Correlation between FNAC and Histopathology in the Diagnosis of Thyroid Lesions

2021 ◽  
Vol 27 (1) ◽  
pp. 81-85
Author(s):  
Md Nazmul Haque ◽  
Mahmudul Amin Sakik ◽  
Mohammad Ashequr Rahman Bhuiyan ◽  
Moshammat Fatima Akhter ◽  
Saif Rahman Khan ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Accurate Method ◽  
Needle Aspiration ◽  
Female Ratio ◽  
Male Female Ratio ◽  
Review Study ◽  
Needle Aspiration Cytology ◽  
Female Male Female ◽  
Record Review ◽  
Thyroid Lesions

Objective: To observe the correlation between fine needle aspiration cytology (FNAC) and Histopathology in the diagnosis of thyroid lesions. Methods:It was a Retrospective record review study .One hundred four (104) Patients with enlarged thyroid gland of both sexes were selected from admitted patients of National institute of ENT, Tejgaon, Dhaka, Duration was from January 2017 to December 2018. Every patients had preoperative FNAC & postoperative histopathology report of thyroid lesions. Results: FNACdiagnosis of thyroid lesions were correlated with histopathology diagnosis. Out of 104 patients 26 were male 78 were female. Male-Female ratio were 1:3.out of 104 patients most Patients were 31 to 40 years of ageGroup.out of 104 cases of FNAC 9 cases were false Cyto-diagnosis. Overall accuracy rate was 91.35%. Conclusion: FNAC is a reliable, safe and relatively accurate method as apreoperative evaluationin thyroid gland swelling before surgery. FNAC has more accuracy in detecting thyroid gland malignancy and therefore it is a reliable diagnostic test for evaluation of thyroid swelling. Bangladesh J Otorhinolaryngol; April 2021; 27(1): 81-85

scholarly journals Diagnostic outcome of fine needle aspiration cytology in 400 cases of head and neck masses in tertiary care center

2019 ◽  
Vol 5 (3) ◽  
pp. 665
Author(s):  
Alpesh V. Patel ◽  
Nehal R. Patel ◽  
Payal R. Vadher ◽  
Manali B. Kakadia
Keyword(s):  
Head And Neck ◽  
Care Center ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Female Ratio ◽  
Neck Masses ◽  
Male Female Ratio ◽  
Needle Aspiration Cytology ◽  
Head And Neck Masses ◽  
Thyroid Lesions

<p class="abstract"><strong>Background:</strong> The objective of the study was to identify various lesions of neck swellings and to study their distributions according<strong> </strong>to age, sex and site and to find out distribution of malignant, inflammatory and infective lesions in neck swellings.</p><p class="abstract"><strong>Methods:</strong> The prospective study was conducted in the department of ENT, SCL General<strong> </strong>Hospital, NHL MMC, Saraspur, Ahmedabad from July 2014 to July 2016. All indoor and outdoor 400 patients of SCL hospital presenting with palpable head and neck swellings were referred to the cytology section at SCL hospital for FNAC and included in present study.  </p><p class="abstract"><strong>Results:</strong> In our study out of 400 cases, lymph nodes constituted 276 cases with female<strong> </strong>preponderance. Among the inflammatory lesions, commonest lesion was tuberculosis which comprised of 147 cases followed by 64 cases of reactive lymphadenitis. In thyroid lesions the male: female ratio was 1:18, with maximum incidence in age group of 20-50 years. Total 95 cases were observed, out of which benign thyroid lesions (Bethesda grade II) were most common (92.63%). Salivary gland comprised of 11 cases, Out of 10 benign neoplastic lesions, 9 cases of pleomorphic adenoma and 1 cases of Warthin’s tumor were found.</p><p class="abstract"><strong>Conclusions:</strong> FNAC is a very simple and expeditious procedure which can be carried out without much<strong> </strong>problem. It reduces the necessities to perform excisions biopsy in many cases. Thus, FNAC can be recommended as a first line of investigation in the diagnosis of neck swellings and can be adopted as an outpatient procedure, thus reducing the cost and time of hospitalization.</p>

scholarly journals Clinicopathological features of pilomatricoma cases: Analysis of 21 cases

2014 ◽  
Vol 4 (7) ◽  
pp. 530-533
Author(s):  
D Ghartimagar ◽  
A Ghosh ◽  
K Gautam ◽  
S Thapa ◽  
SR Shrestha ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Needle Aspiration ◽  
Common Finding ◽  
Clinical Impression ◽  
Aspiration Cytology ◽  
Female Ratio ◽  
Male Female Ratio ◽  
Needle Aspiration Cytology ◽  
Age Range ◽  
Slow Growing

