3D high-resolution anorectal manometry − selected case reports

2020 ◽  
Vol 99 (6) ◽  
pp. 282-288
Keyword(s):  
High Resolution ◽  
Anorectal Manometry ◽  
Case Reports ◽  
Treatment Plan ◽  
Diagnostic Technique ◽  
Individualized Treatment ◽  
Pathophysiological Mechanisms ◽  
Anorectal Disorders ◽  
Comprehensive Examination ◽  
The Individual

Presented selected case reports are focused on the individual cases of patients suffering from functional anorectal disorders. During the examination algorithm, the emphasis is on 3D high-resolution anorectal manometry, which is a useful diagnostic technique and helps to understand the pathophysiological mechanisms in the field of functional anorectal disorders. Thanks to a comprehensive examination an individualized treatment plan can be determined for each patient.

High Definition Anorectal Manometry Versus High Resolution Anorectal Manometry for Anorectal Disorders

2017 ◽  
Vol 152 (5) ◽  
pp. S316 ◽  
Author(s):  
Dipesh H. Vasant ◽  
Xuelian Xiang ◽  
Mercedes Amieva-Balmori ◽  
Rachael Parr ◽  
Amol Sharma ◽  
...  
Keyword(s):  
High Resolution ◽  
Anorectal Manometry ◽  
High Definition ◽  
Anorectal Disorders

Algorithms for automated montage synthesis of images from laser-scanning confocal microscopes

1995 ◽  
Vol 53 ◽  
pp. 650-651
Author(s):  
D. E. Becker
Keyword(s):  
Image Analysis ◽  
High Resolution ◽  
Laser Scanning ◽  
Cell Counting ◽  
Wide Area ◽  
Data Set ◽  
Computational Synthesis ◽  
Automated Cell Counting ◽  
Partial View ◽  
The Individual

An efficient, robust, and widely-applicable technique is presented for computational synthesis of high-resolution, wide-area images of a specimen from a series of overlapping partial views. This technique can also be used to combine the results of various forms of image analysis, such as segmentation, automated cell counting, deblurring, and neuron tracing, to generate representations that are equivalent to processing the large wide-area image, rather than the individual partial views. This can be a first step towards quantitation of the higher-level tissue architecture. The computational approach overcomes mechanical limitations, such as hysterisis and backlash, of microscope stages. It also automates a procedure that is currently done manually. One application is the high-resolution visualization and/or quantitation of large batches of specimens that are much wider than the field of view of the microscope.The automated montage synthesis begins by computing a concise set of landmark points for each partial view. The type of landmarks used can vary greatly depending on the images of interest. In many cases, image analysis performed on each data set can provide useful landmarks. Even when no such “natural” landmarks are available, image processing can often provide useful landmarks.

The “individual” in Johann Friedrich Overbeck’s and Franz Liszt’s Seven Sacraments

2013 ◽  
Vol 54 (4) ◽  
pp. 339-356
Author(s):  
Dolores Pesce
Keyword(s):  
Nineteenth Century ◽  
Franz Liszt ◽  
Individualized Treatment ◽  
Sacred Art ◽  
The Individual ◽  
Individual Voice ◽  
Emotional Effects ◽  
The Church

In the preface to his Septem sacramenta (1878–1884), Franz Liszt acknowledged its stimulus — drawings completed in 1862 by the German painter J. F. Overbeck (1789–1869). This essay explores what Liszt likely meant by his and Overbeck’s “diametrically opposed” approaches and speculates on why the composer nonetheless acknowledged the artist’s work. Each man adopted an individualized treatment of the sacraments, neither in line with the Church’s neo-Thomistic philosophy. Whereas the Church insisted on the sanctifying effects of the sacraments’ graces, Overbeck emphasized the sacraments as a means for moral edification, and Liszt expressed their emotional effects on the receiver. Furthermore, Overbeck embedded within his work an overt polemical message in response to the contested position of the pope in the latter half of the nineteenth century. For many in Catholic circles, he went too far. Both works experienced a problematic reception. Yet, despite their works’ reception, both Overbeck and Liszt believed they had contributed to the sacred art of their time. The very individuality of Overbeck’s treatment seems to have stimulated Liszt. True to his generous nature, Liszt, whose individual voice often went unappreciated, publicly recognized an equally individual voice in the service of the Church.

