scholarly journals Quantification of the Content of Ten (10) Brands of Metronidazole Infusion Marketed in Abuja Metropolis by UV Spectroscopic Method

2020 ◽  
pp. 101-105
Author(s):  
Onavbavba Godspower ◽  
Alemede Vincent Odunayo

The proliferation of substandard drugs is a major public health challenge, especially in developing countries which lacks adequate resources to effectively monitor their prevalence. Currently, there are no reliable statistics on the level of incidence of fake drugs in Nigeria. The quality of medicines is an integral part in ensuring that pharmaceutical products are fit for their intended use, comply with requirements of marketing authorization and do not expose consumers to risks. For this to be achieved, there must be a system of quality assurance, which incorporates aspects including product development, manufacturing, distribution, and storage. This study aimed at quantifying the content of ten (10) brands of metronidazole infusion marketed in Abuja by UV-Spectroscopic method. Ten (10) brands of metronidazole were purchased in different pharmacies within the city of Abuja and were assayed using UV-Spectroscopic method as stated in British Pharmacopoeia 2017 edition. All the ten (10) brands of metronidazole that were assayed had a percentage content of 100.97% to 108.15%. From the study carried out, all the brands of metronidazole infusion complied with the content uniformity test as stated in the British Pharmacopeia.

2020 ◽  
Vol 8 (2) ◽  
pp. 14
Author(s):  
KPATA-KONAN Nazo Edith ◽  
YAO N’Zué Benjamin ◽  
COULIBALY Kalpy Julien ◽  
KONATÉ Ibrahim

This article looked at the quantity and storage time of attiéké produced and sold in the town of Daloa. It also examines the microbiological characteristics of attiéké-femme and attiéké-garba from this locality during storage. The study was carried out on the one hand through a field survey carried out on the producers and sellers. On the other hand, a sample was taken from 10 sellers of attiéké-garba and 10 sellers of attiéké-woman. The study found that the women producers sell 87% of their production in the city of Daloa and export 13%. In addition, attiéké can be kept for 2 days at the producers and beyond 2 days at the sellers before their stock runs out. Therefore, a weekly production of more than 200 kg for the majority of the producers is observed. Microbiological analyses showed high levels of germs (MAG: 6.106 CFU/g; Yeasts and moulds: 2.7.106 CFU/g) for attiéké-women and (2.106 CFU/g of GAM and 1.6.103 CFU/g of Yeasts and moulds) for attiéké-garba. Total coliforms and faecal coliforms were only found in attiéké-women. No salmonella was observed. In view of the results, it should be noted that female attiéké is the most contaminated type of attiéké.


Author(s):  
Sholichah Rohmani ◽  
Adi Yugatama ◽  
Ahmad Ainurofiq ◽  
Fea Prihapsara ◽  
Felicitas Lady

<pre>Atorvastatin is one of the first choice in the treatment of dyslipidemia associated with a decreased risk of cardiovascular disease. Drug patent expires in 2011. Currently in Indonesia circulated atorvastatin dosage tablet innovator , several trade names , and one generic. The purpose of this study was conducted to determine the quality of the preparation of atorvastatin market in Indonesia through tablet dosage uniformity test , so that the appropriate levels of drugs can provide the desired therapeutic effect.</pre><pre>Uniformity tablet dosage form of atorvastatin is done by measuring the uniformity of tablet weight, and content uniformity was done using ultraviolet spectrophotometry in methanol at the maximum wavelength of 246.2 nm and their validity was tested on the value of LOD (limit of detection), and LOQ (limit of quantitation). One- Way ANOVA analyzis was their also conducted.  </pre>The results showed that of the calculation data obtained , either in column A or column B that there is no deviation from the weight of the tablet , and based on the calculation of CV showed that all the tablets of atorvastatin in the market already qualified uniformity of weight as indicated by the value of CV &lt; 5 %, and the levels atorvastatin tablet generic and tablets under the trade name meets the standard requirements of a tablet that in the range 90.0 % - 110.0 % of the amount listed on the label


FLORESTA ◽  
2013 ◽  
Vol 43 (2) ◽  
pp. 181 ◽  
Author(s):  
Juliana Baladelli Ribeiro ◽  
Marília Borgo ◽  
Leila Teresinha Maranho

