scholarly journals Effect of Transcutaneous Upper Eyelid Blepharoplasty on Blink Parameters and Lipid Layer Thickness

2021 ◽  
Vol 8 ◽  
Author(s):  
Siyi Zhang ◽  
Yan Yan ◽  
Yang Lu ◽  
Yixiong Zhou ◽  
Yao Fu
Keyword(s):  
Layer Thickness ◽  
Postoperative Period ◽  
Ocular Surface ◽  
Early Postoperative Period ◽  
Palpebral Fissure ◽  
Blink Rate ◽  
Lipid Layer ◽  
Ocular Surface Disease Index ◽  
Upper Eyelid ◽  
Surface Parameters

Purpose: This study aimed to investigate the effect of transcutaneous upper eyelid blepharoplasty on lipid layer thickness (LLT) and blink parameters in young women during the early postoperative period.Methods: This prospective study included 110 eyes of 55 young female patients (age range, 19–31 years) who underwent transcutaneous upper eyelid blepharoplasty. The LLT and blink parameters measured using a LipiView interferometer were recorded before the surgery and 1 week and 1 month after the surgery. Ocular Surface Disease Index (OSDI) score, noninvasive tear film breakup time (NITBUT), and palpebral fissure height (PFH) measurements were also performed at each time point.Results: The number of blinks significantly decreased (P < 0.001), and the number of partial blinks and partial blink rate (PBR) significantly increased 1 week after the surgery (P = 0.002 and P < 0.001); they all returned to baseline in 1 month. The LLT and OSDI score increased significantly 1 week and 1 month after the surgery (P < 0.001 and P < 0.001). A significant increase in the NITBUT and a significant decrease in the PFH were observed 1 week after the surgery (P < 0.001 and P < 0.001), and the values returned to baseline 1 month after the surgery. No clinical correlation was found between blink parameters and ocular surface parameters.Conclusions: Transcutaneous upper eyelid blepharoplasty led to a change in blink parameters and ocular surface parameters during the early postoperative period. However, this influence was temporary, and the transitory change in blink parameters had no effects on the ocular surface environment.

scholarly journals THE MODIFIED METHOD FOR EVISCERATION IN THE CASE OF BUPHTHALMOS WITH THE USE OF A COMBINATION OF ORBITAL IMPLANTS

2017 ◽  
Vol 12 (4) ◽  
pp. 210-215
Author(s):  
Irina Anatol’evna Filatova ◽  
I. M Mokhammad
Keyword(s):  
Postoperative Period ◽  
Early Postoperative Period ◽  
Long Term Results ◽  
Palpebral Fissure ◽  
Modified Technique ◽  
Upper Eyelid ◽  
Orbital Implants ◽  
Modified Method ◽  
Orbital Tissue ◽  
Post Traumatic

Aim. The objective of the present study was to evaluate the effectiveness of the modified technique for for evisceration in the case of buphthalmos with the use of a combination of orbital implants. Material and methods. The clinical material collected during 3 years was analyzed. The removal of the eye was performed in 385 patients of whom32 (8.1%) of the total) needed the removal because of of buphthalmos as the consequence of congenital, secondary post-traumatic glaucoma. The age of the patients ranged from 7-75 (mean 39.3 ± 5.7) years. 19 of them were males and 13 females. Nine patients presented with pronounced staphyloma of the sclera. The visual function was absent in all the cases. The modified method for evisceration included radiowave surgery with the use of a Surgitron device operated at a frequency of 3.8 Mg (Ellman, USA) and a combination of orbital implants (both intrascleral and intraconal) in order to obtain an additional volume for the stump. The Karbotextim carbon felt and polytetrafluoroethylene (PTFE) were applied as orbital implants. The surgical intervention is described in many detail. The duration of the follow-up ranged from 6 months to 3 years (mean 21 ± 6.17 months). The groups of comparison were two groups of the patients who had undergone the eye removal for buphthalmos: one of them was comprised of 14 patients treated by means of enucleation with plastic formation of the stump, the other consisted of 21 treated by traditional evisceration. Results. Wound healing in the early postoperative period occurred during normal time, without oedema and reactions to the presence of the additional implant in the orbit. Evaluation of the long-term results of the treatment was made based on the following criteria: retraction of the prosthesis and the upper eyelid into the orbit, asymmetry of the palpebral fissure, motility of the stump and the prosthesis. The best functional and cosmetic results (in comparison with enucleation and standard evisceration) were obtained in the patients treated with the use of the modified evisceration procedure and the application of the additional orbital implant. Conclusion. The modified method for evisceration in the case of buphthalmos with the use of a combination of orbital implants allows to compensate not only the volume of the eviscerated eye but also the volume of the atrophic orbital tissue. Moreover, it yields an additional stump volume of 0.5-0.7 cub. cm and permits to spare the fascial links between the orbital tissues and thereby prevent the development of stump and prosthesis hypophthalmos in the late postoperative period. The modified evisceration technique is more effective than both enucleation and standard evisceration in the patients with buphthalmos.

