scholarly journals HEPATITIS B VIRUS AND UNDERGRADUATE STUDENTS: A STUDY ON LEVELS OF AWARENESS IN UNIVERSITIES ACROSS KARACHI

2018 ◽  
Vol 8 (2) ◽  
pp. 75-79 ◽  
Author(s):  
Mukkaram Ali ◽  
Fauzia Imtiaz ◽  
Muhammad Ahsan Rehman Khan ◽  
Zaeem-ur-Rehman Khan ◽  
Bilal Ahmad ◽  
...  

Background: To assess awareness levels of Hepatitis B virus infection, transmission, treatment and prevention in medical and nonmedical students of Karachi. Methods: Undergraduate students in 6 medical and non-medical universities were randomly approached to fill out a questionnaire. A sample size of 530 students was collected and data was analyzed using SPSS 20 software and chi square tests for significance. Results: Of the 530 students interviewed, 361(68.1%) and 169(31.9%) were identified as medical and non-medical students respectively. Significantly greater knowledge on modes of transmission were noted in medical students as well as overall levels of awareness of Hepatitis B virus, (p=0.001) and (p=0.003) respectively. Conclusion: Both medical and non-medical students showed a moderate level of awareness of Hepatitis B virus, its modes of transmission, treatment and preventive measures. Medical students showed an overall greater level of awareness.

2020 ◽  
Author(s):  
Fazle Rabbi Chowdhury ◽  
Anna L McNaughton ◽  
Mohammad Robed Amin ◽  
Lovely Barai ◽  
Mili Rani Saha ◽  
...  

ABSTRACTBangladesh is one of the world’s top ten burdened countries for viral hepatitis. We investigated an adult fever cohort (n=201) recruited in Dhaka, to determine the prevalence of hepatitis B virus (HBV) infection and to identify cases of occult hepatitis B infection (OBI). HBV exposure (anti-HBc) was documented in 72/201 (36%), and active HBV infection in 16/201 (8%), among whom 3 were defined as OBI (defined as detectable HBV DNA but negative HBsAg). Applying a target-enrichment sequencing pipeline to samples with HBV DNA >3.0log10 IU/ml, we obtained deep whole genome sequences for four cases, identifying genotypes A, C and D. Polymorphisms in the surface gene of the OBI case may account for the negative HBsAg status. We identified mutations associated with nucleos(t)ide analogue resistance, although the clinical significance in this cohort is not known. The high prevalence of HBV in this setting highlights the benefits of offering screening in hospital patients and the importance of HBV DNA testing of transfusion products to reduce the risk of transmission. In order to work towards international Sustainable Development Goal targets for HBV elimination, increased investment is required for diagnosis, treatment and prevention in Bangladesh.


1989 ◽  
Vol 3 (2) ◽  
pp. 145-149 ◽  
Author(s):  
Se-Hoon Lee ◽  
Byung-Kook Lee ◽  
Kwang-Mook Lee ◽  
Kyu-Sang Cho ◽  
Osamu Inoue ◽  
...  

One hundred and sixty five Korean women in a shoe factory in Masan, Korea were evaluated on hepatitis B virus infection by solid-phase radioimmunoassay in 1986. The participants were women of child-bearing ages, mostly in 20's and 30's. About two thirds (105/165) of the subjects had serological evidence of past or present hepatitis B virus infection, and 17% (28/165) were HBsAg-positive. In view of possible risk of vertical transmission of hepatitis B virus, further epidemiological study was considered necessary to establish preventive measures.


2018 ◽  
Vol 3 (6) ◽  
pp. 383-403 ◽  
Author(s):  
Devin Razavi-Shearer ◽  
Ivane Gamkrelidze ◽  
Mindie H Nguyen ◽  
Ding-Shinn Chen ◽  
Pierre Van Damme ◽  
...  

Author(s):  
Ashmaki A. Acchammachary ◽  
Milind Ubale ◽  
Deepali D. Belurkar ◽  
Poorva P. Bhave ◽  
Aniruddha Arjun Malgaonkar ◽  
...  

