scholarly journals Cytochrome P450 Sterol 14 Alpha-Demethylase Gene SsCI72380 Is Required for Mating/Filamentation and Pathogenicity in Sporisorium scitamineum

2021 ◽  
Vol 12 ◽  
Author(s):  
Huizhong Li ◽  
Yichang Cai ◽  
Quanqing Deng ◽  
Han Bao ◽  
Jianwen Chen ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Cell Membrane ◽  
Sugar Industry ◽  
Control Strategies ◽  
Wall Stress ◽  
Effective Prevention ◽  
Sporisorium Scitamineum ◽  
Stress Oxidative ◽  
And Function ◽  
And Control

Sugarcane smut is a significant sugarcane disease caused by Sporisorium scitamineum and is a large threat to the sugar industry in China and the world. Accordingly, it is important to study the pathogenic mechanism by which this disease occurs to identify effective prevention and control strategies. Gene SsCI72380, which encodes cytochrome P450 sterol 14 alpha-demethylase (CYP51), was screened out from the transcriptome of S. scitamineum. In this study, the functions of gene SsCI72380 were identified via the knockout mutants ΔSs72380+ and ΔSs72380−, which were obtained by polyethylene glycol (PEG)-mediated protoplast transformation technology, as well as the complementary mutants COM72380+ and COM72380−. The results showed that the CYP51 gene SsCI72380 played an important role in sporidial growth, sexual mating/filamentation, hyphae growth, and pathogenicity in S. scitamineum. Gene SsCI72380 may regulate the biosynthesis process of ergosterol by encoding CYP51 enzymes and then affecting the structure and function of the cell membrane. Gene SsCI72380 also played an important role in the response toward different abiotic stresses, including hyperosmotic stress, oxidative stress, and cell wall stress, by regulating the permeability of the cell membrane. In addition, gene SsCI72380 is a new type of pathogenic gene from S. scitamineum that enhances the pathogenicity of S. scitamineum.

scholarly journals Trends of HIV/AIDS Highlighted the Progresses and Challenges in Prevention and Control From 1990 to 2019

2021 ◽  
Author(s):  
Zejin Ou ◽  
Huan He ◽  
Danfeng Yu ◽  
Yongzhi Li ◽  
Yuanhao Liang ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Control Strategies ◽  
Health Concern ◽  
Effective Prevention ◽  
Global Trends ◽  
Life Years ◽  
Disease Study ◽  
And Control ◽  
Increasing Trends ◽  
Hiv Aids

Abstract Background HIV/AIDS is a critical public health concern worldwide. This article aimed to demonstrate th trends of HIV/AIDS burden from 1990 to 2019.Methods Data was extracted from the Global Burden of Disease study (GBDs) 2019. Estimated annual percentage change (EAPC) and age-standardized rate (ASR) were estimated to quantify the trends at global, regional and national levels.Results During the period 1990-2004, the trend in incidence of HIV/AIDS was stable globally. Whereas the trends in prevalence, death and disability-adjusted life years (DALYs) had pronounced increasing trends, with the respective EAPCs were 7.47 (95%confidence interval [CI]: 5.84 to 9.12), 10.85(95%CI: 8.90 to 12.84), and 10.40(95%CI: 8.47 to 12.36). Meanwhile, the pronounced increasing trends were seen in low-resource settings, particularly that of death in Oceania and South Asia, in which the respective EAPCs were 44.76 (95%CI: 40.81 to 48.82) and 40.82 (95%CI: 34.31 to 47.64). However, the global trends in incidence, death and DALYs of HIV/AIDS pronouncedly decreased from 2005 to 2019, with the respective EAPCs were −2.68(95%CI: −2.82 to −2.53), −6.73(95%CI: −6.98 to −6.47) and −6.75(95%CI: −6.95 to −6.54). Whereas prevalence showed increasing trend (EAPC: 0.71, 95%CI: 0.54 to 0.87). Decreasing trends of HIV/AIDS were observed in most regions and countries, particularly that of death and DALYs in Burundi respectively were −15.28 (95%CI: −16.08 to −14.47) and −15.07 (95%CI: −15.79 to −14.33). Conclusions Decreasing trends of HIV/AIDS were observed worldwide over the past 15 years. However, HIV/AIDS remains one of the most critical causes of health loss worldwide, which emphasized the effective prevention and control strategies.

scholarly journals Prevention and Control Strategy of Reader Factors in Safety Management of Electronic Reading Room

