scholarly journals Synthesis and Discovery of Schiff Base Bearing Furopyrimidinone for Selective Recognition of Zn2+ and its Applications in Cell Imaging and Detection of Cu2+

2021 ◽  
Vol 9 ◽  
Author(s):  
Yanggen Hu ◽  
Chao Luo ◽  
Lili Gui ◽  
Jing Lu ◽  
Juncai Fu ◽  
...  
Keyword(s):  
Schiff Base ◽  
Wittig Reaction ◽  
Limit Of Detection ◽  
Theoretical Calculations ◽  
Fluorescence Emission ◽  
Spectroscopic Studies ◽  
Cooperative Interaction ◽  
Fluorescence Sensing ◽  
Ft Ir ◽  
Binding Mechanisms

A simplefuro [2,3-d]pyrimidinone-based Schiff base FPS was synthesized via aza-Wittig reaction and structure elucidation was carried out by spectroscopic studies FT-IR, 1H NMR, and 13C NMR and mass spectrometry. FPS showed weak fluorescence emission in methanol and the selectivity of FPS to different metal ions (Mn2+, Ca2+, Fe2+, Fe3+, Mg2+, Al3+, Ba2+, Ag+, Co2+, Na+, K+, Cu2+, Zn2+, Pb2+, Bi3+) were studied by absorption and fluorescence titration. The results show that FPS has selective fluorescence sensing behavior for Zn2+ ions and the limit of detection (LOD) was calculated to be 1.19 × 10–8 mol/L. Moreover, FPS-Zn2+ acts as a metal based highly selective and sensitive new chemosensor for Cu2+ ions and the LOD was calculated to be 2.25 × 10–7 mol/L. In accordance with the results and theoretical calculations, we suspected that the binding mechanisms of FPS to Zn2+ and Cu2+ were assigned to be the cooperative interaction of Zn2+(Cu2+)-N.

scholarly journals Preparation of Quantum Dot-Embedded Photonic Crystal Hydrogel and Its Application as Fluorescence Sensor for the Detection of Nitrite

Nanomaterials ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3126
Author(s):  
Rongzhen Li ◽  
Lian Li ◽  
Bin Wang ◽  
Liping Yu
Keyword(s):  
Crystal Structure ◽  
Photonic Crystal ◽  
Limit Of Detection ◽  
Fluorescence Emission ◽  
Fluorescence Sensor ◽  
Photonic Crystal Structure ◽  
Polymerization Process ◽  
Enhancement Effect ◽  
Fluorescence Sensing ◽  
Cds Qds

The development of fluorescence sensing platforms with excellent photoluminescence capabilities is of great importance for their further application. In this work, a photonic crystal structure was successfully applied to enhance the luminescence performance of fluorescent hydrogel, and the application of the obtained hydrogel as a fluorescence sensor was explored. A polystyrene photonic crystal template was constructed via vertical deposition self-assembly; then, the precursor solution containing polyethylenimine-capped CdS quantum dots (PEI-CdS QDs) and monomers filled in the gap of the template. After the polymerization process, the desired hydrogel was obtained. PEI-CdS QDs endowed the hydrogel with its fluorescence property, while interestingly, the photonic crystal structure showed a significant enhancement effect on the fluorescence-emission capability. The mechanism of this phenomenon was revealed. Moreover, this hydrogel could be used as a reusable fluorescence sensor for the detection of nitrite in water with good selectivity. The limit of detection was determined to be 0.25 μmol/L, which is much lower than the maximum limit for nitrite in drinking water.

scholarly journals Surface-modified Colloid CdTe/CdS Quantum Dots by a Biocompatible Thiazolidine Derivative as Promising Platform for Immobilization of Glucose Oxidase: Application to Fluorescence Sensing of Glucose

2021 ◽  
Author(s):  
Rahman Hallaj ◽  
Zahra Hosseinchi
Keyword(s):  
Quantum Dots ◽  
Glucose Oxidase ◽  
Limit Of Detection ◽  
Low Cost ◽  
Fluorescence Emission ◽  
Cds Quantum Dots ◽  
Fluorescence Sensing ◽  
Experimental Conditions ◽  
Glucose Determination ◽  
Cds Qds

