scholarly journals Intravascular Lymphoma of the Inferior Turbinate: An Unusual Rhinologic Presentation of a Rare Neoplasm

2007 ◽  
Vol 22 (1-2) ◽  
pp. 24-26 ◽  
Author(s):  
Milabelle B. Lingan ◽  
Francis V. Roasa

Objective: To present a unique case of intravascular lymphoma of the inferior turbinate because of its rarity, unusual clinical presentation and difficulty in establishing a diagnosis. Design:      Case Report Setting:      A tertiary hospital Patient:      A 66-year-old male admitted to the hospital due to intermittent high grade fever of six months duration. Result:  The patient presented with fever of unknown origin, and exhaustive laboratory, ancillary procedures and biopsies to rule in/out infectious, autoimmune and oncologic causes were performed to arrive at a diagnosis. Nasal endoscopy revealed an enlarged, hypertrophied and violaceous right inferior turbinate with watery to mucoid discharge and septal deviation to the right confirmed by CT scans of the paranasal sinuses. Functional Endoscopic Sinus Surgery (FESS), septoplasty and turbinoplasty with biopsy revealed Intravascular Lymphoma. Chemotherapy was deferred due to the deteriorating medical condition and the patient expired 7 months after the initial onset of symptoms. Conclusion:  Patients who present with fever of unknown origin should undergo a thorough otorhinolaryngologic examination to exclude primary ENT conditions and ensure proper management. Given its rarity and multiplicity of presentation, it is extremely difficult to make a diagnosis of intravascular lymphoma. A high index of suspicion of Intravascular Lymphoma is necessary so that timely acquisition of tissue biopsy of any lesion involved will make a definite diagnosis. Keywords: Intravascular lymphoma, Fever, Fever of Unknown Origin

2008 ◽  
Vol 136 (5-6) ◽  
pp. 292-294
Author(s):  
Radoje Colovic ◽  
Nikica Grubor ◽  
Vladimir Radak

INTRODUCTION Pyogenic gas containing liver abscesses are rare. Less than 50 cases seem to have been described so far. Most of them were localised within the right liver. The majority of those abscesses appear in diabetic patients. CASE OUTLINE The authors present a 64-year old diabetic male patient in whom the investigation (US, CT, plain X-ray) performed for fever of unknown origin confirmed a giant liver gas containing abscess that destroyed almost the entire left liver. Escherichia coli sensitive to several antibiotics was isolated from the abscess. The patient was cured by surgical drainage, limited debridement, lavage, drainage and antibiotics. CONCLUSION Pyogenic gas containing liver abscesses are easy to diagnose nowadays. The type of surgical drainage has to be adapted to a particular patient.


2004 ◽  
Vol 45 (8) ◽  
pp. 1691-1693 ◽  
Author(s):  
Aliza Zeidman ◽  
Alon Horowitz ◽  
Zinaida Fradin ◽  
Amos Cohen ◽  
Lea Wolfson ◽  
...  

2019 ◽  
Author(s):  
Hai-Yan Ye ◽  
Fan-Fan Xing ◽  
Jin Yang ◽  
Simon K.F Lo ◽  
Ricky W.T. Lau ◽  
...  

Abstract Background:Brucellosis is one of the most widespread zoonosis worldwide, it is caused by Gram-negative coccobacilli, Brucella spp. In China, 90% of brucellosis occurred in six northern agricultural provinces. However, there is an increasing trend of human brucellosis in southern provinces but only limited cases were reported. Our study aims to describe the clinical features and epidemiology of brucellosis in a tertiary hospital of southern china. Methods:A retrospective study was conducted in the past 4 years. Clinical details of brucellosis including occupation, suspected transmission route and complications were retrieved. Serum for tube agglutination test to check Brucella antibody. Blood and aspirate were collected for culture, Vitek 2 and MALDL-TOF MS were used for identification.Results:Thirteen cases of laboratory confirmed brucellosis were encountered in a highly cosmopolitan city Shenzhen of South China between January 2014 and October 2018. Seven of the thirteen patients were male, with age ranging from 29 to 73 years old. Five patients (38.5%) came from Guangdong province, and eight patients (61.5%) came from other provinces. The commonest route of transmission was handling and consumption of infected placenta from goats. Common presenting symptoms include fever, osteoarticular pain and urinary symptoms. Common physical signs were fever, splenomegaly and lymphadenopathy. The commonest complication was spondylodiscitis/ peripheral joint arthritis (n=4), while exotic complications including abdominal aortitis with pseudoaneurysm, hepatic and spleen abscess, soft tissue abscess, and epididymo-orchitis were also observed in 4 other patients. The most life-threating but rare complication of abdominal aortitis in the elderly could be easily missed due to the nonspecific presenting symptom. Conclusions:In summary, brucellosis is increasingly seen in highly cosmopolitan part of southern China. In addition to tuberculosis, typhoid fever and typhus, brucellosis should be considered in the differential diagnosis of fever of unknown origin in this locality. Presence of extensive atherosclerosis in elderly patient may predispose them to endovascular infection by Brucella species.


