scholarly journals Parasympathetic Nerve Function Status During Different Phases Of Menstrual Cycle In Healthy Young Women

1970 ◽  
Vol 6 (2) ◽  
pp. 100-107 ◽  
Author(s):  
Rama Choudhury ◽  
Nasim Jahan ◽  
Nayma Sultana ◽  
Rezina Akter ◽  
Ayesha Akhter Khanum
Keyword(s):  
Menstrual Cycle ◽  
Luteal Phase ◽  
Follicular Phase ◽  
Parasympathetic Activity ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Deep Breathing ◽  
Parasympathetic Nerve ◽  
Autonomic Nerve Function ◽  
Late Luteal Phase

Background: Autonomic nerve function status may be changed during follicular and late luteal phases of menstrual cycle due to fluctuations of serum estrogen and progesterone levels. This alteration in autonomic nerve functions may affect cardiovagal control and usually associated with decreased parasympathetic activity in late luteal phase. Objective: To observe the parasympathetic nerve function status during follicular and late luteal phases of menstrual cycle and also their relationships with serum estrogen and progesterone levels in healthy young women. Methods: This cross-sectional study was carried out in the Department of Physiology, Sir Salimullah Medical College (SSMC), Dhaka from 1st January 2009 to 31st December 2009. A total number of thirty (30) apparently healthy unmarried women age ranged from 20-25 years were studied in both follicular (phase A, control) and late luteal (phase B, study) phases of menstrual cycle. Simple autonomic nerve function tests like heart rate (HR) response to valsalva maneuver (valsalva ratio), HR response to deep breathing, HR response to standing (30th:15th ratio) were done to assess parasympathetic activity and serum estrogen and progesterone levels were also measured by AxSYM method. All these tests were performed in both follicular and late luteal phases of menstrual cycle of the same subject. Data were analysed by paired student’s ‘t’ test and Pearson’s correlation coefficient test as applicable. Results: Mean values of both HR response to valsalva ratio and HR response to standing (30th:15 th ) were non-significantly decreased but HR response to deep breathing was significantly (p<0.05) decreased in late luteal phase than those of follicular phase. Conclusion: From this study it can be concluded that parasympathetic activity is decreased in late luteal phase of menstrual cycle. DOI: http://dx.doi.org/10.3329/jbsp.v6i2.9759 JBSP 2011 6(2): 100-107

scholarly journals Ovarian Hormones During Different Phases of Ovarian Cycle In Healthy Young Women

2013 ◽  
Vol 7 (2) ◽  
pp. 83-88
Author(s):  
Latifa Afrin Dill Naher ◽  
Noorzahan Begum ◽  
Sultana Ferdousi
Keyword(s):  
Young Women ◽  
Luteal Phase ◽  
Ovarian Hormones ◽  
Ovarian Cycle ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Deep Breathing ◽  
Cross Sectional ◽  
Parasympathetic Nerve ◽  
Positive Correlation

Background: Women having regular ovarian cycle often experience premenstrual syndrome which may be associated with alterations of autonomic nerve function due to fluctuation of ovarian hormones during different phases of ovarian cycle. Objective: To observe the parasympathetic nerve function status and their relationships with ovarian hormones during different phases of ovarian cycle in healthy young women. Methods: This cross sectional study was carried out in the department of Physiology at BSMMU, Dhaka in 2007 on 30 eumenorrhogic healthy females aged 20 to 30 years. Serum estrogen and progesterone were measured by MEIA method and parasympathetic nerve functions were assessed by valsalva, deep breathing test and orthostatic test during follicular and luteal phases of ovarian cycle. Data were analyzed by paired student ‘t’ test, and Pearson’s Correlation coefficient test where applicable. Results: Mean resting HR,SBP,DBP and all measures of parasympathetic nerve function were similar in all phases of ovarian cycle. With serum estrogen level, deep breathing showed significant (p<0.05) positive correlation in follicular and luteal phase and valsalva showed significant positive correlation during luteal phase. Conclusion: The results this study suggest that estrogen has got positive influence on parasympathetic nerve function which support cardioprotective role of estrogen in premenopausal females. DOI: http://dx.doi.org/10.3329/jbsp.v7i2.14456 J Bangladesh Soc Physiol. 2012, December; 7(2): 83-88

scholarly journals Sympathetic Nerve Function Status in Follicular and Late Luteal Phases of Menstrual Cycle in Healthy Young Women

