Cough – A Curious Case

2017 ◽  
Vol 5 (2) ◽  
pp. 139-140
Author(s):  
Sanjith Saseedharan ◽  
Edwin Pathrose ◽  
AM Argikar
Keyword(s):  
Hemodynamic Monitoring ◽  
Rectus Sheath ◽  
Pulmonary Complications ◽  
Elderly Female ◽  
Life Threatening ◽  
Extra Pulmonary

Cough, as a symptom by default gets the focus of a physician towards the chest ruling out the causes could be of the same. However an incessant cough causing life threatening extra pulmonary complications is a rarity. We present a case of an elderly female who presented with a cough with expectoration but ended up requiring strict hemodynamic monitoring due to a rectus sheath hematoma.Bangladesh Crit Care J September 2017; 5(2): 139-140

Severe pulmonary complications in Japanese patients after bortezomib treatment for refractory multiple myeloma

Blood ◽  
2006 ◽  
Vol 107 (9) ◽  
pp. 3492-3494 ◽  
Author(s):  
Shigesaburo Miyakoshi ◽  
Masahiro Kami ◽  
Koichiro Yuji ◽  
Tomoko Matsumura ◽  
Masaaki Takatoku ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Adverse Effects ◽  
Gastrointestinal Symptoms ◽  
Japanese Patients ◽  
The United States ◽  
Underlying Disease ◽  
Pulmonary Complications ◽  
Bortezomib Treatment ◽  
Toranomon Hospital ◽  
Life Threatening

Bortezomib is a novel proteasome inhibitor with significant antimyeloma activity. Its frequent adverse effects are manageable, including gastrointestinal symptoms, peripheral neuropathy, and thrombocytopenia. Severe lung toxicity has not previously been reported. Between June 2004 and September 2005, 13 Japanese patients with multiple myeloma were treated with bortezomib in Toranomon Hospital, Juntendo University School of Medicine, and Jichi Medical School. Four of them developed severe pulmonary complications, and 2 died of respiratory failure without progression of underlying disease. To our knowledge, this is the first report on life-threatening pulmonary adverse effects after bortezomib therapy. Previous clinical studies on bortezomib, mostly in the United States and Europe, have shown low incidences of pulmonary adverse effects. Our study suggests that bortezomib can cause serious lung injury, and that its incidence might vary among different ethnicities. Clinicians need to be alert to the possibility.

scholarly journals Non-traumatic Tension Gastrothorax: A Potential Mimicker of Tension Pneumothorax

2021 ◽  
Vol 15 (8) ◽  
pp. 1-7
Author(s):  
Jonathan D. Pierce ◽  
Neal R. Shah ◽  
Ata A. Rahnemai-Azar ◽  
Amit Gupta
Keyword(s):  
Clinical Presentation ◽  
Tension Pneumothorax ◽  
Accurate Diagnosis ◽  
Imaging Features ◽  
Elderly Female ◽  
Hemodynamic Compromise ◽  
Mediastinal Shift ◽  
Increased Risk ◽  
Life Threatening ◽  
Tension Gastrothorax

Tension gastrothorax is a rare, life-threatening clinical condition caused by intrathoracic herniation of the stomach through a diaphragmatic defect which becomes increasingly distended over time. If not recognized promptly, this can rapidly progress to respiratory distress, mediastinal shift, and hemodynamic compromise. Initial clinical presentation and imaging findings closely mirror those of tension pneumothorax, confounding diagnosis and potentially leading to unnecessary interventions with increased risk of morbidity and mortality. Here, we present a case of an elderly female who presented with a non-traumatic tension gastrothorax and a review of key imaging features and strategies to aid in recognition and accurate diagnosis of this emergent clinical entity.

scholarly journals Acute portal vein thrombosis secondary to COVID-19: a case report

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Roham Borazjani ◽  
Seyed Reza Seraj ◽  
Mohammad Javad Fallahi ◽  
Zhila Rahmanian
Keyword(s):  
Abdominal Pain ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Acute Abdominal Pain ◽  
Anticoagulation Therapy ◽  
Pulmonary Complications ◽  
Case Presentation ◽  
Vein Thrombosis ◽  
Extra Pulmonary ◽  
Secondary Causes

Abstract Background COVID-19 pneumonia exhibits several extra-pulmonary complications. Case presentation A 23-year old, asthmatic male with coronavirus pneumonia developed with generalized, acute abdominal pain. Further evaluations revealed a mild ascites and portal vein thrombosis although the patient received proper anticoagulation therapy. Routine lab data regarding the secondary causes of portal vein thrombosis were normal. Conclusion We speculated that the underlying cause of portal vein thrombosis in our case was coronaviruses. Therefore, clinicians should always consider thrombosis and other hypercoagulable diseases in patients with COVID-19.

scholarly journals Botulinum toxin A for trismus in cephalic tetanus

1994 ◽  
Vol 52 (3) ◽  
pp. 410-413 ◽  
Author(s):  
Luiz Augusto F. Andrade ◽  
Sonia Maria D. Brucki
Keyword(s):  
Botulinum Toxin ◽  
Botulinum Toxin A ◽  
Pulmonary Complications ◽  
Toxin A ◽  
Clostridium Tetani ◽  
Considerable Difficulty ◽  
Respiratory Problems ◽  
Life Threatening ◽  
The Difference ◽  
Cephalic Tetanus

