scholarly journals Unilateral Facial Palsyin Guillain–Barré Syndrome, A Hyperreflexic Variant Case

EMJ Neurology ◽  
2020 ◽  
pp. 115-121
Author(s):  
Muhammad Sohaib Asghar ◽  
Abubakar Tauseef ◽  
Maryam Zafar ◽  
Syed Anosh Ali Naqvi ◽  
Uzma Rasheed ◽  
...  
Keyword(s):  
Clinical Features ◽  
Facial Palsy ◽  
Western Hemisphere ◽  
Common Variant ◽  
Guillain Barre Syndrome ◽  
Atypical Presentation ◽  
Diagnostic Challenge ◽  
Motor Weakness ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Guillain–Barré syndrome (GBS) is a form of rapidly progressive, acute inflammatory demyelinating polyradiculopathy. Acute inflammatory demyelinating polyradiculopathy is the most common variant of GBS, especially in the western hemisphere. It is diagnosed without hesitation when it presents with its characteristic clinical features of ascending paralysis and areflexia. It is when an atypical presentation appears, with brisk or very brisk reflexes, that diagnosis becomes difficult. In this case, a patient who presented with progressive motor weakness, unilateral facial palsy, and hyperreflexia on examination is described in order to demonstrate a variant of GBS and its management. Keeping in mind that the management of the disease does not change with the variant, the diagnostic challenge that is put forward by those variants needs a focussed approach by physicians.

scholarly journals Guillain-Barré syndrome triggered by surgery in a Chinese population: a multicenter retrospective study

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Qiaoyu Gong ◽  
Shuping Liu ◽  
Yin Liu ◽  
Jiajia Yao ◽  
Xiujuan Fu ◽  
...  
Keyword(s):  
Clinical Features ◽  
Orthopedic Surgery ◽  
Southern China ◽  
Axonal Neuropathy ◽  
Trigger Factor ◽  
Guillain Barre Syndrome ◽  
Initial Symptoms ◽  
Guillain Barré Syndrome ◽  
Potential Trigger ◽  
Guillain Barré

Abstract Background Surgery is a potential trigger of Guillain-Barré syndrome (GBS), a disorder which leads to an autoimmune-mediated attack of peripheral nerves. The present study was designed to explore clinical features of post-surgical GBS compared with those of general GBS in order to provide better clinical advice to patients undergoing surgery. Methods The medical records of GBS patients who were seen at 31 tertiary hospitals in southern China between January 1, 2013 and September 30, 2016 were retrospectively analyzed. Post-surgical GBS was defined as symptoms of GBS within 6 weeks after surgery. Clinical features of post-surgical GBS are described and are compared with general GBS. Results Among the 1001 GBS patient cases examined in this study, 45 (4.5%) patient cases exhibited symptoms of GBS within 6 weeks of undergoing surgery. Within this group, 36 (80.0%) patients developed initial symptoms of limb weakness. The average interval between surgery and symptom onset was 13.31 days. The most common type of surgery which triggered GBS was orthopedic surgery, followed by neurological surgery. Compared to general GBS, post-surgical GBS was characterized by a higher proportion of severe patients (Hughes functional grading scale (HFGS) score ≥ 3) upon admission and at nadir, higher HFGS scores at discharge, and longer hospital stays. Post-surgical GBS patients also had a significantly higher frequency of the acute motor axonal neuropathy subtype (37.9 vs. 14.2, respectively; P = 0.001). Conclusion Surgery is probably a potential trigger factor for GBS, especially orthopedic surgery. Infections secondary to surgery may play a role. The possibility of preceding (post-operative) infections was not excluded in this study. Clinical presentation of post-surgical GBS is characterized by a more severe course and poorer prognosis, and should be closely monitored. Trial registration chicTR-RRc-17,014,152.

scholarly journals Clinical features and prognosis with Guillain-Barré syndrome

2011 ◽  
Vol 14 (2) ◽  
pp. 98 ◽  
Author(s):  
Sinan Akbayram ◽  
Cihangir Akgün ◽  
Refah Sayin ◽  
Mehmet-Selçuk Bektas ◽  
Murat Dogan ◽  
...  
Keyword(s):  
Clinical Features ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals Guillain-Barre syndrome- Rationale for physiotherapy management of the acute severe patient