Ocular surface analysis: A comparison between the LipiView® II and IDRA®

2020 ◽  
pp. 112067212096903
Author(s):  
Jeong Min Lee ◽  
Young Joon Jeon ◽  
Kook Young Kim ◽  
Kyu-Yeon Hwang ◽  
Young-A Kwon ◽  
...  
Keyword(s):  
Observational Study ◽  
Layer Thickness ◽  
Surface Analysis ◽  
Ocular Surface ◽  
Random Order ◽  
Meibomian Gland ◽  
Lipid Layer ◽  
Cross Sectional ◽  
Single Visit ◽  
Significant Difference

Purpose: To compare the lipid layer thickness (LLT), meibomian gland (MG) dropouts, and blinking pattern determined by the analysis of images acquired from the LipiView® II (LVII) and the IDRA® Ocular surface analyzer. Methods: A cross-sectional single-visit observational study was conducted. The LLT (minimum, maximum, and average), percentages of MG dropouts, and partial blink rates (PBR) were taken from both eyes of 47 participants using LVII and IDRA. Both devices were used to image the inferior eyelid of each participant in a random order. Results: Forty-seven participants (mean age 56.77 ± 14.47 (21–79) years, 66% female) completed the study. There was no significant difference in LLT between the two devices. A significant difference in percentages of MG dropouts was obtained between the LVII (36.51 ± 17.53) and the IDRA (45.36 ± 21.87), p = 0.003). There was also a significant difference in PBR between the LVII (0.51 ± 0.37) and the IDRA (0.23 ± 0.27), p < 0.001). Conclusion: No significant difference in LLT was obtained between LVII and IDRA. IDRA had a significantly lesser percentage of MG dropout and a higher PBR compared to LVII. These results indicate that these devices should not be used interchangeably for the evaluation of MG dropouts and PBR.

scholarly journals A randomised, prospective study of the effects of 3% diquafosol on ocular surface following cataract surgery

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sangyoon Kim ◽  
Jonghoon Shin ◽  
Ji Eun Lee
Keyword(s):  
Multivariate Analysis ◽  
Cataract Surgery ◽  
Ocular Surface ◽  
Test Score ◽  
Surgical Techniques ◽  
Sodium Hyaluronate ◽  
Ophthalmic Solution ◽  
Disease Index ◽  
Lipid Layer ◽  
Ocular Surface Disease Index

AbstractThere is still no established therapeutic solution for postoperative Dry Eye Syndrome (DES) after cataract surgery, in spite of progress in surgical techniques. Diquafosol tetrasodium (DQS), a recently developed ophthalmic solution, has been reported to be effective in DES, but no study evaluated post-cataract surgery lipid layer thickness (LLT) changes in healthy patients who used DQS postoperatively. We randomly divided participants into two groups; the DQS group was treated six times daily with DQS after cataract surgery, and the sodium hyaluronate (HA) group was treated with HA in the same way. Throughout study period, the DQS group showed significantly higher tear break up time (TBUT) and LLT than HA group. In multivariate analysis, better preoperative TBUT, Schirmer’s I test score, ocular surface disease index (OSDI) score, and LLT were significantly associated with improved postoperative outcomes in each parameter. Also, the postoperative use of DQS served as an independent parameter of better TBUT, OSDI score, and LLT in postoperative 15 weeks. Treatment with 3% DQS following cataract surgery showed more improvement in TBUT and LLT, compared with 0.1% HA. Improving TBUT and LLT preoperatively and using 3% DQS postoperatively, could be a reliable choice for managing DES after cataract surgery.Trial Registration: ISRCTN registry with ISRCTN 18755487.

scholarly journals Impact of pterygium on the ocular surface and meibomian glands

2019 ◽  
Author(s):  
Ana Cláudia Viana Wanzeler ◽  
Italo Antunes França Barbosa ◽  
Bruna Duarte ◽  
Eduardo Buzolin Barbosa ◽  
Daniel Almeida Borges ◽  
...  
Keyword(s):  
Ocular Surface ◽  
Tear Film ◽  
Lower Eyelid ◽  
Meibomian Gland ◽  
Conjunctival Hyperemia ◽  
Upper Eyelid ◽  
Film Stability ◽  
Surface Parameters ◽  
Meibomian Glands ◽  
The Impact

