Photorefractive keratectomy – the first generation of laser vision correction

Photorefractive keratectomy (PRK) is the first generation of laser vision correction, which marked the beginning of the era of laser keratorefractive surgery. The technology can improve vision in case of myopia, hypermetropia, and astigmatism. The article analyzes the advantages and disadvantages of the PRK method, its risks and side effects. The data obtained as a result of the analysis of scientific publications and by practical means are presented.

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LASIK – the second generation of laser vision correction

The Eye ◽

10.33791/2222-4408-2020-3-35-40 ◽

2020 ◽

Vol 22 (3(131)) ◽

pp. 35-40

Author(s):

T. Yu. Shilova

Keyword(s):

Side Effects ◽

Second Generation ◽

Photorefractive Keratectomy ◽

Wide Spread ◽

Scientific Publications ◽

Advantages And Disadvantages ◽

Vision Correction ◽

Laser Vision ◽

Keratorefractive Surgery

LASIK (Laser-Assisted in Situ Keratomileusis) is the second generation of laser vision correction methods, which replaced PRK (photorefractive keratectomy) and became a wide-spread method of laser keratorefractive surgery. The technology can improve vision in cases of myopia, hypermetropia, and astigmatism. The article analyzes the advantages and disadvantages of the LASIK method, its risks and side effects. Presented data is obtained from the analysis of scientific publications and by practical means.

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ReLEx® SMILE® – the third generation of laser eye surgery

The Eye ◽

10.33791/2222-4408-2020-4-52-58 ◽

2020 ◽

Vol 22 (4(132)) ◽

pp. 52-58

Author(s):

T. Yu. Shilova

Keyword(s):

Side Effects ◽

First Generation ◽

Second Generation ◽

Third Generation ◽

Scientific Publications ◽

Eye Surgery ◽

Advantages And Disadvantages ◽

The Third ◽

Small Incision ◽

Lenticule Extraction

ReLEx® (Refractive lenticule extraction) SMILE® (SMall Incision Lenticula Extraction) is the third generation of laser eye surgery, which is a follow-on to PRK (the first generation) and LASIK (the second generation). This technology has expanded the possibilities for the comfort and safety of the procedure, reduced the requirements for the thickness of the cornea, and made it extremely comfortable for the patient. SMILE® method helps improve vision in case of myopia, myopic and mixed astigmatism. The article analyzes the advantages and disadvantages of this technology, its possible risks and side effects. The data represented in this article was obtained by analyzing scientific publications and practical expertise.

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Laser vision correction technologies: from simple to complex

The Eye ◽

10.33791/2222-4408-2020-1-48-50 ◽

2020 ◽

Vol 22 (129) ◽

pp. 48-50

Author(s):

Tatiana Shilova

Keyword(s):

Side Effects ◽

Refractive Surgery ◽

Contact Lenses ◽

Common Method ◽

Corneal Curvature ◽

Power Laser ◽

Scientific Publications ◽

Vision Correction ◽

Laser Vision ◽

Laser Refractive Surgery

Laser vision correction is a simple and safe way to improve vision in cases of myopia, hyperopia and astigmatism. We analyzed differences of the existing laser vision correction technologies, their risks and side effects. The main objective of laser vision correction is to change corneal curvature in order to change its refractive power. Laser refractive surgery is the most common method of eliminating the need for glasses or contact lenses. The presented data was obtained from the analysis of scientific publications and by practical means.

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Faculty Opinions recommendation of Long-term follow-up after laser vision correction in physicians: quality of life and patient satisfaction.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718293989.793492928 ◽

2014 ◽

Author(s):

Karl Stonecipher

Keyword(s):

Quality Of Life ◽

Patient Satisfaction ◽

Vision Correction ◽

Long Term Follow Up ◽

Laser Vision

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A Review of Drug Side Effect Identification Methods

Current Pharmaceutical Design ◽

10.2174/1381612826666200612163819 ◽

2020 ◽

Vol 26 (26) ◽

pp. 3096-3104 ◽

Cited By ~ 1

Author(s):

Shuai Deng ◽

Yige Sun ◽

Tianyi Zhao ◽

Yang Hu ◽

Tianyi Zang

Keyword(s):

Side Effects ◽

Future Research ◽

Drug Side Effects ◽

Important Indicator ◽

Advantages And Disadvantages ◽

Key Points ◽

Network Methods ◽

Future Research Directions ◽

The One ◽

Approved Drugs

Drug side effects have become an important indicator for evaluating the safety of drugs. There are two main factors in the frequent occurrence of drug safety problems; on the one hand, the clinical understanding of drug side effects is insufficient, leading to frequent adverse drug reactions, while on the other hand, due to the long-term period and complexity of clinical trials, side effects of approved drugs on the market cannot be reported in a timely manner. Therefore, many researchers have focused on developing methods to identify drug side effects. In this review, we summarize the methods of identifying drug side effects and common databases in this field. We classified methods of identifying side effects into four categories: biological experimental, machine learning, text mining and network methods. We point out the key points of each kind of method. In addition, we also explain the advantages and disadvantages of each method. Finally, we propose future research directions.

