Seroprevalence of Newcastle disease and other infectious diseases in backyard chickens at markets in Eastern Shewa zone, Ethiopia

Newcastle disease affects birds of different breeds and ages (turkeys, quails, guinea fowls, chickens). Given the possibility of spreading the disease by birds of other species, including migratory birds, it makes more sense to immunize chickens during their long-distance migration. The main measure of disease prevention remains its competent specific prevention with the use of live and inactivated vaccines, as the specialists of the Khankai branch of the Khorol Veterinary Station for animal diseases control told the public. The only way to protect against the disease is to vaccinate all types of poultry.

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Seroprevalence of Newcastle Disease Virus in Backyard Chickens at Gazipur District of Bangladesh

International Journal of Natural Sciences ◽

10.3329/ijns.v3i1.28583 ◽

2016 ◽

pp. 22-25 ◽

Cited By ~ 1

Author(s):

MB Hossain ◽

MZ Islam ◽

MS Bari ◽

MA Torab ◽

MAH Mondal

Keyword(s):

Newcastle Disease Virus ◽

Disease Virus ◽

Newcastle Disease ◽

Haemagglutination Inhibition ◽

Cross Sectional Study ◽

Strain Identification ◽

Cross Sectional ◽

Study Population ◽

Backyard Chickens ◽

Individual Serum Sample

A cross-sectional study was conducted to estimate the seroprevalence of Newcastle disease (ND) in backyard chickens at Gazipur district of Bangladesh. Individual serum sample was collected from clinically healthy and non-immunized backyard chickens in four randomly selected upazilla (Sreepur, Kapasia, Kaliakor and Gazipur sadar) under Gazipur district. A total of two hundred samples (50 from each upazila) were collected from October 2009 to February 2010. Haemagglutination Inhibition (HI) test was used to determine titer of antibodies against Newcastle disease virus. The mean log2 HI titer to NDV in blood sera of the study population were found 5.54, 6.25, 4.38, 5.32 and seroprevalence were 42.53%, 45.99%, 31.91%, and37.82% in Sreepur, Kapasia, Kaliakor and Gazipur sadar upazilas respectively. The overall antibody titer and seroprevalence of Newcastle disease virus was recorded 5.37 and 39.56% respectively. Further detailed study focusing on Newcastle Disease (ND) virus strain identification and improved management packages to reduce the prevalence of Newcastle Disease (ND) are recommended.International Journal of Natural Sciences (2013), 3(1-4) 22-25

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Exploring the Prospects of Engineered Newcastle Disease Virus in Modern Vaccinology

Viruses ◽

10.3390/v12040451 ◽

2020 ◽

Vol 12 (4) ◽

pp. 451 ◽

Cited By ~ 1

Author(s):

Muhammad Bashir Bello ◽

Khatijah Yusoff ◽

Aini Ideris ◽

Mohd Hair-Bejo ◽

Abdurrahman Hassan Jibril ◽

...

Keyword(s):

Molecular Biology ◽

Infectious Diseases ◽

Newcastle Disease Virus ◽

Disease Virus ◽

Newcastle Disease ◽

Reverse Genetics ◽

Emerging Infectious Diseases ◽

Genetically Engineered ◽

Antigen Delivery ◽

Design Development

Many traditional vaccines have proven to be incapable of controlling newly emerging infectious diseases. They have also achieved limited success in the fight against a variety of human cancers. Thus, innovative vaccine strategies are highly needed to overcome the global burden of these diseases. Advances in molecular biology and reverse genetics have completely restructured the concept of vaccinology, leading to the emergence of state-of-the-art technologies for vaccine design, development and delivery. Among these modern vaccine technologies are the recombinant viral vectored vaccines, which are known for their incredible specificity in antigen delivery as well as the induction of robust immune responses in the vaccinated hosts. Although a number of viruses have been used as vaccine vectors, genetically engineered Newcastle disease virus (NDV) possesses some useful attributes that make it a preferable candidate for vectoring vaccine antigens. Here, we review the molecular biology of NDV and discuss the reverse genetics approaches used to engineer the virus into an efficient vaccine vector. We then discuss the prospects of the engineered virus as an efficient vehicle of vaccines against cancer and several infectious diseases of man and animals.

