scholarly journals A Case of Nontuberculous Mycobacterial Infection on Branchial Cleft Cyst

2021 ◽  
Vol 64 (7) ◽  
pp. 522-525
Author(s):  
Yu Jin Go ◽  
Sohl Park ◽  
Han Su Kim ◽  
Soo Yeon Jung
Keyword(s):  
Nontuberculous Mycobacteria ◽  
Mycobacterial Infection ◽  
Needle Aspiration ◽  
Review Of Literature ◽  
Branchial Cleft Cyst ◽  
Surrounding Environment ◽  
Pathologic Findings ◽  
Nontuberculous Mycobacterial Infection ◽  
Branchial Cleft ◽  
Cervical Area

Nontuberculous mycobacteria (NTM) is commonly found in the surrounding environment and can cause opportunistic infection. Mainly, it causes lymph node infection in the cervical area, which is often known to occur in children. Recently, we have experienced a case of NTM infection on a branchial cleft cyst in a 36-year old male. NTM was diagnosed by fine needle aspiration and branchial cleft cyst was confirmed by postoperative pathologic findings. We report this case with a review of literature.

scholarly journals Branchial cleft cyst: A case report and review of literature

2014 ◽  
Vol 18 (1) ◽  
pp. 150 ◽  
Author(s):  
Prasad Karande ◽  
Yeshwant Ingale ◽  
Surekha Chavan ◽  
Revati Deshmukh
Keyword(s):  
Case Report ◽  
Review Of Literature ◽  
Branchial Cleft Cyst ◽  
Branchial Cleft

scholarly journals Diagnostic delay of pulmonary nontuberculous mycobacterial infection in China

2014 ◽  
Vol 9 ◽  
Author(s):  
Hui Jing ◽  
Wanming Tan ◽  
Yunfeng Deng ◽  
Dachuan Gao ◽  
Liang Li ◽  
...  
Keyword(s):  
Public Health ◽  
Pulmonary Infection ◽  
Nontuberculous Mycobacteria ◽  
Diagnostic Delay ◽  
Mycobacterial Infection ◽  
Healthcare Services ◽  
Health Concern ◽  
Public Health Concern ◽  
Nontuberculous Mycobacterial Infection ◽  
Rural Patients

Background: Nontuberculous mycobacteria (NTM) infection is an emerging, but neglected public health concern in China. Findings: To investigate diagnostic delay of NTM diseases in China, we analyzed 91 patients with pulmonary NTM infection in Shandong Province. The median diagnostic delay time of the analyzed patients was 84 days, which was significantly associated with rural inhabitance (135 days vs. 73 days of urban inhabitance, p < 0.01) and lower level of first visiting hospitals/clinics (70 and 82 days of tertiary and secondary hospitals/clinics respectively vs. 120 days of primary hospitals/clinics, p < 0.05). M. farcinogenes was isolated from a 79-year-old male patient, which is the first report of pulmonary infection in humans. Conclusions: Our results indicate a significant diagnostic delay of NTM diseases in China, especially for rural patients with limited access to higher-level healthcare services.

scholarly journals Cutaneous Nontuberculous Mycobacteria Infection after Cosmetic Tattooing: A Case Report

2020 ◽  
Vol 4 (4) ◽  
pp. 379-382
Author(s):  
Jennifer Seyffert ◽  
Christopher Wong ◽  
Sadia Saeed ◽  
David Fitzmaurice
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Nontuberculous Mycobacteria ◽  
Mycobacterial Infection ◽  
Punch Biopsy ◽  
Soft Tissue Infections ◽  
Papular Eruption ◽  
Nontuberculous Mycobacterial Infection ◽  
Hispanic Male ◽  
Suppurative Inflammation

Nontuberculous (atypical) mycobacteria rarely cause skin and soft tissue infections. Tattooing with contaminated gray ink has been implicated in previously reported outbreaks. We report the case of a 39-year-old Hispanic male who presented with a refractory, pruritic, papular eruption within the distribution of his tattoo with punch biopsy demonstrating papillary dermal granulomatous and suppurative inflammation surrounding small collections of acid-fast bacilli with associated superficial and deep dermal perivascular lymphatic inflammation, consistent with nontuberculous mycobacterial infection. Although uncommon, clinicians should consider nontuberculous mycobacterial infection in the differential diagnosis of refractory tattoo-associated skin eruptions.

scholarly journals Branchial cleft cyst - A case report with review of literature

2014 ◽  
Vol 6 (2) ◽  
pp. 125 ◽  
Author(s):  
Mamatha Boringi ◽  
Milanjeet Kaur ◽  
Arshia Shireen ◽  
SharathChandra Bontha
Keyword(s):  
Case Report ◽  
Review Of Literature ◽  
Branchial Cleft Cyst ◽  
Branchial Cleft

scholarly journals Type II First Branchial Cleft Cyst: A Case Report with Review of Literature

2011 ◽  
Vol 63 (S1) ◽  
pp. 75-77 ◽  
Author(s):  
K. G. Somashekara ◽  
K. G. Sudarshan Babu ◽  
S. Lakshmi ◽  
V. Geethamani ◽  
R. G. Yashaswi ◽  
...  
Keyword(s):  
Case Report ◽  
Type Ii ◽  
Review Of Literature ◽  
Branchial Cleft Cyst ◽  
Branchial Cleft

scholarly journals Type I second branchial cleft cyst in an adult patient

2021 ◽  
Vol 8 (10) ◽  
pp. 3217
Author(s):  
Ramesh M. Tambat ◽  
Nitish A. Golasangi ◽  
Siddesh G. B. ◽  
Suhas P. ◽  
Yogendra Shrestha ◽  
...  
Keyword(s):  
Significant Risk ◽  
Neck Region ◽  
Rare Condition ◽  
Needle Aspiration ◽  
Type I ◽  
Branchial Cleft Cyst ◽  
Patient Reported ◽  
Branchial Cleft Anomalies ◽  
Second Branchial Cleft Cyst ◽  
Branchial Cleft

