scholarly journals Improvement of the detection limit by radon background reduction method

2016 ◽  
Vol 19 (4) ◽  
pp. 126-130
Author(s):  
Thanh Thien Tran ◽  
Tao Van Chau ◽  
Laurent Ferreux ◽  
Marie Christine Lépy
Keyword(s):  
Detection Limit ◽  
Gamma Spectrometry ◽  
Reduction Method ◽  
Positive Pressure ◽  
Nitrogen Gas ◽  
Simple Method ◽  
Background Reduction ◽  
Radon Daughter ◽  
Clean Air ◽  
Detector Chamber

This paper describes a simple method to reduce the radon background component applied in environmental studies using gamma spectrometry. The radon component can be reduced by introducing either nitrogen gas or clean air into the detector chamber in order to create a positive pressure and further minimize radon intrusion from outside. This method shows that we can minimize the influence of radon daughter background such as 214Pb, 214Bi and 210Pb (from 238U), 212Pb, 212Bi and 208Tl (from 232Th). By the way, the detection limit of the gamma spectrometry is discussed.

A simple method to construct a low-cost immunosensor based on a dithiol-functionalized polydopamine platform

2021 ◽  
Author(s):  
Bo Liu ◽  
Luanying Yang ◽  
Gang Wang ◽  
Sha He ◽  
Xiaobo Wang ◽  
...  
Keyword(s):  
Detection Limit ◽  
Linear Response ◽  
Low Cost ◽  
Covalent Immobilization ◽  
The Self ◽  
Simple Method ◽  
Low Detection Limit

A simple and low-cost electrochemical CEA immunosensor was investigated via the self-polymerization of dopamine and a dithiol compound spacer for the covalent immobilization of antibodies. The designed CEA immunosensor exhibited a linear response and a low detection limit.

Defence Anaesthesia transition from the Tri-Service Anaesthetic Apparatus to the Diamedica Portable Anaesthesia Machine 02

2018 ◽  
Vol 165 (5) ◽  
pp. 351-355
Author(s):  
Jonathan David Pearson ◽  
A Maund ◽  
CP Jones ◽  
E Coley ◽  
S Frazer ◽  
...  
Keyword(s):  
Positive Pressure ◽  
High Fidelity Simulation ◽  
Subject Matter Experts ◽  
Simple Method ◽  
Anaesthesia Machine ◽  
Anaesthesia Equipment ◽  
Ease Of Access ◽  
The Uk ◽  
The Military ◽  
Live Patient

Defence Anaesthesia is changing its draw-over anaesthetic capability from the Tri-Service Anaesthetic Apparatus (TSAA) to the Diamedica Portable Anaesthesia Machine 02 (DPA02). The DPA02 will provide a portable, robust, lightweight and simple method for delivering draw-over volatile anaesthesia with the option of positive pressure ventilation through manual or mechanical operation for paediatric and adult patients. The UK Defence Medical Services uses a modified configuration of the DPA02; this paper seeks to explain the rationale for the differing configurations and illustrates alternative assemblies to support integration with other Defence Anaesthesia equipment. High-fidelity simulation training using the DPA02 will continue to be delivered on the Defence Anaesthesia Simulation Course (DASC). Conformité Européenne accreditation of DPA02 supports future UK live patient training in centres of excellence supervised by subject matter experts; this was not possible with the TSAA. This article is intended to be a key reference for all members of the Defence Anaesthesia team. Alongside other resources, it will be given as precourse learning prior to attending the DASC and the Military Operational Surgical Training. This article will also be issued with all Defence DPA02 units, supporting ease of access for review during future clinical exercises (including validation), prior to supervised live training and on operational deployments.