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Transepithelial Photorefractive Keratektomy after a Clear Lens Exchange

Vision ◽

10.3390/vision5010008 ◽

2021 ◽

Vol 5 (1) ◽

pp. 8

Author(s):

Diego de Ortueta

Keyword(s):

Refractive Lens Exchange ◽

Visual Outcomes ◽

Vision Correction ◽

Refractive Lens ◽

Laser Vision ◽

Lens Surgery ◽

Optical Zone ◽

The Mean ◽

Pulse Technology

Purpose: We evaluated the refractive visual outcomes and efficacy of Transepithelial Photorefractive Keratectomy (TransPRK) using Smart Pulse Technology with static and dynamic cyclotorsion and the AMARIS 1050 Hz RS laser platform from Schwind in the eyes after a refractive lens exchange. Setting/Venue: Aurelios Augenlaserzentrum, Recklinghausen. Methods: We retrospectively evaluated the data of 552 consecutive eyes treated with refractive lens exchange between 2016 and 2019. A total of 47 eyes (8.5%) required a touch up after the clear lens exchange. From 43 eyes of 43 patients, we obtained a minimum follow up of 3 months. In all cases, we performed a TransPRK with a minimum optical zone of 7.2 mm, centering the ablation on the vertex of the cornea. Results: The average age of the treated eyes was 57 years old, with a range between 48 and 68 years. The mean treated sphere was 0.42 diopters (D), with a range between −1.0 and +1.75 D. The mean astigmatism was 1.06 D. Postoperatively, after laser vision correction, we reduced the sphere to a mean of 0.11 D (range −0.5 to +0.75 D), and, postoperatively, the mean astigmatism was 0.25 D (range −0.75 to 0 D). The predictability for a spheric equivalent (SEQ) of 0.5 D was 91%, and for 1 D it was 100% of the cases. No eye lost more than one Snellen line. Conclusions: TransPRK with smart pulse was predictable for correcting ametropia after Clear Lens Surgery.

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Adjuvant Radiotherapy after Surgical Excision in Keloids

Medicina ◽

10.3390/medicina57070730 ◽

2021 ◽

Vol 57 (7) ◽

pp. 730

Author(s):

Jeong Won Lee ◽

Ki Ho Seol

Keyword(s):

Quality Of Life ◽

Side Effects ◽

Adjuvant Therapy ◽

Local Control ◽

Adjuvant Radiotherapy ◽

Surgical Excision ◽

Recurrence Rates ◽

High Tendency ◽

Advantages And Disadvantages

Keloids are a benign fibroproliferative disease with a high tendency of recurrence. Keloids cause functional impairment, disfigurement, pruritus, and low quality of life. Many therapeutic options have been used for keloids. However, the high recurrence rates have led to the use of adjuvant therapy after surgical keloid excision. There are different radiotherapy regimens available, and the advantages and disadvantages of each are still unclear. The aim of this review is to explain the appropriate radiotherapy regimen for keloids as well as discuss the recent reports on keloid management with radiotherapy. Adjuvant radiotherapy after surgical excision for keloids yields excellent local control with tolerable side effects. Hypofractionated radiotherapy with a BED of more than 28 Gy (α/β value of 10) after excision is recommended in the light of its biologic background.

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Incidence of Intraoperative and Early Postoperative Adverse Events in a Large Cohort of Consecutive Laser Vision Correction Treatments

American Journal of Ophthalmology ◽

10.1016/j.ajo.2019.10.011 ◽

2020 ◽

Vol 210 ◽

pp. 97-106 ◽

Cited By ~ 1

Author(s):

Julie M. Schallhorn ◽

Steven C. Schallhorn ◽

David Teenan ◽

Stephen J. Hannan ◽

Martina Pelouskova ◽

...

Keyword(s):

Adverse Events ◽

Large Cohort ◽

Vision Correction ◽

Laser Vision

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Assessment of changes in the biomechanical properties of the cornea after FemtoLASIK surgery

Modern technologies in ophtalmology ◽

10.25276/2312-4911-2021-5-121-125 ◽

2021 ◽

pp. 121-125

Author(s):

E.V. Boiko ◽

◽

E.S. Togo ◽

I.B. Litvin ◽

A.B. Kachanov ◽

...

Keyword(s):

Key Words ◽

Refractive Surgery ◽

Biomechanical Properties ◽

Corvis St ◽

Vision Correction ◽

Before And After ◽

Keratorefractive Surgery

Purpose. The aim of the study is to investigate the biomechanical properties of the cornea before and after FemtoLASIK in patients with myopia. Material and methods. 24 patients (42 eyes) underwent refractive vision correction using the FemtoLASIK method. The Oculus CORVIS ST ® device (Oculus, Germany) was used to assess the biomechanical properties of the cornea. Results. A statistically significant decrease in the rigidity and strength of the cornea was noted after keratorefractive surgery. Conclusion. Refractive surgery using FemtoLASIK technology leads to a decrease in the rigidity of the cornea, and therefore to a reduction in its framework properties. Key words: refractive surgery, FemtoLASIK, myopia, laser correction, biomechanical properties of the cornea, Oculus CORVIS ST ®.

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