scholarly journals Airflow limitation severity and post-operative pulmonary complications following extra-pulmonary surgery in COPD patients

Respirology ◽  
2017 ◽  
Vol 22 (5) ◽  
pp. 935-941 ◽  
Author(s):  
Beomsu Shin ◽  
Hyun Lee ◽  
Danbee Kang ◽  
Byeong-Ho Jeong ◽  
Hyung Koo Kang ◽  
...  
Keyword(s):  
Pulmonary Complications ◽  
Airflow Limitation ◽  
Pulmonary Surgery ◽  
Copd Patients ◽  
Extra Pulmonary

scholarly journals Exercise tolerance and dyspnea in patients with chronic obstructive pulmonary disease

2010 ◽  
Vol 67 (1) ◽  
pp. 36-41
Author(s):  
Ivan Cekerevac ◽  
Zorica Lazic ◽  
Ljiljana Novkovic ◽  
Marina Petrovic ◽  
Vojislav Cupurdija ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Function ◽  
Exercise Tolerance ◽  
Airflow Limitation ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Diffusion Capacity ◽  
Tolerance Level ◽  
Lung Hyperinflation ◽  
Copd Patients

Background/Aim. Peripheral muscle weakness and nutritional disorders, firstly loss of body weight, are common findings in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to analyse the impact of pulmonary function parameters, nutritional status and state of peripheral skeletal muscles on exercise tolerance and development of dyspnea in COPD patients. Methods. Thirty COPD patients in stable state of disease were analyzed. Standard pulmonary function tests, including spirometry, body pletysmography, and measurements of diffusion capacity were performed. The 6-minute walking distance test (6MWD) was done in order to assess exercise tolerance. Level of dyspnea was measured with Borg scale. In all patients midthigh muscle cross-sectional area (MTCSA) was measured by computerized tomography scan. Nutritional status of patients was estimated according to body mass index (BMI). Results. Statistically significant correlations were found between parameters of pulmonary function and exercise tolerance. Level of airflow limitation and lung hyperinflation had significant impact on development of dyspnea at rest and especially after exercise. Significant positive correlation was found between MTCSA and exercise tolerance. Patients with more severe airflow limitation, lung hyperinflation and reduced diffusion capacity had significantly lower MTCSA. Conclusion. Exercise tolerance in COPD patients depends on severity of bronchoobstruction, lung hyperinflation and MTCSA. Severity of bronchoobstruction and lung hyperinflation have significant impact on dyspnea level.

scholarly journals Predictors of co-morbidities in chronic obstructive pulmonary disease patients at a tertiary care centre in north India

2019 ◽  
Vol 7 (11) ◽  
pp. 4154
Author(s):  
Kaushlendra Pratap Narayan ◽  
S. K. Verma ◽  
Surya Kant ◽  
R. A. S. Kushwaha ◽  
Santosh Kumar ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Inflammatory Process ◽  
Tertiary Care ◽  
Airflow Limitation ◽  
Pulmonary Vasculature ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Co Morbidity

Background: Chronic obstructive pulmonary disease (COPD) is a common preventable and treatable disease that is characterised by persistent respiratory symptoms and airflow limitation. COPD is characterised by an intense inflammatory process in the airways, parenchyma, and pulmonary vasculature. It is possible in some cases that the inflammatory process may overflow into the systemic circulation, promoting a generalised inflammatory reaction. Patient with COPD often have concomitant chronic illness (co-morbidities). The aim of this study is to know the pattern of co-morbidities in COPD patients.Methods: This study was a cross sectional observational study conducted on 172 COPD patients (IPD and OPD) diagnosed on the basis of GOLD guideline 2017. Co morbidities were diagnosed as per standard defined criteria laid down in the respective guidelines.Results: 55.3% of the patients with COPD had co morbidities. 18/88(20.5%) patients presented with multiple co-morbidities. 49/88, 55.7% COPD patients were affected with cardiac (either only cardiac or had multiple organs affected besides cardiac), the commonest co-morbidity. Amongst cardiac, hypertension and congestive heart failure (CHF) was the commonest (n=19/49, 38.8% each) followed by CAD/CSA/IWMI/IHD/AF. Others were metabolic (n=14/88, 15.9%), GERD (n=13/88, 14.8%), Depression (n=11/88, 12.5%). Less prevalent co-morbidities were Osteoporosis (n=8/88, 9.1%), Lung cancer (n=6/88, 6.8%), Bronchiectasis (n=5/88, 5.6%) and OSA (n=3/88, 3.4%).Conclusions: Urban indwelling, advancing age and duration of illness, presentation with low mood, loss of pleasure/ interest, appetite disturbances and heart burn with relief on taking proton pump inhibitor can be predictors of co-morbidities in COPD patients. Chance of finding co-morbidities may be multifactorial. Thus, it is important to look out for co morbidities in each and every COPD patients.

