scholarly journals BACTERIOLOGICAL ANALYSIS OF DONOR HUMAN MILK IN MILK BANK IN AN INDIAN SETTING

2017 ◽  
Vol 04 (01) ◽  
pp. 7-9 ◽  
Author(s):  
Poonam H Singh ◽  
Amita Uday Surana ◽  
Vaishali Chaudhari
Keyword(s):  
Human Milk ◽  
Bacteriological Analysis ◽  
Donor Human Milk ◽  
Milk Bank ◽  
Indian Setting

scholarly journals SARS-CoV-2 in human milk is inactivated by Holder pasteurization but not cold storage

2020 ◽  
Author(s):  
Gregory J. Walker ◽  
Vanessa Clifford ◽  
Nidhi Bansal ◽  
Alberto Ospina Stella ◽  
Stuart Turville ◽  
...  
Keyword(s):  
Viral Load ◽  
Human Milk ◽  
Cold Storage ◽  
Control Medium ◽  
Live Virus ◽  
Donor Human Milk ◽  
Milk Bank ◽  
The Stability ◽  
Milk Banks ◽  
Mother’S Own Milk

ABSTRACTAs the COVID-19 pandemic evolves, human milk banks worldwide continue to provide donor human milk to vulnerable infants who lack access to mother’s own milk. Under these circumstances, ensuring the safety of donor human milk is paramount, as the risk of vertical transmission of SARS-CoV-2 is not well understood. Here, we investigate the inactivation of SARS-CoV-2 in human milk by pasteurisation, and the stability of SARS-CoV-2 in human milk under cold storage (freezing or refrigeration). Following heating to 63°C or 56°C for 30 minutes, SARS-CoV-2 replication competent (i.e. live) virus was undetected in both human milk and the control medium. Cold storage of SARS-CoV-2 in human milk (either at 4°C or - 30°C) did not significantly impact infectious viral load over a 48 hour period. Our findings demonstrate that SARS-CoV-2 can be effectively inactivated by Holder pasteurisation, and confirm that existing milk bank processes will effectively mitigate the risk of transmission of SARS-COV-2 to vulnerable infants through pasteurised donor human milk.

Ebola Virus and Marburg Virus in Human Milk Are Inactivated by Holder Pasteurization

2017 ◽  
Vol 33 (2) ◽  
pp. 351-354 ◽  
Author(s):  
Erin Hamilton Spence ◽  
Monica Huff ◽  
Karen Shattuck ◽  
Amy Vickers ◽  
Nadezda Yun ◽  
...  
Keyword(s):  
Human Milk ◽  
Ebola Virus ◽  
Culture Media ◽  
Plaque Assay ◽  
Marburg Virus ◽  
Donor Human Milk ◽  
Milk Bank ◽  
Viral Plaque ◽  
High Risk Infants ◽  
Milk Banks

Background: Potential donors of human milk are screened for Ebola virus (EBOV) using standard questions, but testing for EBOV and Marburg virus (MARV) is not part of routine serological testing performed by milk banks. Research aim: This study tested the hypothesis that EBOV would be inactivated in donor human milk (DHM) by standard pasteurization techniques (Holder) used in all North American nonprofit milk banks. Methods: Milk samples were obtained from a nonprofit milk bank. They were inoculated with EBOV (Zaire strain) and MARV (Angola strain) and processed by standard Holder pasteurization technique. Plaque assays for EBOV and MARV were performed to detect the presence of virus after pasteurization. Results: Neither EBOV nor MARV was detectable by viral plaque assay in DHM or culture media samples, which were pasteurized by the Holder process. Conclusion: EBOV and MARV are safely inactivated in human milk by standard Holder pasteurization technique. Screening for EBOV or MARV beyond questionnaire and self-deferral is not needed to ensure safety of DHM for high-risk infants.

scholarly journals Human milk banks in the response to COVID-19: a statement of the regional human milk bank network for Southeast Asia and beyond

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Estrella Olonan-Jusi ◽  
Paul G. Zambrano ◽  
Vu H. Duong ◽  
Nguyen T. T. Anh ◽  
Nant S. S. Aye ◽  
...  
Keyword(s):  
Southeast Asia ◽  
Human Milk ◽  
Newborn Care ◽  
World Health ◽  
National Guidelines ◽  
Donor Human Milk ◽  
Skin Contact ◽  
Milk Bank ◽  
Human Milk Bank ◽  
Milk Banks

