scholarly journals Relative Children’s Lipid Accumulation Product Is a Novel Indicator for Metabolic Syndrome

2021 ◽  
Vol 12 ◽  
Author(s):  
Li Zhang ◽  
Zizhe Zhang ◽  
Bangxuan Wang ◽  
Yongting Yuan ◽  
Lili Sun ◽  
...  

BackgroundThe children’s lipid accumulation product (CLAP) is associated with MS in Chinese children and adolescents. The aim of this study was to develop a more effective indicator, the relative children's lipid accumulation product (RCLAP) was evaluated for correlation with MS and the density of lipid accumulation.MethodsA stratified cluster sampling method was used to recruit 683 students aged 8–15 years in this study. The presence of MS was defined according to the NCEP-ATP III criteria. The participants’ guardians signed informed consent before the medical examination. This study was approved by the Medical Ethics Committee of the Bengbu Medical College [(2015) No.003] and was conducted in accordance with the Declaration of Helsinki.ResultsThe overall prevalence of MS was 4.8% (male 6.6%, female 2.8%). After adjusting for sedentary activity time, relative children's lipid accumulation product per height (RCLAP-H) and relative children's lipid accumulation product per sitting height (RCLAP-SH) significantly increased the risk of MS in girls [OR (95% CI): 96.13 (11.11–831.97) and 96.13 (11.11–831.97), respectively]. After adjusting for ages and moderate-to-vigorous physical activity time, RCLAP-H, and RCLAP-SH significantly increased the risk of MS in boys [OR (95% CI): 171.75 (33.60–878.00) and 133.18 (27.65–641.39), respectively]. The AUCs of RCLAP-H and RCLAP-SH for predicting MS were 0.950, 0.948 in girls, and 0.952, 0.952 in boys, which were higher than BMI, WHtR, Tg/HDL-C, CLAP, and CLAP combining height, sitting height.ConclusionsThe RCLAP-H and RCLAP-SH were more effective indicators for predicting MS than BMI, WHtR, Tg/HDL-C, and CLAP in children and adolescents.

2020 ◽  
Author(s):  
Li Zhang ◽  
Zizhe Zhang ◽  
Bangxuan Wang ◽  
Yongting Yuan ◽  
Lili Sun ◽  
...  

Abstract BackgroundThe children’s lipid accumulation product (CLAP) was associated with MS in Chinese children and adolescents. The study was to develop a more effective indicator, relative children’s lipid accumulation product (RCLAP)associated with MS reflect the density of lipid accumulation among Chinese children and adolescents. MethodsA stratified cluster sampling method was used to recruit 683 students aged 8-15 years in this study. The presence of MS was defined according to the NCEP-ATP III criteria. The t-test, chi-square test, logistic regression models were used to analyze the associations of SBMI, SWHtR, SlnCLAP, SRCLAP-H, SRCLAP-SH, RCLAP-W with MS. Receiver Operating Characteristic (ROC) curves was used to evaluate the predictive efficiency of above indexes for predicting MS. ResultsThe overall prevalence of MS was 4.8% (boys 6.6%, girls 2.8%). In girls, after adjusting for sedentary activity time, WHtR, BMI, CLAP, RCLAP-H, RCLAP-SH and RCLAP-W significantly increased risk of MS (OR(95%CI):15.79 (3.15-79.21), 3.73 (0.87-15.95), Null, 96.13 (11.11-831.97), 96.13 (11.11-831.97), 18.28 (4.24-78.87), respectively). In boys, after adjusting for ages and moderate-to-vigorous physical activity time, WHtR, BMI, CLAP, RCLAP-H, RCLAP-SH and SRCLAP-W significantly increased risk of MS (OR(95%CI): 37.43(11.67-120.10), 68.33(18.51-252.20), 105.86(21.99-509.68), 171.75(33.60-878.00), 133.18(27.65-641.39), 50.13(15.48-162.37, respectively). The AUCs of RCLAP-H and RCLAP-SH for predicting MS were 0.950, 0.948 in girls, and 0.952, 0.952 in boys, which were higher than these of BMI, WHtR, CLAP and RCLAP-W.ConclusionThe relative children,s lipid accumulation products(RCLAP-H and RCLAP-SH ) were more effective indicators for predicting MS than BMI, WHtR and CLAP in Chinese children and adolescents.


2020 ◽  
Author(s):  
Bangxuan Wang ◽  
Yongting Yuan ◽  
Jingyao Hu ◽  
Lili Sun ◽  
Rongying Yao ◽  
...  

