scholarly journals CD4+/CD8+ T lymphocytes imbalance in children with severe 2009 pandemic influenza A (H1N1) pneumonia

2011 ◽  
Vol 54 (5) ◽  
pp. 207 ◽  
Author(s):  
Ji Eun Kim ◽  
Siegfried Bauer ◽  
Kyong Suk La ◽  
Kee Hyoung Lee ◽  
Ji Tae Choung ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Cd8 T Lymphocytes ◽  
Influenza A H1n1 ◽  
H1n1 Pneumonia

scholarly journals Mortality and severity evaluation by routine pneumonia prediction models among Japanese patients with 2009 pandemic influenza A (H1N1) pneumonia

2014 ◽  
Vol 52 (5) ◽  
pp. 280-287 ◽  
Author(s):  
Yuji Fujikura ◽  
Shuichi Kawano ◽  
Yuji Kouzaki ◽  
Masahiro Shinoda ◽  
Yu Hara ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
Prediction Models ◽  
Japanese Patients ◽  
Influenza A H1n1 ◽  
H1n1 Pneumonia

Clinical Characteristics of 2009 Pandemic Influenza A (H1N1) Pneumonia in Atopic versus Non-atopic Children

2012 ◽  
Vol 22 (1) ◽  
pp. 78
Author(s):  
Mi Ju ◽  
Jin Young Shin ◽  
Kye Hyang Lee ◽  
Hye Jin Park ◽  
Kyung Hoon Lee ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
Clinical Characteristics ◽  
Influenza A H1n1 ◽  
H1n1 Pneumonia

scholarly journals Early recognition of the 2009 pandemic influenza A (H1N1) pneumonia by chest ultrasound

Critical Care ◽  
2012 ◽  
Vol 16 (1) ◽  
pp. R30 ◽  
Author(s):  
Americo Testa ◽  
Gino Soldati ◽  
Roberto Copetti ◽  
Rosangela Giannuzzi ◽  
Grazia Portale ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
Early Recognition ◽  
Chest Ultrasound ◽  
Influenza A H1n1 ◽  
H1n1 Pneumonia

scholarly journals Evaluation of Pandemic Influenza A (H1N1) Pneumonia Patients Followed up in Intensive Care Unit from the Perspective of COVID-19

2021 ◽  
Vol 05 (02) ◽  
Author(s):  
Pakize Ozciftci Yilmaz ◽  
Barcin Ozturk ◽  
Ali Riza Kagnici ◽  
Mustafa Deniz ◽  
Ali Ihsan Sert ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Influenza A H1n1 ◽  
H1n1 Pneumonia

scholarly journals Expression of Surfactant protein D (SP-D) distinguishes severe pandemic influenza A(H1N1) from COVID-19

2021 ◽  
Author(s):  
José Alberto Choreño-Parra ◽  
Luis Armando Jiménez-Álvarez ◽  
Gustavo Ramírez-Martínez ◽  
Alfredo Cruz-Lagunas ◽  
Mahima Thapa ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
Alveolar Epithelium ◽  
Surfactant Protein ◽  
High Serum ◽  
Surfactant Protein D ◽  
Diagnostic Challenge ◽  
Moderate Disease ◽  
Influenza A H1n1 ◽  
Novel Biomarkers

Abstract The differentiation of influenza and COVID-19 could constitute a diagnostic challenge during the ongoing winter due to their clinical similitude. Thus, novel biomarkers that enable distinguishing both diseases are required. Here, we evaluated whether the surfactant protein D (SP-D), a collectin produced at the alveolar epithelium with known immune properties, was useful to differentiate pandemic influenza A(H1N1) from COVID-19 in critically ill patients. Our results revealed high serum SP-D levels in severe pandemic influenza but not COVID-19 patients. This finding was validated in a separate cohort of mechanically ventilated COVID-19 patients who also showed low plasma SP-D levels. However, plasma SP-D levels did not distinguish seasonal influenza from COVID-19 in mild-to-moderate disease. Finally, we found that high serum SP-D levels were associated with mortality and renal failure among severe pandemic influenza cases. Thus, our studies have identified SP-D as a unique biomarker expressed during severe pandemic influenza but not COVID-19.

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