scholarly journals Antibacterial Activity and Drug Loading of Moxifloxacin-Loaded Poly(Vinyl Alcohol)/Chitosan Electrospun Nanofibers

2021 ◽  
Vol 8 ◽  
Author(s):  
Qi Liu ◽  
Wen-Chong Ouyang ◽  
Xiu-Hong Zhou ◽  
Tao Jin ◽  
Zheng-Wei Wu
Keyword(s):  
Antibacterial Activity ◽  
Vinyl Alcohol ◽  
Composite Nanofibers ◽  
Drug Loading ◽  
Antibacterial Properties ◽  
Electrospun Nanofibers ◽  
Poly Vinyl Alcohol ◽  
X Ray Diffraction ◽  
Blank Group

In this study, nanofibers with different ratios of poly(vinyl alcohol) and chitosan incorporated with moxifloxacin hydrochloride (MH/PVA/CS) were fabricated through the blending electrospinning, and the morphological features were tested using scanning electron microscopy (SEM). Further characterization of the new nanofiber was accomplished by Thermogravimetric analysis (TG), X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FTIR). Antibacterial activity of the MH-loaded nanofibers at different drug loading were tested and compared with the blank group. Experimental results show that the MH/PVA/CS nanofibers exhibited the good antibacterial properties against Staphylococcus aureus and Pseudomonas aeruginosa due to the MH incorporation. Compared with blank nanofibers, MH/PVA/CS nanofibers have significantly better antibacterial properties, and different proportions of PVA and CS have a certain effect on the antibacterial activity of nanofibers. The conclusions in this paper show that MH/PVA/CS composite nanofibers may have great potential in antibacterial materials.

scholarly journals Fabrication and Characterization of Electrospun Wool Keratin/Poly(vinyl alcohol) Blend Nanofibers

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Shuai Li ◽  
Xu-Hong Yang
Keyword(s):  
Tensile Test ◽  
Vinyl Alcohol ◽  
Electrospun Nanofibers ◽  
Poly Vinyl Alcohol ◽  
Gravimetric Analysis ◽  
X Ray Diffraction ◽  
Sem Images ◽  
Electrospinning Method ◽  
Wool Keratin

Wool keratin/poly(vinyl alcohol) (PVA) blend nanofibers were fabricated using the electrospinning method in formic acid solutions with different weight ratios of keratin to PVA. The resultant blend nanofibers were characterized by scanning electron microscopy (SEM), Fourier transform infrared (FTIR), X-ray diffraction (XRD), thermal gravimetric analysis (TGA), and tensile test. SEM images showed that the diameter of the blend nanofibers was affected by the content of keratin in blend solution. FTIR and XRD analyses data demonstrated that there were good interactions between keratin and PVA in the blended nanofibers caused by possibly hydrogen bonds. The TGA study revealed that the thermal stability of the blend nanofibers was between those of keratin and PVA. Tensile test indicated that the addition of PVA was able to improve the mechanical properties of the electrospun nanofibers.

Electrospun poly(vinyl alcohol) nanofibrous membranes containing Coptidis Rhizoma extracts for potential biomedical applications

2018 ◽  
Vol 89 (17) ◽  
pp. 3506-3518 ◽  
Author(s):  
Jin Jeong ◽  
Seungsin Lee
Keyword(s):  
Antibacterial Activity ◽  
Vinyl Alcohol ◽  
Drug Carrier ◽  
Drug Loading ◽  
Antibacterial Properties ◽  
Wound Dressings ◽  
Poly Vinyl Alcohol ◽  
High Antibacterial Activity ◽  
Coptidis Rhizoma ◽  
Nanofibrous Membranes

Coptidis Rhizoma is a medicinal plant that is well known for its high antibacterial activity against various pathogens and its anti-inflammatory, antioxidant, and hemostatic effects. Here, nanofibrous membranes containing 10, 20, and 30 wt% of Coptidis Rhizoma extracts were fabricated by electrospinning using poly(vinyl alcohol) as the drug carrier and thermally treated to increase their aqueous stability. The antibacterial properties and release characteristics of Coptidis Rhizoma nanofibrous membranes were investigated. Coptidis Rhizoma-loaded nanocomposite fibers exhibited a high drug-loading efficiency ranging from 92% to 97%. The release profile from the nanofibrous membranes of Coptidis Rhizoma showed an initial fast release followed by a gradual release for 48 h. High antibacterial activity of the Coptidis Rhizoma-loaded nanofibrous membranes was exhibited against both Staphylococcus aureus and Staphylococcus epidermidis. These results demonstrate that poly(vinyl alcohol) nanofibrous membranes containing Coptidis Rhizoma extracts have considerable potential to be effective antimicrobial wound dressings based on natural substances.

scholarly journals Adsorption of tetracycline from water using glutaraldehyde-crosslinked electrospun nanofibers of chitosan/poly(vinyl alcohol)

