scholarly journals Efektivitas Intervensi Motor Imagery (MI) terhadap Rehabilitasi Pasien Post stroke: A Systematic Review

Author(s):  
Bernadetta Germia Aridamayanti ◽  
Gevi Melliya Sari ◽  
Wimar Anugrah Romadhon

Background: Motor Imagery (MI) is an intervention to improve motor skills in post stroke hemiparesis patients by focusing on weak body parts. Objective: To describe the effectiveness of providing MI in the rehabilitation of post stroke patients. Method: The database used to identify suitable articles obtained from Scopus, ProQuest and Pubmed was limited to the last 5 years of publication from 2016 to 2020, English, and fulltext articles. The literature review used the keyword "Motor Imagery" AND "Stroke Rehabilitation". In searching articles used "AND". Only 8 articles met the inclusion criteria. This review was from these 8 articles. Results: MI has effectiveness in cognitive, sensory and motor post-stroke patients by stimulating neuroplasticity in various areas of the brain so that it accelerates the increase in O2, glucose and various metabolites that lead to increased regional metabolism through dilation of cerebral arterioles and capillaries. MI which is given routinely will help the recovery of motor function of post-stroke patients and increase patient independence. Conclusion: MI has a lot of effectiveness in the rehabilitation of post stroke patients. Suggestion: MI is considered necessary to be applied in hospitals in Indonesia. Keywords: motor imagery; stroke; rehabilitation ABSTRAK Latar belakang: Motor Imagery (MI) merupakan intervensi untuk meningkatkan keterampilan motorik pada pasien hemiparesis post stroke dengan berfokus pada bagian tubuh yang lemah. Tujuan: Untuk menjabarkan efektivitas pemberian MI pada rehabilitasi pasien post stroke. Metode: Database yang digunakan dalam penelitian ini adalah Scopus, Proquest dan Pubmed terbatas untuk publikasi 5 tahun terakhir dari 2016 hingga 2020, full text article dan berbahasa Inggris. Kata kunci yang digunakan adalah “Motor Imagery” AND “Stroke Rehabilitation”. Systematic review ini menggunakan 8 artikel yang sesuai dengan kriteria inklusi. Hasil: MI memiliki efektivitas pada kognitif, sensorik dan motorik pasien post stroke dengan merangsang neuroplastisitas pada berbagai area otak sehingga memperlancar peningkatan O2, glukosa dan berbagai metabolit yang mengarah ke peningkatan metabolisme regional melalui dilatasi arteriol serebral dan kapiler. Motor Imagery (MI) yang diberikan secara rutin akan membantu pemulihan fungsi motorik pasien post stroke dan meningkatkan kemandirian pasien. Simpulan: MI memiliki banyak efektivitas pada rehabilitasi pasien post stroke Saran: MI dipandang perlu untuk diterapkan di rumah sakit yang ada di Indonesia. Kata kunci: motor imagery; stroke; rehabilitation

2019 ◽  
Vol 26 (7) ◽  
pp. 548-553 ◽  
Author(s):  
Tácia Cotinguiba Machado ◽  
Adriani Andrade Carregosa ◽  
Matheus S. Santos ◽  
Nildo Manoel da Silva Ribeiro ◽  
Ailton Melo

2017 ◽  
Vol 27 (1) ◽  
pp. 107-137 ◽  
Author(s):  
A. A. Frolov ◽  
Dušan Húsek ◽  
E. V. Biryukova ◽  
P. D. Bobrov ◽  
O. A. Mokienko ◽  
...  

Author(s):  
Andrea Zimmermann-Schlatter ◽  
Corina Schuster ◽  
Milo A Puhan ◽  
Ewa Siekierka ◽  
Johann Steurer

2021 ◽  
Vol 23 (1) ◽  
pp. 40
Author(s):  
Deny Arifianto

Abstract Stroke or nerve function disorders caused by disruption of blood flow to the brain that arises suddenly or quickly with symptoms or signs that correspond to the affected area. One of the post-stroke rehabilitation using electrical stimulation, also known as an electro stimulator. This study aims to design Functional electrical stimulation (FES), which aims to stimulate the peripheral nervous system with biphasic pulses. Stimulation for patients with MMT 1 was optimal at a frequency of 22-30 Hz. In post-stroke patients with MMT inclusion characteristics 0-3, a minimum voltage, frequency and pulse width value of 200 Vp, 22 Hz, and 20 s is required with a power of 0.00146 Watt. Studies have shown that this electro stimulator device had good accuracy and has high peak voltage values and low effective current. It can be considered because it provides comfort and safety for medical therapy equipment. 


Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Jonathan Singer ◽  
Alyssa Conigliaro ◽  
Elizabeth Spina ◽  
Susan Law ◽  
Steven Levine

Background: Central Post Stroke Pain (CPSP) is reportedly due to strokes in the thalamic region (Dishinbition Theory); however, the Central Imbalance Theory states that CPSP is due to damage to the spinothalamic pathway (STP). Aims: 1) Clarify the role of thalamic strokes and STP damage in CPSP patients. 2) Gain a current understanding of anatomic substrates, brain imaging, and treatment of CPSP. Methods: Two independent reviewers systematically reviewed PUBMED, CINAHL and Web of Science for studies including original, clinical studies and randomized controlled trials (RCTs) using PRISMA guidelines. Studies had to assess CPSP, using a single question or pain scale. Results: Search from January – July 2016, identifying 731 publications. We extracted data from 23 studies and categorized the articles’ aims into 4 sections: somatosensory deficits (5 studies), STP (3 studies), brain imaging (7 studies), and RCTs (8 studies). Somatosensory studies showed high rates of CPSP; however, the underlying causes of these deficits were unclear. Most studies did not refer to stroke location as playing a role in CPSP, but that pathways may. STP studies displayed consistent evidence that the STP plays a major role in CPSP, delineating that CPSP can occur even when the stroke is not in the thalamic region but in other regions (e.g. cerebellum, basal ganglia, medulla). Four of the brain imaging studies found CPSP not related and 3 found it was related to thalamic strokes. All 7 studies had major limitations including sample size, no control groups, and selection bias. RCTs were mostly negative, but brain stem and motor cortex stimulation studies showed the most promise. Conclusions: While CPSP has been linked to the thalamic region since the early 1900’s, the peer-reviewed literature showed equivocal results when examining location of stroke. Our systematic review suggests damage to the STP is associated with CPSP and this could provide insights into mechanisms and treatment. Moreover, historical connection of strokes in the thalamic region and CPSP should be reevaluated as many studies noted that strokes in other regions of the brain also produce CPSP.


Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Hetal Mistry ◽  
Madeline Levy ◽  
Meaghan Roy-O'Reilly ◽  
Louise McCullough

Background and Purpose: Orosomucoid-1 (ORM-1) is an abundant protein with important roles in inflammation and immunosuppression. We utilized RNA sequencing to measure mRNA levels in human ischemic stroke patients, with confirmation by serum ORM-1 protein measurements. A mouse model of ischemic stroke was then used to examine post-stroke changes in ORM-1 within the brain itself. Hypothesis: We tested the hypothesis that ORM-1 levels increase following ischemic stroke, with sex differences in protein dynamics over time. Methods: RNA sequencing was performed on whole blood from ischemic stroke patients (n=23) and controls (n=12), with Benjamini-Hochberg correction for multiple testing. Enzyme-linked immunosorbent assay was performed on serum from ischemic stroke patients (n=28) and controls (n=8), with analysis by T-test. For brain analysis, mice (n=14) were subjected to a 90-minute middle cerebral artery occlusion (MCAO) surgery and sacrificed 6 or 24 hours after stroke. Control mice underwent parallel “sham” surgery without occlusion. Western blotting was used to detect ORM-1 protein levels in whole brain, with analysis by two-way ANOVA. Results: RNA sequencing showed a 2.8-fold increase in human ORM-1 at 24 hours post-stroke (q=.0029), an increase also seen in serum ORM-1 protein levels (p=.011). Western blot analysis of mouse brain revealed that glycosylated (p=0.0003) and naive (p=0.0333) forms of ORM-1 were higher in female mice compared to males 6 hours post-stroke. Interestingly, ORM-1 levels were higher in the brains of stroke mice at 6 hours (p=.0483), while at 24 hours ORM-1 levels in stroke mice were lower than their sham counterparts (p=.0212). In both human and mouse data, no sex differences were seen in ORM-1 levels in the brain or periphery at 24 hours post-stroke. Conclusion: In conclusion, ORM-1 is a sexually dimorphic protein involved in the early (<24 hour) response to ischemic stroke. This research serves as an initial step in determining the mechanism of ORM-1 in the ischemic stroke response and its potential as a future therapeutic target for both sexes.


