scholarly journals Study on Thyroid Hormone Status in Case of Female Infertility

2017 ◽  
Vol 8 (2) ◽  
pp. 117-120
Author(s):  
Nusrat Tasnim ◽  
Rokeya Begum

Background: Infertility is a global health issue causing great personal sufferings and distress. It is also matter of social injustice and inequality. Both hyperthyroidism and hypothyroidism causes menstrual disturbances secondary to anovulation. The degree of disturbances varies from abnormal sexual development through menstrual irregularity to infertility.Objective: To assess thyroid hormone status in female infertility.Method: A cross-sectional study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka during the period of July 2010 to June 2011. A total number of 250 female were included within the age limit of 20-40 years. Among them 125 subjects, healthy parous women were considered as control (group A) and 125 subjects, infertile women were considered as case (group B). The subjects were selected from Dhaka Medical College Hospital, infertility centre of BSMMU and BIRDEM, Dhaka. Data were collected in predesigned structured questionnaire form after taking consent. The study parameters are serumT3,T4 were measured in the Department of Nuclear Medicine, DMCH, Dhaka. For comparison between two groups, statistical analysis were done by Student's unpaired't' test. P<0.05 was considered as level of significance.Results: Serum T3 and T4 were significantly lower in group B than that of group A(P<0.001).Conclusion: From the results of the present study, it may be concluded that lower level of serum T3,T4 may be related with infertility.Anwer Khan Modern Medical College Journal Vol. 8, No. 2: Jul 2017, P 117-120

1970 ◽  
Vol 8 (2) ◽  
pp. 69-71 ◽  
Author(s):  
Segupta Kishwara ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Mahamuda Begum ◽  
Khandaker Abu Rayhan ◽  
Shamim Ara

Context: Preeclampsia is a relatively common pregnancy disorder that is related to the placenta and causes variable maternal and foetal problems. Alterations in placental weight are evident in moderate to severe maternal preeclampsia. Study design: Cross-sectional descriptive type. Place and period of study: Department of Anatomy, Dhaka Medical College, Dhaka from August 2005 to June 2006. Materials & Methods: 60 human placentae from Bangladeshi women were collected from the Department of Obstetrics & Gynaecology of Dhaka Medical College Hospital and Mitford Hospital, Dhaka of which 30 from normal uncomplicated pregnancies (control group or group A) and another 30 from pregnancies complicated by preeclampsia (preeclampsia group or group B), where the patients were normotensive previously. Results: The mean weight of the placenta was 406.90±72.64 gm in control group (group A) and 311.50±74.09 gm in preeclampsia group (group B) respectively. The mean difference in weight between two groups was statistically significant (P< 0.001). Conclusion: Placental weight was found reduced in maternal preeclampsia in comparison to that of normal pregnancy. Key words: weight of placenta; preeclampsia. DOI: 10.3329/bja.v8i2.7019Bangladesh Journal of Anatomy July 2010, Vol. 8 No. 2 pp. 69-71


2017 ◽  
Vol 25 (2) ◽  
pp. 82-86
Author(s):  
Afrina Begum ◽  
Tabassum Ghani ◽  
Subinoy Krishna Paul ◽  
Taufiqua Hussain ◽  
Noorjahan ◽  
...  

Introduction: Premature rupture of membrane or PROM means when membrane ruptures before the onset of labour at a gestational age less than 37 completed weeks. In Bangladesh, every year, around 28,000 women die due to complications of pregnancy and childbirth. Nonscientific intervention in PROM made at various levels intensify the pregnancy complications several times, thereby leading many more deaths of foetus and newborn. Aetiology of PROM is largely unknown. The possible causes are either reduction of membrane strength or an increase in intrauterine pressure or both. Proper diagnostic facilities, proper monitoring and standard protocol in the management can improve the maternal and fetal outcome.Aim and objective: The aim of the study was to observe the incidence, type and maternal and fetal outcome of PROM.Materials and Method: A prospective case control analytical study was carried out at Dhaka Medical College Hospital, Dhaka from May ‘2000 to December‘2000. Total 120 patients were selected for this study among them 60 patients as case (Group A) and 60 patients were taken as control (Group B). Both primi and multigravida with Pregnancy more than 28 weeks with intact membrane as control and spontaneous rupture of membrane taken as case. High- risk patients such as hypertensive disorder of pregnancy, APH, cardiac disease, previous H/O caesarean section were excluded from the study. After taking proper history, speculum examination, some diagnostic investigations were carried out. Findings were recorded in predesigned questionnaire and statistical analysis were done using computerized software SPSS for Windows. A P value < 0.05 was taken as significant.Results: In our study maternal complications were significantly higher in Group A patients (Chi-square test: X2 = 6.263, df= 1, P< 0.05). Number of premature babies in PROM patients (25%) was significantly higher than control group. Perinatal morbidity was found higher in PROM (36.66%) compared to control group (31.66%). Most common morbidity was neonatal jaundice in PROM patients (13.33%) compared to babies of control group (8.33%).Conclusion: This study focused on certain risk factors in relation to PROM which can be preventable and reduce incidence and improvement of maternal and fetal outcome.J Dhaka Medical College, Vol. 25, No.2, October, 2016, Page 82-86


