scholarly journals HEMODYNAMICS AND HEART RATE VARIABILITY UNDER ORTHOSTATIC CHALLENGE TEST IN YOUNG CAUCASIAN MEN: PART 1

Human Ecology ◽  
2021 ◽  
pp. 22-31
Author(s):  
A. L. Maksimov ◽  
I. V. Averyanova
2020 ◽  
Vol 11 ◽  
Author(s):  
Yukiyoshi Sumi ◽  
Chikao Nakayama ◽  
Hiroshi Kadotani ◽  
Masahiro Matsuo ◽  
Yuji Ozeki ◽  
...  

Background: Orthostatic hypotension (OH) caused by autonomic dysfunction is a common symptom in older people and patients with idiopathic rapid eye movement sleep behavior disorder (iRBD). The orthostatic challenge test is a standard autonomic function test that measures a decrease of blood pressure during a postural change from supine to standing positions. Although previous studies have reported that changes in heart rate variability (HRV) are associated with autonomic dysfunction, no study has investigated the relationship between HRV before standing and the occurrence of OH in an orthostatic challenge test. This study aims to examine the connection between HRV in the supine position and the occurrence of OH in an orthostatic challenge test.Methods: We measured the electrocardiograms of patients with iRBD and healthy older people during an orthostatic challenge test, in which the supine and standing positions were held for 15 min, respectively. The subjects were divided into three groups: healthy controls (HC), OH-negative iRBD [OH (–) iRBD], and OH-positive iRBD [OH (+) iRBD]. HRV measured in the supine position during the test were calculated by time-domain analysis and Poincaré plots to evaluate the autonomic dysfunction.Results: Forty-two HC, 12 OH (–) iRBD, and nine OH (+) iRBD subjects were included. HRV indices in the OH (–) and the OH (+) iRBD groups were significantly smaller than those in the HC group. The multivariate logistic regression analysis for OH identification for the iRBD groups showed the model whose inputs were the HRV indices, i.e., standard deviation 2 (SD2) and the percentage of adjacent intervals that varied by more than 50 ms (pNN50), had a receiver operating characteristic curve with area under the curve of 0.840, the sensitivity to OH (+) of 1.000, and the specificity to OH (–) of 0.583 (p = 0.023).Conclusions: This study showed the possibility that short-term HRV indices in the supine position would predict subsequent OH in iRBD patients. Our results are of clinical importance in terms of showing the possibility that OH can be predicted using only HRV in the supine position without an orthostatic challenge test, which would improve the efficiency and safety of testing.


2020 ◽  
Vol 8 (4) ◽  
pp. 46-66
Author(s):  
Natalia Shlyk ◽  
Alexander Alabuzhev

The aim of the study is to develop the standards of HRV indexes at rest and during an orthostatic challenge, taking into account different ranges of variability of cardiac intervals (MxDMn) of track and field athletes. The other purpose is to identify the features of changes in the standards in the training process in cases of malfunctions of cardioregulatory systems, sinus node functioning and recovery process, overtraining, and decrease in athletic performance. The authors used the results of individual dynamic express-tests of heart rate variability (HRV) in track and field athletes belonging to different specific training orientations to achieve the goals of the study. Research Methods and Organization. We carried out 1740 dynamic HRV measurements at rest and during an orthostatic challenge. The studies involved 56 track and field athletes (sprinters, middle distance runners and stayers) aged 18 to 29 years, belonging to the 1st adult category, Candidates Master of Sports and Masters of Sports, in different periods of the training process. We carried out HRV measurements in the laboratory of functional research methods of the Institute of physical culture and sports at Udmurt State University, as well as at training camps in the middle mountains (Kyrgyzstan, Kislovodsk) and on the plain (Elabuga). We examined the test subjects at rest in the morning after the previous training day, using the VARICARD 2.51 device and the ISCIM6 and VARICARD MP programs (Ryazan). We recorded cardio intervals of athletes for 5 minutes in lying position and for 6 minutes in standing position. We applied HRV measurements to one or four athletes simultaneously using the ISCIM6 and VARICARD MP programs. Research results. We assigned special emphasis to the assessment of changes in the variational range of cardiointervals (MxDMn) reflecting the state of cardiac regulation and the sinus node functioning during dynamic HRV studies in the training process of each runner. We identified seven MxDMn variation ranges from <150ms to >650ms. We revealed that each MxDMn variation range corresponds to a certain prevailing type of regulation. We demonstrated that frequent shifts of the MxDMn ranges from one level to another in the training process of runners indicate instability of cardiac regulation. We elaborated standards for the variational range of cardiointervals (MxDMn), taking into account the predominance of the HF and LF power in the HRV power spectrum for runners with different specific training orientations. We found that respiratory (HF) or vasomotor waves (LF) could prevail within the same MxDMn variation ranges, which points to a different autonomic balance. We revealed that at rest, the variational range of cardiointervals (MxDMn) depends more on the state of cardiac regulation and the sinus node functioning and less on the specifics of running. We often detected paradoxical reactions to an orthostatic challenge at low or extremely high MxDMn values in the overtrained runners. We determined that runners of any specific training orientation could increase their fitness, adaptive and reserve capabilities only in the context of the optimal regulation state, stable favorable ranges of MxDMn values, and the absence of paradoxical reactions to an orthostatic challenge. The paper contains tables with standard HRV indicators for different MxDMn variation ranges and consideration of the predominance of HF and LF waves at rest and during an orthostatic challenge, as well as examples of the results of HRV analysis at rest and during an orthostatic challenge in runners with different MxDMn variation ranges in the training process. Conclusion. The research demonstrated that the use of the HRV analysis method at rest and during an orthostatic challenge, taking into account the standards of MxDMn values in the training process of track and field athletes, is aimed at obtaining the necessary information about the stability of autonomic balance, autonomic reactivity and body reserves that ensure optimal adaptation and recovery processes.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Cody E. Dunn ◽  
Derek C. Monroe ◽  
Christian Crouzet ◽  
James W. Hicks ◽  
Bernard Choi