Background: Pilomatricoma is a slow-growing, asymptomatic tumour originating from outer sheath cells of hair follicle. In this study, we describe the clinical presentation and histopathological features of pilomatricoma. Materials and Methods: This was a hospital based retrospective study carried out in all patients who were diagnosed as pilomatricoma over a period of January 2001 to December 2013. The study was done in department of pathology, Manipal Teaching Hospital, Nepal. Results: A total of 21 cases of pilomatricoma were reported with age range of 9-53 years (mean age 23.7) and male female ratio of 1:1.1. The most common site of occurrence was neck and preauricular region. The size of the tumour ranged from 0.3 to 4.7cm with a mean of 1.2cm. Multiple occurrences were seen in 3 patients and ossifying pilomarticoma was seen in 4 cases. Conclusion: Pilomatricoma is a benign skin neoplasm of hair follicle matrix cells. Calcification is a common finding while dystrophic ossification also can occur in the tumour. Histopathology gives the definite diagnosis as fine needle aspiration cytology and clinical impression may be misleading. DOI: http://dx.doi.org/10.3126/jpn.v4i7.10293 Journal of Pathology of Nepal (2014) Vol. 4, 530-533

scholarly journals Accuracy Of Fine Needle Aspiration Cytology (FNAC) In The Diagnosis Of Thyroid Swellings

2013 ◽  
Vol 18 (2) ◽  
pp. 47-51 ◽  
Author(s):  
Md Alamgir Hossain Sikder ◽  
AZM Mahfuzur Rahman ◽  
Md Abul Khair
Keyword(s):  
Thyroid Gland ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Histopathological Diagnosis ◽  
Aspiration Cytology ◽  
Female Ratio ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Objective: To evaluate the accuracy of fine needle aspiration cytology (FNAC) in comparison to paraffin section in thyroid swelling. Study design: Cross sectional study. Place and duration of study: Department of Surgery, Bangabandhu Sheikh Mujib Medical University from July 2009 to June 2011. Patient and method: One hundred patients with enlarged thyroid gland of both sexes were selected from admitted patient of Surgery department. All patients had preoperative FNAC, performed by pathologist at the Histopathology department and postoperative specimen were also examined and histopathological diagnosis were made. All FNAC diagnosis were correlated with the histopathological diagnosis. Results: Out of 100 patients 23 were male and 77 were female, male-female ratio 1: 3.3. In FNAC 76 patients were diagnosed as benign lesion of which 8 were later diagnosed as malignant on histopathological examination (68 were true negative 8 were false negative). 22 cases were diagnosed as malignant, both on FNAC and histopathological examination. Only 2 cases were diagnosed as follicular neoplasm on FNAC but on histopathological examination diagnosed as follicular carcinoma (22 cases were true positive) in this study. Overall sensitivity of FNAC were 68.75%, specificity 100.00% and accuracy 90%; PPV=100% & NPV=87.18% Conclusion: FNAC is a reliable, safe and accurate method as a preoperative evaluation in thyroid gland swelling before surgery. FNAC has more accuracy and specificity in detecting thyroid gland malignancy and therefore it is a reliable diagnostic test for evaluating thyroid swellings. DOI: http://dx.doi.org/10.3329/jdnmch.v18i2.16023 J. Dhaka National Med. Coll. Hos. 2012; 18 (02): 47-51

scholarly journals Role of FNAC in evaluation of Parotid Gland Swelling

2019 ◽  
Vol 20 (1) ◽  
pp. 7-12
Author(s):  
Krisna Rani Majumder ◽  
Syed Serajul Karim ◽  
Md Monjurul Alam ◽  
Rajan Karmakar ◽  
Abu Taher Md Ashaduzzaman
Keyword(s):  
Parotid Gland ◽  
Benign Neoplasm ◽  
Needle Aspiration ◽  
Low Grade ◽  
Female Ratio ◽  
Small Series ◽  
Parotid Neoplasm ◽  
Male Female Ratio ◽  
Histopathology Finding ◽  
Needle Aspiration Cytology