scholarly journals Pulmonary complications of predominantly antibody immunodeficiencies in a tertiary lung center

2018 ◽  
Vol 11 (1) ◽  
pp. 1-7
Author(s):  
Seyed Alireza Mahdaviani ◽  
Sepideh Darougar ◽  
Davood Mansouri ◽  
Sabereh Tashayoie-Nejad ◽  
Mahshid Movahedi ◽  
...  
Keyword(s):  
Respiratory Infections ◽  
Diagnostic Delay ◽  
Clinical Manifestations ◽  
Pulmonary Complications ◽  
Age At Diagnosis ◽  
Airflow Limitation ◽  
Recurrent Pneumonia ◽  
Timely Diagnosis ◽  
Improve Life Expectancy ◽  
The Mean

Background and aims Respiratory infections are expressed very soon in the life in humoral immunodeficiencies and often lead to chronic irreversible complications such as bronchiectasis and chronic airflow limitation. This study was conducted to evaluate the pulmonary complications of predominantly antibody immunodeficiencies to show the benefits of timely diagnosis and appropriate therapy. Patients and methods The information of 48 patients involved with a type of predominantly antibody immunodeficiencies, including sex, type of primary immunodeficiency, age at the onset of symptoms, age at diagnosis, recurrent infections, respiratory symptoms, and pulmonary radiological and functional abnormalities were recorded and analyzed. Results In 48 patients evaluated, the mean age at diagnosis was 25.63 years. The mean diagnostic delay was estimated to be 13.62 years. The most recurring clinical manifestations, sinusitis (69.6%), otitis (43.5%), and recurrent pneumonia were the cause of frequent admissions in 68.8% of these patients. Bronchiectasis was frequently found (58.3%) in these patients mostly involving the middle and lower lobes (48.8% and 41.5%, respectively). Conclusions Respiratory complications, infectious or non-infectious, determine the prognosis of the disease in patients with predominantly antibody immunodeficiencies. Timely diagnosis and appropriate management may improve life expectancy and the quality of life in these patients.

scholarly journals Acute portal vein thrombosis secondary to COVID-19: a case report

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Roham Borazjani ◽  
Seyed Reza Seraj ◽  
Mohammad Javad Fallahi ◽  
Zhila Rahmanian
Keyword(s):  
Abdominal Pain ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Acute Abdominal Pain ◽  
Anticoagulation Therapy ◽  
Pulmonary Complications ◽  
Case Presentation ◽  
Vein Thrombosis ◽  
Extra Pulmonary ◽  
Secondary Causes

Abstract Background COVID-19 pneumonia exhibits several extra-pulmonary complications. Case presentation A 23-year old, asthmatic male with coronavirus pneumonia developed with generalized, acute abdominal pain. Further evaluations revealed a mild ascites and portal vein thrombosis although the patient received proper anticoagulation therapy. Routine lab data regarding the secondary causes of portal vein thrombosis were normal. Conclusion We speculated that the underlying cause of portal vein thrombosis in our case was coronaviruses. Therefore, clinicians should always consider thrombosis and other hypercoagulable diseases in patients with COVID-19.