 A conservação de fragmentos florestais é extremamente necessária para garantir a manutenção da biodiversidade, além de assegurar o armazenamento de carbono contido na biomassa e nos solos. O município de Curitiba (PR, Brasil) possui 52 áreas protegidas municipais com remanescentes de Floresta Ombrófila Mista (FOM) em diferentes estágios de conservação, as quais contribuem para a manutenção da biodiversidade, melhoria da qualidade de vida dos moradores e também auxiliam na mitigação das mudanças climáticas, pois estocam grandes quantidades de carbono nos diversos componentes florestais. O presente estudo foi desenvolvido com o objetivo de avaliar a importância dos fragmentos florestais de Curitiba na manutenção dos estoques de carbono de forma associada à sua importância para a preservação da biodiversidade, o que pode servir de incentivo para o investimento público nessas áreas e de estímulo a outros municípios para a criação e manutenção de UCs. O estoque de carbono contido nos remanescentes florestais do município (1.159.259,60 t C) reforça a importância da conservação de remanescentes de vegetação nativa, ainda que em meio ao ambiente urbano.Palavras-chave: Carbono; desmatamento evitado; Floresta com Araucária; áreas verdes urbanas. AbstractProtected Areas in Curitiba, PR, Brazil, as carbon sinks.Conservation of forest’s fragments is extremely necessary to ensure maintenance of biodiversity and storage of carbon. There are currently 52 protected areas (PAs) in Curitiba municipality, located in Parana State – Brazil, with remnants of Araucaria Forest at different stages of conservation contributing to maintenance of biodiversity, improving quality of life of residents and also assisting in prevention of climate change as the aforementioned areas store large amounts of carbon in a range of forest components. In 2009, Curitiba conducted a research to estimate the carbon stock of forest fragments. The present research was carried out in order to evaluate the importance of these fragments in the maintenance of carbon stocks, associated to the preservation of biodiversity, which may be an incentive for public investment in these areas and encouragement to other municipalities for the creation and maintenance of PAs. Based on available information on the carbon contained in forest remnants of the city, it was identified that the total of those areas involves a stock of 1,159,259.60 t C, which reinforces the importance of maintaining native vegetation even in urban environment. Keywords: Carbon; deforestation prevention; Araucaria Forest; urban protected areas.


2019 ◽  
Vol 45 (4) ◽  
pp. 403-409
Author(s):  
Gabriela Rezende de Souza ◽  
André Geraldo Cornélio Ribeiro

The waste cooking oils (WCOs), when wrongly discarded, bring environmental damages, additionally to structural problems and financial losses if released in the sewage system. However, the correct management of this residue allows its reuse and recycling, representing economic gains, besides social and environmental benefits. There are several alternatives to recycling and reusing WCOs and the biodiesel production presents itself as one of the most important. Nevertheless, it is necessary to guarantee the residue quality in order to utilize its potential, as well as a coordinated management of WCO, promoting the correct processing and disposal of this waste. In this context, this article aims to propose an environmentally appropriate WCO onsite handling and collection in Lavras-MG, by evaluating the WCO management at three establishments in the city. The evaluation had taken into account the quantity of WCO generated, handling, storage and collection methods adopted, and the quality of the residue, by analyzing levels of acid, iodine and peroxide and saponification value. The results revealed the current management of the WCO, the actors involved in the management chain, the way the different frying and storage processes influence the WCO quality for reusing and recycling and possible alternatives to improve the management. The WCO management chain, composed of ACAMAR, G-Óleo, E1 and E2, is widespread and shows potential to transform the WCO into several other products, in addition to biodiesel and handmade soap. At long last to coordinate the correct WCO handling, collection, processing and disposal it is essential to guarantee the participation of the generators, collectors, and the government.


2021 ◽  
Vol 2 (1) ◽  
pp. 47-57
Author(s):  
F. Yusuf ◽  
◽  
S.J. Madu ◽  
A.O. Abdussalam ◽  
A.S. Ibrahim ◽  
...  

