Clinical Outcomes of Aberration-Free All Surface Laser Ablation (ASLA) vs. Aberration-Free ASLA Assisted by Smart Pulse Technology in High Myopia: A One-Year Follow-Up Study

Purpose. To compare the clinical outcomes of aberration-free all surface laser ablation (ASLA) with and without the use of smart pulse technology (SPT) in high myopia. Methods. This study retrospectively analyzed 138 eyes (138 patients, only the right eye was selected) treated for high myopia (spherical equivalent ≥−6.00 diopters) using aberration-free ASLA (non-SPT group; 85 eyes) and aberration-free ASLA assisted by SPT (SPT group; 53 eyes). Examinations such as visual acuity, refraction, and haze were performed before the 12-month follow-up. Corneal epithelial healing time was assessed in the first postoperative day. Visual acuity and refraction examination were performed at 7 days and 1, 3, 6, and 12 months postoperatively. Corneal haze was evaluated in 1, 3, 6, and 12 months. Safety, efficacy, and corneal wavefront aberrations were assessed 12 months after the treatment. Results. At 12 months postoperatively, 60% versus 40% of eyes achieved 20/16 Snellen lines or better, and 92% versus 82% of eyes achieved 20/20 Snellen lines or better visual acuity in the SPT and the non-SPT groups, respectively. The average postoperative epithelial healing time was 3.75 ± 1.00 days in the SPT group and 3.73 ± 1.30 days in the non-SPT group ( P ≥ 0.05 ). The safety and the efficacy index of the SPT group were better than those of the non-SPT group in the follow-ups. The attempted spherical equivalent before the surgery and the achieved spherical equivalent at 12 months were comparable between the two groups. Regarding the aberrations, the results of Coma 90° in the SPT group were better than those in the non-SPT group ( P ≤ 0.05 ), but the increase of RMS HOAs (root mean square higher order aberrations), Coma 0°, and spherical aberration postoperatively had no statistical difference between the two groups ( P ≥ 0.05 ). Conclusions: Both aberration-free ASLA with and without SPT showed favorable safety, effectiveness, and predictability within 12 months for high myopia. And, ASLA using SPT might have potential advantages in the long-term visual quality.

SmartSurfACE transepithelial photorefractive keratectomy with mitomycin C enhancement after small incision lenticule extraction

Background To evaluate predictability, stability, efficacy, and safety of transepithelial photorefractive keratectomy (TPRK) using smart pulse technology (SPT) (SmartSurface procedure) of Schwind Amaris with mitomycin C for correction of post small incision lenticule extraction (SMILE) myopic residual refractive errors. Method This study is a prospective, non-comparative case series conducted at a private eye centre in Ismailia, Egypt, on eyes with post-SMILE myopic residual refractive errors because of undercorrection or suction loss (suction loss occurred after the posterior lenticular cut and the creation of side-cuts; redocking was attempted, and the treatment was completed in the same session with the same parameters) with myopia or myopic astigmatism. The patients were followed up post-SMILE for six months before the SmartSurface procedure, and then they were followed up for one year after that. TPRK were performed using Amaris excimer laser at 500 kHz. The main outcomes included refractive predictability, stability, efficacy, safety and any reported complications. Results This study included 68 eyes of 40 patients out of 1920 total eyes (3.5%) with post-SMILE technique myopic residual refractive errors. The average duration between the SMILE surgery and TPRK was 6.7 ± 0.4 months (range 6 to 8 months). The mean refractive spherical equivalent (SE) was within ± 0.50 D of plano correction in 100% of the eyes at 12 months post-TPRK. Astigmatism of < 0.50 D was achieved in 100% of the eyes. The mean of the residual SE error showed statistically significant improvement from preoperative − 1.42 ± 0.52 D to 0.23 ± 0.10 D (P < 0.0001). Uncorrected distance visual acuity (UDVA) (measured by Snellen's chart and averaged in logMAR units) was improved significantly to 0.1 ± 0.07 (P < 0.0001). UDVA was 0.2 logMAR or better in 100% of the eyes, 0.1 logMAR or better in 91.2% of the eyes, and 0.0 logMAR in 20.6% of the eyes. Corrected distance visual acuity (CDVA) remained unchanged in 79.4% of eyes. 14.7% of eyes gained one line of CDVA (Snellen). 5.9% of eyes gained two lines of CDVA (Snellen). Conclusion Transepithelial photorefractive keratectomy using smart pulse technology with mitomycin C enhancement after SMILE is a safe, predictable, stable, and effective technique.

Management of high cows-share-contribution of SCC to the bulk milk tank by acoustic pulse technology (APT)