1970 ◽  
Vol 5 (2) ◽  
pp. 80-88
Author(s):  
Rama Choudhury ◽  
Nasim Jahan ◽  
Nayma Sultana ◽  
Rezina Akter ◽  
Ayesha Akhter Khanum
Keyword(s):  
Blood Pressure ◽  
Menstrual Cycle ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Sympathetic Nerve ◽  
Sympathetic Activity ◽  
Luteal Phase ◽  
Follicular Phase ◽  
Nerve Function ◽  
Late Luteal Phase

Background: Autonomic nerve function status may be changed during follicular and late luteal phases of menstrual cycle due to fluctuations of serum estrogen and progesterone level. Objective: To observe the sympathetic nerve function status during follicular and late luteal phases of menstrual cycle and their relationships with serum estrogen and progesterone in healthy young womens. Methods: This cross-sectional study was carried out in the Department of Physiology, Sir Salimullah Medical College, Dhaka from 1st January 2009 to 31st December 2009.A total number of thirty (30) apparently healthy unmarried women with age ranged from 20-25 years were investigated. Two simple autonomic nerve function tests, like fall of systolic blood pressure (SBP) on standing and rise of diastolic blood pressure (DBP) during handgrip were done to assess sympathetic activity. Serum estrogen and progesterone levels were also measured by AxSYM method. All these tests were performed in both follicular and late luteal phases of menstrual cycle. Data were analysed by paired student’s ‘t’ test and Pearson’s correlation coefficient test as applicable. Results: Mean resting heart rate was significantly (p<0.01) increased in late luteal phase than that of follicular phase. Mean resting systolic blood pressure was significantly (p<0.01) increased and resting diastolic blood pressure was non-significantly increased in late luteal phase than those of follicular phase. Again, significantly (p<0.05) increased value of fall of systolic blood pressure after standing from lying and non-significant increased value of rise in diastolic blood pressure after sustained handgrip were observed in late luteal phase. The mean value of serum estrogen was non-significantly and serum progesterone was significantly (p<0.001) increased in late luteal phase than those of follicular phase. Conclusion: From this study it can be concluded that sympathetic activity is increased in late luteal phase of menstrual cycle. In addition, increased sympathetic activity during late luteal phase might be the cause of premenstrual syndrome (PMS) in some women. Key words: Sympathetic nerve functions; progesterone. DOI: 10.3329/jbsp.v5i2.6782J Bangladesh Soc Physiol. 2010 December; 5(2): 80-88

scholarly journals Relationship Between Obesity And Parasympathetic Nerve Function

1970 ◽  
Vol 3 ◽  
pp. 50-54
Author(s):  
Shahin Akhtar ◽  
Noorzahan Begum ◽  
Sultana Ferdousi ◽  
Shelina Begum ◽  
Taskina Ali
Keyword(s):  
Heart Rate ◽  
Heart Rate Response ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Deep Breathing ◽  
Parasympathetic Nerve ◽  
Autonomic Nerve Function ◽  
Obese Subjects ◽  
Healthy Obese ◽  
Apparently Healthy

Back ground: Obesity is a potential risk factor for cardiovascular morbidity and mortality. As certain cardiovascular disorders associated with autonomic nerve which dysfunction often coexist in obese persons, investigations of autonomic nerve function especially parasympathetic nerve function in obese, for detection of early autonomic impairment can be potentially important to prevent complications. Objective: The present study was done to observe the parasympathetic nerve function status in obese persons in order to investigate the relationship of autonomic nerve function with obesity. Study design: This study was conducted in the department of Physiology of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh during July 2006-June 2007. For these 40 apparently healthy obese subjects of both sexes with BMI ≥ 25 kg/sqm. were included in study group. Age and sex matched 40 apparently healthy non obese subjects with BMI range 18.5-22.9 kg/sqm. were taken as control for comparison. Methods: To assess parasympathetic nerve function status, heart rate response to valsalva(valsalva ratio), heart rate response to deep breathing and heart rate response to standing (30th:15th ratio) were determined by 3 noninvasive cardiovascular reflex tests. Data were collected by recording ECG of all subjects under test condition. The correlations of these parasympathetic nerve function parameters with BMI were also studied. Unpaired Student ‘t' test and Pearson correlation coefficient test were used for statistical analysis. Results: Valsalva ratio (1.47±0.24 vs 1.67±0.31), HR response to deep breathing (19.62±5.55 vs 27.59±6.51) and HR response to standing (1.07±0.07 vs 1.13±0.018) were significantly decreased in obese subjects than those of non obese control. All these parameters were negatively correlated with BMI. and these relatioship were statistically significant. Conclusion: The results of this study indicate that parasympathetic nerve function may be reduced in apparently healthy obese subjects. Key words: Obesity; valsalva; parasympathetic; deep breathing.   doi: 10.3329/jbsp.v3i0.1797 J Bangladesh Soc Physiol.2008 Dec;(3):50-54.