BACKGROUND: The proliferation of counterfeit, substandard and inferior quality drugs is a major challenge in low- middle income countries like Nigeria where drug regulation and law enforcement are constrained by limited resources. OBJECTIVES: The aim of the study was to assess the quality parameters of some brands of Omeprazole capsules marketed in Maiduguri Metropolis, Borno State, Nigeria. METHODS: The uniformity of weight, disintegration test, content uniformity and dissolution rate test were the official tests carried out using Pharmacopoeial methods. Organoleptic tests and other non-official tests were carried out. RESULTS: Ten brands of omeprazole capsules were assessed for purity using omeprazole sample as standard for comparison. All the ten brands tested passed the visual inspection, organoleptic tests, weight uniformity and disintegration tests. Three (3) brands (OMC 1, 4 and 6) out of the ten (10) brands passed the content uniformity test, while the other seven (7) brands were either below or above the acceptable Pharmacopoeial limit. For the dissolution test, only three (3) brands (OMC 1, 3 and 8) passed the test. CONCLUSION: The results therefore, indicated that some of the brands of the Omeprazole capsules marketed in Maiduguri Metropolis failed to comply with some Pharmacopoeial standards.


2020 ◽  
Vol 9 (8) ◽  
pp. e15985280
Author(s):  
Valdeci Junior Fonseca Pinheiro ◽  
Ivan Carlos da Costa Barbosa ◽  
Diego Fabrício Santa Rosa Cardoso ◽  
Rosa Maria Souza Santa Rosa ◽  
Luciana Pinheiro Santos ◽  
...  

Wheat is a crop rich in nutrients. In Brazil, about 130,000 properties produce the cereal, involving 800,000 people. Due to its rheological properties, that is, the extensibility capacity of this cereal stands out in the manufacture of breads, in addition to the increasing use of flour in the food industry. Thus, the use of some physical-chemical analysis to determine the quality of wheat flour according to the normative instruction from Agriculture, Livestock and Storage Ministry (MAPA) document nº 8/2005. Wheat flour samples of type 1 (A, B and C) were acquired in a supermarket located in the city of Belém / PA, posteriorly sent to the Centro de Tecnologia Agropecuária - CTA at the Universidade Federal Rural da Amazônia (UFRA), to determine granulometry, grease acid, protein, humidity and ashes. Regarding to granulometry analysis, samples A and C were above the tolerance values proposed by the Ministry of Agriculture and Livestock - MAPA. Grease acid and humidity were inside to MAPA tolerance standards for all samples. In ashes determining, the values showed that all three samples were out of the quality standard, in addition, about protein content, the samples were also characterized as out of type. Therefore, there is a need for better inspection by the responsible authorities, since cultivation conditions until the final quality control of the product.


Author(s):  
Mudasetia Hamid ◽  
Evy Rosalina Widyayanti

Yogyakarta is a city and the capital of Yogyakarta Special Region in Java, Indonesia. It is renowned as a center of tourism, education and culture. Yogyakarta is one of the foremost cultural centers of Java. This region is located at the foot of the active merapi vulcano. Yogyakarta is often called the main gateway to the Central Java as where it is geographically located. It stretches from Mount Merapi to the Indian Ocean. This province is one of the most densely populated areas of Indonesia. Yogyakarta is popular tourist destination in indonesia after Bali. These have attracted large number of visitors from across Indonesia and abroad to the city. This status makes Yogyakarta is one of the most heterogeneus cities in Indonesia. In edition, Yogyakarta has attracted large number of people to reside in this city for business. One of these comers is small entrepreneurs with their market munchies enterprise (specially a traditional snack trader). This business is one of famous business in Yogyakarta, we will find rows of pavement vendors selling market munchies. The students and tourists are their main target customers. Market munchies enterprise is part of small and medium enterprises SMEs as livelihood activities. SMEs has an important role in economic growth of Indonesia. Therefore, it is very important to develop and strengthen the micro enterprise empowerment. Micro enterprise empowerment is one of strategy to reduce the poverty rate in Indonesia. Major challenger in implement this program are that micro entrepreneurs are conventional and have satisfied with their revenue. It is very important to develop a comprehensive and sustainable micro enterprise empowerment which consist of strengthen the quality of human resources, maximize the government’s roles, empower the enterprise capital and strengthen the partnership and autonomous. Micro enterprise autonomy will contribute to the economic and investment climate. This will lead to establish an accountable enterprise both for the micro enterprise and customers which at the end will strengthen the development of the micro enterprise in Yogyakarta.Keyword: micro entreprise, human resources, government roles, capital, partnership and autonomous.


