition than controls to MNA, only three patients and one control were malnourished. A notable inverse correlation was observed between MNA and PD Questionnaire 8. PD following a PRD showed a slower progression index. CONCLUSION: Nutritional status of PD patients is not so different from elderly controls. PRD is recommended for patients with PD.

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Reliability of Bioelectrical Impedance Analysis in the Evaluation of the Nutritional Status of Hemodialysis Patients — A Comparison With Mini Nutritional Assessment

Transplantation Proceedings ◽

10.1016/j.transproceed.2013.08.096 ◽

2013 ◽

Vol 45 (10) ◽

pp. 3485-3488 ◽

Cited By ~ 7

Author(s):

E. Erdoğan ◽

E. Tutal ◽

M.E. Uyar ◽

Z. Bal ◽

B.G. Demirci ◽

...

Keyword(s):

Nutritional Status ◽

Bioelectrical Impedance Analysis ◽

Nutritional Assessment ◽

Mini Nutritional Assessment ◽

Bioelectrical Impedance ◽

Impedance Analysis ◽

Hemodialysis Patients

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Nutritional Status Associated with Molecular Biomarkers, Physiological Indices, and Clinical Severity in Parkinson’s Disease Patients

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17165727 ◽

2020 ◽

Vol 17 (16) ◽

pp. 5727

Author(s):

Tsu-Kung Lin ◽

Yung-Yee Chang ◽

Nai-Ching Chen ◽

Chia-Wei Liou ◽

Min-Yu Lan ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Nutritional Status ◽

Rating Scale ◽

Nutritional Assessment ◽

Mini Nutritional Assessment ◽

Density Lipoprotein ◽

Molecular Biomarkers ◽

Clinical Severity ◽

Related Factors

This study is intended to explore the associations between nutritional status and molecular biomarkers and the clinical severity of Parkinson’s disease (PD), as well as to examine the differences in related factors between PD patients with normal nutrition and those with at risk for malnutrition. A cross-sectional assessment of 82 consecutive outpatients with PD was conducted using the mini nutritional assessment (MNA), Unified Parkinson’s Disease Rating Scale (UPDRS), and the Hoehn and Yahr scale to determine the nutritional status, the clinical severity of PD, and the stage of the disease. Recordings of blood samples collected after 12 h of overnight fasting were also assessed in terms of serum levels of glycated hemoglobin (HbA1c), blood urea nitrogen (BUN), creatinine, cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), hemoglobin (Hgb), folate, and vitamin B12. All participants were divided into normal nutrition and malnutrition risk groups via the MNA scores to compare the above-mentioned parameters. The results showed that the total MNA score was significantly correlated with some parts of the UPDRS scale (e.g., Sections 1 and 2) and the levels of HbAlc in PD patients and those with risk for malnutrition, with significantly lower weight and body mass index (BMI), and with lower levels of Hgb and HDL. Higher levels of cholesterol were observed in the malnutrition risk group as compared with the normal nutrition group. The findings suggest that the clinical severity of PD is associated with nutritional status. Body weight, BMI, and the levels of Hgb, cholesterol, and HDL could be, at least partially, important biological markers to monitor malnutrition and the progression of the disease.

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Denture Wearing and Malnutrition Risk Among Community-Dwelling Older Adults

Nutrients ◽

10.3390/nu12010151 ◽

2020 ◽

Vol 12 (1) ◽

pp. 151 ◽

Cited By ~ 2

Author(s):

Ya Su ◽

Michiko Yuki ◽

Kengo Hirayama ◽

Miho Sato ◽

Tianfang Han

Keyword(s):