Abstract Background The World Health Organization (WHO) recommendations on infant feeding in the context of COVID-19 uphold standing recommendations for breastfeeding, non-separation, and skin-to-skin contact, including the use of donor human milk when mother’s own milk is not available. Insufficient guidance on the use of donor human milk and the role of human milk banks in the pandemic response COVID-19 clinical management guidelines in seven countries in Southeast Asia are not aligned with WHO recommendations despite the lack of evidence of transmission through either breastmilk or breastfeeding. The use of safe donor human milk accessed through human milk banks is also insufficiently recommended, even in countries with an existing human milk bank, leading to a gap in evidence-based management of COVID-19. This highlights long-standing challenges as well as opportunities in the safe, equitable, and resilient implementation of human milk banks in the region. Conclusions This statement reflects the expert opinion of the Regional Human Milk Bank Network for Southeast Asia and Beyond on the need to revisit national guidelines based on the best evidence for breastfeeding during the COVID-19 pandemic, to incorporate human milk bank services in national obstetric and newborn care guidelines for COVID-19 where possible, and to ensure that operations of human milk banks are adapted to meet the needs of the current pandemic and to sustain donor human milk supply in the long-term. The Network also recommends sustained engagement with the global human milk bank community.

scholarly journals Improving donor human milk collection in a hospital without a human milk bank: a quality improvement initiative at an urban tertiary-care teaching hospital

2021 ◽  
Vol 10 (Suppl 1) ◽  
pp. e001467
Author(s):  
Reema Garegrat ◽  
Nandini Malshe ◽  
Pradeep Suryawanshi ◽  
Suprabha K Patnaik
Keyword(s):  
Quality Improvement ◽  
Human Milk ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Quality Improvement Initiative ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Donor Human Milk ◽  
Milk Bank ◽  
Human Milk Bank

Feed intolerance and necrotising enterocolitis (NEC) are challenges while treating sick neonates. These can be reduced by giving human milk, but adequate availability of mother’s own milk or pasteurised donor human milk (PDHM) is a challenge in neonatal setups, like ours, without an attached human milk bank. Hence, this quality improvement initiative was taken to improve donor human milk collection in our urban tertiary-care teaching hospital, to at least 500 mL per week in 4 weeks. After analysing the problem, our quality improvement team identified a shortage of human milk donation that was due to low awareness among the stakeholders and lack of a system to collect and store human milk and transport it to a milk bank. The team first established a system of supplies needed for milk collection, storage and transportation. It then tested change idea of information, education and counselling to increase milk donation. The team carried out a few plan-do-study-act cycles (individual and group counsellings, and usage of videos and information leaflets) to test the change ideas and adapted a few and abandoned some. During this journey, the milk collection increased to above the target amount. Various challenges were addressed, and there was a need for constant motivation of the stakeholders, especially the mothers, and now there is sustained milk donation in the setup. This is incorporated in the standard operating procedure and as a quality indicator of the unit for sustaining the changes in the unit. Our initiative can be replicated in other setups for increasing collection of donor human milk. Greater PDHM availability for sick neonates will, in effect, reduce NEC and feeding intolerance rates, leading to reduced hospital stay, morbidity, mortality and economic burden.

Establishment, operation and development of a donor human milk bank

2013 ◽  
Vol 89 ◽  
pp. S7-S9 ◽  
Author(s):  
Augusto Biasini ◽  
Marcello Stella ◽  
Laura Malaigia ◽  
Mariachiara China ◽  
Milena Azzalli ◽  
...  
Keyword(s):  
Human Milk ◽  
Donor Human Milk ◽  
Milk Bank ◽  
Human Milk Bank

Best practice guidelines for the operation of a donor human milk bank in an Australian NICU

2007 ◽  
Vol 83 (10) ◽  
pp. 667-673 ◽  
Author(s):  
B.T. Hartmann ◽  
W.W. Pang ◽  
A.D. Keil ◽  
P.E. Hartmann ◽  
K. Simmer
Keyword(s):  
Human Milk ◽  
Practice Guidelines ◽  
Best Practice ◽  
Donor Human Milk ◽  
Best Practice Guidelines ◽  
Milk Bank ◽  
Human Milk Bank

What are Optimal Bacteriological Screening Test Cut-Offs for Pasteurized Donor Human Milk Intended for Feeding Preterm Infants?