Detection Limit for Ra-228 in Drinking Water by Gamma Spectrometry

2019 ◽  
pp. 146-161
Author(s):  
Thomas M. Semkow ◽  
Abdul J. Khan ◽  
Traci A. Menia ◽  
Xin Li ◽  
Liang T. Chu ◽  
...  
Keyword(s):  
Drinking Water ◽  
Detection Limit ◽  
Gamma Spectrometry

Determination of glutathione and glutathione disulfide in human whole blood using HPLC with coulometric detection: A comparison with fluorescence detection

2011 ◽  
Vol 76 (4) ◽  
pp. 277-294 ◽  
Author(s):  
Roman Kanďár ◽  
Pavla Žáková ◽  
Miroslava Marková ◽  
Halka Lotková ◽  
Otto Kučera ◽  
...  
Keyword(s):  
Detection Limit ◽  
Whole Blood ◽  
Trichloroacetic Acid ◽  
Signal To Noise Ratio ◽  
Glutathione Disulfide ◽  
Simple Method ◽  
Human Whole Blood ◽  
Coulometric Detection ◽  
Coefficients Of Variation

We describe a relatively simple method for the determination of glutathione (GSH) and glutathione disulfide (GSSG) in human whole blood. We have used an HPLC with coulometric electrochemical detection for the simultaneous measurement of GSH and GSSG. Diluted and filtered trichloroacetic acid extracts were injected directly into the HPLC system and were eluted isocratically on a Polaris 5u C18-A, 250 × 4.6 mm analytical column. Glutathione in samples extracted with trichloroacetic acid and diluted with 1.0 mMhydrochloric acid was stable at 4 °C for at least 8 h. The analytical performance of this method is satisfactory: the intra-assay and inter-assay coefficients of variation were below 10%. Quantitative recoveries from spiked whole blood samples were at intervals 91.6–97.6% for GSH and 85.0–104.4% for GSSG. The linear range is 5.0–2000.0 μmol/l, with a detection limit of 2.1 μmol/l (signal-to-noise ratio = 3) for GSH and 2.0–250.0 μmol/l, with a detection limit of 0.9 μmol/l for GSSG.

Fabrication of Silicon Nanowires by Electron Beam Lithography and Thermal Oxidation Size Reduction Method

2013 ◽  
Vol 832 ◽  
pp. 415-418 ◽  
Author(s):  
Mohammad Nuzaihan Md Nor ◽  
Uda Hashim ◽  
Taib Nazwa ◽  
Tijjani Adam
Keyword(s):  
Electron Beam ◽  
Thermal Oxidation ◽  
Silicon Nanowires ◽  
Electron Beam Lithography ◽  
Reduction Method ◽  
Size Reduction ◽  
Simple Method ◽  
Force Microscopy ◽  
Initial Silicon ◽  
20 Nm

A simple method for the fabrication of silicon nanowires using Electron Beam Lithography (EBL) combined with thermal oxidation size reduction method is presented. EBL is used to define the initial silicon nanowires of dimensions approximately 100 nm. Size-reduction method is employed for reaching true nanoscale of dimensions approximately 20 nm. Dry oxidation of silicon is well investigated process for self-limited size-reduction of silicon nanowires. In this paper, successful size reduction of silicon nanowires is presented and surface topography characterizations using Atomic Force Microscopy (AFM) are reported.

scholarly journals A simple method for positive pressure ventilation during fibreoptic intubation

2015 ◽  
Vol 62 (6) ◽  
pp. 678-679
Author(s):  
J. Matthew Kynes ◽  
Jonathan R. Meserve ◽  
David Selig
Keyword(s):  
Positive Pressure Ventilation ◽  
Fibreoptic Intubation ◽  
Positive Pressure ◽  
Simple Method

Point of care test technology suitable for early detection and monitoring of ischemic stroke

2021 ◽  
Vol 18 ◽  
Author(s):  
Young Mi Lee ◽  
Mi Jung Bae ◽  
Ye Seul Choi ◽  
Eunmi Lee ◽  
Junghwan Cho ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Detection Limit ◽  
Early Detection ◽  
Quantum Dot ◽  
Limit Of Detection ◽  
Point Of Care ◽  
Membrane System ◽  
Arterial Disease ◽  
Simple Method ◽  
Point Of Care Test