2014 ◽  
Vol 25 (3-4) ◽  
pp. 77-83
Author(s):  
S. L. Grabovska ◽  
L. O. Kolodochka

This article deals with the results of study of species content and basic peculiarities of beaked mites-Phytoseiidae in plant associations of one of the regional centers of Ukraine. The species composition and distribution of mites-Phytoseiidae (Parasitiformes, Phytoseiidae) in plantations of Brovary town of Kyiv region were determined. Fourteen species of 8 genera of phytoseiid mites were found. Index of their existing and relative biotope connection of each registered species to vegetation types and plant species were computed. The study was conducted according to the results of material treatment on the territory of the mentioned city from 25 species of plants (16 species of hardy-shrub and 9 of herbaceous vegetations). The studies of distribution of plant-living mites-Phytoseiidae were conducted separately for hardy-shrub and herbaceous plants). The collection of faunistic material was executed during the vegetation of periods of 2011 and 2013. Within the city the collection of the material was conducted with hardy-shrub plants and herbaceous type of vegetation along the streets, in parks and squares of Brovary city of Kyiv region, district center, one of the satellite-cities of Kiev, the capital of Ukraine. The study of species complexes characteristics of mites was conducted with usage of data calculated on the basis of frequency index (Is), degree of relative habitat confinedness (F) (Pesenko, 1982) and domination index Paliy-Kovnatski (Di) (Shitikov, 2003). Only on one species of plant (F=1) 6 species of mites-Phytoseiidae were found – T.сotoneastri on blue spruce, T. laurae – on common spruce, T. aceri – on ash-leaved maple, P. incognitus – on dog-rose, P. soleiger – on mulberry-tree, A. caudiglans – on sea-buckthorn. These species can be related to stenoecic. The mentioned species are stenotopic only in relation to the sample of plants from the plant associations of Brovary, as in other regions these species of mites can populate the other species of plants. The rest 8 species, being registered on two or more types of plants, are related to euryoecic. Among them there is a group of 6 species with “positive tendencies to population of plants”, owning the indicators of habitat confinedness 0<F<1: A. andersoni (0,92–0,96), A. rademacheri (0,85–0,96), N. herbarius (0,92–0,96), T. tiliarum (0,66–0,77), A. pirianykae (0,73–0,99), A. clavata (0,82–0,98). The rest species, E. finlandicus и K. aberrans, have the expanded range of indicators in relation to habitat confinedness (-0,71<F<0,55 и -0,16<F<0,88), that specifies on their ability to populate the big quality of species. E. finlandicus has the negative indicator of relative habitat confinedness in relation to the plants of herbaceous morphotype that serves confirmation of the ecological peculiarity of the species detected earlier. The data of relative habitat confinedness of mites to certain species of plants shows availability of stenoecic (T.сotoneastri, T. laurae, T. aceri, P. incognitus, P. soleiger, A. caudiglans) and euryoecic species (A. andersoni, A. rademacheri, N. herbarius, E. finlandicus, K. aberrans, T. tiliarum, A. pirianykae, A. clavata). 


2020 ◽  
Vol 4 (2) ◽  
pp. 95-110
Author(s):  
Buyung Syukron ◽  
Andi Thahir ◽  
Tin Amalia Fitri ◽  
Asep Rohman

The learning process in madrasas (Islamic-based elementary schools) is seen as being able to contribute to instilling values and norms in students following Islamic teachings. The issue of organizational culture and teacher performance also becomes a determining factor in creating a quality learning process. In this research, the aim is to determine: 1) the effect of organizational culture on the quality of the learn-ing process; 2) the effect of teacher performance on the quality of the learning process; and 3) the influ-ence of organizational culture on teacher performance. Respondents in this study were all class teachers from three madrasas as a sample representing all public madrasas in the city of Bandar Lampung, Indo-nesia. The results obtained indicate that the variables of organizational culture and the quality of the learning process have an influence, with R squared of 0.67 or 67%, which is classified as moderate. This shows that madrassas have implemented predetermined work culture values, namely: a) integrity, the harmony between correct thoughts, words, and deeds; b) professionalism, working in a disciplined, competent, and timely manner with the best results; c) innovation, perfecting existing and creating new and improved techniques and ideas; d) responsibility, working thoroughly and with thought for the con-sequences; and e) being exemplary, setting a good example for others.


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