Drug-induced agranulocytosis (clinical observation)
Keyword(s):
The majority of agranulocytosis cases are caused by drugs, including nonsteroidal anti-inflammatory drugs, antibiotics, antithyroid agents, etc. Here, we report a case of severe agranulocytosis in a 67-year-old woman following nonsteroidal anti-inflammatory therapy which was successfully managed using recombinant human granulocyte colony-stimulating factor. Although metamizole, has been in use since 1922 in the management of postoperative pain, colic pain, cancer pain and migraine, agranulocytosis as a direct side effect of metamizole therapy has been rarely reported. It is important to keep in mind this rare but potentially life-threatening adverse effect of metamizole, when initiating therapy.
2015 ◽
Vol 35
(3)
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pp. 244-250
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2014 ◽
Vol 9
(3)
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pp. 761-765
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1998 ◽
Vol 45
(1)
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pp. 191
1998 ◽
Vol 5
(3)
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pp. 221-225
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