scholarly journals Demographic Profile, Clinical Presentation & Angiographic Findings in 637 Patients with Coronary Heart Disease

1970 ◽  
Vol 6 (2) ◽  
pp. 82-85
Author(s):  
MAK Akanda ◽  
SY Ali ◽  
AEMM Islam ◽  
MM Rahman ◽  
A Parveen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Surgical Treatment ◽  
Coronary Angiography ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Vessel Disease ◽  
Adult Congenital

Cardiovascular diseases are the commonest cause of death globally and are the major contributor to the burden of premature mortality and morbidity. This study analyses various clinical presentations, conventional risk factors, pattern and severity of coronary heart disease on angiography among 637 patients with coronary heart disease and adult congenital heart disease who underwent cardiac evaluation at National Institute of Cardiovascular Disease (NICVD), Dhaka between January 2007 to December 2008. Among them 547 (85.9%) were male and 90 (14.1%) were female. All of them were between 22 to 76 years of age with mean age 50.15±8.8. One hundred sixty nine (25.9%) patients had chronic stable angina & 398 (62.48%) patients subjected for coronary angiography for acute coronary syndrome and or old myocardial infarction and 74 (11.62%) patients with vascular and adult congenital heart disease prior to surgical treatment. Most prevalent risk factors were smoking (60%) and dyslipidaemia (60%). Thirty five percent patients were hypertensive and 10% patient had diabetes. Normal epicardial coronaries were documented in 25.59% patients which includes the patients who underwent coronary angiography prior to surgical treatment. Ninety three (14.6%) had single vessel disease, 119 (18.68%) had double vessel disease, 259 (40.66%) had triple vessel disease and 3 (0.47%) had isolated left main disease. Key words: Coronary angiogram; Coronary artery disease. DOI: http://dx.doi.org/10.3329/fmcj.v6i2.9206 FMCJ 2011; 6(2): 82-85

Abstract 240: Hypertension Prevalence and Management Among Adult Congenital Heart Disease Patients

Hypertension ◽  
2014 ◽  
Vol 64 (suppl_1) ◽  
Author(s):  
Joshua R Thomas ◽  
Ricky T Munoz ◽  
Mark D Fox ◽  
Angela T Yetman
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Hypertension Prevalence ◽  
Significant Difference ◽  
Adult Congenital ◽  
The Mean

Background: Cardiovascular risk factors (CRFs) are poorly defined among the population of adults with congenital heart disease. In particular, the prevalence of pre-hypertension (pre-HTN) and hypertension (HTN) are currently unknown. Objective: To determine the prevalence of pre-HTN and HTN among adults with congenital heart disease; and to assess HTN control rates among different clinic types. Methods: A retrospective analysis of a cohort of adults with congenital heart disease (CHD) was conducted. Data regarding CHD patients' blood pressure (BP), medications, and provider specialty were analyzed. Results: The cohort consisted of 971 patients. The mean age was 30.4 years (SD = 10.4), with 51% male. Thirty-two percent had HTN (n = 304). There was no statistically significant difference in the prevalence of Pre-HTN and HTN by clinic type (i.e. specialty vs. non-specialty)( p = .225, p= .633 respectively). However, a statistically significant association exists between clinic type and HTN control rates χ 2 (1) = 3.185, p = .07 (Table 1). Those receiving care from a specialty clinic are 1.6 times more likely to have controlled HTN. Conclusions: Pre-HTN and HTN are common among adults with congenital heart disease. These CRFs are better managed in specialty clinics devoted to this population.

Surgical treatment for adult congenital heart disease: consideration for indications and procedures

2017 ◽  
Vol 66 (2) ◽  
pp. 57-64 ◽  
Author(s):  
Kozo Matsuo ◽  
Masashi Kabasawa ◽  
Soichi Asano ◽  
Shigeru Tateno ◽  
Yasutaka Kawasoe ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Surgical Treatment ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Adult Congenital

scholarly journals Depression requiring anti-depressant drug therapy in adult congenital heart disease: prevalence, risk factors, and prognostic value

2015 ◽  
Vol 37 (9) ◽  
pp. 771-782 ◽  
Author(s):  
Gerhard-Paul Diller ◽  
Andrea Bräutigam ◽  
Aleksander Kempny ◽  
Anselm Uebing ◽  
Rafael Alonso-Gonzalez ◽  
...  
Keyword(s):  
Risk Factors ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Drug Therapy ◽  
Prognostic Value ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Disease Prevalence ◽  
Adult Congenital ◽  
Depressant Drug

scholarly journals 488 Candidacy for heart transplantation in adult congenital heart disease patients: a single-centre, retrospective, cohort study

