scholarly journals Leukocyte Profile in Experimental Animals in Modeling a Wound Process Under Low Altitude Conditions and in the Period of Deadaptation to High Altitude

2020 ◽  
Vol 6 (11) ◽  
pp. 235-241
Author(s):  
B. Niyazov ◽  
Zh. Mamakeev ◽  
A. Sabitov ◽  
N. Mamanov

The article presents the leukocyte profile in experimental animals during the modeling of the wounded process in the conditions of low mountains and during the period of maladjustment to the high mountains. The animals were divided into 3 series: Series I — control series, permanently living in the conditions of Bishkek; Series II — an experimental series, after a 3-day stay at the experimental high-mountain base of the KSMA named after I. K. Akhunbaev as part of the Central Scientific Research Laboratory, moved to the conditions of Bishkek with subsequent modeling and monitoring of the course of the wound process; III series — an experimental series, after a 30-day stay at the experimental high-mountain base of the KSMA named after I. K. Akhunbaev as part of the Central Scientific Research Laboratory, moved to the conditions of Bishkek, followed by modeling and monitoring the course of the wound process. The analysis of the obtained leukograms shows that in the group of purulent inflammation during the period of maladjustment to the highlands after a short stay in the mountains, on the 3rd day of the study, leukocytosis is noted, during the study, a decrease in this indicator was noted and on the 30th day did not reach the norm.

2020 ◽  
Vol 6 (11) ◽  
pp. 226-234
Author(s):  
B. Niyazov ◽  
Zh. Mamakeev ◽  
A. Sabitov ◽  
N. Mamanov

The article presents the dynamics of the content of IL-1β and IL-10 in blood plasma in experimental animals when modeling a wounded process in low mountains and during the period of de-adaptation to high mountains while modeling a wounded process in conditions of low mountains and during a period of de-adaptation to high mountains. Animals were divided into 3 series: Series I — control series, permanently living in the conditions of Bishkek; II series — an experimental series, after a 3-day stay at the experimental high-mountain base of the KSMA named after I.K. Akhunbaev as part of the Central Scientific Research Laboratory, moved to the conditions of Bishkek with subsequent modeling and monitoring of the course of the wound process; III series - an experimental series, after a 30-day stay at the experimental high-mountain base of the KSMA named after I.K. Akhunbaev as part of the Central Scientific Research Laboratory, moved to the conditions of Bishkek, followed by modeling and monitoring the course of the wound process. Analysis of the data obtained shows that during aseptic inflammation, the opposite dynamics of the production of one of the key interleukins, with IL-1β, with a maximum concentration 12 hours after the onset of aseptic inflammation, was observed. The revealed changes in the content of cytokines during experimental aseptic inflammation determined the timely change and adequate duration of cellular reactions. In purulent inflammation, the dynamics of cytokine secretion was unidirectional, which led to a delay in all cellular phases of the inflammatory process. During the period of deadaptation after a long stay in high mountains, there is a low secretion of IL-1 and 10, associated with the depletion of protective and adaptive mechanisms.


2020 ◽  
Vol 4 (10) ◽  
Author(s):  
Dan Zhao

With the continuous investment of scientific research funds, the hardware conditions of many scientific research laboratories in Colleges and universities have been widely constructed and developed. The share of instruments in scientific research laboratories has been increasing, and the problems in the management of instruments have gradually emerged. Therefore, more and more colleges and universities pay attention to the maximum benefit of scientific research instruments and equipment and the importance of discussing the management of instruments and equipment. This paper discusses and analyzes the problems existing in the management of instruments and equipment in the scientific research laboratory, and puts forward the problems and solutions to improve the management of experimental instruments and equipment in Colleges and universities in the new era.


1963 ◽  
Vol 9 ◽  
pp. 183-204 ◽  

Probably to the great majority of English speaking people, the expression ‘O.M .’ has no very definite connotation. Certainly no strong feeling of affection, no marked sense of loyalty, is conjured up by saying ‘O.M .’. Yet for more than thirty years, in almost every scientific research laboratory in Canada, ‘O.M .’ had one well-known and very definite meaning: Otto Maass. The expression was used not frivolously, but with a sense of very real esteem and affection. It is, of course, not uncommon for young men to refer to their chiefs as ‘the Master’, ‘the King’, etc. whether these chiefs be artists or generals, directors of academic research laboratories or directors of theatrical productions. Such nicknames usually have a variety of connotations, but among Maass’s former students, the intense loyalty and depth of feeling of personal friendship that were implied by ‘O.M .’ was quite exceptional. While Dr Maass’s contributions to Canadian science and to Canada’s war effort were indeed remarkable, perhaps even more remarkable was the highly personal and enduring character of the veneration which he inspired in his students and close associates.


1986 ◽  
Vol 79 (1) ◽  
pp. 7-8
Author(s):  
Arthur Luehrmann

Ask your fellow citizens what a computer is, and guess what you will hear. “A giant calculator,” “A number cruncher.” “A machine that does math very fast.” And so on. In the minds of most people, the modern computer is tied closely to the world of arithmetic. Yet most electronic computers hardly do arithmetic at all. About a dozen years ago, a study at a major scientific research laboratory aimed at finding out what fraction of the time its giant “number cruncher” actually did arithmetic. Only 5 percent of the time involved adding, subtracting, multiplying, and dividing numbers. The other 95 percent involved the moving of information from place to place, testing for logical truth, and counting. In actual practice today, a computer is an information machine, not an arithmetic machine.


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