scholarly journals Prevalence of fatty liver in type 2 Diabetic patients: Experience from northern Bangladesh

2018 ◽  
Vol 27 (2) ◽  
pp. 11-13
Author(s):  
M Akhtarul Islam ◽  
PM Basak ◽  
BC Sarkar ◽  
MMR Khan ◽  
MM Khanam ◽  
...  

This study was done to find out the prevalence of fatty liver in type2 Diabetic patients. This was a descriptive cross-sectional comparative study carried out in Department of Medicine, Rajshahi Medical College Hospital and Rajshahi Diabetic Association Hospital from July 2008 to June 2010. 100 (one hundred) diagnosed type2 diabetic patients were included. All of those study population were free from taking any hepatoxic drugs and free from any preexisting liver disease. This exclusion was done by history, through clinical examination and relevant investigations. Among 100 type2 diabetic patients, 66 (66%) had normal, 25 (25%) had mild fatty change, 6 (6%) had moderate fatty change in liver; 2 (2%) had mild hepatomegally and 1 (1%) had congested liver. Non had cirrhosis or hepatocellular carcinoma.TAJ 2014; 27(2): 11-13

2018 ◽  
Vol 29 (1) ◽  
pp. 21-23
Author(s):  
M Akhtarul Islam ◽  
MMR Khan ◽  
PM Basak ◽  
MM Khanam ◽  
PM Bhattacharyya

This was a descriptive cross-sectional comparative study carried out in Department of Medicine, Rajshahi Medical College Hospital and Rajshahi Diabetic Association Hospital from July 2008 to June 2010. 100 (one hundred) diagnosed type2 diabetic patients and 30 apparently healthy people were included. All of those study population were free from taking any hepatoxic drugs and free from any preexisting liver disease. This exclusion was done by history, through clinical examination and relevant investigations. The prevalence of abnormal serum bilirubin, ALT, AST, Alkaline phosphatase, prothrombin time and S. albumin were 6%, 30%, 7%, 6%, 54% and 12% respectively in type2 diabetic patients and 00%, 3.3%, 00%, 6.7%, 10% and 3.3% respectively in normal people. All the LFTs of type 2 diabetic patients were mildly abnormal except 2 patients (2%) had moderate elevation of ALT, 7 patient (7%) had markedly prolonged PT, and 1 patient (1%) had moderately decreased s. albumin. In normal people all LFTs abnormalities were mild.TAJ 2016; 29(1): 21-23


2014 ◽  
Vol 3 (1) ◽  
pp. 20-24
Author(s):  
Md Muzibar Rahman ◽  
Zahid Hassan ◽  
Bina Sen ◽  
ASM Shahidullah ◽  
Arup Ratan Paul ◽  
...  

A cross sectional study of 129 type 2 diabetic patients attending out patient department of Community Based Medical College Hospital was done with an aim to evaluate their metabolic control. Of the total cases, 88 (68.2%) were male and 41 (31.8%) were female. Blood glucose and lipid levels were measured by following the standard laboratory methods. The study subjects had relatively poor glycemic control. Fasting serum glucose was 7.45±2.71 (mmol/l, mean±SD); Male-7.04±2.36 and Female 8.33±3.20, p=ns'. Mean (±SD) of total cholesterol and triglyceride of the female subjects were significantly higher compared to the male counterpart (p=0.01 for both). About 71% and 78.0% female subjects had triglyceride and HDLc abnormality compared to 63.3% and 61.4% respectively in their male counterpart. Fasting glucose level showed significant positive correlation with triglyceride among total and male study subjects (p=0.003 for both). In case of total cholesterol significant positive association was among total and female subjects (p=0.005 and 0.007 respectively).  The data concluded that (i) relatively large number of diabetic patients were having dyslipidemia of either component or in combination; and (ii) attention needs to be paid to address this issue of dyslipidemia and to avoid or at least delay the coronary artery and atherosclerotic complications of these subjects. CBMJ 2014 January: Vol. 03 No. 01 P: 20-24


KYAMC Journal ◽  
2019 ◽  
Vol 10 (2) ◽  
pp. 95-98
Author(s):  
Kamrunnahar Alo ◽  
Shyamal Chandra Banik ◽  
Safayet Ahammed ◽  
Ayesha Yasmin ◽  
Tania Rahman