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Emanuela Concetta D’Angelo ◽  
Emanuela Angeli ◽  
Luca Ragni ◽  
Gaetano Domenico Gargiulo ◽  
Andrea Donti ◽  
...  
Keyword(s):  
Risk Factors ◽  
Congenital Heart Disease ◽  
Cohort Study ◽  
Heart Disease ◽  
High Risk ◽  
Retrospective Cohort ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Adult Congenital ◽  
End Stage

Abstract Aims End-stage heart failure (HF) is the leading cause of death in adult congenital heart disease (ACHD) population. Heart transplantation (HTx) improves prognosis in ACHD end-stage HF but candidacy evaluation, referral pattern, and correct listing timing are not fully elucidated in this population. To evaluate factors associated to refusal from Htx in ACHD patients with end-stage HF referred for HTx evaluation. Methods and results This retrospective cohort study enrolled consecutive ACHD patients considered for HTx in our institution between 2014 and 2020 and patients undergone HTx between 2000 and 2013. Refusal from HTx served as primary study endpoint. Between 2014 and 2020, 46 ACHD patients were evaluated for HTx, 14 ACHD patients underwent HTx between 2001 and 2013. The main indication to HTx in patients with single ventricle physiology was Fontan failure, while in patients with systemic left ventricle and systemic right ventricle physiology, it was systemic ventricular dysfunction. We compared clinical, anatomical and demographic data of 41 patients accepted for transplantation with 15 patients refused after screening. Risk factors for refusal were: coexistence of multiple high risk features [odds ratio (OR): 3.6; 95% confidence interval (CI): 1.1–12.9; P 0.048]; anatomical factors (OR: 14.5; 95% CI: 3.1–68.4; P 0.001), out-of-centre ACHD/HTx program referral (OR: 5.3; 95% CI: 1.5 to 19.0; p 0.01). Survival in patients accepted for HTx was significantly higher than survival in patients declined from HTx with landmark comparison at 20, 40 and 60 months of 87%, 78%, and 72% vs. 70%, 59%, and 20%, respectively. HTx refusal identifies a high risk ACHD patient subgroup (hazard ratio for overall mortality: 3.1; 95% CI: 1.1–8.3; P 0.02). Conclusions In our study risk factors for refusal from HTx are adverse anatomical features, coexistence of multiple conventional HTx high risk factors and out-of-centre referral. ACHD patients refused from HTx present shorter time to death. Efforts to increase HTx candidacy and to reduce referral delay in tertiary centre are strongly necessary for this growing population.

scholarly journals Heart failure related to adult congenital heart disease: prevalence, outcome and risk factors

2021 ◽  
Author(s):  
Stijn Arnaert ◽  
Pieter De Meester ◽  
Els Troost ◽  
Walter Droogne ◽  
Lucas Van Aelst ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Disease Prevalence ◽  
Adult Congenital

scholarly journals Clinical outcome of COVID-19 in patients with adult congenital heart disease

Heart ◽  
2021 ◽  
pp. heartjnl-2020-318467
Author(s):  
Markus Schwerzmann ◽  
Francisco Javier Ruperti-Repilado ◽  
Helmut Baumgartner ◽  
Berto Bouma ◽  
Judith Bouchardy ◽  
...  
Keyword(s):  
Risk Factors ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Clinical Outcome ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Disease Course ◽  
Cyanotic Heart Disease ◽  
Cardiac Defects ◽  
Adult Congenital

AimsPatients with adult congenital heart disease (ACHD) are a potentially vulnerable patient cohort in case of COVID-19. Some cardiac defects may be associated with a poor COVID-19 outcome. Risk estimation in ACHD is currently based on expert opinion. The aim of this study was to collect clinical outcome data and to identify risk factors for a complicated course of COVID-19 in patients with ACHD.MethodsTwenty-five ACHD centres in nine European countries participated in the study. Consecutive patients with ACHD diagnosed with COVID-19 presenting to one of the participating centres between 27 March and 6 June 2020 were included. A complicated disease course was defined as hospitalisation for COVID-19 requiring non-invasive or invasive ventilation and/or inotropic support, or a fatal outcome.ResultsOf 105 patients with a mean age of 38±13 years (58% women), 13 had a complicated disease course, of whom 5 died. In univariable analysis, age (OR 1.3, 95% CI 1.1 to 1.7, per 5 years), ≥2 comorbidities (OR 7.1, 95% CI 2.1 to 24.5), body mass index of >25 kg/m2 (OR 7.2, 95% CI 1.9 to 28.3) and cyanotic heart disease (OR 13.2, 95% CI 2.5 to 68.4) were associated with a complicated disease course. In a multivariable logistic regression model, cyanotic heart disease was the most important predictor (OR 60.0, 95% CI 7.6 to 474.0).ConclusionsAmong patients with ACHD, general risk factors (age, obesity and multiple comorbidities) are associated with an increased risk of complicated COVID-19 course. Congenital cardiac defects at particularly high risk were cyanotic lesions, including unrepaired cyanotic defects or Eisenmenger syndrome.

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