Response to flumazenil in the late luteal phase and follicular phase of the menstrual cycle in healthy control females

2004 ◽  
Vol 172 (3) ◽  
pp. 248-254 ◽  
Author(s):  
Emily C. Bell ◽  
Glen B. Baker ◽  
Christina Poag ◽  
Francois Bellavance ◽  
Janisse Khudabux ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Luteal Phase ◽  
Follicular Phase ◽  
Late Luteal Phase ◽  
Healthy Control

THE SEQUENCE OF PITUITARY RESPONSES TO SYNTHETIC LUTEINIZING HORMONE RELEASING HORMONE (LH-RH) THROUGHOUT THE NORMAL MENSTRUAL CYCLE

1975 ◽  
Vol 79 (4) ◽  
pp. 625-634 ◽  
Author(s):  
Elwyn M. Grimes ◽  
Irwin E. Thompson ◽  
Melvin L. Taymor
Keyword(s):  
Menstrual Cycle ◽  
Luteal Phase ◽  
Follicular Phase ◽  
Lh Surge ◽  
Luteinizing Hormone Releasing Hormone ◽  
Late Luteal Phase ◽  
Normal Menstrual Cycle ◽  
Early Follicular Phase ◽  
Lh Rh ◽  
Late Follicular Phase

ABSTRACT Thirty-one ovulatory women between 20 and 33 years of age were given 150 μg of synthetic LH-RH during different phases of the menstrual cycle. Five patients were studied during the early follicular phase (days 4–7); 10 patients during the late follicular phase (days 9–12); 6 patients during the "LH Surge"; 5 patients during the early luteal phase (days 14–16); 3 patients during mid-luteal phase (days 17–21); and 2 patients during late luteal phase (days 22–27). Oestrogen, progesterone, FSH and LH levels were determined from 30 min prior to LH-RH administration to 90 min thereafter in all cases. LH response to LH-RH increased progressively during the follicular phase. Enhanced pituitary responsiveness to LH-RH occurred at mid-cycle for both LH and FSH and maximum LH responses occurred during the "LH Surge" and early luteal phase. LH responses during the mid and late luteal phases were similar to late follicular phase responses. There were no significant differences between FSH responses during the early follicular, late follicular, mid-luteal and late luteal phases. Maximum pituitary responsiveness appears to occur in a gonadal steroid milieu of high oestrogen levels in association with rising but low progesterone levels. Progesterone or a crucial oestrogen: progesterone ratio may in fact potentiate pituitary release of LH during the early stages of corpus luteum formation. Pituitary responsiveness to LH-RH correlates positively with basal LH and oestrogen levels during the menstrual cycle and with the oestrogen:progesterone ratio during the luteal phase.

scholarly journals The menstrual cycle affects recognition of emotional expressions: an event-related potential study

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 853 ◽  
Author(s):  
Madoka Yamazaki ◽  
Kyoko Tamura
Keyword(s):  
Menstrual Cycle ◽  
Facial Expressions ◽  
Cognitive Processing ◽  
Luteal Phase ◽  
Follicular Phase ◽  
Event Related Potential ◽  
Reproductive Age ◽  
Cycle Phase ◽  
Late Luteal Phase ◽  
The Relationship

Background: Several studies have investigated the relationship between behavioral changes and the menstrual cycle in female subjects at a reproductive age. The present study investigated the relationship between the menstrual cycle and emotional face recognition by measuring the N170 component of ERPs. Methods: We measured N170 of twelve women in both follicular phase and late luteal phase who were presented with human facial expressions as stimuli (happy and angry). Results: In the follicular phase, participants showed a significantly larger response to happy male facial expressions. In the late luteal phase, participants had longer reaction times to all emotional stimuli, and a significantly reduced response to happy faces, especially happy male facial expressions (P<0.001). Conclusions: Our findings suggest that the menstrual cycle modulates early visual cognitive processing, and highlight the importance of considering the menstrual cycle phase in studies that investigate emotion and cognition.