2018 ◽  
Vol 2 (S1) ◽  
pp. 17-17
Author(s):  
Joseph B. Humphries ◽  
David T. Bundy ◽  
Eric C. Leuthardt ◽  
Thy N. Huskey

OBJECTIVES/SPECIFIC AIMS: The objective of this study is to determine the degree to which the use of a contralesionally-controlled brain-computer interface for stroke rehabilitation drives change in interhemispheric motor cortical activity. METHODS/STUDY POPULATION: Ten chronic stroke patients were trained in the use of a brain-computer interface device for stroke recovery. Patients perform motor imagery to control the opening and closing of a motorized hand orthosis. This device was sent home with patients for 12 weeks, and patients were asked to use the device 1 hour per day, 5 days per week. The Action Research Arm Test (ARAT) was performed at 2-week intervals to assess motor function improvement. Before the active motor imagery task, patients were asked to quietly rest for 90 seconds before the task to calibrate recording equipment. EEG signals were acquired from 2 electrodes—one each centered over left and right primary motor cortex. Signals were preprocessed with a 60 Hz notch filter for environmental noise and referenced to the common average. Power envelopes for 1 Hz frequency bands (1–30 Hz) were calculated through Gabor wavelet convolution. Correlations between electrodes were then calculated for each frequency envelope on the first and last 5 runs, thus generating one correlation value per subject, per run. The chosen runs approximately correspond to the first and last week of device usage. These correlations were Fisher Z-transformed for comparison. The first and last 5 run correlations were averaged separately to estimate baseline and final correlation values. A difference was then calculated between these averages to determine correlation change for each frequency. The relationship between beta-band correlation changes (13–30 Hz) and the change in ARAT score was determined by calculating a Pearson correlation. RESULTS/ANTICIPATED RESULTS: Beta-band inter-electrode correlations tended to decrease more in patients achieving greater motor recovery (Pearson’s r=−0.68, p=0.031). A similar but less dramatic effect was observed with alpha-band (8–12 Hz) correlation changes (Pearson’s r=−0.42, p=0.22). DISCUSSION/SIGNIFICANCE OF IMPACT: The negative correlation between inter-electrode power envelope correlations in the beta frequency band and motor recovery indicates that activity in the motor cortex on each hemisphere may become more independent during recovery. The role of the unaffected hemisphere in stroke recovery is currently under debate; there is conflicting evidence regarding whether it supports or inhibits the lesioned hemisphere. These findings may support the notion of interhemispheric inhibition, as we observe less in common between activity in the 2 hemispheres in patients successfully achieving recovery. Future neuroimaging studies with greater spatial resolution than available with EEG will shed further light on changes in interhemispheric communication that occur during stroke rehabilitation.


2021 ◽  
Author(s):  
Sergio Marin ◽  
Mateu Serra-Prat ◽  
Omar Ortega ◽  
Pere Clavé

Abstract Background and purpose: Oropharyngeal Dysphagia (OD) affects 40-81% of patients after stroke. A recent systematic review on the costs of OD and it’s main complications showed higher acute and long-term costs for those patients who developed OD, malnutrition and pneumonia after stroke. These results suggest that appropriate management of post-stroke OD could lead to reduction of clinical complications and significant cost savings. The purpose of this systematic review is to assess the available literature exploring the efficiency or cost-effectiveness of available healthcare interventions on the appropriate management of OD. Methods: A systematic review on economic evaluations of health care interventions on post-stroke patients with OD following PRISMA recommendations will be performed. MEDLINE, Embase, the National Health Service Economic Evaluation Database and the Cost-Effectiveness Analysis Registry Database will be searched and a subsequent reference check will be done. English and Spanish literature will be included without date restrictions. Studies will be included if they refer to economic evaluations or studies in which cost savings were reported in post-stroke patients suffering OD. Studies will be excluded if they are partial economic evaluation studies, if they refer to esophageal dysphagia, or if OD is caused by causes different from stroke. Evidence will be presented and synthetized with a narrative method and using tables. Quality evaluation will be done using Consolidated Health Economic Evaluation Reporting Standards (CHEERS) Statement. Discussion: The protocol for this systematic review is the first step to assess the cost-effectiveness of the healthcare interventions that have been described as potential treatments for post-stroke OD. This systematic review will summarize the current evidence on the relation between cost and benefits associated with the appropriate management of OD in post-stroke patients. Systematic review registration: PROSPERO CRD42020136245


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