scholarly journals Improving Clinical dosimetric Accuracy of cancer treatment using a special quality of Electron and Photon Beam

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Ayesha Ikhlaq ◽  
Saeed Ahmad Buzdar ◽  
Muhammad Usman Mustafa ◽  
Sana Salahuddin ◽  
Mehr-Un-Nisa ◽  
...  

In external beam radiation therapy, electron and photon beams have extraordinary characteristics in the treatment of cancer. The electron and photon beam characteristic are essential to study before calibration of machine. This study focused on the dosimetric characteristics of different energies of electron beams for different field size. The basic objective of this work is, to calculate dosimetric parameters and characteristics of electron beam, specially depth dose characteristics along central axis. In this work, 6 MeV, 9 MeV, 12 MeV, 15 MeV and 18 MeV of electron beam and 6 MV and 15 MV of photon beam with different field size is used. Characteristics of depth dose of electron and photon beam in water have analyzed to provide better quality of radiation therapy treatment planning. The different beam characteristics are due to different interactions that occurs between electron beams giving them a definite range whereas photon beams are attenuated leading to dose deposition and much larger range with no definite end. Depth dose characteristics of electron and photon beams do not show same characteristics as interaction of beam with matter depends on the quality of beam. Attenuation and penetration factors change with changing dosimetric parameters. Complete analysis of dosimetric characteristics of electron and photon beam help to choose more accurate beam for the treatment of cancer. This work will help to increase accuracy in treatment of cancer with radiotherapy.

2018 ◽  
Vol 18 (03) ◽  
pp. 280-284 ◽  
Author(s):  
Mohamed Bencheikh ◽  
Abdelmajid Maghnouj ◽  
Jaouad Tajmouati

AbstractAimThe purpose of this study is to introduce a new approach to assess the dosimetry quality of photon beam with energy and irradiation field size. This approach is based on percentage depth dose (PDD) fragmentation for investigating the dosimetry quality.Materials and methodsFor the investigation of the dosimetry quality of 6 and 18 MV photon beams, we have proceeded to fragment the PDD at different field sizes. This approach checks the overall PDD and is not restricted to the exponential decay regions, as per the International Atomic Energy Agency Technical Reports Series No 398 and the American Association of Physicist in Medicine Task Group 51 recommendations.Results and discussionThe 6 MV photon beam deposited more energy in the target volume than the 18 MV photon beam. The dose delivered by the 6 MV beam is greater by a factor of 1·5 than that delivered by the 18 MV beam in the build-up region and the dose delivered by the 6 MV beam is greater by a factor of 2·6 than that delivered by the 18 MV beam in the electronic equilibrium and the exponential decay regions.ConclusionThe dose measured at different points of the beam is higher for 6 MV than for 18 MV photon beam. Therefore, the 6 MV beam is more dosimetrically efficient than the 18 MV beam. Using the proposed approach, we can assess the dosimetry quality by taking into account overall PDD not only in the exponential decay region but also in the field.


2022 ◽  
Vol 12 (2) ◽  
pp. 600
Author(s):  
Serenella Russo ◽  
Silvia Bettarini ◽  
Barbara Grilli Leonulli ◽  
Marco Esposito ◽  
Paolo Alpi ◽  
...  

High-energy small electron beams, generated by linear accelerators, are used for radiotherapy of localized superficial tumours. The aim of the present study is to assess the dosimetric performance under small radiation therapy electron beams of the novel PTW microSilicon detector compared to other available dosimeters. Relative dose measurements of circular fields with 20, 30, 40, and 50 mm aperture diameters were performed for electron beams generated by an Elekta Synergy linac, with energy between 4 and 12 MeV. Percentage depth dose, transverse profiles, and output factors, normalized to the 10 × 10 cm2 reference field, were measured. All dosimetric data were collected in a PTW MP3 motorized water phantom, at SSD of 100 cm, by using the novel PTW microSilicon detector. The PTW diode E and the PTW microDiamond were also used in all beam apertures for benchmarking. Data for the biggest field size were also measured by the PTW Advanced Markus ionization chamber. Measurements performed by the microSilicon are in good agreement with the reference values for all the tubular applicators and beam energies within the stated uncertainties. This confirms the reliability of the microSilicon detector for relative dosimetry of small radiation therapy electron beams collimated by circular applicators.