scholarly journals Parasympathetic Nerve Function Status in Major Depressive Disorder Patients and Its Correlation with Duration of Disease

2020 ◽  
Vol 32 (2) ◽  
pp. 76-80
Author(s):  
Choudhury Rifat Jahan ◽  
Md Moyeen Uddin ◽  
Md Samir Uddin ◽  
Misbah Ul Hoq Chowdury ◽  
Wajeunnesa ◽  
...  
Keyword(s):  
Heart Rate ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Major Depressive ◽  
Parasympathetic Nerve ◽  
Autonomic Nerve Function ◽  
Duration Of Disease ◽  
Drug Naïve

Introduction:Cardiovascular (CV) morbidity is a major problem in patients suffering from depression. Greater CV mortality is found in cardiac patients with depression than without depression. Depressive disorder can cause altered autonomic nerve function. This study design to assess autonomic nerve function activity by heart rate variability analysis in patients with major depressive disorder and its correlation with duration of disease. Materials and Methods: This case study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka in 2011. 60 patients of both sexes with major depressive disorder (MDD) aged from 20-50 years were included in the study group (Group B). The patients were selected from out and inpatient Department of Psychiatry in Bangabandhu Sheik Mujib Medical University (BSMMU). Group B were divided into B-1 consisting of 30 drug naive MDD patients & B-2 consisting of 30 medicated MDD patients. For comparison age and sex matched 30 apparently healthy subjects (Group A) were also studied. The HRV parameters were recorded by 4 active channels, Polyrite-D machine. For statistical analysis ANOVA, independent sample t-test, chi-square test and Pearson’s correlation coefficient test were performed by using SPSS for windows version-16 as applicable. Results: Mean resting pulse rate, mean heart rate, systolic blood pressure were significantly higher in drug naive and medicated MDD patients in comparison with that of healthy control. Mean R-R interval, Max/Min R-R interval, SDNN, RMSSD, PNN50%, NN50% were significantly lower in this groups of patients. Correlation analysis showed negative correlations of SDNN, RMSSD, PNN50%, NN50% with disease duration which was statistically significant only for SDNN. Conclusion: Sympathovagal imbalance may occur in both drug naive and medicated MDD patients which is associated with higher sympathetic and lower vagal modulation of the heart rate. In addition, parasympathetic nerve function parameters show negative relationship with the duration of disease. Medicine Today 2020 Vol.32(2): 76-80

scholarly journals Heart Rate Variability in Patients with Essential Hypertension

1970 ◽  
Vol 5 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Rehnuma Tabassum ◽  
Noorzahan Begum ◽  
Sultana Ferdousi ◽  
Shelina Begum ◽  
Taskina Ali
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Essential Hypertension ◽  
Time Domain ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Parasympathetic Nerve ◽  
Hypertensive Patients ◽  
Autonomic Nerve Function ◽  
Normotensive Subjects

Background: Essential hypertension may be associated with altered cardiovascular autonomic nervefunction. Heart Rate Variability (HRV) analysis is an important tool for quantitative measurement ofautonomic nerve activity. Objective: To assess the cardiac autonomic nerve function status in essentialhypertension by analyzing time domain measures of heart rate variability. Methods: This cross sectional study was carried out in the Department of Physiology, Bangabandhu Sheikh Mujib MedicalUniversity from 1st July 2008 to 30th June 2009.For this purpose, 60 hypertensive male patients withage ranged between 40-60 years (group B) were enrolled from the Out Patient Department of Cardiology,BSMMU, Dhaka. Based on treatment received, hypertensive patients were subdivided into group B1i.e.untreated patients on their 1st day of diagnosis and group B2 i.e.patients with antihypertensivetherapy. For comparison, 30 age & sex matched apparently healthy normotensive subjects (group A)were also studied as control group. Time domain measures of Heart Rate Variability (HRV) such asMean RR intervals, Mean HR, SDNN & RMSSD were assessed by a Polygraph machine to observeboth sympathetic and parasympathetic nerve function status. For statistical analysis of data,Independent sample t-test, One-way ANOVA test, were used as applicable. Results: Mean R-R interval SDNN and RMSSD were significantly (P<0.01) lower but mean heart rate was significantly (P<0.01)higher in untreated hypertensive patients than those of normotensive subjects. But differences in allthese 4 parameters when compared between control and treated hypertensive patients were foundstatistically non significant. Conclusion: Impaired cardiac autonomic nerve function characterized bysympathetic overactivity may occur in hypertensive patients.Key words: Mean RR; SDNN; RMSSD; hypertensionDOI: 10.3329/jbsp.v5i1.5411J Bangladesh Soc Physiol. 2010 June; 5(1): 1-7

