scholarly journals The Effect of Eight Weeks of Water Resistance Training with Dark Chocolate Consumption on Plasma Levels of Endothelin-1, Nitric Oxide and Quality of Life in Elderly Women

Background: Vascular endothelial cells play an important role in regulating vascular activity by producing vascular active substances such as endothelin-1 and nitric oxide. The aim of this study was to investigate the effect of eight weeks of water resistance training with dark chocolate consumption on plasma levels of endothelin-1, nitric oxide and quality of life in elderly women. Materials and Methods: In this semi-experimental study, 37 elderly women (mean ± standard deviation; age, 65.6 ± 3.1 years; weight 75.71 ± 7.7 kg) were purposefully divided into four complementary groups. Supplementation and exercise, exercise and control were included. The training protocol was performed for eight weeks of water resistance training. Supplementation of 30 grams of 83% dark chocolate daily was used for 8 weeks. Quality of life index was measured by SF-36 evaluation and plasma endolin-1 levels by ELISA and serum nitrite levels as the main metabolite of NO. One-way analysis of variance and Bonferroni’s post hoc test were used for statistical analysis. Results: The results showed that the mean quality of life index in the water resistance training group was significantly higher than the control group in elderly women (p = 0.036). Also, the mean NO levels in the combined group were significantly higher than the control group (p = 0.001). But the mean levels of endothelin-1 in the combined group were significantly lower than the control group (p = 0.012). Conclusion: Based on the present results, it can be concluded that resistance training in water along with consumption of dark chocolate may reduce endothelin-1 levels and increase NO levels to improve endothelial function and increase quality of life in elderly women.

2010 ◽  
Vol 16 (4) ◽  
pp. 480-490 ◽  
Author(s):  
U. Dalgas ◽  
E. Stenager ◽  
J. Jakobsen ◽  
T. Petersen ◽  
HJ Hansen ◽  
...  

Fatigue occurs in the majority of multiple sclerosis patients and therapeutic possibilities are few. Fatigue, mood and quality of life were studied in patients with multiple sclerosis following progressive resistance training leading to improvement of muscular strength and functional capacity. Fatigue (Fatigue Severity Scale, FSS), mood (Major Depression Inventory, MDI) and quality of life (physical and mental component scores, PCS and MCS, of SF36) were scored at start, end and follow-up of a randomized controlled clinical trial of 12 weeks of progressive resistance training in moderately disabled (Expanded Disability Status Scale, EDSS: 3—5.5) multiple sclerosis patients including a Control group ( n = 15) and an Exercise group ( n = 16). Fatigue (FSS > 4) was present in all patients. Scores of FSS, MDI, PCS—SF36 and MCS—SF36 were comparable at start of study in the two groups. Fatigue improved during exercise by —0.6 (95% confidence interval (CI) —1.4 to 0.4) a.u. vs. 0.1 (95% CI —0.4 to 0.6) a.u. in controls ( p = 0.04), mood improved by —2.4 (95% CI —4.1 to 0.7) a.u. vs. 1.1 (—1.2 to 3.4) a.u. in controls ( p = 0.01) and quality of life (PCS—SF36) improved by 3.5 (95% CI 1.4—5.7) a.u. vs. —1.0 (95% CI —3.4—1.4) a.u. in controls ( p = 0.01). The beneficial effect of progressive resistance training on all scores was maintained at follow-up after further 12 weeks. Fatigue, mood and quality of life all improved following progressive resistance training, the beneficial effect being maintained for at least 12 weeks after end of intervention.


2020 ◽  
Vol 13 (11) ◽  
Author(s):  
Farzad Allameh ◽  
Abbas Basiri ◽  
Saleh Ghiasy ◽  
Atefeh Javadi ◽  
Seyyed Ali Hojjati ◽  
...  

Background: Radiotherapy (RT) is a choice to manage pelvic organ malignancies that can affect bladder; therefore, it causes radiation cystitis with some bothering urinary symptoms and decreasing the patient’s quality of life. Intravesical hyaluronic acid (HA) is an agent with promising results in some studies for cystitis, and Cystistat is a derivative of hyaluronic acid. Objectives: This clinical trial aimed at evaluating the effects of intravesical instillation of Cystistat on symptoms of radiation cystitis and quality of life (QOL). Methods: A total of 58 patients with radiation cystitis were randomized in 2 groups (case: 30, control: 28). One group received intravesical Cystistat, the other received normal saline weekly for up to 4 weeks and then monthly for up to 2 months. Hematuria, Visual Analog scale (VAS) and QOL based on King’s Health questionnaire were compared before and 3, 6 and 9 months after intravesical instillation. Results: The mean age of the patients was 63.93 ± 10.89 years old. The mean of each sub-category of QOL and total score of QOL, as well as, VAS score were significantly improved in comparison to the control group at each time of follow-ups (P < 0.05). Hematuria was significantly different in the 3rd, 6th and 9th month of follow-ups (P < 0.05). Conclusions: Findings showed that patients with radiation cystitis could significantly benefit from intravesical instillation of HA, their hematuria would be successfully resolved rather than control group in addition to lowering the VAS score, so their QOL would be improved.