2012 ◽  
Vol 18 (2) ◽  
pp. 138-144 ◽  
Author(s):  
Phub Tshering ◽  
Md. Abul Hasnat Joarder ◽  
M Alamgir Chowdhury ◽  
Kanu Lal Saha

Introduction: This study aimed to compare the clinico-pathological features of the tubotympanic and atticoantral variety of chronic suppurative otitis media (CSOM).Methods: This was a cross sectional observational study conducted in the department of Otolaryngology – Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU) and Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh. The study was done over a period of six months and a total of 60 cases were selected. In group A 30 cases of CSOM tubotympanic variety were included while in group B 30 cases of atticoantral variety of CSOM were selected. The two groups were compared with regard to their clinical presentations, the type and degree of hearing loss and their associated complications by taking a detailed history followed by clinical examination and doing the relevant investigations.Results: In group A, the patients presented with a profuse non smelly discharge. All had a central perforation and majority had mild conductive hearing loss. There were no associated complications. In group B, the aural discharge were foul smelling and scanty. The perforations were 66% in the attic while 33.3% had marginal perforations. The hearing loss was mainly conductive in nature but in group B it’s more severe in degree and also there were more associated severe to profound sensori-neural hearing loss. There were also associated extracranial and intracranial complications in group B patients.Conclusion: The atticoantral variety of CSOM is associated with a foul smelling scanty discharge with severe hearing loss and complications than the tubotympanic variety of CSOM. Therefore early detection becomes essential especially in the primary care setting for appropriate referral to higher centers for better management DOI:http://dx.doi.org/10.3329/bjo.v18i2.11991 Bangladesh J Otorhinolaryngol 2012; 18(2): 138-144


2016 ◽  
Vol 30 (2) ◽  
pp. 80-85 ◽  
Author(s):  
Sankar Kumar Basak ◽  
Kohinoor Begum ◽  
Maliha Rashid ◽  
Nahid Yasmin ◽  
Hasina Begum

Objective(s): To assess the association between the haematocrit value and severity of preeclampsia.Materials & Methods: This cross sectional study was conducted in the department of Obstetrics & Gynaecology of Dhaka Medical College Hospital, Dhaka during the period of January 2012 to December 2013. Total of 100 patients were studied and they were divided into two groups – group-A and group-B. Fifty preeclamptic patients were included in the group-A and 50 normal pregnant women were included in the group-B.Results: Majority of preeclamptic women (68%) and normal pregnant women (76%) were in the age group of 20-30 years with the mean ages of group-A and group-B subjects were 26.50±5.71 and 26.26±4.91 years respectively. Eighty six percent of group-A and 70% of group-B women were of lower socioeconomic status. Majority of the study subjects (74% of group-A and 80% of group-B) were housewife. More than half (54%) of the preeclamptic women were primigravid and 60% of normal pregnant women were multigravid. Among the preeclamptic subjects 16 (32%) had mild hypertension (DBP<110mmHg) and 34 (68%) had severe hypertension (DBP ? 110 mmHg). Out of 50 preeclamptic subjects 45 (90%) had severe proteinuria (+++) and only 5 (10%) had moderate (++) proteinuria.The mean haematocrit value of preeclamptic patients was 34.881±3.03 and that of normal pregnant women was 31.94±1.2. It was statistically significant (P value 0.001). The mean haematocrit value of normal pregnant, mild and severe preeclamptic women were 31.94±1.2, 33.31±2.57 and 35.62±2.95 respectively. It was also statistically significant (P value 0.001).Conclusion: This study shows that haematocrit value of preeclamptic patients is significantly higher compared to that of the normal pregnant women (P<0.05). There is a strong association of increasead haematocrit and preeclampsia.Bangladesh J Obstet Gynaecol, 2015; Vol. 30(2) : 80-85


2020 ◽  
Vol 23 (1) ◽  
pp. 11-18
Author(s):  
Md Anamul Haque ◽  
Md Kamrul Hasan Tarafder ◽  
ABM Luthful Kabir ◽  
Mohammad Harun Or Rashid ◽  
Dhiman Pramanik ◽  
...  