Background: Thyroid dysfunction specially hypothyroidism may occur in type 2 diabetic patients. Objective: To observe thyroid function status in type 2 diabetic patients Materials and Methods: This cross sectional study was carried out in the Department of Physiology, Sir Salimullah Medical College, Dhaka from July 2016 to June 2017. Total 60 subjects including male and female, age ranged from 40 to 60 years were included in this study, among them 30 were non-diabetic subjects and 30 were type 2 diabetic patients. Results: In this study, mean serum TSH level was significantly (p<0.001) higher and serum FT4 level was significantly (p<0.01) lower in diabetic patients than that of apparently healthy non-diabetic subjects. Serum FT3 level was lower in type 2 diabetic patients in comparison to that of non-diabetic subjects but the difference was not statistically significant. However, among the diabetic patients 10% were subclinical hypothyroid and 6.67% were hypothyroid Conclusion: The present study reveals that hypothyroidism occurs in type 2 diabetic patients. So type 2 diabetic patients should measure thyroid hormone levels routinely to detect thyroid dysfunction. KYAMC Journal Vol. 10, No.-2, July 2019, Page 95-98


2019 ◽  
Vol 9 (1) ◽  
pp. 2-7
Author(s):  
Prabin Kumar Karki ◽  
Santosh Timalsina ◽  
Sanat Chalise ◽  
Anita Yadav ◽  
Ashish Kumar Bhattarai

Background: Diabetes mellitus has become one of the biggest health problems of this era. The resultant microvascular and macrovascular complications add to significant amount of morbidity and mortality. Urine microalbumin is considered as an early marker for microvascular compli­cations among diabetic patients. The aim of this study was to find out the prevalence of microalbuminuria among type 2 diabetic patients attending Kathmandu Medical College and its relation with glycemic control, age, sex, duration of diabetes. Methods: A total of 208 previously diagnosed type 2 diabetic patients at­tending medical outpatient department of Kathmandu Medical College, Sinamangal were included in the study over a period of 1 year (October 2017 - September 2018). Fasting and 2-hour postprandial venous blood for blood glucose and HbA1c measurement and early morning urine sam­ple (after overnight fast) was collected for detection of microalbuminuria. Statistical analysis was done using SPSS version 23. Results: The prevalence of microalbuminuria among the study population (mean age: 54.22 ± 11.76 years, mean HbA1c: 7.62 ± 1.53 %) was 42.8%. Microalbuminuria had significant correlation with HbA1c and duration of diabetes (p<0.001), but not with age, sex and type of medication. There was positive correlation between urine microalbumin and fasting and post-prandial blood glucose. Conclusions: Our present study found high prevalence of microalbumin­uria among diabetic patients with poor glycemic control. It is suggested that tighter glycemic control with regular urine microalbumin testing should be integral part of diabetic management plan to prevent long term complications such as diabetic nephropathy


2019 ◽  
Vol 31 (2) ◽  
pp. 102-104
Author(s):  
Kartick Chanda Shaha ◽  
Shima Akhter Khatun ◽  
Nafisa Mustafa ◽  
Farzana Ahmed ◽  
Mohammed Asaduzzaman Khan

Introduction:The aim of the present study was to assess the pattern of lifestyle and knowledge about diabetes mellitus among type 2 diabetic patients at two tertiary level hospitals in Mymensingh Materials and Methods: A descriptive, cross sectional study was conducted from July 2015 to December 2015 among 300 patients attending at Medicine outpatient department of the Community Based Medical College Hospital and Endocrine outpatient department of the Mymensingh Medical College Hospital after obtaining requisite consent from the patients. Data were collected through the interviewing of the patients. The collected data were entered into the computer and analyzed by using SPSS version 20.1. The study was approved by the institutional ethical committee. Results: In a pool of 300 type 2 diabetics, Most of the patients (57.3%) belonged to the middle age group 41-60 years. More than half of the respondents were female (n=223, 74.3%). 97% patients were found to have knowledge about timing of dose regimen. Majority of patient’s (35.7%) knowledge about hypoglycemia was poor. The rate of adherence to diet was 51%. The rate of adherence to exercise was 68.3%. Conclusion: Majority of type 2 DM patients displayed optimal level of diabetes knowledge. There was a high rate of non adherence to diet and exercise recommendations by patients suffering from type 2 diabetes mellitus. So continuous patient education and awareness program are required. Medicine Today 2019 Vol.31(2): 102-104


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Jamshid Vafaeimanesh ◽  
Mahmoud Parham ◽  
Mohammadreza Seyyedmajidi ◽  
Mohammad Bagherzadeh