AbstractPurposeTo analyze how ocular surface parameters correlate to pterygium and investigate the possible impact on tear film and meibomian glands.Methodswe investigated objective parameters of the ocular surface such as conjunctival hyperemia, tear film stability and volume, meibomian gland dysfunction, dry eye disease, corneal topography comparing healthy individuals and correlating with the pterygium clinical presentation.ResultsA total of 83 patients were included. Corneal astigmatism induction was 2.65 ± 2.52 D (0.4-11.8). The impact of pterygium on the ocular surface parameters compared to matched controls was seen in: conjunctival hyperemia (control 1.55±0.39/pterygium 2.14±0.69; p=0.0001), tear meniscus height (control 0.24±0.05 mm/pterygium 0.36±0.14mm; p 0.0002), meiboscore lower eyelid (control 0.29±0.64/pterygium 1.38±0.95; p 0.0001) and meiboscore upper eyelid (control 0.53±0.62/pterygium 0.98±0.75; p=0.0083). We found a high number of pterygium patients (88%) presented meibomian gland alterations. Interestingly, meibomian gland loss was coincident to the localization of the pterygium in 54% of the upper and 77% lower lids.ConclusionPterygium greatly impacts on ocular surface by inducing direct alterations in the pattern of meibomian glands besides corneal irregularities, conjunctival hyperemia and lacrimal film alterations, inducing significant symptoms and potential signs of dysfunction.

scholarly journals Comparison of BAK-preserved Latanoprost and Polyquad-preserved Travoprost on Ocular Surface Parameters in Patients with Glaucoma and Ocular Hypertension

2021 ◽  
Author(s):  
Omer Ersin Muz ◽  
Kenan Dagdelen ◽  
Tuncay Pirdal ◽  
Mete Guler
Keyword(s):  
Ocular Hypertension ◽  
Ocular Surface ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Corneal Thickness ◽  
Schirmer Test ◽  
Ocular Surface Disease Index ◽  
Surface Parameters ◽  
Surface Staining

Abstract Background To compare the effect of two different prostaglandin analogues (Travatan® vs. Xalatan®) on ocular surface parameters. Methods This study includes 44 eyes of 44 patients with newly diagnosed primary open-angle glaucoma (POAG) or ocular hypertension (OHT). Patients were randomly divided into two groups and treated with either benzalkonium chloride (BAK)-preserved latanoprost and polyquad-preserved travoprost. Changes in intraocular pressure (IOP) levels and ocular surface parameters including ocular surface disease index (OSDI) questionnaire, tear break-up time (TBUT), ocular surface staining scores, and Schirmer test scores of patients were performed at baseline, 1, 3, 6 and 12 months of treatment and compared. Results The age, sex ratio, visual acuity, central corneal thickness, and cup/disc ratio were similar between the groups. A decrease in IOP levels (23.3 ± 2.5 to 15.5 ± 2.3), TBUT (5.5 ± 2.3 to 4.1 ± 1.7 sec), Schirmer test values (11.3 ± 5.9 to 8.6 ± 4.7 sec), and a worsening in OSDI scores (44.6 ± 15.2 to 55.1 ± 13.1) and staining scores (1.7 ± 1.6 to 2.3 ± 1.8) were observed in all patients in the first month of treatment (p < 0.05, for all). No further worsening was detected during the 1-year follow-up. There was no difference between the groups in terms of alterations in IOP levels and ocular surface parameters. Conclusion Travatan® and Xalatan® have a similar effect on IOP levels and ocular surface parameters in patients with POAG and OHT.

scholarly journals Tear Film Osmolarity of the Eye after Cataract Surgery. Summary of the Doctoral Thesis

2021 ◽  
Author(s):  
◽  
Ēriks Elksnis ◽  
Keyword(s):  
Cataract Surgery ◽  
Postoperative Period ◽  
Ocular Surface ◽  
Tear Film ◽  
Visual Outcome ◽  
Early Postoperative Period ◽  
University Hospital ◽  
Control Group ◽  
Study Group ◽  
Significant Difference

