Pain in Gynecological Cancer

The International Association for the Study of Pain defines pain as “unpleasant sensory and emotional experiences associated with actual or potential tissue damage.” Pain is common among patients with cancer, with the prevalence of pain being 66.4% in advanced metastatic disease or terminal, 55% during anticancer treatment, 39.3% after curative treatment, and moderate to severe pain were reported in 38.0% of all patients. Pain is one of the most common and dreaded symptoms in cancer sufferers, but the exact number of cancer patients who experience pain is difficult to determine. There are a wide variety of studies in defining pain and the tools they use to measure the complexity of this symptom. Good or complete pain control can be achieved in 80-90% of cancer patients. Nevertheless, despite major advances in pain control, cancer-related pain continues to be a major public health problem globally.

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Pain in Gynecological Cancer

BioScientia Medicina ◽

10.32539/bsm.v5i3.322 ◽

2021 ◽

Vol 5 (3) ◽

pp. 580-598

Author(s):

Patiyus Agustiansyah ◽

Aidyl Fitrisyah ◽

Sartika Nopradilova

Keyword(s):

Cancer Patients ◽

Pain Control ◽

International Association ◽

Gynecological Cancer ◽

Public Health Problem ◽

Major Public Health Problem ◽

Patients With Cancer ◽

Anticancer Treatment ◽

Prevalence Of Pain ◽

Experience Pain

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Fatigue in Gynecological Cancer Patients During and After Anticancer Treatment

Journal of Pain and Symptom Management ◽

10.1016/j.jpainsymman.2009.06.011 ◽

2010 ◽

Vol 39 (2) ◽

pp. 197-210 ◽

Cited By ~ 29

Author(s):

Gillian Prue ◽

James Allen ◽

Jacqueline Gracey ◽

Jane Rankin ◽

Fiona Cramp

Keyword(s):

Cancer Patients ◽

Gynecological Cancer ◽

Anticancer Treatment

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Abstract 13145: Differences of Cancer Types in Hospital Mortality in Patients With Venous Thromboembolism

Circulation ◽

10.1161/circ.142.suppl_3.13145 ◽

2020 ◽

Vol 142 (Suppl_3) ◽

Author(s):

Okushi Yuichiro ◽

Kenya Kusunose ◽

Takayuki Ise ◽

Takeshi Tobiume ◽

Koji Yamaguchi ◽

...

Keyword(s):

Big Data ◽

Venous Thromboembolism ◽

Hospital Mortality ◽

Cancer Patients ◽

Biliary Tract ◽

Gynecological Cancer ◽

Cancer Type ◽

Patients With Cancer ◽

Liver Cancers ◽

Cancer Types

Introduction: We sought to evaluate the clinical characteristics and outcomes of patients with cancer-associated VTE, compared with the matched cohort without cancer using real-world big data of VTE. Background: Cancer is associated with a high incidence of Venous Thromboembolism (VTE) and there are many guidelines/recommendations about VTE. However, the prognosis of cancer-VTE patients is not well known because of a lack of big data. Moreover, there is also no knowledge on how cancer type is related to prognosis. Methods: This study was based on the Diagnosis Procedure Combination database in the Japanese Registry of All Cardiac and Vascular Datasets (JROAD-DPC). We identified 28,247 patients who were first hospitalized with VTE from April 2012 to March 2017. 26.0% were cancer patients. Compared with national statistics of cancer incidence in 2015 from National Cancer Center of Japan, the proportion of gynecological cancer patients was higher, but other cancer types had similar prevalence rates. Propensity score (PS) was estimated with logistic regression model, with cancer as the dependent variable and 18 clinically relevant covariates. Results: We included 24,576 patients after exclusion. The median age was 71years (range: 59-80 years), and 42.0% were male. On PS-matched analysis with 12,418 patients, patients with cancer had higher total in-hospital mortality (9.5% vs. 3.8%, P<0.001; OR, 2.72, 95% CI: 2.33-3.19) and in-hospital mortality within 30days (6.8% vs. 3.2%, P<0.001; OR, 2.20, 95% CI: 1.85-2.62). On analysis for each type of cancer, in-hospital mortality in 10 types of cancer was significantly high, especially pancreas (OR: 9.65, 95%CI: 4.31-21.64), biliary tract (OR: 8.36, 95%CI: 2.42-28.89) and liver (OR: 7.33, 95%CI: 1.92-28.02). Conclusions: Patients with cancer had a higher in-hospital mortality for VTE than those without cancer, especially in pancreatic, biliary tract and liver cancers.

