scholarly journals Functional and metabolic disorders in patients with cholelithiasis after undergone cholecystectomy

2020 ◽  
Vol 4 (38) ◽  
pp. 37-43
Author(s):  
S. V. Tikhonov ◽  
V. D. Dekkanova ◽  
N. V. Bakulina ◽  
M. D. Korzheva ◽  
M. A. Kalinina

The article describes the results of a clinical observational study of patients with cholelithiasis after cholecystectomy. The article is about the metabolic disorders in patients with gallstone disease, the mechanisms of development of functional and metabolic disorders after cholecystectomy. Particular attention is paid to the genetic, hormonal mechanisms, the role of microbiota and bile acids.

Author(s):  
S. Yu. Matalayeva

The article provides current information on comorbid diseases in both adults and children with cholelithiasis. It describes their pathogenetic relationship with the formation of gallstones. The authors highlight the causal factors in the development of both gallstone disease and accompanying comorbid conditions. They demonstrate the generality of metabolic disorders in cholelithiasis and metabolic syndrome. The article describes the mechanisms of formation of both cholesterol and pigmented gallstones, which can be formed against the background of both somatic and infectious diseases. The article shows the role of drugs in the formation of gallstones. The authors substantiate the necessity of an individual approach and the development of personalized methods of prevention and treatment of cholelithiasis in children.


2019 ◽  
Vol 70 (1) ◽  
pp. e523
Author(s):  
Francesco Azzaroli ◽  
Patrizia Simoni ◽  
Rosario Arena ◽  
Elton Dajti ◽  
Federico Ravaioli ◽  
...  

2017 ◽  
Vol 19 (1) ◽  
pp. 68-78
Author(s):  
Rahmad Nugroho ◽  
Waryana Waryana ◽  
Irianton Aritonang

Background: The problem of low exclusive breast feeding achievement in Indonesia is caused by social cultural factors, i.e. the minimal understanding of expecting mother, family, society, and health servant with the exclusive breast feeding. The husband’s and grandmother’s motivation will influence on successful breast feeding. Objective: This study is aimed to reveal the exclusive breast feeding achievement ang the role of grandmother. Method: This is an observational study. The researcher observes the society phenomena in Bangunjiwo Village, Bantul Regency. The subjects of the study are: 1) grandmothers aging ≥ 55 yeras old, 2) breast feeding mothers, and 3) Posyandu cadres. The data are collected by the focus group discussion, detail interview, and documentation.The instruments of the study are FGD, stationaries, tape recorder, and camera. The data are analyzed from the preparation of transcript, data reduction, data presentation, and conclusion. Results: the success of breast feeding is motivated by grandmother’s role, i.e. 1) suggesting, 2) motivating, 3) caring, 4) reminding when mother goes out, 5) giving the stored mother’s milk for working mother, and midwive’s explanation and training for expecting mother. Conclusion: The role of grandmother in exclusive breast feeding will increase: 1) mother’s understanding of breast feeding advantages, 2) mother’s awareness of exclusive breast feeding, and 3) mother’s attitude of exclusive breast feeding. Therefore, a breast feeding mother will be able to increase in practicing exclusive breast feeding by: 1) overcoming obstacles, 2) consuming balanced nutrition, 3) maintaning health and drinking herb. Finally, these will influence the succssful exclusive breast feeding.   Keywords: exclusive breastfeeding, The role of grandmother, mother’s attitude


Children ◽  
2021 ◽  
Vol 8 (7) ◽  
pp. 554
Author(s):  
Stefania Croce ◽  
Maria Antonietta Avanzini ◽  
Corrado Regalbuto ◽  
Erika Cordaro ◽  
Federica Vinci ◽  
...  

In the last few decades, obesity has increased dramatically in pediatric patients. Obesity is a chronic disease correlated with systemic inflammation, characterized by the presence of CD4 and CD8 T cell infiltration and modified immune response, which contributes to the development of obesity related diseases and metabolic disorders, including impaired glucose metabolism. In particular, Treg and Th17 cells are dynamically balanced under healthy conditions, but imbalance occurs in inflammatory and pathological states, such as obesity. Some studies demonstrated that peripheral Treg and Th17 cells exhibit increased imbalance with worsening of glucose metabolic dysfunction, already in children with obesity. In this review, we considered the role of adipose tissue immunomodulation and the potential role played by Treg/T17 imbalance on the impaired glucose metabolism in pediatric obesity. In the patient care, immune monitoring could play an important role to define preventive strategies of pediatric metabolic disease treatments.


Author(s):  
Nehal El Koofy ◽  
Noha Yassin ◽  
Sawsan Okasha ◽  
Hany William ◽  
Wafaa Elakel ◽  
...  

2021 ◽  
Vol 13 (1) ◽  
pp. 98-103
Author(s):  
Agnieszka Pawłowska-Kamieniak ◽  
Paulina Krawiec ◽  
Elżbieta Pac-Kożuchowska

Acute pancreatitis (AP) appears to be rare disease in childhood. In children, it has a different aetiology and course, and requires different management than in adult patients. The diagnosis of AP is based on at least two of the three criteria, which include typical clinical symptoms, abnormalities in laboratory tests and/or imaging studies of the pancreas. There are many known causes leading to AP in children including infections, blunt abdominal trauma, genetic factors, gallstone disease, metabolic disorders, anatomical defects of the pancreas, systemic diseases, as well as drugs, including antiepileptic drugs, and especially preparations of valproic acid. In our study, we present four cases of young patients diagnosed with acute pancreatitis as a complication of valproic acid therapy and we present a review of the literature. We believe that the activity of pancreatic enzymes should be monitored in children treated with valproate preparations in the case of clinical symptoms suggesting AP.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shilpa Tyagi ◽  
Gerald Choon-Huat Koh ◽  
Nan Luo ◽  
Kelvin Bryan Tan ◽  
Helen Hoenig ◽  
...  

Abstract Background Outpatient medical follow-up post-stroke is not only crucial for secondary prevention but is also associated with a reduced risk of rehospitalization. However, being voluntary and non-urgent, it is potentially determined by both healthcare needs and the socio-demographic context of stroke survivor-caregiver dyads. Therefore, we aimed to examine the role of caregiver factors in outpatient medical follow-up (primary care (PC) and specialist outpatient care (SOC)) post-stroke. Method Stroke survivors and caregivers from the Singapore Stroke Study, a prospective, yearlong, observational study, contributed to the study sample. Participants were interviewed 3-monthly for data collection. Counts of PC and SOC visits were extracted from the National Claims Database. Poisson modelling was used to explore the association of caregiver (and patient) factors with PC/SOC visits over 0–3 months (early) and 4–12 months (late) post-stroke. Results For the current analysis, 256 stroke survivors and caregivers were included. While caregiver-reported memory problems of a stroke survivor (IRR: 0.954; 95% CI: 0.919, 0.990) and caregiver burden (IRR: 0.976; 95% CI: 0.959, 0.993) were significantly associated with lower early post-stroke PC visits, co-residing caregiver (IRR: 1.576; 95% CI: 1.040, 2.389) and negative care management strategies (IRR: 1.033; 95% CI: 1.005, 1.061) were significantly associated with higher late post-stroke SOC visits. Conclusion We demonstrated that the association of caregiver factors with outpatient medical follow-up varied by the type of service (i.e., PC versus SOC) and temporally. Our results support family-centred care provision by family physicians viewing caregivers not only as facilitators of care in the community but also as active members of the care team and as clients requiring care and regular assessments.


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