scholarly journals Brain Neurogenetics: Human Sleep and Longevity

2021 ◽  
Vol 7 (3) ◽  
pp. 93-135
Author(s):  
A. Volobuev ◽  
N. Romanchuk ◽  
S. Bulgakova

Human brains are biological, biophysical, neurophysiological and medico-social paradigms of information exchange. Modern communications are multilevel, multi-paradigm and interdisciplinary models of information exchange. The new competencies of psychoneuroimmunoendocrinology and psychoneuroimmunology play a strategic role in interdisciplinary science and interdisciplinary planning and decision-making. The introduction of multi-vector neurotechnologies of artificial intelligence and the principles of digital health care will contribute to the development of modern neuroscience and neuromarketing. Neurogenetics is a center for multidisciplinary and interdisciplinary research using advanced methods, with the participation of 5P Medicine and 5G technology. Human genome sequencing was an important scientific milestone that revolutionized biology and medicine. The Human Genome Project is a neurogenetic routing from the 20th to the 21st century, numerous discoveries due to the collaboration between discerning clinicians and technically innovative fundamental scientists. Genomic engineering, genome editing and gene editing refer to modifications (inserts, deletions, substitutions) in the genome of a living organism. Modern genome editing is based on clustered regularly alternating short palindromic repeats and associated protein 9 (CRISPR-Cas9). In prokaryotes, CRISPR-Cas9 is an adaptive immune system that naturally protects cells from viral DNA infections. CRISPR-Cas9 has been modified to create a universal genome editing technology that has a wide range of applications in medicine, agriculture and basic gene function research. sleep is the main tool and mechanism in the formation of cognitive memory, its quantitative and qualitative volume, the integration of the transition to a qualitatively new level of self-development and self-improvement, which allows you to create a new intellectual “qualifying mind”. The 21st century Homo sapiens will have the ability to understand physiological and neurophysiological sleep patterns, manage and change their sleep habits. Digitization of sleep is the future for the development of industry, health, science and personalized health.

Biomolecules ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 90
Author(s):  
Ryuji Hamamoto

The Human Genome Project, completed in 2003 by an international consortium, is considered one of the most important achievements for mankind in the 21st century [...]


2020 ◽  
Author(s):  
André De Faria Pereira Neto ◽  
Leticia Barbosa ◽  
Rodolfo Paolucci

UNSTRUCTURED Billions of people in the world own a smartphone. It is a low-cost, portable computing device with countless features, among which applications stand out, which are programs or software developed to meet a specific goal. A wide range of applications available ranging from entertainment and personal organization to work and education is available currently. It is a vast and profitable market. Health applications have been a means of intervention for different areas, including chronic diseases, epidemics, and health emergencies. A recently published paper in the journal with the highest impact factor in Digital Health (“Journal of Medical Internet Research”) proposes a classification of health applications. This study performs a critical analysis of this organization and presents other sort criteria. This paper also presents and analyzes the “Meu Info Saúde” (“My Health Info”) app – a pioneering government initiative focused on primary care launched by the Oswaldo Cruz Foundation. The application classification proposal that will be presented builds on the intervention strategies in the health-disease process, namely: “Health Promotion”, “Disease Prevention” and “Care, Treatment and Rehabilitation”, as defined by official documents such as the World Health Organization and the Centers for Disease Control and Prevention. Most applications present in the sample are of private and foreign origin, free to download, but with a display of ads or the sale of products and services. The sampled applications were classified as “Health Promotion”, and some applications have also been categorized as “Disease Prevention” or “Care, Treatment or Rehabilitation” because they have multiple functionalities. The applications identified as “Health Promotion” focused only on individuals’ lifestyle and their increased autonomy and self-care management capacity. From this perspective, the apps analyzed in this paper differ from the “Meu Info-Saúde” application developed at Fiocruz.


Author(s):  
Gesa Busch ◽  
Erin Ryan ◽  
Marina A. G. von Keyserlingk ◽  
Daniel M. Weary

AbstractPublic opinion can affect the adoption of genome editing technologies. In food production, genome editing can be applied to a wide range of applications, in different species and with different purposes. This study analyzed how the public responds to five different applications of genome editing, varying the species involved and the proposed purpose of the modification. Three of the applications described the introduction of disease resistance within different species (human, plant, animal), and two targeted product quality and quantity in cattle. Online surveys in Canada, the US, Austria, Germany and Italy were carried out with a total sample size of 3698 participants. Using a between-subject design, participants were confronted with one of the five applications and asked to decide whether they considered it right or wrong. Perceived risks, benefits, and the perception of the technology as tampering with nature were surveyed and were complemented with socio-demographics and a measure of the participants’ moral foundations. In all countries, participants evaluated the application of disease resistance in humans as most right to do, followed by disease resistance in plants, and then in animals, and considered changes in product quality and quantity in cattle as least right to do. However, US and Italian participants were generally more positive toward all scenarios, and German and Austrian participants more negative. Cluster analyses identified four groups of participants: ‘strong supporters’ who saw only benefits and little risks, ‘slight supporters’ who perceived risks and valued benefits, ‘neutrals’ who showed no pronounced opinion, and ‘opponents’ who perceived higher risks and lower benefits. This research contributes to understanding public response to applications of genome editing, revealing differences that can help guide decisions related to adoption of these technologies.


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