Factors Predicting Positive Axillary Lymph Nodes Metastasis in Primary Breast Cancer in Women

2012 ◽  
Vol 10 (2) ◽  
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Primary Breast Cancer ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Lymph Nodes Metastasis

Preoperative Staging of Large Primary Breast Cancer With [18F]Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Compared With Conventional Imaging Procedures

2008 ◽  
Vol 26 (29) ◽  
pp. 4746-4751 ◽  
Author(s):  
David Fuster ◽  
Joan Duch ◽  
Pilar Paredes ◽  
Martín Velasco ◽  
Montserrat Muñoz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Sensitivity And Specificity ◽  
Primary Breast Cancer ◽  
Distant Metastases ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Pet Ct ◽  
Large Primary

Purpose To evaluate the utility of positron emission tomography (PET) and [18F]fluorodeoxyglucose in the initial staging of large primary breast tumors. Patients and Methods This prospective study was approved by the ethics committee, and all patients gave their informed consent before enrollment. Sixty consecutive patients with large (> 3 cm) primary breast cancer diagnosed by clinical examination and breast magnetic resonance imaging (MRI) were entered onto the study. The mean age was 57 ± 13 years. Chest computed tomography (CT), liver ultrasonography, bone scan, and PET/CT were performed in all patients. All findings were histologically confirmed, and/or at least 1 year of follow-up was required. Correlation between parameters was calculated using Pearson's correlation coefficient. P < .05 was considered statistically significant. Results Primary tumor was identified by both PET/CT and MRI in all patients. Multifocal and/or multicentric tumors were found in 19 patients by MRI. Axillary lymph node metastases were found in 20 of 52 patients. Extra-axillary metastatic lymph nodes were also found in three patients. One patient showed an infiltrated lymph node in the contralateral axilla. The sensitivity and specificity for PET/CT to detect axillary lymph nodes metastases were 70% and 100%, respectively. PET/CT diagnosed all extra-axillary lymph nodes. The overall sensitivity and specificity of PET/CT in detecting distant metastases were 100% and 98%, respectively; whereas the sensitivity and specificity of conventional imaging were 60% and 83%, respectively. PET led to a change in the initial staging in 42% of patients. Conclusion PET/CT underestimates locoregional lymph node staging in large primary breast cancer patients. PET/CT is a valuable tool to discard unsuspected extra-axillary lymph nodes and distant metastases.

Evaluation of the expression levels of nm23-h1 mRNA in primary breast cancer, benign breast disease, axillary lymph nodes and normal breast tissue

Pathology ◽  
1994 ◽  
Vol 26 (4) ◽  
pp. 423-428 ◽  
Author(s):  
Rebecca J. Goodall ◽  
Hugh J.S. Dawkins ◽  
Peter D. Robbins ◽  
Erika Hähnel ◽  
Mohinder Sarna ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Primary Breast Cancer ◽  
Breast Tissue ◽  
Benign Breast Disease ◽  
Normal Breast Tissue ◽  
Breast Disease ◽  
Normal Breast ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph

Tuberculosis of axillary lymph nodes with primary breast cancer

Breast Cancer ◽  
2003 ◽  
Vol 10 (2) ◽  
pp. 175-178 ◽  
Author(s):  
Takaaki Fujii ◽  
Morihiko Kimura ◽  
Yasuhiro Yanagita ◽  
Tokihiro Koida ◽  
Hiroyuki Kuwano
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Primary Breast Cancer ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph

Serum microRNAs as a potential biomarker for evaluating axillary lymph nodes metastasis in breast cancer

2018 ◽  
Vol 92 ◽  
pp. S127
Author(s):  
S. Shiino ◽  
J. Matsuzaki ◽  
A. Shimomura ◽  
J. Kawauchi ◽  
S. Takizawa ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Lymph Nodes Metastasis ◽  
Potential Biomarker ◽  
Serum Micrornas
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