2020 ◽  
pp. 089033442098101
Author(s):  
Vanessa Clifford ◽  
Laura D. Klein ◽  
Christine Sulfaro ◽  
Tass Karalis ◽  
Veronica Hoad ◽  
...  
Keyword(s):  
Human Milk ◽  
Clinical Excellence ◽  
Screening Criteria ◽  
Acceptance Criterion ◽  
Donor Human Milk ◽  
Safety Risks ◽  
Food Standards ◽  
Milk Bank ◽  
Microbial Screening ◽  
The Impact

Background Definitive criteria for microbial screening of pasteurized donor human milk are not well established and international recommendations vary. Aims (1) To review pasteurized donor human milk batch discard due to failed microbial screening criteria at our milk bank (following United Kingdom National Institute of Clinical Excellence guidelines), and (2) to compare our known milk discard proportion with estimated milk discard proportions that would be required by other international milk bank guidelines. Methods We reviewed our microbial screening results ( N = 783) over 18-months (July 2018-December 2019) and compared our known milk discard proportion with estimated milk discard proportions using other international milk bank guidelines. Results Of samples, n = 50 (6.4%) failed pre-pasteurization screening, most commonly due to the presence of >104 CFU/mL Enterobacterales in the pre-pasteurization sample ( n = 30; 3.8%). Two (0.3%) samples failed post-pasteurization screening, with Bacillus cereus identified in both cases, resulting in total discard proportion of 6.7% ( n = 52) of batches. Applying European Milk Bank Association recommended bacterial screening criteria, approximately 23.3% ( n = 183) of milk batches would have been discarded. Conclusions Further research is required to justify the stringent European Milk Bank Association recommendations for pre-pasteurization discard criteria, although we believe that a post-pasteurization acceptance criterion of <1 CFU/mL is appropriate and aligns with international guidance. Further work is needed to understand pasteurized donor human milk microbiological safety risks, to better integrate screening criteria within current food standards regulation, and to consider risk-based assessment including the impact on availability and affordability.

scholarly journals Milk Bank Pooling Practices Impact Concentrations and Variability of Bioactive Components of Donor Human Milk

2020 ◽  
Vol 7 ◽  
Author(s):  
Bridget E. Young ◽  
Katherine Murphy ◽  
Laraine L. Borman ◽  
Rebecca Heinrich ◽  
Nancy F. Krebs
Keyword(s):  
Human Milk ◽  
Bioactive Components ◽  
Donor Human Milk ◽  
Milk Bank

scholarly journals Eight-year Operation Status and Data Analysis of the First Human Milk Bank in East China

2021 ◽  
Author(s):  
Xiaoshan Hu ◽  
Xue Chu ◽  
Jun Zhang ◽  
Feng Liu ◽  
Xiaohui Chen ◽  
...  
Keyword(s):  
Human Milk ◽  
Electronic Monitoring ◽  
Quality Improvements ◽  
Web Based ◽  
Donor Human Milk ◽  
Continuous Quality ◽  
Milk Bank ◽  
Before And After ◽  
Human Milk Bank ◽  
Operation Status

Abstract ObjectivesTo analyze the operation status and data over the last 8 years of operation of the first human milk bank (HMB) in East China.MethodsData related to the costs, donors, donation, pasteurization, and recipients were extracted from the web-based electronic monitoring system of the HMB for the period August 1, 2013 to July 31, 2021. ResultsOver the 8 years of operation, 1,555 qualified donors donated 7,396.5 L of qualified milk at a cost of ¥1.94 million, with the average cost per liter of donor human milk being ¥262.3. The donors were between 25 and 30 years of age, and the majority (80.1%) were primipara. All the donated milk was pasteurized and subjected to bacteriological tests before and after pasteurization: 95.4% passed the pre-pasteurization tests, and 96.3% passed the post-pasteurization tests. A total of 9,207 newborns received 5,775.2 L of pasteurized donor milk. The main reason for the prescription of donor human milk was preterm birth. As a result of continuous quality improvements, January 2016 witnessed a significant increase in the volume of qualified DHM and the number of qualified donors. However, in 2020, as a result of the restrictions related to the COVID-19 pandemic, the volume of qualified DHM and the number of qualified donors decreased. ConclusionsOver its 8 years of operation, our HMB has made steady quality improvements in its screening and information processes. Continuous quality improvement is on ongoing need, along with recruiting more qualified donors and collecting donor human milk for vulnerable newborns.

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