scholarly journals Application of Machine Learning for Drug–Target Interaction Prediction

2021 ◽  
Vol 12 ◽  
Author(s):  
Lei Xu ◽  
Xiaoqing Ru ◽  
Rong Song
Keyword(s):  
Machine Learning ◽  
Drug Target ◽  
High Performance ◽  
Machine Learning Techniques ◽  
Future Research ◽  
Target Interaction ◽  
Interaction Prediction ◽  
Learning Techniques ◽  
Present Generation ◽  
Applications Of Machine Learning

Exploring drug–target interactions by biomedical experiments requires a lot of human, financial, and material resources. To save time and cost to meet the needs of the present generation, machine learning methods have been introduced into the prediction of drug–target interactions. The large amount of available drug and target data in existing databases, the evolving and innovative computer technologies, and the inherent characteristics of various types of machine learning have made machine learning techniques the mainstream method for drug–target interaction prediction research. In this review, details of the specific applications of machine learning in drug–target interaction prediction are summarized, the characteristics of each algorithm are analyzed, and the issues that need to be further addressed and explored for future research are discussed. The aim of this review is to provide a sound basis for the construction of high-performance models.

Applications of Machine Learning in Real-Time Tumor Localization

2012 ◽  
pp. 419-431
Author(s):  
Ruijiang Li ◽  
Steve B. Jiang
Keyword(s):  
Machine Learning ◽  
Real Time ◽  
Principal Component ◽  
Machine Learning Techniques ◽  
Future Research ◽  
Tumor Localization ◽  
Linear Discriminant ◽  
Learning Techniques ◽  
Domain Specific Knowledge ◽  
Applications Of Machine Learning

Recently, machine learning has gained great popularity in many aspects of radiation therapy. In this chapter, the authors will demonstrate the applications of various machine learning techniques in the context of real-time tumor localization in lung cancer radiotherapy. These cover a wide range of well established machine learning techniques, including principal component analysis, linear discriminant analysis, artificial neural networks, and support vector machine, etc. Respiratory gating, as a special case of tumor localization, will also be discussed. The chapter will demonstrate how domain specific knowledge and prior information can be useful in achieving more accurate and robust tumor localization. Future research directions in machine learning that can further improve the accuracy for tumor localization are also discussed.

scholarly journals Applications of Machine Learning to Reciprocating Compressor Fault Diagnosis: A Review

Processes ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 909
Author(s):  
Qian Lv ◽  
Xiaoling Yu ◽  
Haihui Ma ◽  
Junchao Ye ◽  
Weifeng Wu ◽  
...  
Keyword(s):  
Machine Learning ◽  
Fault Diagnosis ◽  
Research Direction ◽  
Machine Learning Techniques ◽  
Future Research ◽  
Reciprocating Compressor ◽  
Operating Condition ◽  
Practical Applications ◽  
Learning Techniques ◽  
Applications Of Machine Learning

Operating condition detection and fault diagnosis are very important for reliable operation of reciprocating compressors. Machine learning is one of the most powerful tools in this field. However, there are very few comprehensive reviews which summarize the current research of machine learning in monitoring reciprocating compressor operating condition and fault diagnosis. In this paper, the recent application of machine learning techniques in reciprocating compressor fault diagnosis is reviewed. The advantages and challenges in the detection process, based on three main monitoring parameters in practical applications, are discussed. Future research direction and development are proposed.

Role of Artificial Intelligence in Modeling Psychometrics to Detect Neurodevelopmental Disorders

2020 ◽  
pp. 213-227
Author(s):  
Navjot Singh ◽  
Amarjot Kaur
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Neurodevelopmental Disorders ◽  
Machine Learning Techniques ◽  
Diagnosis And Prognosis ◽  
Processing Power ◽  
Learning Techniques ◽  
Numerous Data ◽  
Applications Of Machine Learning ◽  
Micro Patterns

The objective of the present chapter is to highlight applications of machine learning and artificial intelligence (AI) in clinical diagnosis of neurodevelopmental disorders. The proposed approach aims at recognizing behavioral traits and other cognitive aspects. The availability of numerous data and high processing power, such as graphic processing units (GPUs) or cloud computing, enabled the study of micro-patterns hundreds of times faster compared to manual analysis. AI, being a new technological breakthrough, enables study of human behavior patterns, which are hidden in millions of micro-patterns originating from human actions, reactions, and gestures. The chapter will also focus on the challenges in existing machine learning techniques and the best possible solution addressing those problems. In the future, more AI-based expert systems can enhance the accuracy of the diagnosis and prognosis process.

Machine Learning

2012 ◽  
pp. 13-22 ◽  
Author(s):  
João Gama ◽  
André C.P.L.F. de Carvalho
Keyword(s):  
Machine Learning ◽  
Language Processing ◽  
Text Processing ◽  
Machine Learning Algorithms ◽  
Machine Learning Techniques ◽  
Background Information ◽  
Future Research ◽  
Personal View ◽  
Learning Techniques ◽  
Future Research Directions

Machine learning techniques have been successfully applied to several real world problems in areas as diverse as image analysis, Semantic Web, bioinformatics, text processing, natural language processing,telecommunications, finance, medical diagnosis, and so forth. A particular application where machine learning plays a key role is data mining, where machine learning techniques have been extensively used for the extraction of association, clustering, prediction, diagnosis, and regression models. This text presents our personal view of the main aspects, major tasks, frequently used algorithms, current research, and future directions of machine learning research. For such, it is organized as follows: Background information concerning machine learning is presented in the second section. The third section discusses different definitions for Machine Learning. Common tasks faced by Machine Learning Systems are described in the fourth section. Popular Machine Learning algorithms and the importance of the loss function are commented on in the fifth section. The sixth and seventh sections present the current trends and future research directions, respectively.