Abstract Heart rate variability (HRV) provides insight into cardiovascular health and autonomic function. Electrocardiography (ECG) provides gold standard HRV measurements but is inconvenient for continuous acquisition when monitored from the extremities. Optical techniques such as photoplethysmography (PPG), often found in health and wellness trackers for heart rate measurements, have been used to estimate HRV peripherally but decline in accuracy during increased physical stress. Speckleplethysmography (SPG) is a recently introduced optical technique that provides benefits over PPG, such as increased signal amplitude and reduced susceptibility to temperature-induced vasoconstriction. In this research, we compare SPG and PPG to ECG for estimation of HRV during an orthostatic challenge performed by 17 subjects. We find that SPG estimations of HRV are highly correlated to ECG HRV for both time and frequency domain parameters and provide increased accuracy over PPG estimations of HRV. The results suggest SPG measurements are a viable alternative for HRV estimation when ECG measurements are impractical.


Medicine ◽  
2017 ◽  
Vol 96 (14) ◽  
pp. e5989 ◽  
Author(s):  
Joel Rodriguez ◽  
Andrew Philip Blaber ◽  
Markus Kneihsl ◽  
Irhad Trozic ◽  
Rebecca Ruedl ◽  
...  

2019 ◽  
Vol 106 (3) ◽  
pp. 236-249 ◽  
Author(s):  
C Sachse ◽  
I Trozic ◽  
B Brix ◽  
A Roessler ◽  
N Goswami

Background Premenopausal women show a higher incidence of orthostatic hypotension than age-matched men, but there are limited data available on sex differences in cardiovascular responses to orthostatic challenge in healthy older persons. We investigated sex differences in hemodynamic and autonomic responses to orthostatic challenge in healthy older males and females. Materials and methods Fourteen older healthy women and 10 age-matched men performed a sit-to-stand test (5 min of sitting followed by 5 min of standing). A Task Force® Monitor continuously measured the following beat-to-beat hemodynamic parameters: heart rate, systolic blood pressure, diastolic blood pressure, mean blood pressure, stroke index, cardiac index, and total peripheral resistance index. Cardiac autonomic activity, low-frequency (LF: 0.04–0.15 Hz) normalized (LFnuRRI) and high-frequency (HF: 0.15–0.4 Hz) normalized (HFnuRRI) components, and the ratio between LF and HF power (LF/HF) were calculated using power spectral analysis of heart rate variability. Results Across all hemodynamic parameters, there were no significant differences between the sexes at baseline and during standing. LFnuRRI (median: 70.2 vs. 52.3, p < 0.05) and LF/HF ratio (median: 2.4 vs. 1.1, p < 0.05) were significantly higher, whereas HFnuRRI (median: 29.8 vs. 47.7, p < 0.05) was lower among women at baseline. All other heart rate variability measures did not differ between the sexes. Conclusions The data indicate that older women showed higher sympathetic and lower parasympathetic activity at rest compared to age-matched men. These results are contradictory to the observations from previous studies, which showed a reduced sympathetic and enhanced parasympathetic activity in women in all ages. Further studies are required to determine the underlying mechanisms contributing to higher incidence of orthostatic hypotension in older females.


2008 ◽  
Vol 28 (6) ◽  
pp. 384-390 ◽  
Author(s):  
Nonna Heiskanen ◽  
Heli Saarelainen ◽  
Pirjo Valtonen ◽  
Tiina Lyyra-Laitinen ◽  
Tomi Laitinen ◽  
...  

Author(s):  
Michael J. Macartney ◽  
Peter L. McLennan ◽  
Gregory E. Peoples

AbstractObjectivesHeart rate variability (HRV) is often measured during clinical and experimental cardiovascular reflex tests (CRT), as a reflection of cardiac autonomic modulation, despite limited characterization of the rapid responses that occur. Therefore, we evaluated the responsiveness of HRV indices in 20 healthy young adults (age, 27 ± 6 y; mass, 76.9 ± 16.8 kg; height, 1.79 ± 0.12 m) during four separate established CRT.MethodsThese included the [I] orthostatic challenge, [II] isometric handgrip, [III] cold pressor and [IV] cold diving reflex tests. Electrocardiogram was recorded throughout, with HRV derived from RR intervals at rest and from each CRT. On a separate day, a subgroup of participants (n=9) completed the same protocol for a second time.ResultsThe maximal slope of heart rate change (dTdt) was significantly different between all CRT, with the orthostatic challenge producing the fastest increase (2.56 ± 0.48) and the cold pressor the fastest reduction (−1.93 ± 0.68) in heart rate. Overall HRV, reflected by Poincaré plot ratio (SD1:SD2), was significantly reduced during all CRT ([I], −0.41 ± 0.12; [II], −0.19 ± 0.05; [III], −0.36 ± 0.12; [IV], −0.44 ± 0.11; p<0.05) relative to baseline and this was reproducible in time-series. However, when HRV indices were correlated to mean-RR an exponential growth-like relationship was evident (R2 ranging from: 0.52–0.62).ConclusionsThese unique outcomes demonstrate that short-term alterations in HRV are evident during CRT, while indicating the importance of adjusting for, or at least reporting, underlying heart rate when interpreting such measures.


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