1996 ◽  
Vol 52 (4) ◽  
pp. 85-87 ◽  
Author(s):  
Lynn Fearnhead ◽  
Vivian U. Fritz
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Supportive Care ◽  
Clinical Features ◽  
Guillain Barre Syndrome ◽  
Critical Importance ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Severe Patient

The critical importance of supportive care including physiotherapy to the acute severe Guillain-Barre patient is emphasised in numerous reports in the literature. However, there are no systematic studies of physiotherapy in Guillain-Barre syndrome (GBS). This article examines the aetiology, pathology, clinical features, prognosis and treatment of GBS with reference to the physiotherapists’ management of the acute severe patient treated in an intensive care unit.

HyperCKemia in Guillain-Barré Syndrome

2020 ◽  
Vol 83 (4) ◽  
pp. 415-420
Author(s):  
Seok-Jin Choi ◽  
Yoon-Ho Hong ◽  
Jun-Soon Kim ◽  
Je-Young Shin ◽  
Jung-Joon Sung
Keyword(s):  
Creatine Kinase ◽  
South Korea ◽  
Clinical Features ◽  
Serum Creatine Kinase ◽  
Guillain Barre Syndrome ◽  
Teaching Hospitals ◽  
Fisher Syndrome ◽  
Guillain Barré Syndrome ◽  
Male Sex ◽  
Guillain Barré

The aim of the present study was to investigate the frequency and clinical features of Guillain-Barré syndrome (GBS) with hyperCKemia. We retrospectively identified 139 patients with GBS at 2 teaching hospitals in South Korea. We excluded patients with Miller-Fisher syndrome (n = 19), acute bulbar palsy (n = 3), and those whose serum creatine kinase (CK) levels were not measured (n = 45). Twelve of 72 patients (16.7%) had transient hyperCKemia, defined as serum CK ≥300 IU/L. The frequency of male sex and non-demyelinating electrodiagnostic features were higher in patients with hyperCKemia than those without. Transient hyperCKemia, occasionally seen in patients with GBS may be associated with the non-demyelinating subtype.

scholarly journals Acute neuromuscular weakness associated with dengue infection

2012 ◽  
Vol 03 (01) ◽  
pp. 36-39 ◽  
Author(s):  
Harmanjit Singh Hira ◽  
Amandeep Kaur ◽  
Anuj Shukla
Keyword(s):  
Dengue Virus ◽  
Dengue Infection ◽  
Neurological Complications ◽  
Electrolyte Imbalance ◽  
Guillain Barre Syndrome ◽  
Motor Weakness ◽  
Presenting Symptoms ◽  
Guillain Barré Syndrome ◽  
Serotype 1 ◽  
Guillain Barré

ABSTRACT Background: Dengue infections may present with neurological complications. Whether these are due to neuromuscular disease or electrolyte imbalance is unclear. Materials and Methods: Eighty-eight patients of dengue fever required hospitalization during epidemic in year 2010. Twelve of them presented with acute neuromuscular weakness. We enrolled them for study. Diagnosis of dengue infection based on clinical profile of patients, positive serum IgM ELISA, NS1 antigen, and sero-typing. Complete hemogram, kidney and liver functions, serum electrolytes, and creatine phosphokinase (CPK) were tested. In addition, two patients underwent nerve conduction velocity (NCV) test and electromyography. Results: Twelve patients were included in the present study. Their age was between 18 and 34 years. Fever, myalgia, and motor weakness of limbs were most common presenting symptoms. Motor weakness developed on 2 nd to 4 th day of illness in 11 of 12 patients. In one patient, it developed on 10 th day of illness. Ten of 12 showed hypokalemia. One was of Guillain-Barré syndrome and other suffered from myositis; they underwent NCV and electromyography. Serum CPK and SGOT raised in 8 out of 12 patients. CPK of patient of myositis was 5098 IU. All of 12 patients had thrombocytopenia. WBC was in normal range. Dengue virus was isolated in three patients, and it was of serotype 1. CSF was normal in all. Within 24 hours, those with hypokalemia recovered by potassium correction. Conclusions: It was concluded that the dengue virus infection led to acute neuromuscular weakness because of hypokalemia, myositis, and Guillain-Barré syndrome. It was suggested to look for presence of hypokalemia in such patients.

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