Applications of Machine Learning in Real-Time Tumor Localization
Recently, machine learning has gained great popularity in many aspects of radiation therapy. In this chapter, the authors will demonstrate the applications of various machine learning techniques in the context of real-time tumor localization in lung cancer radiotherapy. These cover a wide range of well established machine learning techniques, including principal component analysis, linear discriminant analysis, artificial neural networks, and support vector machine, etc. Respiratory gating, as a special case of tumor localization, will also be discussed. The chapter will demonstrate how domain specific knowledge and prior information can be useful in achieving more accurate and robust tumor localization. Future research directions in machine learning that can further improve the accuracy for tumor localization are also discussed.