scholarly journals Three New Flavonoid Glycosides from the Fruits of Luffa echinata Roxb.- a Hepatoprotective Plant

2017 ◽  
Vol 15 (2) ◽  
pp. 117-125
Author(s):  
Tanveer Alam ◽  
Ahmed Sulaeman Al Harrasi ◽  
Bahar Ahmed ◽  
Lubna Najam ◽  
Shah Alam Khan
Keyword(s):  
Spectral Data ◽  
Flavonoid Glycosides ◽  
Flavone Glycosides ◽  
Isolation And Characterization ◽  
Phytochemical Investigation ◽  
Polar Extracts

Phytochemical investigation of bioactive polar extracts of Luffa echinata Roxb. fruits led to the isolation and characterization of three new flavone glycosides viz., 3,5,7,3?,4?-pentahydroxyflavone-3-[-O-?-Dglucopyranosyl- 7-O-?-D-glucopyranoside (1),3,5,7-trihydroxy-(7?,8?- dioxo,9?,10?,-dihydro[a]cyclohex ?13?,(14?), ?11?(12’)-12?,13?,-dimethyl)-flavone-7-[-O-?-D-galactopyranosyl-(1?2)]-O-?-D-glucopyranoside (2), and 5,7,8,4?- tetrahydroxy flavone-7-[-O-?-D-xylosyl-(1?2)]-O-?-D-glucopyranoside (3). The structures of the newly isolated compounds were elucidated on the basis of spectral data and chemical evidences.The isolated compounds are found to be new analogs of tricetin, quercetin and isoscutellarin.Dhaka Univ. J. Pharm. Sci. 15(2): 117-125, 2016 (December)

Undescribed C-Glycosylflavones from Corn Silk and Potential Anti-inflammatory Activity Evaluation of Isolates

Planta Medica ◽  
2021 ◽  
Author(s):  
Satish Sarfare ◽  
Shabana Iqrar Khan ◽  
fazila zulfiqar ◽  
Srivedavyasasri Radhakrishnan ◽  
Zulfiqar Ali ◽  
...  
Keyword(s):  
Spectral Data ◽  
Structure Elucidation ◽  
2D Nmr ◽  
Inflammatory Activity ◽  
Inos Activity ◽  
Corn Silk ◽  
Activity Evaluation ◽  
Isolation And Characterization ◽  
Phytochemical Investigation

Phytochemical investigation of corn silk resulted in isolation and characterization of four flavone C-glycosides, chrysoeriol 6-C-β-oliopyranosyl-7-O-β-D-glucopyranoside (1), 3′-methoxycassiaoccidentalin A (2), chrysoeriol 6-C-β-boivinopyranosyl-7-O-β-D-glucopyranoside (3), and ax-4"-OH-3′-methoxymaysin (4), a triterpenoid, friedelin (5), two sterols, (22E)-5,8-epidioxyergosta-6,22-dien-3β-ol (6) and 6β-hydroxystigmasta-4,22-diene-3-one (7), and a mixture of β-sitosterol and stigmasterol. Compounds 1 and 2 were previously undescribed. Structure elucidation of the isolated compounds was attained using spectral data including 1D and 2D NMR and HRESIMS. Compounds 1, 2, 5, and 6 inhibited iNOS activity in LPS-induced macrophages and decreased nitrite levels by 68.64+4.46, 65.67 + 6.47, 88.50 + 0.50, and 94.00 + 4.00 %, respectively, at 50 µM. Compound 5 also showed inhibition of NF-κB (51.00+1.50 %). Compounds 1 and 2 induced NAG-1 activity in chondrocytes by 1.80 + 0.05 and 2.00 + 0.13 fold, respectively. The extract of corn silk, however, did not exhibit inhibition of iNOS or NF-κB but induced NAG-1 by 1.80+ 0.51 fold.

ISOLATION AND CHARACTERIZATION OF A NEW AROMATIC ESTER FROM THE SEEDS OF LENS CULINARIS MEDIK

INDIAN DRUGS ◽  
2014 ◽  
Vol 51 (05) ◽  
pp. 28-32
Author(s):  
M. Jameel ◽  
◽  
A. Ali ◽  
M. Ali
Keyword(s):  
Data Analysis ◽  
Spectral Data ◽  
Lens Culinaris ◽  
Aromatic Ester ◽  
Good Source ◽  
Essential Minerals ◽  
Isolation And Characterization ◽  
Phytochemical Investigation ◽  
Spectral Data Analysis

The seeds of Lens culinaris Medik, syn. L. esculenta Moench (Leguminosae) are a good source of essential minerals and are used to purify blood, to cure old skin marks and to treat various kidney and gastric ailments. Phytochemical investigation of the seeds led to isolation of a new aromatic ester characterized as 3'-methyl–n-pentadecanyl benzoate (3) along with β-sitosteryl n-octadec-9'-enoate (1), n -tetradecanyl linoleiate (2) and n-octatriacosanoic acid (4). The structures of these phytoconstituents have been established on the basis of spectral data analysis and chemical means.