Author(s):  
Maryam Mousavi ◽  
Farshad Ghazalian

Introduction: Improving balance in the daily lives of the elderly plays an important role, especially in reducing their risk of falling. Therefore, the aim of the present study was to investigate the effect of eight weeks water resistance training with dark chocolate supplementation on the balance of the elderly.Methods: In this study, 38 elderly people with an age range of 73-60 years were randomly divided into four groups. Participants in groups, included water resistance training and water resistance training + dark chocolate, performed water resistance training for eight weeks. In this period, groups of dark chocolate and water resistance training + dark chocolate, consumed 6 pieces of dark chocolate 83%, 5 gr per day, and the control group did not have any training or supplementation. The stork test (flamingo) was used to assess balance. The results of covariance analysis (ANOVA) showed that there was a statistically significant difference between the four groups. Data were evaluated using Excel and SPSS-25 (p≤ 0.05). Results: The adjusted means after eliminating the effect of pre-test scores showed that the water resistance-training group had a higher mean than the other three groups and the weakest scores belonged to the control group. The results of other groups were as followed: experimental group 18.77, chocolate group 16.88, combined group (water resistance training + dark chocolate) 17.24 and control group 9.77. The results of Benferoni test showed that there was a significant difference between the water resistance training group and the control group (p = 0.006). Conclusion: According to the results of this study, it seems that eight weeks of water resistance training and dark chocolate supplementation can improve the balance and quality of life of the elderly.


2015 ◽  
Vol 2 (2) ◽  
Author(s):  
Sheida Jabalameli ◽  
Hamid Taher Neshat Doost ◽  
Mohammad Bagher Kajbaf ◽  
Hossein Molavi

Generalized Anxiety Disorder (GAD) is one of the most common anxiety disorders. It has been reported that psychological treatments like Cognitive-Behavioral Therapy (CBT) is effective for patients with GAD. The purpose of the present research was to investigate the effectiveness of CBT on Quality of Life (QOL) and worry in patients with GAD. A sample of 30 patients with GAD who had been referred to psychiatry offices in Isfahan, Iran were selected and assigned into an experimental group (n=15) and a control group (n=15) randomly.  The experimental group received CBT in 8 weekly sessions. All participants completed the World Health Organization Quality Of Life-Brief (WHOQOL-BREF) questionnaire and the Penn State Worry Questionnaire (PSWQ) at pretest, posttest and follow up. The results of MANCOVA showed that the mean scores of QOL in the experimental group was significantly higher than the control group at the posttest and follow up (P<0.05) and the mean scores of worry in the experimental group was significantly lower than the control group at the posttest and follow up (P<0.05) It is concluded that CBT can be applied for the patients with GAD as a useful psychological treatment. In general, CBT can improve QOL and decrease worry in patients with GAD.


2021 ◽  
Vol 10 (17) ◽  
pp. 3826
Author(s):  
Juan Rodríguez-Mansilla ◽  
Abel Mejías-Gil ◽  
Elisa María Garrido-Ardila ◽  
María Jiménez-Palomares ◽  
Jesús Montanero-Fernández ◽  
...  

Background: The functional deficits in people with fibromyalgia can be related to the level of physical activity performed. This study investigated the effectiveness of an active exercise programme versus exercise for well-being improving pain, flexibility, static balance, perceived exertion and quality of life of women with fibromyalgia; Methods: A randomised, single-blind, controlled trial was conducted. A total of 141 of women diagnosed with fibromyalgia were enrolled and randomised to an active exercise program group (n = 47), where they performed physical active exercises, an exercise for well-being group (n = 47), which performed the Qi Gong exercises named ‘the twenty Wang Ziping figures for health and longevity’, and a control group (n = 47), which did not receive any intervention, for a period of 4 weeks. Measures were taken at baseline and after the treatment. The primary outcome measures were static balance and centre of gravity (Wii-Fit Nintendo ©), flexibility (test de Wells and Dillon), pain (Visual Analogue Scale) and quality of life (Spanish-Fibromyalgia Impact Questionnaire). The secondary outcome measure was the perceived exertion during activity (BORG Scale). Results: In total, 93 participants completed the study. The mean value of the age was 52.24 ± 6.19. The post intervention results showed statistically significant improvements in the exercise for well-being and the active exercise programme groups vs. the control group in relation to pain (p = 0.006 active exercise programme group, p = 0.001 exercise for well-being group), static balance (p < 0.001 active exercise programme group) and quality of life (p < 0.001 active exercise programme group, p = 0.002 exercise for well-being group). In addition, the mean scores related to perceived fatigue during the sessions were 6.30 ± 1.88 for the active exercise programme group and 5.52 ± 1.55 for the exercise for well-being group. These differences were not significant. Conclusions: The active exercise program and exercise for well-being improved flexibility, static balance, pain and quality of life of women with fibromyalgia. The participants of the active exercise programme achieved better results that those of the exercise for well-being.