Abstract This work focuses on the synthesis of novel modified core-shell CdTe/CdS quantum dots (QDs) and develops as a fluorescence sensor for glucose determination. The (E)-2,2'-(4,4'-dioxo-2,2'-dithioxo-2H,2'H-[5,5'-bithiazolylidene]-3,3'(4H,4'H)-diyl)bis(3- mercaptopropanoic acid) (DTM) as a new derivative of thiazolidine was synthesized and characterized and used to surface-modification of CdTe/CdS QDs. DTM-capped CdTe/CdS QDs used to immobilization of glucose oxidase (GOD). The intensity fluorescence emission of the CdSe/CdS-DTM/GOD is highly sensitive to the concentration of H2O2 as a byproduct of the catalytic oxidation of glucose. The experimental results showed that the quenched fluorescence was proportional to the glucose concentration within the range of 10 nM − 0.32 µM under optimized experimental conditions. The limit of detection of this system was found to be 4.3 nM. Compared with most of the existing methods, this newly developed system possesses many advantages, including simplicity, low cost, and good sensitivity.

Fluorescence sensing and intracellular imaging of Pd2+ ions by a novel coumarinyl-rhodamine Schiff base

2019 ◽  
Vol 43 (9) ◽  
pp. 3899-3906 ◽  
Author(s):  
Arup Kumar Adak ◽  
Rakesh Purkait ◽  
Saikat Kumar Manna ◽  
Bankim Chandra Ghosh ◽  
Sudipta Pathak ◽  
...  
Keyword(s):  
Schiff Base ◽  
Limit Of Detection ◽  
Fluorescence Sensing ◽  
Intracellular Imaging ◽  
Hepes Buffer ◽  
Selective Sensor

Coumarinyl-rhodamine, HCR, served as an extremely selective sensor for Pd2+ ions in ethanol/H2O (8 : 2, v/v, HEPES buffer, pH 7.2) solution and the limit of detection (LOD) was 18.8 nM (3σ method).

scholarly journals Theoretical and Spectroscopic Studies of SN Donor Thiosemicarbazone Ligand and Its Pt(II) Complex

2021 ◽  
Vol 20 (1) ◽  
pp. 113-117
Author(s):  
Amna Qasem Ali ◽  
Boubaker Hosouna ◽  
Khadija Abdusslam Ahmida ◽  
Abdulasalam Amhamed Mohamed Alshreef
Keyword(s):  
Schiff Base ◽  
Schiff Base Ligand ◽  
Spectroscopic Studies ◽  
Azomethine Nitrogen ◽  
Nmr Analysis ◽  
Thiosemicarbazone Ligand ◽  
Elemental Analyses ◽  
Ft Ir ◽  
Theoretical Results ◽  
Good Agreement

Sulphur-nitrogen(SN) donor thiosemicarbazone ligand [(Z)-N-ethyl-2-(5-methyl-2-oxoindolin-3-ylidene)hydrazinecarbothioamide] and its Pt(II) complex were synthesized by condensation method. The compounds were structurally characterized by elemental analysis CHNS, FT-IR, and NMR analysis. The elemental analyses data for the compounds were in good agreement with the theoretical values.  The melting point of the complex was higher than the ligand, as expected. The FT-IR spectral data reflect a bidentate bonding of thiosemicarbazone ligand to Pt(II) ion through thioketo sulfur and azomethine nitrogen. The docking results (theoretical results) of these compounds show that the binding energy between DNA and Pt(II) complex was found to be less than that of the Schiff base ligand (L) in the sense that it has higher stability at various stages and angles. The strength of docking between DNA and Pt(II) complex was also found to be that stronger than the Schiff base ligand (L).

scholarly journals Molecular docking and multitudinous spectroscopic studies to elucidating proton-pump inhibitor a lansoprazole binding interaction with bovine serum albumin