Cephalic tetanus is a localized form of tetanus. As in generalized forms , trismus is a prominent feature of the disease, leading to considerable difficulty in feeding, swallowing of the saliva and mouth hygiene. These difficulties often precede respiratory problems and aspiration bronchopneumonia is a frequent life-threatening complication. Muscle relaxants other than curare drugs may show a limited benefit for relieving trismus. Tetanospasmin, the tetanic neurotoxin, and botulinum toxin share many similarities, having a closely related chemical structure, an origin from related microorganisms (Clostridium tetani and Clostridium botulinum, respectively), and presumably, the same mechanisms of action in the neuron. The difference between the two lies in their peculiar neurospecificity, acting in different neurons. Injection of minute doses of botulinum toxin in the muscles involved in focal dystonias or other localized spastic disorders have proved to be very effective in these conditions. We describe the use of botulinum toxin A in the successful treatment of trismus in a patient suffering from cephalic tetanus. We believe that this form of treatment may be of value in lowering the risk of pulmonary complications in tetanic patients.

scholarly journals Rectus Sheath Haematoma Associated with Low Molecular Weight Heparin: A Case Series

2007 ◽  
Vol 89 (3) ◽  
pp. 309-312 ◽  
Author(s):  
J Donaldson ◽  
CH Knowles ◽  
SK Clark ◽  
I Renfrew ◽  
MD Lobo
Keyword(s):  
Molecular Weight ◽  
Low Molecular Weight Heparin ◽  
Case Series ◽  
Rectus Sheath ◽  
Low Molecular Weight ◽  
Recent Treatment ◽  
Life Threatening ◽  
Benign Nature ◽  
The Common

A report of three cases of spontaneous rectus sheath haematoma within a 1-month period in a single hospital. The common feature was the recent treatment with low molecular weight heparin. In contrast to the perceived benign nature of the classically-described haematoma, the cases described were life-threatening and required aggressive intervention.

scholarly journals Airflow limitation severity and post-operative pulmonary complications following extra-pulmonary surgery in COPD patients

Respirology ◽  
2017 ◽  
Vol 22 (5) ◽  
pp. 935-941 ◽  
Author(s):  
Beomsu Shin ◽  
Hyun Lee ◽  
Danbee Kang ◽  
Byeong-Ho Jeong ◽  
Hyung Koo Kang ◽  
...  
Keyword(s):  
Pulmonary Complications ◽  
Airflow Limitation ◽  
Pulmonary Surgery ◽  
Copd Patients ◽  
Extra Pulmonary

scholarly journals FLT-3 ITD Positive Acute Basophilic Leukemia with Rare Complex Karyotype Presenting with Acute Respiratory Failure: Case Report

2018 ◽  
Vol 26 (1) ◽  
pp. 87-94 ◽  
Author(s):  
Ion Antohe ◽  
Angela Dăscălescu ◽  
Cătălin Dănăilă ◽  
Mihaela Zlei ◽  
Iuliu Ivanov ◽  
...  
Keyword(s):  
Histamine Receptor ◽  
Pulmonary Complications ◽  
World Health ◽  
Hematological Neoplasms ◽  
Pulmonary Capillary ◽  
Leukemia Diagnosis ◽  
Life Threatening ◽  
Chemotherapy Initiation ◽  
Health Organization ◽  
Basophilic Leukemia

Abstract Background: Acute basophilic leukemia is a rare subtype of acute myeloid leukemia, as categorized by the 2008 World Health Organization classification of myeloid neoplasms. Acute basophilic leukemia diagnosis requires thorough morphological, cytochemical, immunophenotypic, molecular, and cytogenetic studies and exclusion of other hematological neoplasms associating basophilia. The disease course is defined by histamine driven, occasionally life-threatening respiratory, cardiovascular, cutaneous or digestive complications, as well as primary refractoriness to standard therapy. Clinical presentation: We herein report a case of a 63-year-old asthmatic female patient diagnosed with acute basophilic leukemia, associated with previously unpublished cytogenetic features and FLT-3 ITD mutation, pulmonary leukostasis and spontaneous pulmonary capillary leak syndrome, which worsened immediately following chemotherapy initiation. Respiratory complications were successfully managed, but recrudesced upon emergence of refractory disease and were ultimately fatal. We highlight the likelihood of pulmonary complications induced by basophil degranulation and tumor lysis in hypercellular acute basophilic leukemia and the potential benefit of histamine receptor blockade in this setting.

Haemodialysis

2018 ◽  
Author(s):  
Victor F. Seabra ◽  
Bertrand L. Jaber
Keyword(s):  
Staff Training ◽  
Visual Loss ◽  
Patient Monitoring ◽  
Pulmonary Complications ◽  
Safe Procedure ◽  
Successful Performance ◽  
Acute Complications ◽  
Life Threatening ◽  
Anaphylactoid Reactions

Since its first successful performance in 1945, haemodialysis has become a widely performed routine and safe procedure. However, despite significant improvements in the dialysis equipment, staff training, and patient monitoring, acute complications can occur during the therapy, ranging from mild to life-threatening. This chapter reviews selected acute complications that are encountered during or are directly related to the haemodialysis procedure, including cardiovascular, neuromuscular, haematological, and pulmonary complications, technical malfunctions, dialysis reactions (including anaphylactic and anaphylactoid reactions), and other complications such as post-dialysis fatigue, pruritus, priapism, and hearing and visual loss.

Osier Weber Rendu Syndrome: A Systemic Angiodysptasia

1995 ◽  
Vol 112 (5) ◽  
pp. P37-P37
Author(s):  
Robert I. White ◽  
Douglas A. Ross ◽  
William H. Saunders
Keyword(s):  
Family History ◽  
Pulmonary Complications ◽  
Educational Objectives ◽  
Life Threatening

Educational objectives: To screen patients with epistaxis for life-threatening brain and pulmonary complications associated with Osier Weber Rendu syndrome and to have further knowledge of genetics and family history necessary to advise and treat these patients.

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