Author(s):  
Ergün Parmaksız ◽  
Hüseyin Demirbilek

Dialysis causes many psycho-social problems in patients with chronic renal failure and decreases their quality of life by increasing their anxiety. We aimed to determine the influence of artistic activities on quality of life and reducing or eliminating dialysis anxiety.Methods. Among 180 hemodialysis patients, 8 patients were randomly selected as a study group and 8 patients as a control group. We performed our theater rehearsals in 16 sessions, two hours per week. State-Trait Anxiety Inventory (STAI), STAII and  Social Anxiety Scales (SAS) were employed in both groups before and after the play. Results. The means of the eighth-month SAS fear and avoidance measures of the study group were found to be significantly lower than the control group and significantly lower than the baseline. The mean difference of the initial eighth-month SAS fear and avoidance in the study group was statistically significantly higher than the control group.Initial and eighth month SAS fear and avoidance difference averages of the study group were found statistically significantly higher than the control group.Conclusions. We determined that the therapies to be done with art have an important place in relieving or reducing anxiety in hemodialysis patients. In addition, it was the opinion that our patients would make positive contributions to their quality of life. However, further studies are needed to demonstrate whether theater rehearsals reduce anxiety in hemodialysis patients.


2021 ◽  
Author(s):  
Payam Sari Aslani ◽  
Maryam Hassanpour ◽  
Omid Razi ◽  
Beat Knechtle ◽  
Abdolhossein Parnow

Abstract Purpose The benefits of resistance training (RT) for migraineurs appears to be lacking although beneficial of aerobic training have been shown in previous studies. The aim of current study, therefore, is to investigate the influence of RT on migraine headache indices, upper and lower-body strength, and quality of life (QOL) in women with migraine disorders. Methods Twenty female migraine patients who were referred by a neurologist were randomly assigned in two groups including RT group (n = 10) and control (CON) group (n = 10). The RT protocol consisted of 8 weeks, 3 sessions per week, 45–60 min per session. Visual Analog Scale (VAS) and pain diary were utilized to measure the subjects' migraine indices including duration, pain severity, and frequency within 48 h pre- and post-training protocol. Patients in Control group (CON) has been refrained from regular exercise during this study. The quality of life (QOL) and muscular strength were measured by the Headache Impact Tests (HIT) and one-repetition maximum (1RM) test, respectively, for 48 h pre- and post-training protocol. Results The RT resulted in a significant decrease in the migraine indices (headache intensity, frequency, and duration) (p = 0.02, p = 0.001, p = 0.04, respectivetly). Increased quality of life and chest and leg muscular strength significantly (p = 0.001 for all) were also showed after 8-week RT protocol. However, there was not any significant differences between groups considering, BMI and waist-hip ratio (WHR) after executing RT protocol (p > 0.05). Conclusion Based on results of current study that mainly had a positive trend, it could state that RT protocol with special considering for migraine patients is probably an alternative therapy or augmentative complement to established interventions for migraine treatment.


2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Zahra Akbari Namvar ◽  
Reza Mahdavi ◽  
Masood Shirmohammadi ◽  
Zeinab Nikniaz

Abstract Background In this trial, we investigated the effect of a group-based education program on gastrointestinal (GI) symptoms and quality of life (QOL) in patients with celiac disease (CD). Method In the present study, 130 patients with CD who were on a GFD for at least 3 months, randomly assigned to receive group-based education (n = 66) or routine education in the celiac clinic (n = 64) for 3 months. We assessed gastrointestinal symptoms and quality of life using the gastrointestinal symptom rating scale (GSRS) questionnaire and SF-36 questionnaire at baseline and 3 months after interventions. Results The mean age of the participants was 37.57 ± 9.59 years. There were no significant differences between the two groups regarding the baseline values. Results showed that the mean score of total GSRS score in the intervention group was significantly lower compared with the control group 3 months post-intervention (p = 0.04). Also, there was a significant difference in the mean score of SF-36 between the two groups 3 months post-intervention (p = 0.02). Conclusion Results showed that group-based education was an effective intervention in patients with celiac disease to improve gastrointestinal symptoms and quality of life. Trial registration IRCT code: IRCT20080904001197N21; registration date: 5/23/2019.


2019 ◽  
Vol 120 ◽  
pp. 113 ◽  
Author(s):  
Rodrigo Ramirez-Campillo ◽  
Cristian Alvarez ◽  
Antonio García-Hermoso ◽  
Carlos Celis-Morales ◽  
Robinson Ramirez-Velez ◽  
...  

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