2019 ◽  
Vol 9 (4) ◽  
pp. 4015-4021
Keyword(s):  
Proton Pump Inhibitor ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Proton Pump ◽  
Bovine Serum ◽  
Fluorescence Emission ◽  
Spectroscopic Studies ◽  
Binding Interaction ◽  
Ft Ir ◽  
Bsa Interaction

A carrier protein called bovine serum albumin (BSA) interaction with proton-pump inhibitor such as lansoprazole (LSE) has been investigated at 295, 303 and 311 K in pH 7.40 by docking and [UV–vis, CD, FT–IR and fluorescence (emission, 3D and synchronous)] spectroscopic studies. Emission fluorescence has suggested LSE BSA complex formation by static quenching with strong binding. This interaction has proceeded by Vander Waals and hydrogen bonding. An observation from competitive site marker and docking experiments has resulted in binding of LSE with BSA transpired at site II, whereas from Förster’s theory a binding distance ( ) was retrieved to be 0.19 Å from LSE to Trp of BSA. Change in conformation, secondary structure and microenvironment of BSA were noticed after LSE interaction. Diminished binding constant in Zn2+, Na+, Fe2+, Ca2+ and Co2+ ions presence on LSE-BSA interaction was also identified.

scholarly journals Complexation of Bis-2-(benzylideneamino)Phenol to Cobalt(II) and Zinc(II), and their Spectroscopic Studies

1970 ◽  
Vol 3 (1) ◽  
pp. 26-34
Author(s):  
Meng Guan Tay ◽  
Zainab Ngaini ◽  
Maya Asyikin Mohd Arif ◽  
Norazilawati Muhamad Sarih ◽  
Wan M. Khairul ◽  
...  
Keyword(s):  
Schiff Base ◽  
Absorption Band ◽  
Condensation Reaction ◽  
Spectroscopic Studies ◽  
Imine Nitrogen ◽  
Vis Spectroscopy ◽  
Ft Ir ◽  
Metal Ratio

A bis-Schiff base of bis-2-(benzylideneamino)phenol (SB1) was synthesized via condensation reaction ofterephthaldehyde and 2-aminophenol in ethanol. SB1 was then reacted with respective MX2 salt (M = Co & Zn,X = Cl & OAc) in the ligand to metal ratio of 1:2 under refluxing condition in ethanolic KOH solution for sixhours. All synthesized complexes were characterized using FT-IR and UV-vis spectroscopy. The formation ofcomplexes with Co and Zn was indicated by the shifts observed from the IR peaks and λmax of the UV absorptionbands for the C=N bond. The IR peak at 1621 cm-1 in SB1 was shifted to around 1638 and 1619 cm-1 afterforming its complexes with Co and Zn, respectively. The absorption band of C=N bond was blue shifted fromλmax of 384 nm to 307 nm in Co(II) complex, whereas this band was red-shifted to 389 nm in the Zn(II) complex.Therefore, SB1 was confirmed to coordinate with the Co(II) and Zn(II) metal centres via the imine nitrogen.

scholarly journals [5]Helicene-Scaffold Fluorescence Sensing for Selective Detection of Au3+ Ions and Gold Nanoparticle

2021 ◽  
Author(s):  
Pichayanun Sinthuprasert ◽  
Anuwut Petdum ◽  
Pattanawit Swanglap ◽  
Waraporn Panchan ◽  
Thanasat Sooksimuang ◽  
...  
Keyword(s):  
Limit Of Detection ◽  
Photophysical Properties ◽  
Stokes Shift ◽  
Fluorescence Emission ◽  
Fluorescence Sensing ◽  
High Productivity ◽  
Real Water Samples ◽  
Detection Response ◽  
High Fluorescence ◽  
Anhydride Derivative

A new quenching fluorescence sensor (MDP) with high productivity was easily synthesized from a [5]helicene anhydride derivative and propargyl bromide. This MDP sensor has significant photophysical properties, including high fluorescence emission and a large Stokes shift, and it exhibits selectivity and an excellent detection response in distinguishing Au3+ ions from interfering metal ions in aqueous solution. The limit of detection of the sensor were determined to be 0.16 µmol L-1 or 32.0 ppb. Stoichiometric binding between the MDP and Au3+ ions was found to occur at a 1:2 ratio. Additionally, the MDP sensor shows an ability to detect gold ions in real water samples and recognize gold nanoparticles (AuNPs), which invites its further application in biological and environmental systems.