Machine Learning

2011 ◽  
pp. 2462-2468 ◽  
Author(s):  
João Gama ◽  
André C.P.L.F. de Carvalho
Keyword(s):  
Machine Learning ◽  
Language Processing ◽  
Text Processing ◽  
Machine Learning Algorithms ◽  
Machine Learning Techniques ◽  
Background Information ◽  
Future Research ◽  
Personal View ◽  
Learning Techniques ◽  
Future Research Directions

Machine learning techniques have been successfully applied to several real world problems in areas as diverse as image analysis, Semantic Web, bioinformatics, text processing, natural language processing,telecommunications, finance, medical diagnosis, and so forth. A particular application where machine learning plays a key role is data mining, where machine learning techniques have been extensively used for the extraction of association, clustering, prediction, diagnosis, and regression models. This text presents our personal view of the main aspects, major tasks, frequently used algorithms, current research, and future directions of machine learning research. For such, it is organized as follows: Background information concerning machine learning is presented in the second section. The third section discusses different definitions for Machine Learning. Common tasks faced by Machine Learning Systems are described in the fourth section. Popular Machine Learning algorithms and the importance of the loss function are commented on in the fifth section. The sixth and seventh sections present the current trends and future research directions, respectively.

Wind Speed Forecasting Using Innovative Regression Applications of Machine Learning Techniques

2021 ◽  
pp. 249-263
Author(s):  
Arash Moradzadeh ◽  
Amin Mansour-Saatloo ◽  
Morteza Nazari-Heris ◽  
Behnam Mohammadi-Ivatloo ◽  
Somayeh Asadi
Keyword(s):  
Machine Learning ◽  
Wind Speed ◽  
Machine Learning Techniques ◽  
Wind Speed Forecasting ◽  
Learning Techniques ◽  
Applications Of Machine Learning

Machine Learning Techniques to Identify and Characterize Sleep Disorders Using Biosignals

2021 ◽  
pp. 136-160
Author(s):  
Mercedes Barrachina ◽  
Laura Valenzuela López
Keyword(s):  
Machine Learning ◽  
Sleep Disorders ◽  
Adult Population ◽  
The United States ◽  
Machine Learning Techniques ◽  
Future Research ◽  
Research Directions ◽  
Learning Techniques ◽  
Control And Prevention ◽  
Future Research Directions

Sleep disorders are related to many different diseases, and they could have a significant impact in patients' health, causing an economic impact to the society and to the national health systems. In the United States, according to information from the Center for Disease Control and Prevention, those disorders are affecting 50-70 million in the adult population. Sleep disorders are causing annually around 40,000 deaths due to cardiovascular problems, and they cost the health system more than 16 billion. In other countries, such as in Spain, those disorders affect up to 48% of the adult population. The main objective of this chapter is to review and evaluate the different machine learning techniques utilized by researchers and medical professionals to identify, assess, and characterize sleep disorders. Moreover, some future research directions are proposed considering the evaluated area.

What is Machine Learning? A Primer for the Epidemiologist

2019 ◽  
Author(s):  
Qifang Bi ◽  
Katherine E Goodman ◽  
Joshua Kaminsky ◽  
Justin Lessler
Keyword(s):  
Machine Learning ◽  
Big Data ◽  
Computer Science ◽  
Research Methods ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Machine Learning Techniques ◽  
Epidemiologic Research ◽  
Learning Techniques ◽  
Applications Of Machine Learning

Abstract Machine learning is a branch of computer science that has the potential to transform epidemiologic sciences. Amid a growing focus on “Big Data,” it offers epidemiologists new tools to tackle problems for which classical methods are not well-suited. In order to critically evaluate the value of integrating machine learning algorithms and existing methods, however, it is essential to address language and technical barriers between the two fields that can make it difficult for epidemiologists to read and assess machine learning studies. Here, we provide an overview of the concepts and terminology used in machine learning literature, which encompasses a diverse set of tools with goals ranging from prediction to classification to clustering. We provide a brief introduction to 5 common machine learning algorithms and 4 ensemble-based approaches. We then summarize epidemiologic applications of machine learning techniques in the published literature. We recommend approaches to incorporate machine learning in epidemiologic research and discuss opportunities and challenges for integrating machine learning and existing epidemiologic research methods.

Recent Advances in the Machine Learning-Based Drug-Target Interaction Prediction

2019 ◽  
Vol 20 (3) ◽  
pp. 194-202 ◽  
Author(s):  
Wen Zhang ◽  
Weiran Lin ◽  
Ding Zhang ◽  
Siman Wang ◽  
Jingwen Shi ◽  
...  
Keyword(s):  
Machine Learning ◽  
Computational Methods ◽  
Drug Target ◽  
Prediction Models ◽  
Prediction Methods ◽  
Crucial Issue ◽  
Target Interaction ◽  
Interaction Prediction ◽  
Recent Advances ◽  
Drug Similarity

Background:The identification of drug-target interactions is a crucial issue in drug discovery. In recent years, researchers have made great efforts on the drug-target interaction predictions, and developed databases, software and computational methods.Results:In the paper, we review the recent advances in machine learning-based drug-target interaction prediction. First, we briefly introduce the datasets and data, and summarize features for drugs and targets which can be extracted from different data. Since drug-drug similarity and target-target similarity are important for many machine learning prediction models, we introduce how to calculate similarities based on data or features. Different machine learningbased drug-target interaction prediction methods can be proposed by using different features or information. Thus, we summarize, analyze and compare different machine learning-based prediction methods.Conclusion:This study provides the guide to the development of computational methods for the drug-target interaction prediction.

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