2021 ◽  
Vol 27 (1) ◽  
pp. 25-29
Author(s):  
Labinot Kastrati ◽  
Gezim Hodolli ◽  
Sehad Kadiri ◽  
Elvin Demirel ◽  
Lutfi Istrefi ◽  
...  

Abstract Introduction: The aim of this study is to analyze the gradient of percentage depth dose for photon and electron beams of LINACs and to simplify the data set. Materials and Methods: Dosimetry measurements were performed in accordance with Technical Reports Series No. 398 IAEA. Results and discussion: The gradient of percentage depth dose was calculated and compared with the available published data. Conclusion: Instead of percentage depth dose for increasing and decreasing parts, the findings suggest using only two numbers for specific gradient of dose, separately. In this way, they can replace the whole set of the percentage depth dose (PDD).


2021 ◽  
Vol 229 ◽  
pp. 01041
Author(s):  
Kamal Saidi ◽  
Redouane El Baydaoui ◽  
Hanae El Gouach ◽  
Othmane Kaanouch ◽  
Mohamed Reda Mesradi

TrueBeam STx latest generation linear accelerators (linacs) installed at Sheikh Khalifa International University Hospital in Casablanca, Morocco. The aim of this is to present and compare the result of the Electron commissioning measurement on TrueBeam Stx and clinac iX installed at Sheikh Khalifa International University Hospital in Casablanca, Morocco. A compariaon of eMC calculations and measurements for TrueBeam Stx were evaluated. Dosimetric parameters are systematically measured using a large water phantom 3D scanning system MP3 Water Phantom (PTW, Freiburg, Germany). The data of the electron beams commissioning including depth dose curves for each applicator, depth dose curves without applicator and the profile in air for a large field size 40x 40cm2, and the Absolute Dose (cGy/MU) for each applicator. All the data were examined and compared for five electron beams (E6MeV, E9MeV, E12MeV, E16MeV and E20MeV) of Varian’s TrueBeam STx and Clinac iX machines. A comparison, between measurement PDDs and calculated by the Eclipse electron Monte Carlo (eMC) algorithm were performed to validate Truebeam Stx commissioning. All this measurements were performed with a Roos and Markus plane parallel chamber. Our measured data indicated that electron beam PDDs from the TrueBeam Stx machine are well matched to those from our Varian Clinac iX machine. Significant differences between TrueBeam and Clinac iX were found in in‐air profiles and open field output. Maximum depth dose for the TrueBeam Stx and Clinac iX for the following energies (6, 9, 12, 16, 20 MeV) are respectively (1.15; 1.89; 2.6; 3.1; and 2.35) and (1.24; 1.95; 2.70; 2.99 and 2.4cm). For the TrueBeam Stx and Clinac iX the quality index R50 for applicator 15x15 cm2 are in the tolerance intervals. Surface dose increases by increasing energy for both machines. The Absolute Dose (cGy/MU) calibrated for both machine in Dmax at 1cGy/MU for the reference field size cone 15x15 cm2. Bremsstrahlung tail Rp per energy levels as follows for the TrueBeam Stx : 6 MeV – 2.85 cm, 9 MeV – 4.28 cm, 12 MeV – 5.97 cm, 16 MeV – 7.88 cm and 20 MeV – 9.86 cm. and for the Clinac iX : 6 MeV – 2.86 cm, 9 MeV – 4.32 cm, 12 MeV – 5.96 cm, 16 MeV – 7.93 cm and 20 MeV – 10.08 cm. A good agreement between modeled and measured data is observed.


2016 ◽  
Vol 15 (4) ◽  
pp. 392-401
Author(s):  
Ankit kajaria ◽  
Neeraj Sharma ◽  
Shiru Sharma ◽  
Satyajit Pradhan ◽  
Abhijit Mandal ◽  
...  

