scholarly journals Assessment of perioperative antibiotic prophylaxis for gynecological surgeries at an academic hospital in Brazil

2021 ◽  
Vol 10 (8) ◽  
pp. e30810817299
Author(s):  
Denise Ramos dos Santos ◽  
Milene Rangel da Costa

The aim of this study was to assess the adequacy of physicians' practice patterns regarding the use of perioperative antibiotic prophylaxis for gynecological surgeries in an academic hospital specialized in gynecology located at Rio de Janeiro city, Brazil. This is a retrospective study assessing all gynecological surgeries performed over one year. Appropriateness of antibiotic prophylaxis was determined according to criteria adapted from evidence-based guidelines. Clinical practice regarding the use of perioperative antibiotic prophylaxis was considered appropriate for 58.4% of 416 surgeries. The non-indicated use of antimicrobial prophylaxis was the main factor determining the low percentage of overall adequacy. Three variables were independently associated with inappropriate administration of perioperative antibiotics: patients age, breast surgeries and longer procedures. Antibiotic prophylaxis compliance to published recommendations is low. Women undergoing gynecological surgery are exposed to unnecessary risks associated to non-indicated use of antibiotic prophylaxis. Strategies aimed to improve compliance to evidence-based guidelines are necessary.

2012 ◽  
Vol 3 (1) ◽  
pp. 74-76
Author(s):  
Frieda A Pickett

ABSTRACT Issues related to clinical decision-making regarding prescribing antibiotic prophylaxis prior to oral procedures for the client with a prosthetic joint are discussed. Method PubMed and relevant professional guidelines were searched for research and for evidence-based guidelines. Outcome There is a need for evidence-based guidelines developed by stakeholders including the American Academy of Orthopedic Surgeons, the American Dental Association and the Infectious Disease Society. There is an absence of level 1 evidence for or against the use of prophylactic antibiotics in patients with prosthetic joints undergoing invasive dental treatment. Therefore, until the professional organizations provide evidence-based guidance, professional judgment must depend on the client history following joint replacement and the state of the host immune response. How to cite this article Pickett FA. Issues in Professional Judgment: Antibiotic Prophylaxis in Client with Prosthetic Joint. World J Dent 2012;3(1):74-76.


2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Anna Abate ◽  
Giulia Querques ◽  
Riccardo Giovanazzi ◽  
Camillo Di Bella ◽  
Valeria Besostri ◽  
...  

We report the case of a 45-year-old woman with a slow-growing palpable nodule on the left breast, confirmed as a well-defined opacity on mammography, corresponding to a 5 cm hyperechoic lesion on ultrasound, and considered, on the basis of clinical examination and radiological findings, to be consistent with a lipoma. One year later, the patient represented with an enlarged left breast mass and underwent further imaging investigation with subsequent diagnosis of primary breast angiosarcoma obtained via a Vacuum-Assisted Breast Biopsy. The patient developed metastatic disease and succumbed to the disease one year after definitive diagnosis. Primary breast angiosarcoma is a rare malignant vascular neoplasia, characterized by aggressive patterns, poor prognosis, and absence of pathognomonic radiological features. Currently, there are no evidence-based guidelines regarding treatment, even though wide surgical resection followed by chemo- and radiotherapy appears to improve survival.


2008 ◽  
Vol 29 (12) ◽  
pp. 1164-1166 ◽  
Author(s):  
Philip J. B. Davis ◽  
Donald Spady ◽  
Chris de Gara ◽  
Sarah E. D. Forgie

We surveyed 589 surgeons in Alberta, Canada, about the prevention of surgical site infections and compared their practices to the recommendations of evidence-based guidelines. Of the 247 (42%) who responded, most (156 [63%]) were not in compliance with guideline recommendations for preoperative bathing, hair removal, antimicrobial prophylaxis, or intraoperative skin preparation (although 91 [37%] state they are following guidelines).


2017 ◽  
Vol 56 (2) ◽  
Author(s):  
Alexia Anagnostopoulos ◽  
Daniel A. Bossard ◽  
Bruno Ledergerber ◽  
Patrick O. Zingg ◽  
Annelies S. Zinkernagel ◽  
...  

ABSTRACTIf a bone or joint infection is suspected, perioperative antibiotic prophylaxis is frequently withheld until intraoperative microbiological sampling has been performed. This practice builds upon the hypothesis that perioperative antibiotics could render culture results negative and thus impede tailored antibiotic treatment of infections. We aimed to assess the influence of antibiotic prophylaxis within 30 to 60 min before surgery on time to positivity of microbiological samples and on proportion of positive samples inCutibacterium acnesbone and joint infections. Patients with at least one sample positive forC. acnesbetween January 2005 and December 2015 were included and classified as having an “infection” if at least 2 samples were positive; otherwise they were considered to have a sample “contamination.” Kaplan-Meier curves were used to illustrate time to culture positivity. We found 64 cases with aC. acnesinfection and 46 classified as having aC. acnescontamination. Application of perioperative prophylaxis significantly differed between the infection and contamination groups (72.8% versus 55.8%;P< 0.001). Within the infection group, we found no difference in time to positivity between those who had or had not received a perioperative prophylaxis (7.07 days; 95% confidence interval [CI], 6.4 to 7.7, versus 7.11 days; 95% CI, 6.8 to 7.5;P= 0.3). Also, there was no association between the proportion of sample positivity and the application of perioperative prophylaxis (71.6% versus 65.9%;P= 0.39). Since perioperative prophylaxis did not negatively influence the microbiological yield inC. acnesinfections, antibiotic prophylaxis can be routinely given to avoid surgical site infections.


2015 ◽  
Vol 63 (4) ◽  

“Tennis and golfer’s elbow” are common pathologies due to overload of forearm extensors and flexors, and actually occur mostly outside tennis and golf sports. Several differential diagnoses of medial and lateral epicondylitis have to be excluded as there are a number of other conditions with similar clinical symptoms. The high rate of spontaneous recovery has to be considered in treatment. Evidence based conservative treatment comprises excentric physiotherapy, local injections, and physical methods. Surgery is reserved for patients with persistence of symptoms for more than one year despite non-surgical treatment.


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