2017 ◽  
Vol 6 (4) ◽  
pp. 1-6 ◽  
Author(s):  
S Thapa ◽  
L B Sapkota ◽  
P Hamal

Scrub typhus is a potentially fatal zoonotic infection, reported from many parts of Asia including Nepal. There is in­creasing reports of outbreak of Scrub typhus, after the earthquake hit Nepal on April 25, 2015. The recent outbreak of Scrub typhus posed problems in diagnosis and treatment of the disease. It may be related to poor awareness of the disease or lack of suspicion for Scrub typhus which often presents with clinical features indistinguishable from typhoid fever. Since, various parts of Nepal appeared to be suitable hubs for Scrub typhus, the clinical suspicion of Scrub typhus in the differential diagnosis of fever of unknown origin (FUO) is of utmost importance to prevent mortality and morbidity. This is a prospective study conducted in Chitwan Medical College (CMC), Chitwan, Nepal. This study was carried out over a period of 4 months extending from June 2016 to September 2016. A total of 410 serum samples were collected from all patients visiting CMC, clinically suspected of having Scrub typhus infec­tion. The samples were processed for the detection of IgM antibodies for Scrub typhus by ELISA. Results: A total of 410 samples from patients suspected with Scrub typhus infection were processed which included 200 males and 210 females. Out of total 410 samples tested, 181 (44.1%) were seropositive for Scrub typhus. Seropositivity was highest 25.9% among the age group 11-20 years of age. Females were infected more than males. This study implies the re-emergence of Scrub typhus in different regions of Nepal. Although the disease is endemic in our country, it is grossly underdiagnosed owing to non-specific clinical presentation and lack of diagnostic facilities. It is thus suggested that high index of suspicion should be maintained for cases presenting with febrile illness. Infection with Scrub typhus was found high and this calls for an urgent need to introduce vaccine against Scrub typhus. 


2003 ◽  
Vol 114 (1) ◽  
pp. 56-58 ◽  
Author(s):  
Sharlene Gill ◽  
Barbara Melosky ◽  
Lawrence Haley ◽  
Clifford ChanYan

2010 ◽  
Vol 131 (2) ◽  
pp. 166-172 ◽  
Author(s):  
Francini G.M. Pádua ◽  
Thiago F.P. Bezerra ◽  
Richard L. Voegels ◽  
Ricardo F. Bento

Author(s):  
Manish Munjal ◽  
Sanjeev Puri ◽  
Anurag Chaudhary ◽  
Sarit Sharma ◽  
Shubham Munjal ◽  
...  

Background: The demographic profile of patients with frontal sinusitis undergoing surgical intervention in the state of Punjab was analysed. The emphasis was on the age, gender and clinical presentation in this prospective study.Methods: In this prospective study 85 patients of clinically diagnosed frontal sinusitis were randomly selected from the Rhinology clinics of Oto-rhino-laryngology services, Dayanand Medical College and Hospital Ludhiana; in a period of one and a half years (June 2008 to December 2009). All patients were taken up for functional endoscopic sinus surgery with frontal sinusotomy.Results: 3 (3.53%) subjects, with frontal sinusitis were in the pediatric age group, 65 (76.47%) were males 20 (23.53%) females. Males outnumbered females by a ratio of 3.25:1. The age range varied from a minimum of 8 to a maximum of 86 years. 16 (18.8%) had a discharge in the right middle meatus and 21 (24.7%) over the Eustachian tube orifice. Right sided deviation of the nasal septum was in 13 (14.1%) patients, septal spur in 4 (4.7%) and hypertrophy of the inferior turbinate in 7 (8.2%).Conclusions: Frontal sinusitis was seen in all ages with a male predominance. Nasal blockage on the right side rather than frank frontal headache was the primary complaint. Purulent discharge in the middle meatus and over the Eustachian type were the common findings. Pathology on histopathology encountered was mucosal hypertrophy followed by polyp in the sinus. There was no correlation of frontal sinusitis with the weight and height of the patients


1994 ◽  
Vol 2 (1) ◽  
pp. 34-37 ◽  
Author(s):  
David H. Moore ◽  
Kris Ghosh ◽  
Gregory P. Sutton

Background: We report the first known case of spontaneous, atraumatic Clostridium septicum gangrene occurring in a patient with recurrent endometrial adenocarcinoma.Case: A 63-year-old white female undergoing chemotherapy for recurrent endometrial adenocarcinoma presented with right “arthritis-like” shoulder pain. She denied fever, chills, or shoulder trauma. The patient was afebrile and her blood pressure was 100/50. Her right shoulder and upper extremity were remarkable for an area of dark blue discoloration with crepitus. The white blood cell (WBC) count was 8,200/μl with left shift. Serum creatinine, platelet count, and coagulation studies were normal. Computed tomography revealed gas in the right shoulder tissues. A Gram stain of fluid aspirated from the shoulder demonstrated gram-positive spore-forming rods. She declined surgical intervention and expired within hours of admission. Cultures of the right shoulder eventually grew Clostridium septicum.Conclusion: It is imperative to consider clostridial gangrene in the differential diagnosis for any patient with cancer and a fever of unknown origin.


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