Objectives: To find out the histological types of parotid neoplasm and to correlate thefindings of FNAC and final histological report in parotid gland neoplasm. Methods: A total 30 cases were studied from the inpatient departments of General Surgeryand Otolaryngology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka sinceJuly, 2011 to April, 2013. Fine Needle Aspiration Cytology (FNAC) was done in all cases andcompared with histopathology finding of postoperative specimen. Result: Regarding sex distribution benign neoplasm in female 13 (56.52%) and in male10(43.47%). As to the malignant parotid neoplasm in female 4(57.14%) and in male3(42.85%). All parotid neoplasm male: female ratio 1:1.3. Two cases involved in deep lobeof parotid & presented with inward and forward bulging of tonsil and pillars. Three cases ofwarthin'stumour only presented with swelling in the tail of parotid gland. In this series outof 30 cases of parotid neoplasm 23 (76.66%) cases were benign and rest 07 (23.33%)were malignant. Pleomorphic adenoma was the most common benign neoplasm 20(66.66%). Mucoepidermoid Carcinoma was most common malignancy 3 (10%) followed byadenoid cystic carcinoma 2 (6.66%). Out of 7, 3 were stage 3(42.85%) and 3 were stage4(42.85%). In histological grading 3 were low grade (42.85%) and 4 were high grade(57.14%). All the patient werepartotidectomy. Few were treated by radical parotidectomyplus radiotherapy. Conclusion: Though it is a small series to comment on the whole spectrum of the parotidgland neoplasm in Bangladesh, yet an idea about the frequency of disease can be establishedbut actual incidence in Bangladesh as a whole can not be ascertained from thisstudy. Journal of Surgical Sciences (2016) Vol. 20 (1) : 7-12

scholarly journals A Clinical Study on Salivary Gland Tumours in a Tertiary Health Care Setup

2020 ◽  
Vol 7 (49) ◽  
pp. 2918-2922
Author(s):  
Sreekanth Kotagiri ◽  
Ajay Chanakya Vallabhaneni ◽  
Sumanth Prasad Mandava ◽  
Manikanta Chowdary ◽  
Tarun Chowdary Gogineni ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Surgical Oncology ◽  
Needle Aspiration ◽  
Female Ratio ◽  
Salivary Gland Tumours ◽  
Modes Of Presentation ◽  
Male Female Ratio ◽  
Needle Aspiration Cytology ◽  
A Prospective Study

BACKGROUND Salivary gland (SG) neoplasms are rare, constitute of 3 - 4 % of head and neck tumours. 70 - 80 % of SG neoplasms occur in parotid gland. These are unique in the way they present, generally slow growing. A study was conducted to analyse various modes of presentation of SG tumours and to review the role of FNAC (Fine Needle Aspiration Cytology) in the diagnosis of SG tumours. METHODS This was a prospective study, conducted in the department of surgical oncology, October 2016 to July 2018. Individuals aged >18 years, came with swelling of the SGs were considered. Swellings that were not neoplasms, the individuals with inflammatory or infections of SGs, autoimmune diseases were excluded. Statistical analysis were performed by SPSS software version-21 and MS excel 2013. RESULTS Out of 40 participants, male female ratio was 2.07. The age was ranged between 31 – 70 years, maximum (80 %) members were in 41 – 60 group. Parotid gland was the most commonly followed by submandibular gland (20 %). Swelling alone was observed in 82.5 % (33) cases, two cases (5 %) presented with swelling along with pain with facial nerve involvement. CONCLUSIONS SG tumours occur in 4th to 6th decade, common among men. Parotid gland is most frequently involved, most often benign. FNAC had good accuracy in diagnosis and surgery is the main modality of treatment. KEYWORDS Salivary Gland, Tumour, Neoplasms, FNAC

scholarly journals CYTODIAGNOSIS OF HEPATIC LESIONS AND THEIR ASSOCIATION WITH SERUM ALPHA FETOPROTEIN LEVELS

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Sehgal Tamanna ◽  
Kusum Anuradha ◽  
Ahuja Vivek
Keyword(s):  
Tumor Marker ◽  
Needle Aspiration ◽  
Alpha Fetoprotein ◽  
Liver Lesions ◽  
Female Ratio ◽  
Male Female Ratio ◽  
Diagnostic Role ◽  
Serum Alpha Fetoprotein ◽  
Needle Aspiration Cytology ◽  
Hepatic Lesions