2018 ◽  
Vol 77 (5) ◽  
pp. 1324-1335 ◽  
Author(s):  
Aliyeh Yousefi Abdolmaleki ◽  
Hamid Zilouei ◽  
Saied Nouri Khorasani ◽  
Kiomars Zargoosh
Keyword(s):  
Vinyl Alcohol ◽  
Electrospun Nanofibers ◽  
Poly Vinyl Alcohol ◽  
Maximum Adsorption Capacity ◽  
X Ray Diffraction ◽  
Injection Flow ◽  
Before And After ◽  
Langmuir Isotherm Model ◽  
Pseudo Second Order

Abstract In this work, the preparation and characterization of glutaraldehyde-crosslinked electrospun nanofibers of chitosan/poly(vinyl alcohol) (GCCPN) as a new adsorbent for tetracycline (TC) is reported. Electrospun nanofibers of chitosan/poly(vinyl alcohol) (PVA) were prepared by employing a 75:25 volumetric ratio of chitosan:PVA, voltage of 30 kV, collection distance of 10 cm, and injection flow rate of 2 mL/h. Then, the nanofibers were crosslinked via applying the glutaraldehyde on them for 3 h at 40 °C. The nanofibers were characterized using scanning electron microscopy, Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction. Uniform beadless nanofibers with minimum diameters of 3–11 and 6–18 nm were obtained before and after crosslinking, respectively. Then the applicability of the synthesized GCCPN for removal of TC from aqueous solutions was investigated. The response surface method was applied to evaluate the influence of pH (6–12), TC concentration (50–250 mg/L) and the adsorbent dose (0.05–0.25 g in 20 mL solution) on the adsorption characteristics of GCCPN. The maximum adsorption capacity was 102 mg/g. The adsorption kinetics was explained most effectively by the pseudo-second-order model. The adsorption data of TC on the GCCPN surface was explained well by the Langmuir isotherm model.

Preparation and characterization of gatifloxacin-loaded alginate/poly (vinyl alcohol) electrospun nanofibers

2014 ◽  
pp. 1-6 ◽  
Author(s):  
Saravanakumar Arthanari ◽  
Ganesh Mani ◽  
Jun Ho Jang ◽  
Je O Choi ◽  
Yun Ho Cho ◽  
...  
Keyword(s):  
Vinyl Alcohol ◽  
Electrospun Nanofibers ◽  
Poly Vinyl Alcohol

scholarly journals Fabrication and characterization of electrospun feather keratin/poly(vinyl alcohol) composite nanofibers

RSC Advances ◽  
2017 ◽  
Vol 7 (16) ◽  
pp. 9854-9861 ◽  
Author(s):  
Ming He ◽  
Buning Zhang ◽  
Yao Dou ◽  
Guoqiang Yin ◽  
Yingde Cui ◽  
...  
Keyword(s):  
Tensile Properties ◽  
Molecular Interactions ◽  
Vinyl Alcohol ◽  
Crystallization Behavior ◽  
Composite Nanofibers ◽  
Electrospinning Process ◽  
Poly Vinyl Alcohol ◽  
Feather Keratin ◽  
Fabrication And Characterization

We have fabricated random and aligned feather keratin (FK)/PVA composite nanofibers through an electrospinning process. The morphology, molecular interactions, crystallization behavior, and tensile properties of the nanofibers were investigated.

scholarly journals Preparation and characterization of naftifine-loaded poly(vinyl alcohol)/sodium alginate electrospun nanofibers

2020 ◽  
Vol 56 ◽  
Author(s):  
İmren Esentürk ◽  
Timuçin Balkan ◽  
Sevgi Güngör ◽  
Sezai Saraç ◽  
Meryem Sedef Erdal
Keyword(s):  
Sodium Alginate ◽  
Vinyl Alcohol ◽  
Electrospun Nanofibers ◽  
Poly Vinyl Alcohol

Preparation and Characterization of Octadecylated Poly(vinyl Alcohol) Polymers

2012 ◽  
Vol 482-484 ◽  
pp. 1921-1924 ◽  
Author(s):  
Li Juan Li ◽  
Hai Feng Shi ◽  
Xing Xiang Zhang
Keyword(s):  
Fourier Transform ◽  
Thermal Properties ◽  
Vinyl Alcohol ◽  
Phase Change Materials ◽  
Solid Phase ◽  
Poly Vinyl Alcohol ◽  
X Ray Diffraction ◽  
X Ray ◽  
Storage Properties

Octadecylated poly (vinyl alcohol) (PVA-C18) comb-like polymer was prepared through the reaction between PVA and 1-bromooctadecane via O-alkylation method. The structure, thermal properties and packing mode of PVA-C18 comb-like polymer were detailed investigated with Fourier transform infrared spectroscopy (FTIR), differential scanning calorimeter (DSC), and X-ray diffraction (XRD). The results show that octadecyl side chains had been successfully grafted onto PVA backbones, and PVA-C18 comb-like polymer exhibit the better thermal storage properties with enthalpy of 29.3kJ/mol , indicated that it is one kind of solid-solid phase change materials.

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