scholarly journals Biflavonoids from the Unripe Fruits of Clusia Paralicola and their Antioxidant Activity

2012 ◽  
Vol 7 (12) ◽  
pp. 1934578X1200701 ◽  
Author(s):  
Rafaela Ferreira Oliveira ◽  
Celso Amorim Camara ◽  
Maria de Fátima Agra ◽  
Tania Maria Sarmento Silva
Keyword(s):  
Antioxidant Activity ◽  
Linoleic Acid ◽  
Spectral Data ◽  
2D Nmr ◽  
Cd Spectra ◽  
Total Extract ◽  
Isolation And Characterization ◽  
Β Carotene ◽  
Unripe Fruits

Investigation of the green fruits of Clusia paralicola (Clusiaceae) led to the isolation and characterization of two 3,8″-biflavonoids, 2R, 3S, 2″R, 3″R-GB1-7″- O-β-glucoside (1) and 2R, 3S, 2″R, 3,8″-binaringenin-7″-O-β-glucoside (2), together with four known compounds: β-sitosterol, stigmasterol, β-amyrin, and epicatechin. The structures were established from the IR, LC-ESI-MS and NMR spectral data, including 2D-NMR experiments. The absolute configurations of 1 and 2 were determined by CD spectra. The total extract and the biflavonoids demonstrated significant antioxidant activity in DPPH, ABTS, and β-carotene/linoleic acid tests.

scholarly journals Lagerindicine, a New Pyrrole Alkaloid Isolated from the Flowers of Lagerstroemia indica Linnaeus

2020 ◽  
Author(s):  
Yi Chen ◽  
Song-Wei Li ◽  
Fang-Zhou Yin ◽  
Min Yang ◽  
Xia-Juan Huan ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Spectroscopic Analysis ◽  
Human Colon ◽  
Human Colon Cancer ◽  
Cytotoxic Effects ◽  
Etoh Extract ◽  
Isolation And Characterization ◽  
Phytochemical Investigation ◽  
Hct 116

Abstract A phytochemical investigation of the EtOH extract of the flowers of Lagerstroemia indica L. led to the isolation and characterization of a new pyrrole alkaloid, named lagerindicine (1), along with four known compounds (2–5). Their structures were elucidated by the detailed spectroscopic analysis and comparison with literature data, whereas the structure, in particularly, the absolute configuration (AC) of 1, was firmly determined by total synthesis. All the isolates were evaluated for their cytotoxic effects against human colon cancer cell (HCT-116), and compound 3 exhibited weak cytotoxicity with IC50 value of 28.4 μM. Graphic Abstract

Semiquinol and phenol compounds from seven Senecio species

2011 ◽  
Vol 65 (1) ◽  
Author(s):  
Boris Mandić ◽  
Dejan Gođevac ◽  
Ljubodrag Vujisić ◽  
Snežana Trifunović ◽  
Vele Tesević ◽  
...  
Keyword(s):  
Spectroscopic Studies ◽  
1H And 13C Nmr ◽  
Serbia And Montenegro ◽  
Phenol Compounds ◽  
Aerial Parts ◽  
Isolation And Characterization ◽  
Phytochemical Investigation ◽  
Compound Ii ◽  
Tof Ms

AbstractIn this paper, examination of the aerial parts of seven Senecio species from Serbia and Montenegro is reported. Phytochemical investigation of Senecio erucifolius led to the isolation and characterization of semiquinol butyl 2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)acetate (I), along with methyl 2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)acetate (jacaranone, II), and methyl 2-(4-hidroxyphenyl)acetate (III). The structure of I was established based on spectroscopic studies (1H- and 13C-NMR, IR, and CI-MS). Compound II was also isolated from S. carpathicus and S. subalpinus. The presence of jacaranone in the methanol extracts of S. wagneri, S. othonnae, and S. paludosus was confirmed by LC/ESI-TOF MS.

Phytochemical Investigation, Isolation and Characterization of Coumarins from Aerial Parts and Roots of Tunisian Pituranthos chloranthus (Apiaceae)

2015 ◽  
Vol 5 (4) ◽  
pp. 237-243 ◽  
Author(s):  
Latifa Aloui ◽  
Mohamed Kossentini ◽  
Claude Geffroy-Rodier ◽  
Jérôme Guillard ◽  
Sami Zouari
Keyword(s):  
Aerial Parts ◽  
Isolation And Characterization ◽  
Phytochemical Investigation

scholarly journals Diterpenoid Alkaloids and Phenol Glycosides from Aconitum Naviculare (Brühl) Stapf

2008 ◽  
Vol 3 (12) ◽  
pp. 1934578X0800301 ◽  
Author(s):  
Stefano Dall'Acqua ◽  
Bharat B. Shrestha ◽  
Mohan Bikram Gewali ◽  
Pramod Kumar Jha ◽  
Maria Carrara ◽  
...  
Keyword(s):  
Human Tumor ◽  
2D Nmr ◽  
Diterpenoid Alkaloids ◽  
Human Tumor Cell Lines ◽  
Aerial Parts ◽  
Isolation And Characterization ◽  
Phytochemical Investigation ◽  
2D Nmr Spectra ◽  
Phenol Glycosides