Background: Liver is a common organ for lodgement of various infections and metastasis from other parts of body. Fine needle aspiration cytology (FNAC) plays a major decisive diagnostic role and combined with USG diagnostic accuracy is 90-95% minimizing the need of biopsy. An increased in serum AFP concentration has been observed in Hepatocellular Carcinoma (HCC) and is an important serum tumor marker. Methods: The present study was done, with the aim of studying the cytomorphological features of hepatic lesions and their association with serum Alpha Fetoprotein (AFP) levels. Study was conducted on 56 patients who underwent USG guided FNAC for diagnosis of liver lesions. Cytomorphological pattern of liver lesions were studied and serum AFP levels of the same cases were measured. Results: Maximum number of cases was in age group of 61-70 years. Male: Female ratio was 1.4:1. 82.1% cases were malignant. Most common malignancy was Metastatic deposits of Adenocarcinoma (MDA). HCC was diagnosed in 5.4% cases. Serum AFP levels in HCC were 459.93 ± 41.69 ng/mL.15.4 % of the cases of MDA and 8.3% of the cases of Metastatic deposits of Poorly Differentiated Carcinoma (MDPDC) showed raised serum AFP levels. Association between cytodiagnosis and serum AFP range was statistically significant. Sensitivity=100%, specificity=81.4%, PPV=27.3% and NPV= 100% were obtained when serum AFP was used to differentiate metastatic lesions with HCC taking < 8.5ng/mL as cut off. Conclusion: USG guided FNAC of the liver is a rapid, reliable and economical screening test. Serum AFP has been the most widely used tumor marker for diagnosing HCC but raised levels are also seen in other hepatic lesions decreasing its specificity. Keywords: Liver, FNAC, Serum Alpha fetoprotein levels

scholarly journals Cytological Profile of Thyroid Lesions and it's Correlation with Clinical and Ultrasonography Findings

2016 ◽  
Vol 3 (1) ◽  
pp. 28 ◽  
Author(s):  
Ujwala S. Chavan ◽  
Archana Patil ◽  
Suresh V. Mahajan
Keyword(s):  
Thyroid Gland ◽  
Clinical Features ◽  
Needle Aspiration ◽  
Endocrine Gland ◽  
Aspiration Cytology ◽  
Diagnostic Modality ◽  
Proper Diagnosis ◽  
To Come ◽  
Needle Aspiration Cytology ◽  
Thyroid Lesions

<strong>Background:</strong> Thyroid gland is the first endocrine gland to develop, largest of all endocrine glands. Superficial location of thyroid gland allows evaluation of thyroid lesions by FNAC (fine needle aspiration cytology). <strong>Aims and Objective:</strong> To study cytological profile of thyroid lesions and correlate the results with Ultrasonography findings and clinical features. <strong>Material and Methods:</strong> This prospective study was carried out on 138 patients who came to the department from period of May 2012 to December 2014. Out of these 138 patients USG was carried out in 115 patients. FNAC of patients was performed and results of FNAC were correlated with those of USG reports and clinical features of the patient. <strong>Results:</strong> Out of 138 cases 83 (60.1%) cases were benign, 18(13.0%) cases were inflammatory, 2 (1.4%) cases were malignant, 28 (20.3%) were categorised as indeterminate, and 7 (5.1%) cases were inadequate. All the 2 malignant cases were given as neoplastic on USG. <strong>Conclusion:</strong> FNAC is the main diagnostic modality of choice for thyroid lesions, along with Ultrasonography and clinical examination it helps to come to the proper diagnosis.

scholarly journals Cytomorphological Profile of Thyroid Lesions on Fine Needle Aspiration Cytology

2021 ◽  
Vol 8 (7) ◽  
pp. 218-222
Author(s):  
Banasri Devi ◽  
Rachana Binayke ◽  
Brizellda Dcunha
Keyword(s):  
Thyroid Gland ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Bethesda System ◽  
Needle Aspiration Cytology ◽  
Thyroid Lesions ◽  
Gland Enlargement

Background and Objectives: Fine needle aspiration cytology (FNAC) of thyroid offers an alternative, as an immediate, preliminary procedure associated with low cost, little trauma and complications. Being superficial and easily accessible it is an ideal organ for FNAC. It is useful in diagnosis of inflammatory, infectious and neoplastic conditions. The aim of this study was to evaluate the cytomorphological profile of thyroid lesions on FNAC with application of Bethesda system for reporting and perform cyto-histopathology correlation whenever possible with regards to age and sex distribution. Methodology: This two-year prospective study was conducted in the Cytology section of Pathology Department & included 243 cases of thyroid gland enlargement. The detailed history of the patient including age, sex, presenting symptoms and duration of thyroid gland enlargement along with any other significant findings was note. FNAC was performed as per the protocol using a 23-gauge needle and smears stained using Haematoxylin & Eosin (H&E) and Papanicolaou stain, while air-dried smears were stained with Giemsa stain. Results: The study period included a total of 243 FNACs of thyroid enlargement. The age of patients ranged from 10 to 80 years with male to female ratio of 1.4. The diagnosis on FNAC was as follows Colloid Goitre (54.7 %), Lymphocytic Thyroiditis (9.54%), Follicular Neoplasm (7.05%), Hashimoto Thyroiditis (5.80 %), Benign Thyroid Lesions (3.31%) and Multinodular Goitre (2.90%). Conclusion: Thyroid fine needle aspiration cytology has proven to be a first line tool to evaluate the thyroid lesions because of its cost effectiveness and high patient acceptance. Fine needle aspiration cytology is highly successful in triaging patients with thyroid nodules into operative and non-operative groups and enables surgeons to take an early decision regarding mode of treatment. The Bethesda system for reporting of thyroid lesions aims at standardization of reports. It makes the cytology report unambiguous and clinically relevant. Keywords: Fine needle aspiration cytology, thyroid lesions.