Objective: To find out association between Nasal polyposis and bronchial asthma. Methods: This was a cross sectional study which was carried out in the departments of Otolaryngology and Head-Neck surgery of Bangabondhu Sheikh Mujib Medical University and Dhaka Medical College Hospital during the period of February 2014 to July 2014. A Total 230 patients were selected according to selection criteria among which 30 subjects had nasal polyposis (designated as group A or cases) and 200 subjects had no nasal polyposis (designated as group B or control group). Results: In group (A), asthma was found in 30.0% cases. On the other hand, asthma was found in 2.5% of control group (B). The association of nasal polyposis with bronchial asthma was highly significant (p<.05). In both group 40.0% patients were within the 38-47 year’s age group. In case group, 80.0% patients had any sorts of allergic history on the other hand, only 15.0% patients had allergic history in control group. High eosinophil count was found 66.7% patients suffering from nasal polyposis with bronchial asthma and in comparison to patients suffering from nasal polyposis without bronchial asthma had high eosinophil count 42.85%. In group A High IgE level was found 66.7% patients suffering from nasal polyposis with bronchial asthma, on the other hand, 42.85% had IgE level among patients suffering from nasal polyposis without bronchial asthma. Conclusion: Patients with nasal polyposis and asthma are significantly associated. Both serum IgE and total circulating eosinophil count are significant associated with nasal polyposis and bronchial asthma. Bangladesh J Otorhinolaryngol; April 2017; 23(1): 11-18


2015 ◽  
Vol 23 (1) ◽  
pp. 68-72
Author(s):  
Shahanara Yeasmin ◽  
AFM Anwar Hossain ◽  
Tahmina Yeasmin ◽  
Md Ruhul Amin ◽  
Qazi Shamima Akhter ◽  
...  

Background: Thyroid diseases have a strong predominance in woman of childbearing age. Pregnancy may be associated with thyroid dysfunction. The aim of the present study was to assess the serum FT3, FT4 and TSH levels in pregnant women. Methods: This cross-sectional analytical study was done in the Department of Physiology of Dhaka Medical College, Dhaka, from July 2006 to June 2007. Total 50 apparently healthy women of low socioeconomic class, age ranged from 18-40 years were selected from the Outpatient Department of Urban Primary Health Care Project (UPHCP) at Mirpur, Dhaka. Out of them 30 pregnant women of different trimester were taken as study group (group A) and 20 age matched non pregnant women were taken as control (group B). Serum FT3, FT4 and TSH levels were parameters in both groups. Statistical analysis was done by the SPSS version 12.0. Results: The mean serum FT3 levels were 6.36±1.16 pmol/L and 6.381.36 pmol/L in group A (Study) and group B (control) respectively. The mean serum FT4 levels were 20.25±4.77 pmol/L and 19.39±8.17 pmol/L in group A (Study) and group B (control) respectively. The mean serum TSH levels were 0.96±0.96 mIu/L and 1.27±0.86 mIu/L in group A (Study) and group B (control) respectively. The difference was not significant (p>0.05) between group A and B. Conclusion: From the results obtained in the present study, it may be concluded that there is no change of serum FT3, FT4 and TSH level in pregnancy. DOI: http://dx.doi.org/10.3329/jdmc.v23i1.22697 J Dhaka Medical College, Vol. 23, No.1, April, 2014, Page 68-72


2020 ◽  
Vol 19 (1) ◽  
pp. 43-46
Author(s):  
Prasun Barua ◽  
Mohammed Kaisar Iqbal ◽  
Mahmudul Haque

Background: Burn is reported to cause significant alteration of haemocoagulativeparameters, but due to lack of proper understanding of burn coagulopathy, only theroutine coagulation tests are generally used, even though these provide limiteddiagnostic or prognostic information about burns and postburn complications. So,this study specifically aimed to characterize the changes in plasma FibrinDegradation Product (FDP) together with routine coagulative parameters and theirrelations with burn-severity. Materials and methods: This cross-sectional comparative study was carried out inthe Department of Biochemistry and Department of Burn and Plastic Surgery ofChattogram Medical College Hospital from January to December in 2014. 130subjects of 18 – 65 years enrolled in two groups by nonprobability consecutivesampling. Group-A consisted of 80 patients with minor, moderate and major burnsas per American Burn Association severity classification, whereas Group-B included50 age and sex-matched healthy subjects. Plasma FDP was estimated by immunoturbidimetricmethod in STA compact automated analyser. Bleeding Time (BT),Clotting Time (CT) and Prothrombin Time (PT) were also determined using standardmethods. Results: Burn patients had significantly higher mean FDP (10.13 ± 5.63 μg/ml) thancontrols (2.50 ± 1.56 μg/ml) which increased with increase in burn-severity (4.83,8.12 and 15.48 μg/ml in minor, moderate and major burns respectively). PlasmaFDP increased in 91.25% burn patients. While BT and CT were mostly unchanged, PTwas prolonged in 66.25% burn patients (Mean = 15 seconds) but that did not seemto correlate with burn-severity or with FDP.Conclusion: Plasma FDP increased significantly in burn patients showing better andconsistent correlation with burn-severity than routine coagulation parameters. Chatt Maa Shi Hosp Med Coll J; Vol.19 (1); January 2020; Page 43-46