scholarly journals Prostate-specific antigen in serum during the menstrual cycle

1997 ◽  
Vol 43 (10) ◽  
pp. 1862-1867 ◽  
Author(s):  
Nosratollah Zarghami ◽  
Linda Grass ◽  
Edward R Sauter ◽  
Eleftherios P Diamandis
Keyword(s):  
Menstrual Cycle ◽  
Cell Line ◽  
Prostate Specific Antigen ◽  
Luteal Phase ◽  
Specific Antigen ◽  
Follicular Phase ◽  
Breast Carcinoma Cell Line ◽  
Late Luteal Phase ◽  
Late Follicular Phase

Abstract We previously found that prostate-specific antigen (PSA) expression in the female breast is regulated by steroid hormones and their receptors. We have now examined whether the PSA concentration in serum changes during the menstrual cycle of healthy women. Among 14 women studied, 3 had serum PSA ≥4 ng/L; their changes in PSA content during the menstrual cycle were studied in 7 informative cycles. We found that PSA concentrations in serum are highest during the mid- to late follicular phase, drop continuously with a half-life of 3–5 days between the late follicular phase and midcycle, and reach a minimum during the mid- to late luteal phase. PSA changes do not correlate with changes in lutropin (LH), follitropin (FSH), or estradiol concentrations. However, PSA peaks seem to follow the progesterone concentration peaks, with a delay of 10–12 days. Sera of some volunteers were tested for their ability to upregulate PSA protein and PSA mRNA in a tissue culture system based on the T-47D breast carcinoma cell line. Only sera obtained during the mid- to late luteal phase were able to upregulate the PSA mRNA and protein. In stimulation experiments in vitro, progesterone, but not LH, FSH, estradiol, human chorionic gonadotropin, prolactin, or growth hormone, was able to upregulate PSA mRNA and protein in the T-47D cell line. These data suggest that PSA is produced in a cyclical manner during the menstrual cycle.

scholarly journals Parasympathetic Nerve Function Status in Female with Rheumatoid Arthritis

2013 ◽  
Vol 8 (1) ◽  
pp. 21-25
Author(s):  
Kawser Jahan ◽  
Noorzahan Begum ◽  
Sultana Ferdousi
Keyword(s):  
Rheumatoid Arthritis ◽  
Heart Rate ◽  
Heart Rate Response ◽  
Valsalva Maneuver ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Deep Breathing ◽  
Cross Sectional ◽  
Parasympathetic Nerve ◽  
Mean Values

Background: Sudden cardiac death in patients with Rheumatoid Arthritis has been attributed to the decreased vagal drive to the heart. Objective: To assess cardiac parasympathetic nerve function status in patients with Rheumatoid Arthritis (RA). Methods: This cross sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka from January to December 2010. Sixty female RA patients aged 18-50 years were included in the study group. They were enrolled from the Out Patient Department of Rheumatology Wing of the Department of Medicine, BSMMU, Dhaka. For comparison age matched thirty apparently healthy females were also studied as control. To assess parasympathetic nerve function status, all the subjects were examined by three noninvasive cardiovascular reflex tests such as heart rate response to valsalva maneuver (valsalva ratio), heart rate response to deep breathing and heart rate response to standing (30th :15th ratio). For statistical analysis independent sample t test was used. Results: Mean values of valsalva ratio, deep breathing test and 30th :15th ratio were significantly (p<0.001) lower in rheumatoid arthritis patients compared to those of healthy control. Conclusion: From this study it may be concluded that lower cardiac parasympathetic nerve activity characterized the autonomic nerve dysfunction in patients with Rheumatoid Arthritis. DOI: http://dx.doi.org/10.3329/jbsp.v8i1.16643 J Bangladesh Soc Physiol. 2013, June; 8(1): 21-25

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