Background: Medical students are at risk of acquiring hepatitis B virus infection due to occupational contact with patients’ blood or other body fluids. This study was conducted to determine knowledge of hepatitis B virus infection and anti-HBS antibody titer amongst medical students.Methods: This cross-sectional observational study was conducted on medical students who satisfied the intake criteria and gave written informed consent to participate in the study. After Institutional Ethics Committee clearance, written informed consent was obtained and a structured, pre-validated questionnaire (pre-test) was administered to the participants. After an educational session, an identical questionnaire was administered (post-test). For determining anti-HBs titer (vaccinated participants) and HBsAg (non-vaccinated participants), blood was aseptically collected by cubital venepuncture. HBsAg and anti-HBs antibody levels were determined by immuno-chromatographic assay and enzyme-linked immunosorbent assay, respectively.Results: 140 healthy, HBsAg-negative medical students (79 males; 61 females) participated in the present study. There was increased median correct response in the post-test with increased minimum and first quartile. 91 (65%) who were vaccinated against Hepatitis B were enrolled for anti-HBs titer estimation. There was no significant gender difference in mean antibody titer. 19 (20.9%) had inadequate levels of anti-HBS antibodies. 50% seroconversion was seen after single dose of hepatitis B vaccine.Conclusions: It is essential to delve into the logistic aspects of evaluating all medical students for hepatitis B infection, procuring and offering free vaccination and assessing anti-HBS titer of vaccinated individuals.


Author(s):  
Prachie Sharma ◽  
Akshat Sachdeva ◽  
Kapila Kumar ◽  
Sumit Bhateja ◽  
Geetika Arora

BACKGROUND: The scarcity of regional data on Hepatitis B infected population indicates a lack of vigilant attitude towards the infection caused due to Hepatitis B infection. Therefore, the aim of this survey based study is to understand and assess the overall aptitude of students of Manav Rachna Educational Institutions, Faridabad, Haryana, regarding the knowledge, awareness and practices pertaining to Hepatitis B Virus (HBV) infection have been attempted. Additionally to understand the awareness amongst the population not pursuing a medical course, their comparative assessment was drawn with the students of medical courses. MATERIALS AND METHODS: A total of six hundred and fifty undergraduate students from Manav Rachna Educational Institutions, Faridabad (Haryana) participated in this study. A cross sectional validated survey study was conducted amongst the undergraduate medical students. The survey consisted of a questionnaire of fifteen questions pertaining to knowledge, awareness and practice of HBV. To further our understanding, the survey was extended to non medical undergraduate students in order to draw a comparable analysis between the general understandings of the viral infection amongst the uninitiated in this field. RESULTS: The questionnaire was designed with equal number of questions regarding knowledge, awareness as well as practical handling of the disease. The survey was designed in a way which could be understood by population pertaining to medical as well as non medical background. The results of survey depicted statistically significant levels of knowledge, awareness and aptitude for practical handling of the disease. Moreover, comparatively, the level of awareness regarding the infectious disease was vastly lacking among the students of non professional courses. CONCLUSION: Authors concluded that the students from the medical background may be involved to spread awareness among the general masses. KEY WORDS: Hepatitis B, knowledge, awareness, practice, students, survey.


2001 ◽  
Vol 7 (3) ◽  
pp. 526-530
Author(s):  
W. M. Said ◽  
R. Saleh ◽  
N. Jumaian

We aimed to determine the prevalence of hepatitis B surface antigen [HBsAg] among chronic schizophrenia patients in Jordan. Over a period of 12 months, 192 patients [106 male and 86 female] were tested for hepatitis B virus [HBV] by enzyme immunoassay. An equal number of age- and sex-matched healthy controls was also tested. Of the schizophrenia patients, 14 [10 male and 4 female] were positive for HBsAg while only 5 [4 male and 1 female] of the control subjects tested positive. The difference was not statistically significant but it indicates that chronic schizophrenia patients are a risk group for HBV infection and likely to benefit from preventive measures [health education and immunization against HBV].


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