An individualized treatment rule to optimize probability of remission by continuation, switching, or combining antidepressant medications after failing a first-line antidepressant in a two-stage randomized trial

2021 ◽  
pp. 1-10
Author(s):  
Ronald C. Kessler ◽  
Toshi A. Furukawa ◽  
Tadashi Kato ◽  
Alex Luedtke ◽  
Maria Petukhova ◽  
...  
Keyword(s):  
Pragmatic Trial ◽  
Secondary Analysis ◽  
Individualized Treatment ◽  
Second Line ◽  
Open Label ◽  
Individual Level ◽  
Ensemble Machine Learning ◽  
Medication Selection ◽  
The Individual ◽  
Optimized Treatment

Abstract Background There is growing interest in using composite individualized treatment rules (ITRs) to guide depression treatment selection, but best approaches for doing this are not widely known. We develop an ITR for depression remission based on secondary analysis of a recently published trial for second-line antidepression medication selection using a cutting-edge ensemble machine learning method. Methods Data come from the SUN(^_^)D trial, an open-label, assessor blinded pragmatic trial of previously-untreated patients with major depressive disorder from 48 clinics in Japan. Initial clinic-level randomization assigned patients to 50 or 100 mg/day sertraline. We focus on the 1549 patients who failed to remit within 3 weeks and were then rerandomized at the individual-level to continuation with sertraline, switching to mirtazapine, or combining mirtazapine with sertraline. The outcome was remission 9 weeks post-baseline. Predictors included socio-demographics, clinical characteristics, baseline symptoms, changes in symptoms between baseline and week 3, and week 3 side effects. Results Optimized treatment was associated with significantly increased cross-validated week 9 remission rates in both samples [5.3% (2.4%), p = 0.016 50 mg/day sample; 5.1% (2.7%), p = 0.031 100 mg/day sample] compared to randomization (30.1–30.8%). Optimization was also associated with significantly increased remission in both samples compared to continuation [24.7% in both: 11.2% (3.8%), p = 0.002 50 mg/day sample; 11.7% (3.9%), p = 0.001 100 mg/day sample]. Non-significant gains were found for optimization compared to switching or combining. Conclusions An ITR can be developed to improve second-line antidepressant selection, but replication in a larger study with more comprehensive baseline predictors might produce stronger and more stable results.

Traditional measures of normal anal sphincter function using high-resolution anorectal manometry (HRAM) in 115 healthy volunteers

2014 ◽  
Vol 26 (5) ◽  
pp. 625-635 ◽  
Author(s):  
E. V. Carrington ◽  
A. Brokjaer ◽  
H. Craven ◽  
N. Zarate ◽  
E. J. Horrocks ◽  
...  
Keyword(s):  
High Resolution ◽  
Healthy Volunteers ◽  
Anal Sphincter ◽  
Anorectal Manometry ◽  
Sphincter Function ◽  
Anal Sphincter Function

High-Resolution Facial Feature Saliency Mapping

Perception ◽  
1986 ◽  
Vol 15 (4) ◽  
pp. 373-386 ◽  
Author(s):  
Nigel D Haig
Keyword(s):  
Image Processing ◽  
High Resolution ◽  
Facial Feature ◽  
Human Beings ◽  
Comparison Process ◽  
Compression Technique ◽  
Feature Saliency ◽  
Basic Set ◽  
Computational Speed ◽  
The Individual

For recognition of a target there must be some form of comparison process between the image of that target and a stored representation of that target. In the case of faces there must be a very large number of such stored representations, yet human beings seem able to perform comparisons at phenomenal speed. It is possible that faces are memorised by fitting unusual features or combinations of features onto a bland prototypical face, and such a data-compression technique would help to explain our computational speed. If humans do indeed function in this fashion, it is necessary to ask just what are the features that distinguish one face from another, and also, what are the features that form the basic set of the prototypical face. The distributed apertures technique was further developed in an attempt to answer both questions. Four target faces, stored in an image-processing computer, were each divided up into 162 contiguous squares that could be displayed in their correct positions in any combination of 24 or fewer squares. Each observer was required to judge which of the four target faces was displayed during a 1 s presentation, and the proportion of correct responses for each individual square was computed. The resultant response distributions, displayed as brightness maps, give a vivid impression of the relative saliency of each feature square, both for the individual targets and for all of them combined. The results, while broadly confirming previous work, contain some very interesting and surprising details about the differences between the target faces.

High-resolution anorectal manometry in newborns: normative values and diagnostic utility in Hirschsprung disease

2014 ◽  
Vol 26 (11) ◽  
pp. 1565-1572 ◽  
Author(s):  
Y.-F. Tang ◽  
J.-G. Chen ◽  
H.-J. An ◽  
P. Jin ◽  
L. Yang ◽  
...  
Keyword(s):  
High Resolution ◽  
Anorectal Manometry ◽  
Hirschsprung Disease ◽  
Normative Values ◽  
Diagnostic Utility
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