AbstractPurposeIn our study basic dosimetric properties of a flattening filter free 6 MV photon beam shaped by multileaf collimators (MLC) is examined using the Monte Carlo (MC) method.Methods and MaterialsBEAMnrc code was used to make a MC simulation model for 6 MV photon beam based on Varian Clinic 600 unique performance linac, operated with and without a flattening filter in beam line. Dosimetric features including central axis depth dose, beam profiles, photon and electron spectra were calculated and compared for flattened and unflattened cases.ResultsDosimetric field size and penumbra were found to be smaller for unflattened beam, and the decrease in field size was less for MLC shaped in comparison with jaw-shaped unflattened beam. Increase in dose rate of >2·4 times was observed for unflattened beam indicating a shorter beam delivery time for treatment. MLC leakage was found to decrease significantly when the flattening filter was removed from the beam line. The total scatter factor showed slower deviation with field sizes for unflattened beam indicating a reduced head scatter.ConclusionsOur study demonstrated that improved accelerator characteristics can be achieved by removing flattening filter from beam line.


2021 ◽  
Vol 9 (B) ◽  
pp. 1730-1738
Author(s):  
Kamal Saidi ◽  
Othmane Kaanouch ◽  
Hanae El Gouach ◽  
Mohamed Reda Mesradi ◽  
Mounir Mkimel ◽  
...  

Electron beam measurement comparison between TrueBeam STx® and Clinac iX® established. Data evaluation of eMC-calculated and measured for TrueBeam STx® performed. Dosimetric parameters measured including depth dose curves for each applicator, percentage depth dose (PDDs) curves without applicator, the profile in-air for a large field size 40×40 cm2, and the Absolute Dose (cGy/MU) for each applicator using a large water phantom (PTW, Freiburg, Germany), employing Roos and Markus plane-parallel ionization chambers. The data were examined for five electron beams of Varian’s TrueBeam STx® and Clinac iX® machines. A comparison between measurement PDDs and calculated by the Eclipse electron Monte Carlo (eMC) algorithm was performed to validate Truebeam STx® commissioning. The measured data indicated that electron beam PDDs from the TrueBeam STx® machine are well matched to those from Clinac iX® machine. The quality index R50 for applicator 15×15 cm2 was in the tolerance intervals. However, Surface dose (Ds) increases with increasing energy for both accelerators. Comparisons between the measured and eMC-calculated values revealed that the R100, R90, R80, and R50 values mostly agree within 5 mm. Measured and calculated bremsstrahlung tail Rp correlates well statistically. Ds agrees mostly within 2%. Electron beams were successfully validated for TrueBeam STx®, a good agreement between modeled and measured data was observed.


We focus on the comparative study of dosimetry protocols in radiotherapy for accelerated photon and electron delivered from medical linear accelerator (LINAC). In this study, a comparison between the protocols (TRS 398, DIN 6800-2 and TG 51) for both the electron and photon delivered from Clinac 2300CD and Clinac DHX 3186 were performed. We used photon beams with energies of 6 and 15 MV and electron beams of 4, 6, 9, 12, 15 and 18 MeV for both Medical Linac. In case of Clinac the maximum deviations for the relative dose at Dmax for the photon beam (15 MV) among the protocols was observed to be 1.18% between TRS-398 and TG-51, 1.56% between TG-51 and DIN 6800-2; and 0.41% between TRS-398 and DIN 6800-2. Conversely, these deviations were 3.67% between TRS-398 and TG-51, 3.92% between TG-51 and DIN 6800-2 for 4 MeV and 0.95% between TRS-398 and DIN 6800-2 in the case of Clinac 2300 CD for the PTW Markus and Exradin A10. For the measurement of the maximum absorbed dose depth to water using three protocols, the maximum deviations were observed between TRS 398 and TG-51 as well as TG51 and DIN 6800-2.


Author(s):  
Elham Hoseinnezhad ◽  
Ghazale Geraily ◽  
Mahbod Esfahani ◽  
Mostafa Farzin ◽  
Somayeh Gholami