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PP553 Study On The Utilization Of Medical Resources In Patients With Malignant Tumors in China

International Journal of Technology Assessment in Health Care ◽

10.1017/s0266462320002007 ◽

2020 ◽

Vol 36 (S1) ◽

pp. 42-42

Author(s):

Yuehua Liu ◽

Tiantian Du ◽

Fan Zhang ◽

Kun Zhao

Keyword(s):

Cancer Patients ◽

Treatment Period ◽

Malignant Tumors ◽

Public Health Problem ◽

Medical Expenditure ◽

Utilization Efficiency ◽

Major Public Health Problem ◽

Medical Resource ◽

Medical Resources ◽

End Stage

IntroductionMalignant tumors have become a major public health problem and their treatment cost is increasing rapidly in China, but treatment aimed at healing diseases or extending patients’ life. There is little empirical research on utilization of healthcare resources of terminally ill cancer patients. In order to explore the optimal treatment decision for patients and provide information for relevant decision makers, this study analyzed the consumption status of medical resources in patients with cancer during the whole treatment period, and the current medical resource utilization efficiency in different levels of hospital for end-stage cancer patients.MethodsThis study was based on the clinical treatment and payment data of 2,536 cases of patients with lung cancer from the medical insurance database during the period of 2007 to 2014 in Hubei province. We retrospectively analyzed patients’ medical expenditure and utilization of different medical resources during their whole treatment period as well as at the end stage.ResultsThe per capita inpatient expenditures of patients under 50 years old was 193,000 CNY (27,451 USD), while that of the patients over 70 years were 80,000–90,000 CNY (11,379–12,802 USD). Secondly, the medical expenditures spent during the last 6 months of life accounted for 66.1 percent of the total expenditures. Lastly, the medical expenditure spent in tertiary hospitals accounted for 95.3 percent of the total expenditure, and the expenditure was 14,200 ± 17,030 CNY (2,019.82 ± 2,422.36 USD) per visit.ConclusionsPopulation aging is not the only factor causing the rise of medical expenditure. The unclear objectives of treatment and the reverse of medical resource allocation are also important factors to boost the growth of medical expenditure. It is necessary to improve the healthcare insurance payment system, strengthen the capacity of primary medical institutions, and develop the palliative care system in China.

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HUBUNGAN PENGENDALIAN NYERI ( PAIN CONTROL ) DENGAN INTENSITAS NYERI PADA PASIEN KANKER DI RSUD DELI SERDANG LUBUK PAKAM TAHUN 2018

JURNAL KEPERAWATAN DAN FISIOTERAPI (JKF) ◽

10.35451/jkf.v1i1.49 ◽

2018 ◽

Vol 1 (1) ◽

pp. 7-11

Author(s):

Herri Novita Tarigan ◽

Astuti Sari

Keyword(s):

Cell Proliferation ◽

Pain Intensity ◽

Cancer Patients ◽

Pain Control ◽

Demographic Data ◽

Surrounding Tissue ◽

Design Data ◽

Patients With Cancer ◽

The Relationship ◽

Uncontrolled Cell Proliferation

Cancer is an abnormal cell growth which tend to be attack the surrounding tissue and spread to other organs which is far away. The cause of cancer is uncontrolled cell proliferation. Whereas the complaints that often appear on patients with cancer is pain. Cancer pain is one result of the most feared cancer patients. In fact, pain is the most recent cancer symptom. When according to the intensity that the patient feel subjectively. This research aimed to analyzed the relationship between pain control with pain intensity on cancer patients. With descriptive correlation research design. Data collection started from February to April 2018. With the number of 96 respondents by using total samplingas the research instrument that used as method of sample collecting, demographic data, pain control questionnaires and observation sheets. The result of the research showed that the sign value is 0,005 which showed the correlation between pain control score with pain intensity is significant correlation value is -0,284. With a negative direction. Wherees the better of pain control means the lower of pain intensity. The correlation between pain control with pain intensity is two way relationship. Suggestion : Hopefully this research can be useful in the future in controlling of pain cancer patients.

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A Multicenter Study of Coronavirus Disease 2019 Outcomes of Cancer Patients in Wuhan, China

10.1101/2020.03.21.20037127 ◽

2020 ◽

Cited By ~ 6

Author(s):

Hongyan Zhang ◽

Linwei Wang ◽

Yuanyuan Chen ◽

Xiaokun Shen ◽

Qun Wang ◽

...