Cough – A Curious Case

2017 ◽  
Vol 5 (2) ◽  
pp. 139-140
Author(s):  
Sanjith Saseedharan ◽  
Edwin Pathrose ◽  
AM Argikar
Keyword(s):  
Hemodynamic Monitoring ◽  
Rectus Sheath ◽  
Pulmonary Complications ◽  
Elderly Female ◽  
Life Threatening ◽  
Extra Pulmonary

Cough, as a symptom by default gets the focus of a physician towards the chest ruling out the causes could be of the same. However an incessant cough causing life threatening extra pulmonary complications is a rarity. We present a case of an elderly female who presented with a cough with expectoration but ended up requiring strict hemodynamic monitoring due to a rectus sheath hematoma.Bangladesh Crit Care J September 2017; 5(2): 139-140

scholarly journals Impaired Hemorheology in Exacerbations of COPD

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Erhan Ugurlu ◽  
Emine Kilic-Toprak ◽  
Ilknur Can ◽  
Ozgen Kilic-Erkek ◽  
Goksel Altinisik ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Chronic Obstructive Lung Disease ◽  
Airflow Limitation ◽  
Erythrocyte Aggregation ◽  
Treatment Modalities ◽  
Patient Treatment ◽  
Rheological Parameters ◽  
Chronic Obstructive ◽  
Copd Patients ◽  
Rbc Deformability

Background. Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation. Cardiovascular-related comorbidities are established to contribute to morbidity and mortality especially during exacerbations. The aim of the current study was to determine alterations in hemorheology (erythrocyte aggregation, deformability) in newly diagnosed COPD patients and their response to medical treatment and to compare with values of COPD patients with exacerbations.Materials and Methods. The study comprised 13 COPD patients, 12 controls, and 16 COPD patients with exacerbations. The severity of COPD was determined according toGlobal Initiative for Chronic Obstructive Lung Diseaseguidelines. Red blood cell (RBC) deformability and aggregation were measured by an ektacytometer.Results. RBC deformability of COPD patients with exacerbations was decreased compared to the other groups. Erythrocyte aggregation and plasma fibrinogen of COPD patients determined during exacerbations were higher than control.Conclusion. Decreased RBC deformability and increased aggregation associated with exacerbations of COPD may serve as unfavorable mechanisms to worsen oxygenation and thus clinical symptoms of the patient. Treatment modalities that modify rheological parameters might be beneficial.

scholarly journals The systemic nature of mustard lung: Comparison with COPD patients

2017 ◽  
Vol 10 (3) ◽  
pp. 114-127 ◽  
Author(s):  
Alireza Shahriary ◽  
Mostafa Ghanei ◽  
Hossein Rahmani
Keyword(s):  
Clinical Symptoms ◽  
Airway Remodeling ◽  
Serum Levels ◽  
Nuclear Factor Κb ◽  
Chemical Warfare Agent ◽  
Pulmonary Complications ◽  
Chronic Obstructive ◽  
Necrosis Factor Alpha ◽  
Copd Patients ◽  
Systemic Nature

AbstractSulphur mustard (SM) is a powerful blister-causing alkylating chemical warfare agent used by Iraqi forces against Iran. One of the known complications of mustard gas inhalation is mustard lung which is discussed as a phenotype of chronic obstructive pulmonary disease (COPD). In this complication, there are clinical symptoms close to COPD with common etiologies, such as in smokers. Based on information gradually obtained by conducting the studies on mustard lung patients, systemic symptoms along with pulmonary disorders have attracted the attention of researchers. Changes in serum levels of inflammatory markers, such as C-reactive protein (CRP), tumor necrosis factor alpha (TNF-α), nuclear factor κB (NF-κB), matrix metalloproteinases (MMPs), interleukin (IL), chemokines, selectins, immunoglobulins, and signs of imbalance in oxidant-antioxidant system at serum level, present the systemic changes in these patients. In addition to these, reports of extra-pulmonary complications, such as osteoporosis and cardiovascular disease are also presented. In this study, the chance of developing the systemic nature of this lung disease have been followed on using the comparative study of changes in the mentioned markers in mustard lung and COPD patients at stable phases and the mechanisms of pathogenesis and phenomena, such as airway remodeling in these patients.

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