Green Synthesis and Spectroscopic Studies of Ag-rGO Nanocomposites for Highly Selective Mercury (II) Sensing

2018 ◽  
Vol 9 (1) ◽  
pp. 101-108 ◽  
Author(s):  
Shubhangi J. Mane-Gavade ◽  
Sandip R. Sabale ◽  
Xiao-Ying Yu ◽  
Gurunath H. Nikam ◽  
Bhaskar V. Tamhankar
Keyword(s):  
Green Synthesis ◽  
Color Change ◽  
Limit Of Detection ◽  
Aqueous Media ◽  
Suitable Condition ◽  
Cost Effective ◽  
Spectroscopic Studies ◽  
Calibration Plot ◽  
First Time

Introduction: Herein we report the green synthesis and characterization of silverreduced graphene oxide nanocomposites (Ag-rGO) using Acacia nilotica gum for the first time. Experimental: We demonstrate the Hg2+ ions sensing ability of the Ag-rGO nanocomposites form aqueous medium. The developed colorimetric sensor method is simple, fast and selective for the detection of Hg2+ ions in aqueous media in presence of other associated ions. A significant color change was noticed with naked eye upon Hg2+ addition. The color change was not observed for cations including Sr2+, Ni2+, Cd2+, Pb2+, Mg2+, Ca2+, Fe2+, Ba2+ and Mn2+indicating that only Hg2+ shows a strong interaction with Ag-rGO nanocomposites. Under the most suitable condition, the calibration plot (A0-A) against concentration of Hg2+ was linear in the range of 0.1-1.0 ppm with a correlation coefficient (R2) value 0.9998. Results & Conclusion The concentration of Hg2+ was quantitatively determined with the Limit of Detection (LOD) of 0.85 ppm. Also, this method shows excellent selectivity towards Hg2+ over nine other cations tested. Moreover, the method offers a new cost effective, rapid and simple approach for the detection of Hg2+ in water samples.

scholarly journals A Compact Detection Platform Based on Gradient Guided-Mode Resonance for Colorimetric and Fluorescence Liquid Assay Detection

Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2797
Author(s):  
Jing-Jhong Gao ◽  
Ching-Wei Chiu ◽  
Kuo-Hsing Wen ◽  
Cheng-Sheng Huang
Keyword(s):  
Limit Of Detection ◽  
Detection System ◽  
Fluorescence Emission ◽  
Assay Sensitivity ◽  
Detection Range ◽  
Current Form ◽  
Guided Mode ◽  
Spectral Detection ◽  
Guided Mode Resonance ◽  
Colorimetric Assays

This paper presents a compact spectral detection system for common fluorescent and colorimetric assays. This system includes a gradient grating period guided-mode resonance (GGP-GMR) filter and charge-coupled device. In its current form, the GGP-GMR filter, which has a size of less than 2.5 mm, can achieve a spectral detection range of 500–700 nm. Through the direct measurement of the fluorescence emission, the proposed system was demonstrated to detect both the peak wavelength and its corresponding intensity. One fluorescent assay (albumin) and two colorimetric assays (albumin and creatinine) were performed to demonstrate the practical application of the proposed system for quantifying common liquid assays. The results of our system exhibited suitable agreement with those of a commercial spectrometer in terms of the assay sensitivity and limit of detection (LOD). With the proposed system, the fluorescent albumin, colorimetric albumin, and colorimetric creatinine assays achieved LODs of 40.99 and 398 and 25.49 mg/L, respectively. For a wide selection of biomolecules in point-of-care applications, the spectral detection range achieved by the GGP-GMR filter can be further extended and the simple and compact optical path configuration can be integrated with a lab-on-a-chip system.

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