Keyword(s):

Cancer Patients ◽

Laboratory Finding ◽

Clinical Information ◽

Treatment Phase ◽

Severe Illness ◽

Cancer Type ◽

Mild Disease ◽

Patients With Cancer ◽

Global Pandemic ◽

Anticancer Treatment

AbstractBackgroundAt present, there is a global pandemic of coronavirus disease 2019 (COVID-19) pneumonia. For COVID-19 patients, cancer is a coexisting disease that should not be Here, we conducted a multicenter retrospective study to show the clinical information and outcomes of cancer patients infected with COVID-19.MeasurementsMedical records of COVID-19 patients with cancer admitted to hospitals from Jan 5, 2020 to Feb 18, 2020 were collected.ResultsOf the 67 patients (median age: 66 years), the median age of patients with severe illness was older than that of patients with mild symptoms (P<0.001). The proportion of severe patients had co-morbidities was higher than patients with mild disease (P=0.004). During the treatment of COVID-19 pneumonia, tumor progression and recurrence was not observed for those patients still at the anticancer treatment phase. Lymphocytopenia was the main laboratory finding accompanying increased C-reactive protein and procalcitonin in cancer patients, especially in severe cases. By Mar 10, 2020, 18 (26.9%) patients died from COVID-19. The median age of survivors was younger than that of deaths (P=0.014). Lung cancer (n=15, 22.4%) was the most common cancer type and accounted for the highest proportion COVID-19 resulted deaths (33.3%, 5/15). We observed a tendency that patients at the follow-up phase had a better prognosis than that at anticancer treatment phase (P=0.095).ConclusionThis study showed COVID-19 patients with cancer seem to have a higher proportion of severe cases and poorer prognosis. We should pay more intensive attentions to cancer patients infected with COVID-19.

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Basic study of a breast cancer epidemiology among the female patients using a regional data source: Case of Chlef region, Algeria

10.21203/rs.3.rs-1015198/v1 ◽

2021 ◽

Author(s):

MAAMAR BOUKABCHA

Keyword(s):

Public Health ◽

Breast Cancer ◽

Cancer Patients ◽

Cancer Registry ◽

Health Problem ◽

Public Health Problem ◽

Female Breast Cancer ◽

Major Public Health Problem ◽

Breast Cancer Patients ◽

Female Breast

Abstract Purpose Breast cancer is a public health problem. It impact given several, important consequences for reducing this disease. We did this study to know the situation of breast cancer and the development of cancer registry. Methods Epidemiological, statistical and computer tools are used to collect, analysis and process of the data, we used the medical records to know the data information on female breast cancer patients, by collaboration with of Bedje Sisters Public Hospitalise of Chlef (BSPHC) and the Oran Cancer Registry. Results We collected approximately 177 cases of female breast cancer, and approximately 601595 female populations during the year 2016 for Chlef region. The incidence rate is more than 29 cases of female breast cancer patients per 100000 female populations for each year. Female breast cancer patients of Chlef region is a major public health problem according to the 2016 study. Incidence rates this disease are greatly increased between 55 years and 75 years old. Conclusion Prevention, early diagnostic and different care and treatment play an important role in reducing this chronic disease in this region and why not over the worldwide?

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Awareness of Cancer-Related Malnutrition and Its Management: Analysis of the Results From a Survey Conducted Among Medical Oncologists

Frontiers in Oncology ◽

10.3389/fonc.2021.682999 ◽

2021 ◽

Vol 11 ◽

Author(s):

Maurizio Muscaritoli ◽

Emanuele Corsaro ◽

Alessio Molfino

Keyword(s):

Cancer Patients ◽

Public Health Problem ◽

Multidisciplinary Teams ◽

Major Public Health Problem ◽

Negative Consequences ◽

Treatment Optimization ◽

Nutritional Interventions ◽

Effective Strategies ◽

Medical Oncologists ◽

Survey Results

Cancer is a global major public health problem, particularly in Western countries, where it represents the second leading cause of death after cardiovascular disease. Malnutrition is common in cancer patients and differs from starvation-related malnutrition, as it results from a combination of anorexia and metabolic dysregulation, caused by the tumor itself or by its treatment, and causing cachexia. Cancer-associated malnutrition can lead to several negative consequences, including poor prognosis, reduced survival, increased therapy toxicity, reduced tolerance and compliance to treatments, and diminished response to antineoplastic drugs. Guidelines issued by the Ministry of Health in 2017, the most recent ESPEN guidelines and the PreMiO study highlighted an inadequate nutritional support in cancer patients since their first visit, and recommended an optimization of the quality of life of cancer patients in each stage of the disease, also through specific nutritional interventions by multidisciplinary teams. Based on the evidences summarized above, a survey has been carried out on a sample of 300 Italian hospital medical oncologists to evaluate their level of awareness and perception of cancer-related malnutrition and their proposals to implement effective strategies to improve nutritional care in the setting of hospital oncology departments in Italy. The survey results indicate that, despite high levels of awareness among Italian oncologists, malnutrition in cancer patients remains, at least in part, an unmet medical need, and additional efforts are necessary in terms of increased training and hiring of personnel, and of creation of organizational pathways aimed at treatment optimization based on available evidences.

