scholarly journals Histopathology-Based Deep-Learning Predicts Atherosclerotic Lesions in Intravascular Imaging

2021 ◽  
Vol 8 ◽  
Author(s):  
Olle Holmberg ◽  
Tobias Lenz ◽  
Valentin Koch ◽  
Aseel Alyagoob ◽  
Léa Utsch ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Deep Learning ◽  
Expert Knowledge ◽  
Learning Algorithm ◽  
Atherosclerotic Lesion ◽  
Prediction Algorithm ◽  
Optical Coherence ◽  
Data Set ◽  
Deep Learning Algorithm ◽  
Atherosclerotic Lesions

Background: Optical coherence tomography is a powerful modality to assess atherosclerotic lesions, but detecting lesions in high-resolution OCT is challenging and requires expert knowledge. Deep-learning algorithms can be used to automatically identify atherosclerotic lesions, facilitating identification of patients at risk. We trained a deep-learning algorithm (DeepAD) with co-registered, annotated histopathology to predict atherosclerotic lesions in optical coherence tomography (OCT).Methods: Two datasets were used for training DeepAD: (i) a histopathology data set from 7 autopsy cases with 62 OCT frames and co-registered histopathology for high quality manual annotation and (ii) a clinical data set from 51 patients with 222 OCT frames in which manual annotations were based on clinical expertise only. A U-net based deep convolutional neural network (CNN) ensemble was employed as an atherosclerotic lesion prediction algorithm. Results were analyzed using intersection over union (IOU) for segmentation.Results: DeepAD showed good performance regarding the prediction of atherosclerotic lesions, with a median IOU of 0.68 ± 0.18 for segmentation of atherosclerotic lesions. Detection of calcified lesions yielded an IOU = 0.34. When training the algorithm without histopathology-based annotations, a performance drop of >0.25 IOU was observed. The practical application of DeepAD was evaluated retrospectively in a clinical cohort (n = 11 cases), showing high sensitivity as well as specificity and similar performance when compared to manual expert analysis.Conclusion: Automated detection of atherosclerotic lesions in OCT is improved using a histopathology-based deep-learning algorithm, allowing accurate detection in the clinical setting. An automated decision-support tool based on DeepAD could help in risk prediction and guide interventional treatment decisions.

scholarly journals Assessment of a Segmentation-Free Deep Learning Algorithm for Diagnosing Glaucoma From Optical Coherence Tomography Scans

2020 ◽  
Vol 138 (4) ◽  
pp. 333 ◽  
Author(s):  
Atalie C. Thompson ◽  
Alessandro A. Jammal ◽  
Samuel I. Berchuck ◽  
Eduardo B. Mariottoni ◽  
Felipe A. Medeiros
Keyword(s):  
Optical Coherence Tomography ◽  
Deep Learning ◽  
Learning Algorithm ◽  
Optical Coherence ◽  
Deep Learning Algorithm

scholarly journals Identification of Coronary Calcifications in Optical Coherence Tomography Imaging Using Deep Learning

2020 ◽  
Author(s):  
Yarden Avital ◽  
Akiva Madar ◽  
Shlomi Arnon ◽  
Edward Koifman
Keyword(s):  
Optical Coherence Tomography ◽  
Deep Learning ◽  
Learning Algorithm ◽  
Image Acquisition ◽  
Percutaneous Treatment ◽  
Optical Coherence ◽  
Optimal Method ◽  
Deep Learning Algorithm ◽  
Coronary Calcifications ◽  
Artery Disease

Abstract Coronary calcifications are an obstacle for successful percutaneous treatment of coronary artery disease patients. The optimal method for delineating calcifications extent is optical coherence tomography (coronary OCT). To identify calcification on OCT and subsequently tailor the appropriate treatment, requires expertise in both image acquisition and interpretation. Image acquisition consists from system calibration, blood clearance by a contrast agent along with synchronization of the pullback process. Accurate interpretation demands careful review by the operator of a segment of 50-75mm of the coronary vessel at steps of 0.5-1mm accounting for 75-100 images in each OCT run, which is time consuming and necessitates some expertise in OCT analysis.In this paper we developed a new deep learning algorithm to assist the physician to identify and quantify coronary calcifications promptly, efficiently and accurately. Our algorithm achieves an accuracy of 0.9903 ± 0.009 over the test set at size of 1500 frames and even managed to find calcifications that weren’t recognized manually by the physician. For the best knowledge of the authors our algorithm achieves high accuracy which was never achieved in the past.

scholarly journals Pattern Detection Model Using a Deep Learning Algorithm for Power Data Analysis in Abnormal Conditions

Electronics ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. 1140
Author(s):  
Jeong-Hee Lee ◽  
Jongseok Kang ◽  
We Shim ◽  
Hyun-Sang Chung ◽  
Tae-Eung Sung
Keyword(s):  
Big Data ◽  
Deep Learning ◽  
Short Term Memory ◽  
Learning Algorithm ◽  
Pattern Detection ◽  
Prediction Algorithm ◽  
Data Set ◽  
Detection Model ◽  
Deep Learning Algorithm ◽  
Abnormal Pattern