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Prevalence of common diseases of broiler and layer at Gazipur district in Bangladesh

Asian Journal of Medical and Biological Research ◽

10.3329/ajmbr.v3i2.33582 ◽

2017 ◽

Vol 3 (2) ◽

pp. 290-293 ◽

Cited By ~ 2

Author(s):

Md Arifur Rahman ◽

Md Mostafijur Rahman ◽

Monalisha Moonmoon ◽

Khondoker Jahengir Alam ◽

Md Zahirul Islam

Keyword(s):

Infectious Diseases ◽

Mixed Infection ◽

Newcastle Disease ◽

Present Status ◽

Infectious Bursal Disease ◽

Fowl Cholera ◽

Common Diseases ◽

Bursal Disease ◽

Veterinary Hospital ◽

Commercial Chickens

The present study was conducted to determine the prevalence of broiler and layer diseases at Gazipur sadar upazilla veterinary hospital in Bangladesh. A total of 296 either dead or sick birds were considered for the present study. Diagnosis of different diseases was made on the basis of history, owners complains, age of birds, presenting signs, clinical and necropsy examination findings. The prevalence of diseases was recorded in broiler (n=189) 63.9% and layer (n=107) 36.1%. In broiler the prevalence of Colibacillosis (33.4%) was higher followed by Omphalitis (23.8%), Infectious Bursal Disease-IBD (15.3%), Newcastle disease-ND (9.0%), mixed infection (7.4%), Gout (5.3%) and Coccidiosis (5.8%). In case of layer highest prevalence was recorded in Salmonellosis (19.6%). while other diseases were Collibacilosis (15.9%), Mycoplasmosis (12.1%), ND (10.3%), IBD (8.4), Mareks (9.3%), mixed infection (8.4%), Fowl Cholera (4.7%) and Mycotoxicosis (4.7%). The present findings will help poultry researchers and practitioner to know the present status of infectious diseases of commercial chickens in the study area and also help to establish flock based control strategy.Asian J. Med. Biol. Res. June 2017, 3(2): 290-293

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Newcastle Disease Virus as a Promising Vector against Infectious Diseases and as a Potential Agent against Cancers

Frontiers in Anti-Infective Drug Discovery ◽

10.2174/9781608059126114030006 ◽

2014 ◽

pp. 173-193

Keyword(s):

Infectious Diseases ◽

Newcastle Disease Virus ◽

Disease Virus ◽

Newcastle Disease

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Seroprevalence and molecular detection of Newcastle disease virus in backyard chickens in Tripoli, Libya

Open Veterinary Journal ◽

10.4314/ovj.v10i1.13 ◽

2020 ◽

Vol 10 (1) ◽

pp. 80-85

Author(s):

Emhemed A. Gedara ◽

Hesham A. Alseed ◽

Abdulwahab M. Kammon ◽

Abdunaser S. Dayhum ◽

Mohamed A. Benothman ◽

...

Keyword(s):

Real Time ◽

Newcastle Disease ◽

Viral Disease ◽

Elisa Test ◽

Reverse Transcription Pcr ◽

Lack Of Information ◽

Total Prevalence ◽

Commercial Poultry ◽

Backyard Chickens ◽

Backyard Chicken

Background: Newcastle disease (ND) is a viral disease that affecting many avian species all over the world.Aim: ND has been successfully controlled by the vaccination of commercial poultry in Libya. However, there was a lack of information about the situation of ND in backyard chickens. Therefore, this study determined the prevalence of ND in backyard chickens in different locations of Tripoli.Methods: A total number of 280 cloacal swabs (190 in summer and 90 in winter) and 412 sera were collected from non-vaccinated backyard chicken flocks in different geographical locations within the area of Tripoli namely Qasr Ben Ghashier, Al-Sawani, Souq Al-Gomaa, Tajourah, Ein Zara, and Janzour. Cloacal swabs and sera were tested by real time polymerase chain reaction (PCR) and ELISA, respectively.Results: The prevalence of ND virus (NDV) infection in backyard chickens in different locations of Tripoli during summer and winter was 45% using real-time reverse transcription-PCR. Except in Qasr Ben Ghashier, the prevalence in summer season was significantly higher than in winter (X2 = 46.13, p ≥ 0.00001). ELISA test revealed 218 positive out of 412 tested samples with total prevalence of 53% across the city of Tripoli in all regions. Obviously, Qasr Ben Ghashier had significantly (X2 = 74.09, p ≥ 0.00001) the highest prevalence (82%) of NDV specific antibodies followedby Tajourah (68%).Conclusion: This study demonstrated the situation of ND in backyard chicken highlighting the necessity of a comprehensive vaccination plan for backyard chickens. Keywords: Backyard chickens, ELISA, Newcastle disease, Prevalence, Real time PCR.

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