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Profile of Patients with Digestive Tube Cancer Infected With HIV in Two Cancerology Centers in Cameroon

Open Journal of Gastroenterology and Hepatology ◽

10.28933/ojgh-2021-02-2606 ◽

2021 ◽

pp. 47

Author(s):

◽

...

Keyword(s):

Viral Load ◽

Digestive Tract ◽

Public Health Problem ◽

Cd4 Count ◽

Major Public Health Problem ◽

Hiv Diagnosis ◽

Digestive Tube ◽

Patients With Cancer ◽

Digestive Cancers ◽

The Mean

Background: Human Immunodeficiency Virus (HIV) infection is a major public health problem in Africa, which alone recorded 71% of HIV / AIDS-related deaths in 2018. There is a link between the infection to HIV and the occurrence of certain cancers, in particular digestive cancers. Very little data in Africa, especially Cameroon, exists on the association between HIV and digestive cancers. Our goal was to determine the prevalence of HIV in patients with cancer of the digestive tract as well as the factors related to the prognosis of these patients in Cameroon. Methods: We conducted a cross-sectional and analytical study over a 10-year period from January 2010 to December 2019. It was carried out in the general hospitals of the cities of Douala and Yaoundé. We included records of patients with histologically confirmed gastrointestinal cancer. We excluded records of patients with lymphoma or Kaposi’s sarcoma. The data collected were socio-demographic, clinical and paraclinical data. Chi-square test was used to determine statistically significant associations for p <0.05. Results: We collected 294 files, among which 71 had positive HIV serology, either a prevalence of 24.15%. The average age of the patients was 53,7±13,6 years old. The sex ratio was 1.08. The main locations were the colon with 28.7% (N = 20) and the anus with 25.4% (N = 18). At the time of HIV diagnosis, the mean CD4 count at the time of HIV diagnosis was 413,2±189,3/mm3 and the mean viral load was 5129±2786,8copies/mm3. When diagnosed with cancer, the average CD4 count was 287,84±101,7/mm3 and the average viral load was 25385,5±19784,3/mm3. The anal location (p = 0.003), the necrotic appearance (p = 0.001), the poorly differentiated character (p = 0.02) of the tumors and the death of the patients (p = 0.000) were statistically linked to positive HIV serology. Factors associated with the prognosis of HIV positive patients were CD4 count <200 / mm3 (p = 0.002) and the existence of metastases (p = 0.04) Conclusion: The prevalence of HIV in patients with cancer of the digestive tract is 24.15%. The anal location, the necrotic appearance and the undifferentiated nature of the tumors are related to positive HIV serology. Prognostic factors are a CD4 count <200 / mm3 and the existence of metastases.

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Substance Abuse and Drug-Related Death, Suicidal Ideation, and Suicide: A Review

Crisis ◽

10.1027//0227-5910.20.1.28 ◽

1999 ◽

Vol 20 (1) ◽

pp. 28-35 ◽

Cited By ~ 29

Author(s):

Annie Mino ◽

Arnaud Bousquet ◽

Barbara Broers

Keyword(s):

Public Health ◽

Risk Factors ◽

Substance Abuse ◽

Suicidal Ideation ◽

Family Support ◽

Drug Users ◽

Suicide Attempts ◽

Public Health Problem ◽

Major Public Health Problem ◽

Hiv Epidemic

The high mortality rate among drug users, which is partly due to the HIV epidemic and partly due to drug-related accidental deaths and suicides, presents a major public health problem. Knowing more about prevalence, incidence, and risk factors is important for the development of rational preventive and therapeutic programs. This article attempts to give an overview of studies of the relations between substance abuse, suicidal ideation, suicide, and drug-related death. Research in this field is hampered by the absence of clear definitions, and results of studies are rarely comparable. There is, however, consensus about suicidal ideation being a risk factor for suicide attempts and suicide. Suicidal ideation is also a predictor of suicide, especially among drug users. It is correlated with an absence of family support, with the severity of the psychosocial dysfunctioning, and with multi-drug abuse, but also with requests for treatment. Every clinical examination of a drug user, not only of those who are depressed, should address the possible presence of suicidal ideation, as well as its intensity and duration.

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