Background: Stroke is one of the leading causes of death and disability in adulthood worldwide. A simple and convenient diagnostic method is needed for monitoring high-risk patients for stroke. Few POCTs are available for stroke diagnosis. Soluble blood P-selectin is known as a biomarker for platelet aggregation. Increased expression of P-selectin is observed in coronary artery disease, acute myocardial infarction, stroke and peripheral arterial disease. Objective: A simple method that can measure the increased expression of P-selectin in stroke patients is intended to be used for diagnosis or early detection and hospital monitoring of ischemic stroke. Method: Plasma proteins in blood were separated using a three-layered filter system. Quantum dot and antibody were conjugated to detect biomarkers present in plasma and then measured with a fluorescence spectrophotometer. Results: The detection limit of soluble P-selectin confirmed by immunoassay was 1 ng/ul. In order to increase the sensitivity and simplify the reaction, the detection limit was measured to evaluate the sensitivity of the quantum dot labeled anti P-selectin antibody. As a result, P-selectin of 5 ng/ul or more showed saturation signal intensity, indicating the upper limit of detection, and 10 pg/ul was the lower limit of detection. Conclusion: In this study, we proposed a three-layer filter membrane system that can separate biomarker-rich fractions from whole blood, simplifying the analysis process and improving sensitivity by using quantum dot-labeled antibodies to detect biomarkers. We hope that our system complements the advantages of POCT and can be applied to real clinical applications.

A background reduction method based on empirical mode decomposition for tunable diode laser absorption spectroscopy system

Optik ◽  
2018 ◽  
Vol 158 ◽  
pp. 416-423 ◽  
Author(s):  
Rendi Yang ◽  
Yunfeng Bi ◽  
Qiang Zhou ◽  
Xiaozhou Dong ◽  
Tieliang Lv
Keyword(s):  
Diode Laser ◽  
Empirical Mode Decomposition ◽  
Absorption Spectroscopy ◽  
Reduction Method ◽  
Tunable Diode Laser ◽  
Background Reduction ◽  
Laser Absorption ◽  
Mode Decomposition ◽  
Spectroscopy System ◽  
Diode Laser Absorption

scholarly journals Hybrid superhydrophilic–superhydrophobic micro/nanostructures fabricated by femtosecond laser-induced forward transfer for sub-femtomolar Raman detection

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Xiaodan Ma ◽  
Lan Jiang ◽  
Xiaowei Li ◽  
Bohong Li ◽  
Ji Huang ◽  
...  
Keyword(s):  
Detection Limit ◽  
Femtosecond Laser ◽  
Contact Area ◽  
Fluid Transport ◽  
Sers Substrate ◽  
Simple Method ◽  
Small Areas ◽  
Forward Transfer ◽  
Surface Enhanced Raman ◽  
Target Molecules

Abstract Raman spectroscopy plays a crucial role in biochemical analysis. Recently, superhydrophobic surface-enhanced Raman scattering (SERS) substrates have enhanced detection limits by concentrating target molecules into small areas. However, due to the wet transition phenomenon, further reduction of the droplet contact area is prevented, and the detection limit is restricted. This paper proposes a simple method involving femtosecond laser-induced forward transfer for preparing a hybrid superhydrophilic–superhydrophobic SERS (HS-SERS) substrate by introducing a superhydrophilic pattern to promote the target molecules to concentrate on it for ultratrace detection. Furthermore, the HS-SERS substrate is heated to promote a smaller concentrated area. The water vapor film formed by the contact of the solution with the substrate overcomes droplet collapse, and the target molecules are completely concentrated into the superhydrophilic region without loss during evaporation. Finally, the concentrated region is successfully reduced, and the detection limit is enhanced. The HS-SERS substrate achieved a final contact area of 0.013 mm2, a 12.1-fold decrease from the unheated case. The reduction of the contact area led to a detection limit concentration as low as 10−16 M for a Rhodamine 6G solution. In addition, the HS-SERS substrate accurately controlled the size of the concentrated areas through the superhydrophilic pattern, which can be attributed to the favorable repeatability of the droplet concentration results. In addition, the preparation method is flexible and has the potential for fluid mixing, fluid transport, and biochemical sensors, etc.

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