2021 ◽  
Vol 8 (1) ◽  
pp. 39-43
Author(s):  
Selina Akhtar ◽  
Umme Hafsa Any ◽  
Sonia Fahmi

Background: Pre-eclampsia is the major cause of maternal and fetal mortality and morbidity. It affects approximately 5-8% of pregnant women. Objectives: The study was undertaken to find an association between Hemoglobin and preeclampsia. Methodology: This cross-sectional study was carried out in the Department of Physiology at Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh from July 2009 to June 2010. For this, 60 pregnant women of preeclampsia, age ranged from 18 to 39 years, more than 20th weeks of pregnancy were included in the study (group B). They were further divided into group B1 consisting of 30 mild preeclamptic women and group B2 consisting of 30 severe preeclamptic women. For comparison age and gestational period matched 30 normotensive pregnant women control (group A) were also studied. Both control (group A) and preeclamptic women were selected from Obstetric and Gynae in and out patient Department of BSMMU and Dhaka Medical College Hospital. Maternal hemoglobin concentration was measured by standard laboratory techniques. Result: In this study, hemoglobin levels were significantly higher in study (group B) than those of control (group A). Again Hemoglobin levels were higher in group B2 than B1, but not significant (P>0.05). Hemoglobin level was positively correlated with systolic and diastolic blood pressure but it was statistically non-significant (P>0.05). Conclusion: The study concluded that serum hemoglobin level is associated with preeclampsia. Journal of Current and Advance Medical Research, January 2021;8(1):39-43]


1970 ◽  
Vol 6 (1) ◽  
pp. 27-31
Author(s):  
Nasreen Sultana Lovely ◽  
Rokeya Begum ◽  
Qazi Shamima Akhter ◽  
Most. Sabinus Sultana ◽  
Salina Akhtar

Background: Thyroid dysfunction especially hypothyroidism is cardiovascular risk factor because of its association with elevated serum total and LDL cholesterol. Objective: To assess the association of thyroid hormone levels with IHD. Methods: This cross-sectional study was carried out on 50 IHD subjects aged 35 to 85 years (Group B), in the Department of Physiology, Dhaka Medical College, Dhaka from of July 2009 to June 2010. For comparison 50 age, sex, and BMI matched apparently healthy subjects (Group-A) were also studied. The study subjects were selected from coronary care unit (CCU) of Cardiology Department & OPD of Dhaka Medical College Hospital, Dhaka. Serum FT3, FT4 and TSH were assessed by radio-immuno assay. Statistical analysis was done by student’s unpaired ‘t’ test and chi-square test as applicable. Result: The mean ±SD of serum FT3 and FT4 were significantly lower and serum TSH was significantly higher in IHD patients than that of healthy subjects (p<0.05). Conclusion: Hypothyroidism occurs in patients suffering from IHD. Key words: Thyroid hormone; IHD. DOI: http://dx.doi.org/10.3329/jbsp.v6i1.8080 J Bangladesh Soc Physiol. 2011 June; 6(1): 27-31


2020 ◽  
Vol 21 (2) ◽  
pp. 105-110
Author(s):  
Md Shawkat Alam ◽  
Sudip Das Gupta ◽  
Hadi Zia Uddin Ahmed ◽  
Md Saruar Alam ◽  
Sharif Muhammod Wasimuddin

Objective: To compare the clean intermittent self-catheterization (CISC) with continuous indwelling catheterization (CIDC) in relieving acute urinary retention (AUR) due to benign enlargement of prostate (BEP). Materials and Methods :A total 60 patients attending in urology department of Dhaka Medical college hospital were included according to inclusion criteria ,Patients were randomized by lottery into two groups namely group –A and group –B for CISC and IDC drainage respectively . Thus total 60 patients 30 in each group completed study. Results : Most men can safely be managed as out-patients after AUR due to BPH. The degree of mucosal congestion and inflammation within the bladder was found to be lower in those using CISC and the bladder capacity in these patients was also found higher.Patients with an IDC had a high incidence of UTIs then that of patients with CISC. During the period of catheterization the incidence of UTI was 43.3% in group B in comparison to 40% in group A; before TURP 36% in group B in comparison to 10% incidence in group A.According to patient’s opinion CISC is better than IDC in the management of AUR. Experiencing bladder spasm, reporting blood in urine, management difficulties, incidence and severity of pain were less in CISC group, and the method of CISC was well accepted by patients as well as their family members. Conclusion: From the current study it may be suggested that CISC is better technique for management of AUR patient due to BPH than IDC. It can also be very helpful when surgery must be delayed or avoided due to any reasons in this group of patients. Bangladesh Journal of Urology, Vol. 21, No. 2, July 2018 p.105-110


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