Almost every cataract surgeon has encountered a situation during the postoperative period when, even though, the primary goal – improvement of visual acuity – has been achieved, yet the patient felt frustrated because of subjective discomfort in the operated eye. Sometimes this issue is more disturbing for the patient than the hope for a perfect visual outcome. Although it has been established that the ocular surface is affected during the postoperative period, there is still no generally accepted opinion about the changes in tear osmolarity after cataract surgery despite several studies dedicated to evaluation of these changes. The present study was designed to elucidate the effect of cataract surgery on the characteristic feature of ocular surface homeostasis – tear film osmolarity in the early postoperative period. Aim. The aim of the study was to evaluate the changes in tear film osmolarity after a cataract surgery in a healthy ocular surface. Methods. For this purpose two examination groups were formed. The study group included voluntary patients undergoing cataract surgery not having any complaints about subjective symptoms typical of dry eye disease. In order to correspond to the criteria of healthy ocular surface, the study group excludes the following types of patients and conditions: contact lens wearers, patients with diabetes, pseudoexfoliation, pterygia and eye drop users. The eye that has not undergone the surgery was classified as the control group. This single–center, prospective study was held at Ophthalmology department of Pauls Stradins Clinical university hospital. All cataract surgeries were done by the same surgeon. The tear osmolarity tests were evaluated with TearLab Osmolarity System (TearLab Corporation, San Diego, CA, the USA) before surgery, in the next morning, one week and one month after the surgery. Results. No statistically significant difference was observed between the groups before operation when comparing the mean tear osmolarity – in the study group it was 296.87 mOsm/L, and in the control group it was 297.27 mOsm/L (p = 0.84). The tear osmolarity results changed significantly during early postoperative period in the study group (p < 0.001), while in non–operated eye no significant tear film osmolarity changes were observed (p = 0.86). Significant changes were recognized on the next day after the surgery – the tears became hypoosmolar (< 275 mOsm/L). One week later the tear osmolarity increased significantly, and the tears became hyperosmolar (312.64 mOsm/L). Over the course of one month, the test values for the study and control groups equalized (297.87 in the study group and 298.93 in the control group (p = 0.66)), when compared to preoperative tear osmolarity results. Conclusion. The results achieved lead towards a more detailed understanding of the changes in the ocular surface homeostasis after a cataract surgery. The obtained data indicate that tear osmolarity changes considerably during the first postoperative month after a cataract surgery. Also, there is a huge difference in measurements between operated and non–operated eye on the next day and one week after the surgery. One month after the surgery tear osmolarity returns to preoperative test results, and there is no difference determined between the eyes.

scholarly journals Characteristics of dry eye patients with thick tear film lipid layers evaluated by a LipiView II interferometer

2021 ◽  
Author(s):  
Yunjin Lee ◽  
Joon Young Hyon ◽  
Hyun Sun Jeon
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Tear Film ◽  
Sensitivity Analyses ◽  
Lipid Layer ◽  
Ocular Surface Disease Index ◽  
Surface Staining ◽  
Physiologic Condition ◽  
Cautious Interpretation ◽  
Lipid Layers

Abstract Purpose To investigate the characteristics of eyes with dry eye disease (DED) whose lipid layer thickness (LLT) measured 100 nm on a LipiView II interferometer and compare the DED parameters of them to those with LLT below 100 nm. Methods A total of 201 eyes of 102 enrolled DED patients (mean age 56.4 ± 11.8 years) were classified into 3 groups according to their average LLT; < 60 nm as thin-LLT (n = 49), 60–99 nm as normal-LLT (n = 77), and 100 nm as thick-LLT (n = 75). LLT, meiboscore, Schirmer I test, tear film break-up time (TBUT), ocular surface staining (OSS), and ocular surface disease index (OSDI) were assessed. Results The OSS and TBUT were significantly worse in the thick-LLT group than in the normal-LLT group (p = 0.020, and p = 0.028, respectively). The OSDI was significantly higher in the thick-LLT group than in the thin-LLT group (p = 0.006). However, the meiboscore was not different among the three groups (p = 0.33). Age, OSS, and OSDI showed a positive correlation with LLT (r = 0.16, p = 0.023; r = 0.213, p = 0.003; and r = 0.338, p = 0.001, respectively). In sensitivity analyses, eyes with corneal erosions had a significantly higher average LLT (p = 0.015), higher OSDI (p = 0.009), shorter TBUT (p < 0.001), and shorter Schirmer I value (p = 0.024) than those with clear corneas. Conclusion The average LLT of eyes with corneal erosions was thicker than those without erosions, suggesting that the LLT of 100 nm in the eyes with corneal erosions should not be regarded as a stable physiologic condition. Cautious interpretation of LLT along with other dry eye parameters is required.

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