Branchial cleft anomalies are rare diseases of head and neck region. Second branchial cleft anomalies represent more than 95% of all branchial cleft anomalies. Second branchial cleft cyst is a benign developmental cyst due to the incomplete obliteration of pharyngeal cleft. A 46-year-old female patient reported to hospital with a complaint of swelling over the left side of the neck since 4 to 5 months. On clinical examination, swelling was seen below and behind the angle of mandible on the left side. The patient was evaluated using ultrasound and contrast enhanced computerized tomography (CECT) of neck which revealed second left bronchial cleft cyst/enlarged cystic lymph-node. Fine needle aspiration cytology of the swelling showed features of cystic lesion. Type-I branchial cleft cyst is a rare condition with a significant risk of misdiagnosis. To avert misdiagnosis and surgical complications, thorough investigation must be performed prior to surgical intervention.

p53 Immunolocalization in Cell Block Preparations of Squamous Lesions of the Neck: An Adjunct to Fine-Needle Aspiration Diagnosis of Malignancy

1999 ◽  
Vol 123 (5) ◽  
pp. 421-425
Author(s):  
Kamal K. Khurana ◽  
Ibrahim Ramzy ◽  
Luan D. Truong
Keyword(s):  
Fine Needle Aspiration ◽  
P53 Protein ◽  
Needle Aspiration ◽  
Protein Accumulation ◽  
Branchial Cleft Cyst ◽  
Cytologic Diagnosis ◽  
Fine Needle ◽  
Squamous Cells ◽  
Branchial Cleft

Abstract Objective.—Mutations of the p53 tumor suppressor gene, with consequent nuclear p53 protein accumulation, are among the most common genetic abnormalities in human cancers. The purpose of this study was to determine the utility of p53 immunostaining as an adjunct to the diagnosis of malignancy in fine-needle aspirations of squamous lesions of the neck. Materials and Methods.—Using a monoclonal antibody to the p53 protein and a standard avidin-biotin complex technique, immunostaining was performed on paraffin-embedded cell blocks of 20 cases with the following cytologic diagnoses: (1) metastatic squamous cell carcinoma (SCC) (7 cases); (2) atypical squamous cells, SCC cannot be excluded (7 cases); and (3) cytologic findings consistent with branchial cleft cyst (6 cases). Tissue or clinical follow-up was available in all cases. Results.—Five (71%) of 7 cases with an unequivocal cytologic diagnosis of metastatic SCC were positive for p53 protein. Tissue follow-up confirmed metastatic SCC in all of these 7 cases. Of the 7 cases with cytologic diagnosis of atypical squamous cells, 2 were negative and 5 (71%) were positive for p53 protein. Subsequent excisional biopsies in these cases revealed metastatic SCC (6 cases) and branchial cleft cyst (1 case). The squamous cells in all 5 cases with cytologic findings consistent with branchial cleft cyst were negative for p53 protein; tissue follow-up confirmed the diagnoses of branchial cleft cyst in 4 cases. In the remaining 2 cases excision was not performed, as the cystic lesion was completely decompressed and, clinically, no recurrences were identified at 14 and 8 months of follow-up. Conclusions.—Our findings suggest that p53 immunostaining is helpful in differentiating benign and malignant squamous lesions. While negative staining for p53 does not exclude malignancy, positive immunostaining may aid in accurate fine-needle aspiration diagnosis of malignancy in cytomorphologically equivocal squamous lesions of the neck.

scholarly journals Anti-CD20 (rituximab) therapy for anti–IFN-γ autoantibody–associated nontuberculous mycobacterial infection

Blood ◽  
2012 ◽  
Vol 119 (17) ◽  
pp. 3933-3939 ◽  
Author(s):  
Sarah K. Browne ◽  
Rifat Zaman ◽  
Elizabeth P. Sampaio ◽  
Kamonwan Jutivorakool ◽  
Lindsey B. Rosen ◽  
...  
Keyword(s):  
Therapeutic Response ◽  
Nontuberculous Mycobacteria ◽  
Mycobacterial Infection ◽  
First Year ◽  
Intracellular Pathogens ◽  
Refractory Disease ◽  
Disease Remission ◽  
Nontuberculous Mycobacterial Infection ◽  
Ifn Γ ◽  
Anti Cd20

Abstract Patients with anti–IFN-γ autoantibodies have impaired IFN-γ signaling, leading to severe disseminated infections with intracellular pathogens, especially nontuberculous mycobacteria. Disease may be severe and progressive, despite aggressive treatment. To address the underlying pathogenic IFN-γ autoantibodies we used the therapeutic monoclonal rituximab (anti-CD20) to target patient B cells. All subjects received between 8 and 12 doses of rituximab within the first year to maintain disease remission. Subsequent doses were given for relapsed infection. We report 4 patients with refractory disease treated with rituximab who had clinical and laboratory evidence of therapeutic response as determined by clearance of infection, resolution of inflammation, reduction of anti–IFN-γ autoantibody levels, and improved IFN-γ signaling.

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