Phytochemical investigation of the aerial parts of Aconitum naviculare, a medicinal plant used in traditional Nepalese medicine, led to the isolation and characterization of two new diterpenoid alkaloids, navirine B (1), and navirine C (2), along with (+) chellespontine (3), kaempferol-7-O-β-D-glucopyranosyl(1→3)α-L-rhamnopyranoside (4), kaempferol-7-O α-L-rhamnopyranoside,3-O-β-D-glucopyranoside (5), p-coumaric-4-O-β-D-glucopyranoside acid (6), and ferulic-4-O-β-D-glucopyranoside acid (7). The structures of the isolated compounds were elucidated on the basis of extensive analyses of 1D and 2D NMR spectra (HMQC, HMBC, COSY, ROESY) and HR-MS data. The antiproliferative activity of alkaloids 1–3 against human tumor cell lines (LoVo and 2008) was also evaluated.

scholarly journals Isolation and characterization of Stigmasta-7, 22-dien-3-ol (α-Spinasterol) from Entada africana stem bark crude extract

2019 ◽  
Vol 4 (3) ◽  
pp. 85
Author(s):  
A. Kwajia ◽  
H.M. Adamub ◽  
I.Y. Chindob
Keyword(s):  
Crude Extract ◽  
Spectroscopic Data ◽  
Soluble Fraction ◽  
Stem Bark ◽  
Literature Analysis ◽  
Bark Sample ◽  
Isolation And Characterization ◽  
Nmr Data ◽  
Phytochemical Investigation

The phytochemical  investigation of the stem bark extracts of Entada africana led to the isolation and characterization of Stigmasta-7,22-dien-3-ol from the dichloromethane soluble portion of acetone/methanol (1:1v/v) crude extract. The powdered stem bark sample of Entada africana was defatted with hexane and extracted with acetone/methanol (1:1v/v) mixture. The dichloromethane soluble fraction was purified on a low pressure column containing silica gel 60 (60-200 mesh). The purification afforded an isolate coded Enac3 (85 mg) with Rf value of 0.404 in hexane/ethyl acetate (4:1). The isolate was characterized using IR, NMR data and in comparison with literature. Analysis of spectroscopic data and literature comparison suggests Enac3 as stigmasta-7, 22-dien-3-ol. The isolation of stigmasta-7, 22-dien-3-ol from the stem bark of Entada africana suggests the presence of useful bioactive principles which could be exploited for medicinal purposes.

Isolation and Characterization of an Angular- Type Dihydropyranocoumaringlycoside from the Fruits of Ammi visnaga (L.) LAM. (Apiaceae)

1995 ◽  
Vol 50 (9-10) ◽  
pp. 729-731 ◽  
Author(s):  
H. Sonnenberg ◽  
M. Kaloga ◽  
N. Eisenbach ◽  
K.-K. Frömming
Keyword(s):  
Acid Hydrolysis ◽  
Spectral Data ◽  
Ammi Visnaga ◽  
Isolation And Characterization

Abstract An angular-type dihydropyranocoumaringlucoside, namely, cis-Khellactone-3′-β-D-glucopyranoside (1) was isolated from the fruits of Ammi visnaga (L.) LAM. (Apiaceae). The structure was established on the basis of acid hydrolysis and spectral data

scholarly journals 4-Hydroxy-trans-cinnamate Derivatives and Triterpene from Barleria cristata

2014 ◽  
Vol 12 (2) ◽  
pp. 143-145 ◽  
Author(s):  
Nipa Chowdhury ◽  
Abdullah Al Hasan ◽  
Fakir Shahidullah Tareq ◽  
Monira Ahsan ◽  
ATM Zafrul Azam
Keyword(s):  
Medicinal Plant ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Spectroscopic Methods ◽  
Isolation And Characterization ◽  
Phytochemical Investigation ◽  
Organic Extracts ◽  
Whole Plants ◽  
Important Medicinal Plant

Barleria cristata is an important medicinal plant of Bangladesh. Many compounds of diverse biological activities were isolated from different Barleria species, including irridoids, flavonoids and phenylethanoid derivatives in addition to other groups of chemical constituents. This paper presents the chemical investigation of the whole plants of B.cristata. Classic phytochemical investigation of organic extracts of the whole plants of B. cristata together with spectroscopic methods led to the isolation and characterization of 4-hydroxy-trans-cinnamate derivatives (1-3) and a triterpene, namely oleanolic acid (4). Dhaka Univ. J. Pharm. Sci. 12(2): 143-145, 2013 (December) DOI: http://dx.doi.org/10.3329/dujps.v12i2.17623

Sign in / Sign up

Export Citation Format

Share Document