scholarly journals Treating Ichthyotoxin Poisoning Induced by Gar ‎Eggs Ingestion

2020 ◽  
Vol 10 (3) ◽  
pp. 31548
Author(s):  
Hailey Martin ◽  
Peter Akpunonu
Keyword(s):  
Case Report ◽  
North America ◽  
Freshwater Fish ◽  
Specific Treatment ◽  
Care Providers ◽  
Children's Hospital ◽  
Children’S Hospital

Background: A Gar is a primarily freshwater fish that resides in North America. The flesh of a garfish is edible; however, the eggs and any meat surrounding the eggs are highly toxic to humans. The toxicity is induced by the protein ichthyotoxin. Case Report: The studied patient was an 18-year-old male who ingested 2-3 spoons full of gar eggs in their residence place. Each spoon full contained 40-50 eggs. The estimated total amount of consumed eggs equaled 3 teaspoons. Approximately one hour after eating the eggs, the patient began to feel unwell. Upon arrival at the local Children’s Hospital, the patient was experiencing nausea, vomiting, diarrhea, and sweating. Conclusion: Patients affected by gar eggs should be treated symptomatically, given there is no antidote or specific treatment for ichthyotoxin. Further research is required on the mechanism that makes ichthyotoxin toxic. Luckily, the presented patient presented no seizures due to the toxin and the care providers could manage the related symptoms.

scholarly journals A113 COST SAVINGS OF SEROLOGIC VERSUS BIOPSY PROVEN DIAGNOSIS OF PEDIATRIC CELIAC DISEASE

2020 ◽  
Vol 3 (Supplement_1) ◽  
pp. 131-132
Author(s):  
M Wiepjes ◽  
H Q Huynh ◽  
J Wu ◽  
M Chen ◽  
L Shirton ◽  
...  
Keyword(s):  
Health Care ◽  
Celiac Disease ◽  
North America ◽  
Cost Saving ◽  
Health Care System ◽  
Cost Savings ◽  
Serologic Diagnosis ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Care System

Abstract Background Celiac disease (CD) affects approximately one percent of the population in Canada and the United States. At present, endoscopic diagnosis (ED) of CD remains the gold standard in North America, despite mounting evidence and validated European guidelines for serologic diagnosis (SD). Within publicly funded healthcare systems there is pressure to ensure optimal resource utilization and cost efficiency, including for endoscopic services. At Stollery Children’s Hospital, Edmonton, Canada, we have adopted serologic diagnosis as routine practice since 2016. Aims The aim of this study is to estimate cost savings, i.e. hard dollar savings and capacity improvements, to the health care system as well as impacts on families in regard to reduced work days lost and missing child school days for SD versus ED. Initial cost saving data is presented. Methods Micro-costing methods were used to determine health care resource use in patients undergoing ED or SD from 2017–2018. SD testing included anti-tissue glutaminase antibody (aTTG) ≥200IU/mL (on two occasions), human leukocyte antigen (HLA) DQA5/DQ2, blood sampling, transport and laboratory costs. ED diagnosis included gastroenterologist, anesthetist, OR equipment, staff, overhead and histopathology. Cost of each unit of resource was obtained from the schedule of medical benefits (Alberta) and reported average ambulatory cost for day hospital endoscopy for Stollery Children’s Hospital determined in 2016; reported in CAN$. Results Between March 2017-December 2018, 473 patients were referred for diagnosis of CD; 233 had ED and 127 SD. Estimated cost for ED was $1240 per patient; for SD was $85 per patient (6.8% of ED cost). Based on 127 patients not requiring endoscopy and a cost saving of $1155 per patient there was a total cost savings of $146,685 over 22 months. Conclusions A SD approach presents a significant cost savings to the public health care system. It also frees up valuable endoscopic resources, and limits exposure of children to the immediate and long-term risks associated with anesthesia and biopsy. SD also decreases time to diagnosis and the cost of the process to families (lost days of school/work, travel costs etc.). Our costing data can be used in combination with mounting evidence on the test performance of SD versus ED to determine cost-effectiveness of serological diagnosis for pediatric CD. Given the potential for cost saving and more efficient operating room utilization, SD for pediatric CD warrants further investigation in North America. Funding Agencies None

Fatal Chloroquine Poisoning in a Child: Experience With Peritoneal Dialysis

PEDIATRICS ◽  
1975 ◽  
Vol 55 (4) ◽  
pp. 536-538
Author(s):  
William P. McCann ◽  
Robert Permisohn ◽  
P. A. Palmisano
Keyword(s):  
Peritoneal Dialysis ◽  
Case Report ◽  
The Body ◽  
Chloroquine Overdose ◽  
Children's Hospital ◽  
Chloroquine Poisoning ◽  
Child Experience ◽  
Children’S Hospital ◽  
Chloroquine Diphosphate ◽  
Black Boy