CLINICAL, ENDOSCOPIC AND PATHOGICAL CHARACTERISTICS OF COLORECTAL CANCER AT DA NANG HOSPITAL FROM 2016 TO 2017

2018 ◽  
pp. 9-14
Author(s):  
Thanh Trung Nguyen ◽  
Duc Nhan Le ◽  
Van Xung Nguyen ◽  
Hieu Trung Doan
Keyword(s):  
Colorectal Cancer ◽  
Descriptive Study ◽  
Bloody Stool ◽  
Key Words Colorectal Cancer ◽  
Right Colon ◽  
Female Ratio ◽  
Histopathological Classification ◽  
Male Female Ratio ◽  
Female Male Female ◽  
Colorectal Cancer Patients

Objective: To study the clinical, endoscopy and pathogical characteristics of colorectal cancer at Da Nang Hospital. Methods: A retrospectively descriptive study, performed from 01/01/2016 to 31/12/2017 at Da Nang Hospital. Results: During two years, there were 205 cases of colorectal cancer patients hospitalized to Da Nang Hospital. Male: 59.51%, female: 40.49%, mean age: 65.8 ± 16.07. Male is higher than female, male/ female ratio is 1.4/1. The period from the first symptoms to admission < 3months predominated (83.8%). The predominant symptoms: Abdominal pain (85.85%), bloody stool (63.41%), defecation (62.44%), anemia (34.63%), weight loss (25.85%), fatigue (17.56%), abdominal distention (12.19%), nausea and vomiting (5.36%). Location of Lesions: Rectum (43.42%), sigmoid colon (20%), right colon (10.73%),cecum (10.73%), transverse colon (7.80%), left-colon (7.32%). Type of lesion on endoscopy: Exophytic (63.41%), ulceration-Exophytic (21.95%), ulceration (7.32%), polyp chemotherapy (7.32). Tumor size: ≥ 3/4 perimeter (39%), occupying the whole circumference (37.0%), occupying ≥ 1/2 perimeter (15.6%), accounting for 1/4 Perimeter (8.4%). The colon completely narrowed rate: 70.73%., incompletely was 29.27%. Histopathological classification: adenocarcinoma (85.85%), Mucinous adenocarcinoma: (9.27%) and non-differentiated epithelial carcinoma was 4.88%. Conclusion: Colorectal cancer was quite popular and was usually detected at advanced stages.Therefore, screening for subjects with risk factors for early detection and treatment is recommended. Key words: Colorectal cancer, endoscopy, pathogical characteristics...

ROLE OF FINE NEEDLE ASPIRATION CYTOLOGY (FNAC) IN BONE TUMORS AND TUMOR LIKE LESIONS

2021 ◽  
pp. 69-70
Author(s):  
Ragini Kumari ◽  
Vikash M. Harinandan ◽  
Kunal Shankar ◽  
Ajit Kumar Chaudhary ◽  
Debarshi Jana
Keyword(s):  
Fine Needle Aspiration ◽  
Bone Tumors ◽  
Needle Aspiration ◽  
Bone Lesions ◽  
Diagnostic Modality ◽  
Predictive Values ◽  
Female Ratio ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: FNAC is considered an important procedure in the diagnosis of bone tumors because of its high accuracy. In our study FNA was performed in patients to study the role of FNAC in the diagnosis of bone tumors and to evaluate its usefulness as a diagnostic modality. Methods: Fine needle aspiration was performed on 54 patients whose age ranged between 5 – 75 years with a male to female ratio 1.84 :1 presented with various bone lesions. The bone lesions included 42 (78%) primary lesions, 5 (9.3%) metastatic deposits and 7 (12. 7%) malignancy of related structures involving the bone. Results: 47 biopsy specimens were available for cytohistological correlation and cytological ndings of 45 cases correlated with histopathology. The overall diagnostic accuracy was 95.92%, with 100% sensitivity and specicity. The predictive values of positive as well as negative test were 100%. Conclusions:Thus FNAwas found to be a safe and an extremely useful, rapid method in the preliminary diagnosis of bone lesions.

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