Abstract Background and aimsThe dyslipidemia contributed to more than half Cardiovascular disease (CVD) which ranked first in all causes of death in the world. Children’s lipid accumulation product (CLAP) is significantly related to cardiac metabolic risk factors in children and adolescents. The present study was to explore a novel indicator of children’s lipid accumulation product (CLAP) associated with dyslipidemia in Chinese children and adolescents.MethodsA total of 683 children and adolescents aged 8-15 years were recruited using the stratified cluster sampling method in this cross-sectional study, and were measured their body height, weight, waist circumference (WC), abdominal skinfold thickness (AST), triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), dietary behaviors and physical activities. A logistic regression model and receiver operating characteristic curve (ROC curve) were used to compare the effects of CLAP for predicting dyslipidemia.ResultsThe prevalence of dyslipidemia was 13.6% (13.9% in boys and 13.2% in girls). The AUC (95%CI) of CLAP for predicting dyslipidemia was 0.76 (0.66-0.84) in girls, was 0.83 (0.76-0.89) in boys, and was higher than those of Sweight, SWC, SAST, SWHtR, and SBMI, respectively. The P85 of CLAP was the optimal value to predict dyslipidemia among girls (OR (95% CI): 10.54(5.09-21.82), AUC (95% CI): 0.72 (0.62-0.81). The P75 of CLAP was the optimal value to predict dyslipidemia among boys (OR (95% CI): 8.74(4.54-16.85), AUC (95% CI): 0.73 (95% CI 0.65-0.81).ConclusionsThe CLAP was a novel indicator associated with dyslipidemia in Chinese children and adolescents, and performed better than weight, WC, AST, WHtR, and BMI.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zizhe Zhang ◽  
Li Zhang ◽  
Lili Sun ◽  
Bangxuan Wang ◽  
Yongting Yuan ◽  
...  

Abstract Background This study aimed to develop a novel indicator associated with hypertension in Chinese children and adolescents, the relative children’s lipid accumulation product (RCLAP). Methods A cross-sectional study was conducted in 2018. A total of 683 students aged 8–15 years were recruited via a stratified cluster sampling Methods. Anthropometric indexes (waist circumference (WC), Body mass index (BMI), Waist-height ratio (WHtR), logarithm children LAP (LnCLAP), RCLAP per height (RCLAP-H)) were standardized using a z-score method (standardized variables: SWC, SBMI, SWHtR, SLnCLAP, SRCLAP-H). A logistic regression model was performed to evaluate the association of the above indicators with the outcome of hypertension. Results The overall prevalence of hypertension was 5.7% (5.5% in boys, 6.0% in girls). SWC ≥ P75, SBMI ≥ P75, SWHtR ≥ P75, SlnCLAP ≥ P75 and SRCLAP-H ≥ P75 significantly increased risk of hypertension, with odds ratios (OR) of 2.21 (95% confidence interval (CI): 1.13, 4.30), 2.30 (1.18, 4.49), 2.64 (1.35, 5.14), 4.43 (2.28, 8.61), and 4.49 (2.31, 8.71), respectively. Conclusion RCLAP is a novel indicator associated with hypertension in Chinese children and adolescents, and it performs better than WC, BMI, WHtR and children LAP.


2020 ◽  
Vol 114 (5) ◽  
pp. 421-431
Author(s):  
Jing Qi ◽  
Wen Hong Xu ◽  
Li Juan Wang ◽  
Qi Di Li

Introduction: Physical activity is a key component of a healthy lifestyle for youths with visual impairments (i.e., blindness or low vision). This study aims to examine the habitual physical activity and sedentary time of Chinese children and adolescents with visual impairments and to determine whether age, gender, and body composition significantly influence their behavior. Methods: A purposeful sample method was utilized to recruit 137 Chinese youths with visual impairments from a special school for individuals with visual and hearing impairments. A total of 72 students with visual impairments (aged 7–17 years; M age = 13.4) participated in this study. ActiGraph GT3X accelerometers were used to measure the habitual physical activity and sedentary time. Results: Youths with visual impairments in this study spent an average of 287.86 (standard deviation [ SD] = 45.67) minutes of light physical activity, 146.79 ( SD = 56.95) minutes of moderate physical activity, 18.47 ( SD = 15.15) minutes of vigorous physical activity, 165.26 ( SD = 69.83) minutes of moderate-to-vigorous-intensity physical activity, and 979.51 ( SD = 109.10) minutes of sedentary time per day. Children with visual impairments in elementary school engaged in more habitual physical activity and had less sedentary time than did students in middle and high school. Differences in gender and body composition with regard to time spent being active or sedentary were insignificant. Discussion: Findings demonstrated that Chinese youths with visual impairments in this study had sufficient health-enhancing physical activity and were habitually active. Future research is needed to identify the factors that account for the high habitual physical activity levels of Chinese youths with visual impairments. Implications for practitioners: Transition planning for students with visual impairments to facilitate active habitual physical activity participation when children grow up is warranted.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Feng Zhang ◽  
Cunjian Bi ◽  
Xiaojian Yin ◽  
Qi Chen ◽  
Yuqiang Li ◽  
...  

AbstractTo develop age- and sex-specific physical fitness reference standards and express the age- and sex-related differences using standardized effect sizes for Chinese children and adolescents. A total of 85,535 children and adolescents (48.7% girls) aged 7–18 years were recruited from six geographical divisions of China using a stratified randomized cluster sampling method. Seven physical fitness items including grip strength, standing long jump, 30-s sit-ups, sit and reach, 50-m dash, 20-s repeated straddling, and 20-m SRT were measured following a standardized procedure. Percentile curves for each physical fitness test were calculated using the LMS. Age- and sex-related differences were expressed as standardized effect sizes. We observed that the performance improved with age along with the analyzed percentiles in all tests. Boys had higher values compared to girls in all the physical fitness items except for sit and reach test, where girls showed better performance in all analyzed percentiles. Also, the sex differences increased with ages except sit and reach. There is a need for a differentiated approach in the physical education class in terms of adjustment of physical activity based on sex, level of fitness abilities in China.


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