Chloroquine overdose is commonly fatal in children.1 We report here such a case in which peritoneal dialysis was tried. Analyses of tissues, serum, urine, and dialysate for chloroquine confirmed the diagnosis and indicated that little of this drug was removed from the body by dialysis. CASE REPORT A healthy 28-month-old black boy weighing 17.17 kg was seen holding two 500-mg chloroquine diphosphate (Aralen) tablets from a relative's purse about 3:30 PM one afternoon. One-half hour later he was found unconscious and was brought to the Children's Hospital, arriving at 5 PM apneic and with fixed, dilated pupils. It was stated that breathing stopped just before arrival.

scholarly journals Case report of mesenteric lymphadenopathy in Gaucher disease: rare and benign complication

2021 ◽  
Vol 20 (1) ◽  
pp. 168-169
Author(s):  
M. Khalili ◽  
M. Gholamzadeh Baeis ◽  
M. Alaei
Keyword(s):  
Case Report ◽  
Ct Scan ◽  
Gaucher Disease ◽  
Epigastric Pain ◽  
Initial Examination ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
One Year

A 10-year-old boy known case of Gaucher disease about 2 years ago was admitted with nausea, vomiting and epigastric pain from 3 days before hospitalization to Mofid Children’s hospital, Tehran, Iran. On the initial examination, no abnormalities were found except for splenomegaly and brief tenderness on the spleen. In secondary paraclinical evaluations (with Ultrasound and Ct-scan), we noticed mesenteric lymphadenopathy in the patient. The lesions remained unchanged and no significant changes were observed in the clinical and laboratory evaluations of the patient during one-year follow-up period. This is a rare and benign manifestation of Gaucher disease, which is usually monitored and does not require any intervention without signs of malignancy or severe space occupying effects 

Shigellosis in the First Week of Life

PEDIATRICS ◽  
1973 ◽  
Vol 52 (3) ◽  
pp. 437-438
Author(s):  
Leslie L. Barton ◽  
Larry K. Pickering
Keyword(s):  
Urinary Tract Infection ◽  
Case Report ◽  
Urinary Tract ◽  
Tract Infection ◽  
Shigella Flexneri ◽  
Bloody Diarrhea ◽  
Third Trimester ◽  
Children's Hospital ◽  
Children’S Hospital

The diagnosis of shigellosis is only rarely considered in the infant whose diarrhea commences during the first week of life. Haltalin1 reported six cases and reviewed seven others that had appeared in the literature up until 1967. Three other cases have been reported.2-4 We would like to describe an additional infant with onset of diarrhea due to Shigella flexneri infection on her second day of life. Case Report Patient C.E. (SLCH #72-6528) was admitted to St. Louis Children's Hospital at 36 hours of age with fever and bloody diarrhea. The mother had a third trimester urinary tract infection treated with parenteral ampicillin. No diarrhea was noted during her pregnancy.

Nasal Glioma

PEDIATRICS ◽  
1965 ◽  
Vol 35 (2) ◽  
pp. 342-344
Author(s):  
KENNETH G. JAMIESON
Keyword(s):  
Case Report ◽  
Left Nostril ◽  
Nasal Deformity ◽  
Provisional Diagnosis ◽  
Nasal Bridge ◽  
Children's Hospital ◽  
Nasal Glioma ◽  
Children’S Hospital ◽  
The Brain

An intranasal glioma presenting at birth as a readily visible polyp without any evidence of nasal deformity is an uncommon lesion. The purpose of this report is to record one such case in which the site of attachment of the glioma to the brain was studied at operation. Case Report On the day after his birth, August 26, 1958, a boy (A.R.) was referred to the Brisbane Children's Hospital with a provisional diagnosis of nasal encephalocoele. A reddish fleshy lump was to be seen just within the left nostril. There was no other evidence of nasal abnormality, and, in particular, the nasal bridge was normal.

Oculoglandular Tularemia in an Inner City Child

PEDIATRICS ◽  
1973 ◽  
Vol 51 (3) ◽  
pp. 564-566
Author(s):  
Marshall E. Bloom ◽  
William T. Shearer ◽  
Leslie L. Barton ◽  
Edward Mallinckrodt
Keyword(s):  
Case Report ◽  
Inner City ◽  
Human Disease ◽  
Cervical Lymphadenopathy ◽  
Children's Hospital ◽  
Recent Advances ◽  
Children’S Hospital ◽  
The City

Since the 1968 Vermont epidemic of tularemia, human disease has been reported in all of the 50 states.1 This brief report draws attention to tularemia as a contemporary pediatric problem, highlights the recent advances in diagnosis,2,3 and points out that it may occur in city as well as in country children. Case Report A 6-year-old boy (SLCH-88133) from the city of St. Louis was admitted to St. Louis Children's Hospital on January 12, 1972, because of preauricular and cervical lymphadenopathy. Two months prior to admission he developed epiphora, erythema, and edema of his right eye. Within two days, lethargy, fever (104 F) and painful swelling of the entire right side of his face and neck were noted.

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