Helicobacter pylori(HP) is a common worldwide infection with known gastrointestinal and nongastrointestinal complications. One of the gastrointestinal side effects posed for this organism is its role in diabetes and increased insulin resistance. The aim of this study was to evaluate the association betweenHPand insulin resistance in type 2 diabetic patients and nondiabetics. This cross-sectional study was carried out from May to December 2013 on 211 diabetic patients referred to diabetes clinic of Shahid Beheshti Hospital of Qom and 218 patients without diabetes.HPwas evaluated using serology method and insulin resistance was calculated using HOMA-IR. The prevalence ofH. pyloriinfection was 55.8% and 44.2% in diabetics and nondiabetics(P=0.001). The study population was divided into twoHPpositive and negative groups. Among nondiabetics, insulin resistance degree was3.01±2.12and2.74±2.18inHP+ andHP− patients, respectivelyP=0.704. Oppositely, insulin resistance was significantly higher in diabeticHP+ patients rather than seronegative ones(4.484±2.781versus3.160±2.327,P=0.013). In diabetic patients, in addition to higher prevalence ofHP, it causes a higher degree of insulin resistance.


2019 ◽  
Vol 31 (1) ◽  
pp. 19-22
Author(s):  
Kartick Chanda Shaha ◽  
Mohammed Asaduzzaman Khan ◽  
Farhana Akter ◽  
Bhagyoshree Karmokar Jyoti

Introduction: The aim of the present study was to evaluate the pattern of medication adherence to anti-diabetic drugs among type 2 diabetic patients at two tertiary level hospitals in Mymensingh. Materials and Methods: An observational, cross sectional study was conducted from January 2016 to June 2016 among patients attending at Endocrine Outpatient Department of the Mymensingh Medical College Hospital and Medicine Outpatient Department of the Community Based Medical College Hospital, after obtaining requisite consent from the patients. Once the consultation by the physician was over, the patients were interviewed. Medication adherence was assessed through the specific four questions patient questionnaire, the modified morisky instrument that has high reliability and validity and the patient was considered to be highly adherent if he or she answered in the negative to all four questions (score-0). Results: In a pool of 300 type 2 diabetics, more than half were female (n=223, 74.3%). The mean age of the patients were found to be 50.59 ± 12.57 years. Less than half (37%) of the patients were considered highly adherent, 44% patients were considered moderately adherent and 19% patients were considered poorly adherent to the prescribed anti-diabetic drugs. Conclusion: The participants in the area of study were moderately adherent to their anti-diabetic medications. Measures should be taken to improve patient’s adherence to the prescribed treatment. Medicine Today 2019 Vol.31(1): 19-22


2020 ◽  
Vol 7 (12) ◽  
pp. 1767
Author(s):  
M. D. Masum ◽  
Rajee Mahmud Talukder ◽  
Shams Ibne Maksud ◽  
Enamul Haque ◽  
Jubaida Khanam ◽  
...  

Background: Now a day erectile dysfunction (ED) and hypogonadism of the patients with type 2 diabetes mellitus (T2DM) become two common complaints. The association among hypogonadism, erectile dysfunction and type 2 diabetes of man seem to be increased. The aim of this study was to evaluate the predictors of erectile dysfunction and hypogonadism in men with types 2 diabetes mellitus (T2DM).  Methods: This was a cross-sectional study which was conducted in the Department of Shaheed Monsur Ali Medical College Hospital, Dhaka, Bangladesh Hospital, Bangladesh during the period from January 2019 to December 2019. In total 352 newly detected T2DM male patients, with complete data were finalized as the study population. All data were processed by using SPSS program version 23.0.Results: In this study, according to complement fixation test (cFT) and androgen deficiency in the aging male (ADAM) criteria, 119 (33.81%) participant had low cFT& ADAM positive under hypogonadal, 84 (23.86%) were with normal TT & ADAM negative (eugonadal), 37 (10.51%) were with low TT & ADAM negative (eugonadal), 112 (31.82%) were with normal TT & ADAM positive (eugonadal). On the other hand, according to the cFT and ADAM score in total 119 (33.81%) hypogonadal patients were with low cFT & ADAM positive. Besides this, 102 (43.78%) eugonadal patients were with normal cFT & ADAM negative and 131 (56.22%) eugonadal patients were with normal cFT & ADAM positive.Conclusions: Hence, universal screening of testosterone level and androgen deficiency symptoms is recommended in newly detected T2DM patients.


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