A cow with mastitis has a high somatic cell count (SCC) in its milk. Cow-share-contribution of somatic cells to the bulk milk tank (BMTSCC) refers to the relative addition made by each cow’s milk to the bulk tank’s SCC. Since bulk milk is graded and priced according to the BMTSCC, high-yielding cows with mastitis are the main contributors to penalizations in milk price. The benefits of acoustic pulse technology (APT) application to tissues are well documented, including its anti-inflammatory effect and restoration of tissue function by triggering natural healing processes. An APT-based device was developed specifically for treating mastitis in dairy cows. It enables rapid and deep penetration of the acoustic pulses over a large area of the udder in a single session. A study was performed on six farms with a total of 3,900 cows. One unit of cow-share-contribution equaled the addition of 1,000 cells to each mL of the bulk milk volume above the mean BMTSCC. A total of 206 cows were selected: 103 were treated with APT and 103 served as controls. All of the cows contributed over 1.5 units to the BMTSCC at the time of treatment. Seventy-five days after APT treatment, 2 of the 103 treated cows (1.9%) were culled, compared to 19 (18.5%) of the 103 control cows, as well as infected quarter dry-off in 5 others (4.85%). Overall success was defined as a decrease of >75% in cow-share-contribution from treatment time in two of the three monthly milk recordings following treatment. Results indicated 57.3% success for the APT-treated cows vs. 14.6% for the untreated control groups. Highest share-contribution provide an additional tool for the farmer’s decision of how to control BMTSCC. Because the cow-share-contribution value is relative to herd size and BMTSCC, this study included a similar number of cows, with similar SCC and milk yield from each of the six herds.

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

The effect of acoustic pulse technology (APT) on recovery, culling, milk yield, and economic benefits for 118 cows with subclinical mastitis was compared with a no-treatment control (59 vs. 59), and another 118 APT-treated cows with clinical mastitis were compared with antibiotic-treated controls (59 vs. 59). Recovery was defined as a decrease in somatic cell count (SCC) to <250 × 103 cells/mL in at least two out of three monthly milk recordings after treatments. For the subclinically infected cows, APT treatment resulted in 65.5% recovery, 0% culling, and additional milk yield of 2.74 L/cow per day compared to 35.6% recovery and 5.1% culling in the no-treatment controls. For the clinically infected cows, APT treatment resulted in 67.8% recovery, 6.8% culling, and additional milk yield of 3.9 L/cow per day compared to 35.6% recovery and 32.2% culling in the antibiotic-treated group. Bacteriological analysis was run for 95 (80%) cows with clinical mastitis (APT-46; AB-49). For cows with Escherichia coli infection, 85.7% (18/21) treated with APT recovered vs. 17.6% (3/17) in the antibiotic-treated group; for cows with streptococcal infection, 66.0% (12/18) in the APT-treated group recovered vs. 44.4% (8/18) in the antibiotic-treated group.

Transepithelial Photorefractive Keratektomy after a Clear Lens Exchange

Purpose: We evaluated the refractive visual outcomes and efficacy of Transepithelial Photorefractive Keratectomy (TransPRK) using Smart Pulse Technology with static and dynamic cyclotorsion and the AMARIS 1050 Hz RS laser platform from Schwind in the eyes after a refractive lens exchange. Setting/Venue: Aurelios Augenlaserzentrum, Recklinghausen. Methods: We retrospectively evaluated the data of 552 consecutive eyes treated with refractive lens exchange between 2016 and 2019. A total of 47 eyes (8.5%) required a touch up after the clear lens exchange. From 43 eyes of 43 patients, we obtained a minimum follow up of 3 months. In all cases, we performed a TransPRK with a minimum optical zone of 7.2 mm, centering the ablation on the vertex of the cornea. Results: The average age of the treated eyes was 57 years old, with a range between 48 and 68 years. The mean treated sphere was 0.42 diopters (D), with a range between −1.0 and +1.75 D. The mean astigmatism was 1.06 D. Postoperatively, after laser vision correction, we reduced the sphere to a mean of 0.11 D (range −0.5 to +0.75 D), and, postoperatively, the mean astigmatism was 0.25 D (range −0.75 to 0 D). The predictability for a spheric equivalent (SEQ) of 0.5 D was 91%, and for 1 D it was 100% of the cases. No eye lost more than one Snellen line. Conclusions: TransPRK with smart pulse was predictable for correcting ametropia after Clear Lens Surgery.

INCREASE OF EFFICIENCY OF WASTE-HEAT BOILERS WITHIN SELECTION OF COMPRESSOR SHOP LAYOUT

Increasing the efficiency of steam boilers is largely due to the timely cleaning of heating surfaces, which improves their steam efficiency and saves a significant amount of conditional fuel. One of the promising directions in this way is the use of pneumatic pulse technology, which ensures the production of highefficiency, safe, remotely controlled cleaning systems. The implementation of this technology involves, among other things, evaluating the composition and layout of the necessary equipment of the compressor shop, solving the problems of their optimal design.

CUSTOMIZED WEBGIS SOLUTIONS FOR EXPOSOMICS

Exposomics is a science aiming at quantifying the effects on human health of all the factors influencing it, but genetic ones. They include environment, food, mobility habits and cultural factors. The percentage of the world’s population living in the urban areas is projected to increase in the next decades. Rising industrialization, urbanization and heterogeneity are leading to new challenges for public health and quality of life in the population. The prevalence of conditions such as asthma and cardiovascular diseases is increasing due to a change in lifestyle and air quality. This enlightens the necessity of targeted interventions to increase citizens’ quality of life and decrease their health risks. Within the EU H2020 PULSE project, a multi-technological system to assist the population in the prevention and treatment of asthma and type 2 diabetes has been developed. The system created in PULSE features several parts, such as a personal App for the citizens, a set of air quality sensors, a WebGIS and dashboards for the public health operators. Citizens are directly involved in an exchange paradigm in which they send their own data and receive feedbacks and suggestions about their health in return. The WebGIS is a very distinguishing element of the PULSE technology and the paper illustrates its main functionalities focusing on the distinguishing and innovative features developed.