Abstract Purpose: Total body irradiation (TBI) is an external beam radiation therapy in which large field size and extended source skin distances (SSDs) are applied to deliver a therapeutic dose to the whole body. As measurements in such situations are not common and have more uncertainties in comparison to standard dosimetry situations, it is more precise if calculated beam data can be used instead of measurements taken under TBI situations. The purpose of this study is to compare calculated beam data [percentage depth dose (PDD) and dose rate] with those obtained from simulated treatment measurements. Materials and methods: PDD and dose rates were measured for the 6- and 18-MV photon beams under TBI and standard conditions using 9,000 cm3 water phantom and ion chambers (Markus and Farmer). The results were then compared with the calculated PDD and dose rate data. The beam flatness was also measured under TBI and standard conditions for both 6- and 18-MV photon beams, and the results were then compared. Results: A comparison of the measurement and calculated beam data shows that the difference between calculated and measured PDD values is −6·97 and −4·14% for the 6- and 18-MV photon beams, respectively. The ratio of calculated to measured dose rate was 1·09 and 1·02 for the 6- and 18-MV photon beams, respectively. The beam flatness under TBI conditions was 4·59% for 6-MV and 5·37% for 18-MV photon beam, whereas under standard conditions, these values were 1·50 and 1·98% for 6- and 18-MV radiation beams, respectively. Findings: According to the results, due to a high error level in dose rate and PDD calculations, these parameters must be directly measured under TBI conditions; however, regarding the obtained results, direct measurement is not necessary for the 18-MV photon beam.


Author(s):  
Serenella Russo ◽  
Silvia Bettarini ◽  
Barbara Grilli Leonulli ◽  
Marco Esposito ◽  
Paolo Alpi ◽  
...  

High-energy small electron beams generated by linear accelerators are used for radiotherapy of localized superficial tumors. The aim of the present study is to assess the dosimetric performance under small radiation therapy electron beams of the novel PTW microSilicon detector by comparison with commercially available dosimeters. Relative dose measurements of circular fields with 20, 30, 40 and 50 mm aperture diameters were performed for 4 to 12 MeV energy range of electron beams generated by an Elekta Synergy linac. Percentage depth dose, transverse profiles and output factors normalized to the 10 × 10 cm2 reference field were measured. All dosimetric data were collected in a PTW MP3 motorized water phantom at SSD of 100cm by using the novel PTW microSilicon detector. The PTW diode E and the PTW microDiamond were also used in all beam aperture for benchmarking. Data for the biggest field size were also measured by the PTW Advanced Markus ionization chamber.Measurements performed by the microSilicon are in good agreement with the reference values for all the tubular applicators and beam energies, within the stated uncertainties. This confirms the reliability of the microSilicon detector for relative dosimetry of small radiation therapy electron beams collimated by tubular applicators.


Author(s):  
Motiur Rahman ◽  
M Shamsuzzaman ◽  
Manoshi Sarker ◽  
Abdul Jobber ◽  
Mohsin Mia ◽  
...  

In radiotherapy treatment planning process, quality assessment (QA) is indispensable for achieving accuracy and avoidance of treatment errors. In this perspective, present study focused on the Photon and Electron beams characterization of a medical linear accelerator (LINAC) to ascertain dosimetric QA in Absolute and Reference dosimetry. In this connection, the beam outputs were investigated in terms of Dmax and Dw,max (dose at depth dmax) in absolute dosimetry for Photon and Electron beams, respectively. In accordance with the measured Dmax and Dw,max parameters, Photon and Electron beam outputs were standardized to ensure standard output of 1 cGy/MU. In reference dosimetry, the parametric evaluation was performed for dosimetric QA in terms of percent depth dose (PDD), beam profile flatness and symmetry, output factors: Scp, Sc, Sp with varying field size (FS) ranging from 4´4 cm2 to 40´40 cm2 normalized at FS 10´10 cm2 for the 6 MV and 10 MV Photon beams. The measured PDDs at 10 cm depth (D10) were found to be 66.8% and 73.6% for 6 MV and 10 MV Photon beams, respectively, with significantly small deviation of 1% and 0.8% in comparison with an international PDD protocol of British Journal of Radiology-25 (BJR -25). In the case of Electron beams characterization, PDD was verified with 10´10 cm2 cone/applicator, beam profile flatness and symmetry were analyzed at the field sizes ranging from 6´6 cm2 to 25´25 cm2 normalized at 10´10 cm2 cone/applicator, and Electron cone ratios were investigated for a given cone/applicator relative to the 15´15 cm2 one for the 6, 9, 12, 15 MeV Electron energies. The PDDs of all the Electron beams revealed reasonable consistency with manufacturer’s estimations of 90%, 80%, and 50% PDDs at various depths of ionization.


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