scholarly journals STUDI LITERATUR EFEK MODIFIKASI GAYA HIDUP SECARA INTENSIF PADA PREDIABETES

2020 ◽  
Vol 7 (4) ◽  
Author(s):  
Serra Meilawati

Prediabetes adalah kondisi sebelum terjadinya diabetes mellitus tipe 2. Impaired Fasting Glucose (IFG) dan Impaired Glucose Tolerance (IGT) merupakan kondisi prediabetes. Prevalensi diabetes mellitus tipe 2 yang terus meningkat disebabkan karena setiap tahunnya 4-9% orang dengan prediabetes akan berkembang menjadi diabetes. IGT mempunyai risiko lebih tinggi untuk berkembang menjadi diabetes mellitus tipe 2. Sehingga upaya pencegahan agar tidak berkembangnya prediabetes menjadi diabetes mellitus tipe 2 menjadi sangat penting. Modifikasi gaya hidup secara intensif merupakan upaya yang dapat dilakukan pada prediabetes. Diabetes Prevention Program (DPP) di Amerika Serikat dan Finnish Diabetes Prevention Study (DPS) melakukan uji klinis yang menunjukkan bahwa modifikasi gaya hidup efektif dalam mengurangi atau menunda onset diabetes mellitus tipe 2 sebesar 4058% pada individu yang mempunyai risiko tinggi. Adapun modifikasi gaya hidup yang dapat dilakukan seperti, penurunan berat badan pada prediabetes dianjurkan sebesar 5-10% dari berat badan awal, perubahan pola makan dengan mengurangi konsumsi karbohidrat sederhana dan memperbanyak konsumsi serat, dan aktivitas fisik dilakukan selama 30-60 menit setiap hari. Modifikasi gaya hidup secara intensif pada prediabetes mempunyai efektivitas yang bagus.

2020 ◽  
Vol 103 (8) ◽  
pp. 829-836

It is well established that individuals who have prediabetes either impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) have high risk to develop diabetes. However, it is unclear whether the rate of progression to diabetes is different between these two categories. Lifestyle modification has been recommended for diabetes prevention in these high-risk groups. However, given the differences in their pathophysiology, it is possible that these subtypes of prediabetes condition may have different responses to lifestyle modification. The present review was to summarize the risk of progression to diabetes and the effectiveness of lifestyle intervention for diabetes prevention in individuals who have isolated IGT or isolated IFG or combined. The risk of progression to diabetes is highest in combined IFG and IGT subtype. Individuals who have isolated IFG by the American Diabetes Association criteria (100 to 125 mg/dl) has lower risk of progression to diabetes than those with World Health Organization criteria (110 to 125 mg/dl) and the latter has similar or higher risk of incident diabetes than those with isolated IGT. Lifestyle modification is most effective in individuals with IGT (with or without IFG) but is less effective in those with isolated IFG. In conclusion, The risk of progression to diabetes and the effectiveness of lifestyle intervention for diabetes prevention are disparate between prediabetes subtypes. Given the paucity of diabetes prevention data in individuals with isolated IFG, more studies dedicated to this subtype is required. Keywords: Impaired fasting glucose, Impaired glucose tolerance, Prediabetes, Type 2 diabetes, Lifestyle intervention, Diabetes prevention


Diabetes Care ◽  
2006 ◽  
Vol 29 (3) ◽  
pp. 709-711 ◽  
Author(s):  
L. Niskanen ◽  
D. E. Laaksonen ◽  
J. Lindstrom ◽  
J. G. Eriksson ◽  
S. Keinanen-Kiukaanniemi ◽  
...  

Author(s):  
Thanh Long Le ◽  
Trung Vinh Hoang

Objective: To evaluate the prevalence of newly diagnosed prediabetes, diabetes mellitus among the officers from Phuoc Long district of Binh Phuoc province. Subjects and methods: 268 personals communications service was examined the impaired fasting glucose (G0); impaired glucose tolerance (G2) anh HbA1c. Results: Prevalence of prediabetes, type 2 diabetes mellitus by G0, G2, HbA1c as follows 16,0%; 13,1%; 17,9% and 3,8%; 6,7%; 2,2%. Common prevalence of prediabetes in 26,9%; type 2 diabetes mellitus in 7,1%. Conclusion: Personal communications service from Phuoc Long district have percentage of prediabetes higher compared to type 2 diabetes mellitus which of prediabetes was diagnosed by HbA1c which takes up the highest percentage; diabetes mellitus was diagnosed by G2which takes up the highest percentage.


2020 ◽  
Author(s):  
Seyyed Saeed Moazzeni ◽  
Hamidreza Ghafelehbashi ◽  
Mitra Hasheminia ◽  
Donna Parizadeh ◽  
Arash Ghanbarian ◽  
...  

Abstract Background: Coronary heart disease (CHD) is one of the main causes of deaths. Alarmingly Iranian populations had a high rank of CHD worldwide. The current study aimed to assess the prevalence of CHD across different glycemic categories. Methods: This study was conducted on 7,718 Tehranian participants (Men=3427) aged ≥ 30 years from 2008 to 2011. They were categorized based on glycemic status. The prevalence of CHD was calculated in each group, separately. CHD was defined as hospital records adjudicated by an outcome committee. The association of different glycemic categories with CHD was calculated using multivariate logistic regression, compared with normal fasting glucose /normal glucose tolerance (NFG/NGT) group as reference. Results: The age-standardized prevalence of isolated impaired fasting glucose (iIFG), isolated impaired glucose tolerance (iIGT), both impaired fasting glucose and impaired glucose tolerance (IFG/IGT), newly diagnosed diabetes mellitus (NDM), and known diabetes mellitus (KDM) were 14.30% [95% confidence interval (CI): 13.50-15.09], 4.81% [4.32-5.29], 5.19% [4.71-5.67], 5.79% [5.29-6.28] and 7.72% [7.17-8.27], respectively. Among a total of 750 individuals diagnosed as cases of CHD (398 in men), 117 (15.6%), 453 (60.4%), and 317 (42.3%) had history of myocardial infarction (MI), cardiac procedure, and unstable angina, respectively. The age-standardized prevalence of CHD for Tehranian population was 7.71% [7.18-8.24] in total population, 8.62 [7.81-9.44] in men and 7.19 [6.46-7.93] in women. Moreover, among diabetic participants, the age-standardized prevalence of CHD were 13.10 [9.83-16.38] in men 10.67 [8.90-12.44] in women, respectively, which were significantly higher than corresponding values for NFG/NGT and prediabetic groups. Across 6 levels of glycemic status, CHD was associated with IFG/IGT [ odds ratio (OR) and 95% CI: 1.38 (1.01-1.89)], NDM [1.83 (1.40-2.41)], and KDM [2.83 (2.26-3.55)] groups, in the age and sex adjusted model. Furthermore, in the full-adjusted model, only NDM and KDM status remained to be associated with the presence of CHD by ORs of 1.40 (1.06-1.85) for NDM and 1.90 (1.50-2.41) for KDM. Conclusion: The high prevalence of CHD, especially among diabetic populations, necessitates urgent implementation of behavioral interventions among Tehranian population, according to evidence-based guidelines for the clinical management of diabetic patients.


2010 ◽  
Vol 28 (1) ◽  
pp. 36-42 ◽  
Author(s):  
P. Pajunen ◽  
M. Peltonen ◽  
J. G. Eriksson ◽  
P. Ilanne-Parikka ◽  
S. Aunola ◽  
...  

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