Older Adults ◽

Nutritional Status ◽

Nutritional Assessment ◽

Short Form ◽

Mini Nutritional Assessment ◽

Bioelectrical Impedance ◽

Impedance Analysis ◽

The Elderly ◽

Community Dwelling ◽

Partial Denture

Most studies have associated denture wearing with a higher risk of malnutrition and lower nutritional intake in the elderly. As the effect of wearing dentures remains debatable, the aim of this study was to determine if older adults wearing dentures have a higher risk of malnutrition. We recruited 294 Japanese community-dwelling adults aged ≥65 years from two elderly welfare centers in Sapporo. The Mini Nutritional Assessment-Short Form (MNA-SF) was used to assess their nutritional status. Their demographic characteristics, eating habits, and health status were assessed using a questionnaire. Moreover, salt-impregnated taste paper and bioelectrical impedance analysis were used to obtain salt taste sensitivity and body composition (body mass index and protein mass). The mean age of older adults was 75.8 ± 5.8 years and 71.1% were women. We found that 74.1% of the older adults wore dentures. The proportion of the whole population with a risk of malnutrition was 23.5%. Multivariate analysis revealed that partial denture wearing could be protective against the risk of malnutrition. In this study, we found more partial denture wearers with normal nutritional conditions and cooking by themselves than non-denture-wearing older adults. Furthermore, complete denture wearers were eating significantly less meats or fish every day. This study suggests that using partial dentures to replace the lost teeth to meet the dietary needs of the elderly is critical to maintaining a healthy nutritional status. Moreover, it also indicates the importance of providing education to older adults who wear complete dentures.

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Effects of Polypharmacy on Appetite and Malnutrition Risk Among Institutionalized Lebanese Older Adults - Preliminary Results

Current Developments in Nutrition ◽

10.1093/cdn/nzaa040_069 ◽

2020 ◽

Vol 4 (Supplement_2) ◽

pp. 69-69

Author(s):

Berna Rahi ◽

Tracy Daou ◽

Nour Gereige ◽

Yara Issa ◽

Yara Moawad ◽

...

Keyword(s):

Older Adults ◽

Nursing Homes ◽

Nutritional Status ◽

Dietary Habits ◽

Nutritional Assessment ◽

Short Form ◽

Significant Risk ◽

Nursing Home Residents ◽

Mini Nutritional Assessment ◽

Significant Difference

Abstract Objectives We aimed to assess the polypharmacy effect on appetite and malnutrition risk among Lebanese nursing home residents. We hypothesized that polypharmacy will be associated to lower appetite and increased of malnutrition. Methods A cross-sectional pilot study was carried out in two nursing homes in the North-Lebanon region. Fifty-three older adults (OA) aged 60 and above were recruited and were interviewed face-to-face. A general questionnaire was administered to gather information about their socio-demographics, dietary habits and physical activity routine. Appetite was evaluated by the Simplified Nutritional Appetite Questionnaire (SNAQ) validated for use with nursing homes residents. The participants' nutritional status was assessed using the Short Form of the Mini-Nutritional Assessment (MNA-SF). Polypharmacy was determined if OA were taking 5 or more medications. Information about attitudes towards the use, the number and the cost of medications was also collected. Differences in SNAQ and MNA scores based on polypharmacy were tested using Independent t-tests. Logistic regression was performed to assess the association between polypharmacy and nutritional status after adjusting for several factors. Results Our sample constituted of 49.1% females with an average age of 67.6 ± 3.8 and BMI of 22.3 ± 1.7 kg/m2. The majority were widowed (79.2%) and had a low level of education (85% elementary education). Regarding the MNA scores, 33% had a normal nutritional status while 59% were at risk of malnutrition and 8% were malnourished, with an average MNA score of 10.1 ± 2.2. The average SNAQ score was 11.0 ± 3.3, with 85% scoring ≤14, indicating an significant risk of at least 5% weight loss withing 6 months. Regarding medication use, 50.9% of OA take at least 5 drugs/d with an average of 4.3 ± 2 drugs. Independent t-tests showed that MNA scores were significantly lower in those taking 5 drugs/d vs those taking less (9.4 ± 2.5 vs 10.8 ± 1.6, P = .024) while no significant difference was observed for SNAQ scores (10.3 ± 2.9 vs 11.6 ± 3.6, P = .13). Logistic regressions did not show any significant association between polypharmacy and MNA or SNAQ categories. Conclusions Lower MNA scores were observed in OA taking ≥5 drugs/d indicating a higher risk of malnutrition with polypharmacy. This is significant since malnutrition can further worsen the aging process. Funding Sources N/A.

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