Building a pattern detection model using a deep learning algorithm for data collected from manufacturing sites is an effective way for to perform decision-making and assess business feasibility for enterprises, by providing the results and implications of the patterns analysis of big data occurring at manufacturing sites. To identify the threshold of the abnormal pattern requires collaboration between data analysts and manufacturing process experts, but it is practically difficult and time-consuming. This paper suggests how to derive the threshold setting of the abnormal pattern without manual labelling by process experts, and offers a prediction algorithm to predict the potentials of future failures in advance by using the hybrid Convolutional Neural Networks (CNN)–Long Short-Term Memory (LSTM) algorithm, and the Fast Fourier Transform (FFT) technique. We found that it is easier to detect abnormal patterns that cannot be found in the existing time domain after preprocessing the data set through FFT. Our study shows that both train loss and test loss were well developed, with near zero convergence with the lowest loss rate compared to existing models such as LSTM. Our proposition for the model and our method of preprocessing the data greatly helps in understanding the abnormal pattern of unlabeled big data produced at the manufacturing site, and can be a strong foundation for detecting the threshold of the abnormal pattern of big data occurring at manufacturing sites.

scholarly journals Identification of coronary calcifications in optical coherence tomography imaging using deep learning

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yarden Avital ◽  
Akiva Madar ◽  
Shlomi Arnon ◽  
Edward Koifman
Keyword(s):  
Optical Coherence Tomography ◽  
Deep Learning ◽  
Learning Algorithm ◽  
Image Acquisition ◽  
Percutaneous Treatment ◽  
Optical Coherence ◽  
Optimal Method ◽  
Deep Learning Algorithm ◽  
Coronary Calcifications ◽  
Artery Disease

AbstractCoronary calcifications are an obstacle for successful percutaneous treatment of coronary artery disease patients. The optimal method for delineating calcifications extent is coronary optical coherence tomography (OCT). To identify calcification on OCT and subsequently tailor the appropriate treatment, requires expertise in both image acquisition and interpretation. Image acquisition consists from system calibration, blood clearance by a contrast agent along with synchronization of the pullback process. Accurate interpretation demands careful review by the operator of a segment of 50–75 mm of the coronary vessel at steps of 5–10 frames per mm accounting for 375–540 images in each OCT run, which is time consuming and necessitates some expertise in OCT analysis. In this paper we developed a new deep learning algorithm to assist the physician to identify and quantify coronary calcifications promptly, efficiently and accurately. Our algorithm achieves an accuracy of 0.9903 ± 0.009 over the test set at size of 1500 frames and even managed to find calcifications that were not recognized manually by the physician. For the best knowledge of the authors our algorithm achieves high accuracy which was never achieved in the past.

Ensemble-based deep meta learning for medical image segmentation

2021 ◽  
pp. 1-7
Author(s):  
Usman Ahmed ◽  
Jerry Chun-Wei Lin ◽  
Gautam Srivastava
Keyword(s):  
Image Segmentation ◽  
Deep Learning ◽  
Learning Algorithm ◽  
State Of The Art ◽  
Medical Image Segmentation ◽  
The State ◽  
Data Set ◽  
Deep Learning Algorithm ◽  
Meta Learning ◽  
Small Set

Deep learning methods have led to a state of the art medical applications, such as image classification and segmentation. The data-driven deep learning application can help stakeholders to collaborate. However, limited labelled data set limits the deep learning algorithm to generalize for one domain into another. To handle the problem, meta-learning helps to learn from a small set of data. We proposed a meta learning-based image segmentation model that combines the learning of the state-of-the-art model and then used it to achieve domain adoption and high accuracy. Also, we proposed a prepossessing algorithm to increase the usability of the segments part and remove noise from the new test image. The proposed model can achieve 0.94 precision and 0.92 recall. The ability to increase 3.3% among the state-of-the-art algorithms.

Using geometric constraints to improve performance of image classifiers for automatic segmentation of traffic signs

GEOMATICA ◽  
2021 ◽  
pp. 1-23
Author(s):  
Roholah Yazdan ◽  
Masood Varshosaz ◽  
Saied Pirasteh ◽  
Fabio Remondino
Keyword(s):  
Deep Learning ◽  
Learning Algorithm ◽  
Automatic Segmentation ◽  
Geometric Constraints ◽  
Support Vector ◽  
Svm Classifier ◽  
Data Set ◽  
Traffic Signs ◽  
Deep Learning Algorithm ◽  
Comparison Results

Automatic detection and recognition of traffic signs from images is an important topic in many applications. At first, we segmented the images using a classification algorithm to delineate the areas where the signs are more likely to be found. In this regard, shadows, objects having similar colours, and extreme illumination changes can significantly affect the segmentation results. We propose a new shape-based algorithm to improve the accuracy of the segmentation. The algorithm works by incorporating the sign geometry to filter out the wrong pixels from the classification results. We performed several tests to compare the performance of our algorithm against those obtained by popular techniques such as Support Vector Machine (SVM), K-Means, and K-Nearest Neighbours. In these tests, to overcome the unwanted illumination effects, the images are transformed into colour spaces Hue, Saturation, and Intensity, YUV, normalized red green blue, and Gaussian. Among the traditional techniques used in this study, the best results were obtained with SVM applied to the images transformed into the Gaussian colour space. The comparison results also suggested that by adding the geometric constraints proposed in this study, the quality of sign image segmentation is improved by 10%–25%. We also comparted the SVM classifier enhanced by incorporating the geometry of signs with a U-Shaped deep learning algorithm. Results suggested the performance of both techniques is very close. Perhaps the deep learning results could be improved if a more comprehensive data set is provided.

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