2021 ◽  
Vol 5 (5) ◽  
pp. 20-24
Author(s):  
Yanping Dong
Keyword(s):  
Control Strategy ◽  
Prevention And Control ◽  
Safety Management ◽  
Control Strategies ◽  
Reading Room ◽  
Effective Prevention ◽  
Management Level ◽  
Electronic Reading ◽  
Specific Safety ◽  
And Control

Many libraries have built and opened the electronic reading room, electronic reading room security management has been paid more and more attention. In the specific safety management, the prevention and control of reader factors is very important. By comparing and analyzing the prevention and control of reader factors in the safety management of some electronic reading rooms, it can be found that the corresponding prevention and control situation is not ideal, and even there are some obvious problems, which also leads to great hidden dangers in the safety management level. This paper will specifically analyze the prevention and control of reader factors in the safety management of electronic reading room, and put forward more effective prevention and control strategies.

scholarly journals Experience in Prevention and Control Work of Anti-COVID-19 in People's Hospital of Tongchuan City in China

2020 ◽  
pp. 22-25
Author(s):  
Hu Guizhong ◽  
Liu Wanqing ◽  
Wang Jianhua ◽  
Guo Chunli ◽  
. Xiaoli ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Control Strategies ◽  
Effective Prevention ◽  
The North ◽  
Comprehensive Level ◽  
Missed Diagnosis ◽  
Control Work ◽  
Prevention Of Nosocomial Infection ◽  
And Control ◽  
Acid Test

Objective: To explore the prevention and control strategies and effects of COVID-19 in People's Hospital of Tongchuan so as to provide evidence for prevention and control of COVID-19 in Tongchuan. Methods: The measures taken by People's Hospital of Tongchuan from the aspects of sound organization, new coronavirus knowledge training, prevention of nosocomial infection, establishment of elite medical team, scientific and precise treatment and internet application as well as medical treatment were reviewed. Results: Between 23 January 2020 and 15 April 2020, the hospital had received a total of 6 patients with confirmed COVID-19, among which 3 patients have been discharged. More than 31,000 persons were given pre-examination triage, 2,605 persons were treated for fever at clinics, 596 persons were under isolation and observation, and 184 persons had nucleic acid test, so as to achieve the requirements of no missed diagnosis, no death and no infection goal, which were prioritized by the national, provincial and municipal health inspection teams. Conclusion: The effective prevention and control strategies against COVID-19 in People’s Hospital of Tongchuan have significantly achieved the "three zeros" goal namely zero infection, zero transmission and zero death. People's Hospital of Tongchuan, founded in 1949, is a comprehensive level-III first-class hospital. It has two hospitals located in the north and the south, with 1,700 beds and 2,044 employees. It is the first designated hospital for treatment of COVID-19 [1] in the province.

A brief review of foodborne zoonoses in China

2011 ◽  
Vol 139 (10) ◽  
pp. 1497-1504 ◽  
Author(s):  
D. SHAO ◽  
Z. SHI ◽  
J. WEI ◽  
Z. MA
Keyword(s):  
Public Health ◽  
Food Consumption ◽  
Food Production ◽  
Prevention And Control ◽  
Control Strategies ◽  
Paper Briefly ◽  
Effective Prevention ◽  
Socioeconomic Changes ◽  
International Attention ◽  
And Control

SUMMARYFoodborne zoonoses have a major impact on public health in China. Its booming economy and rapid socioeconomic changes have affected food production, food supplies and food consumption habits, resulting in an increase in the number of outbreaks of foodborne zoonoses. Both emerging and re-emerging foodborne zoonoses have attracted increasing national and international attention in recent years. This paper briefly reviews the main foodborne zoonoses that have had a major impact on public health over the last 20 years in China. The major causative microorganisms, including foodborne bacteria, parasites and viruses, are discussed. The prevention and control of foodborne zoonoses are difficult challenges in China. The information provided here may aid the development of effective prevention and control strategies for foodborne zoonoses.

scholarly journals Molecular Epidemiology and Genetic Diversity of Zika Virus from Field-Caught Mosquitoes in Various Regions of Thailand

Pathogens ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. 30 ◽  
Author(s):  
Atchara Phumee ◽  
Rome Buathong ◽  
Rungfar Boonserm ◽  
Proawpilart Intayot ◽  
Nucharat Aungsananta ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Molecular Epidemiology ◽  
Zika Virus ◽  
Control Strategies ◽  
Mosquito Species ◽  
Structural Protein ◽  
Effective Prevention ◽  
Armigeres Subalbatus ◽  
Geographic Regions ◽  
And Control

Zika virus (ZIKV) infection is an emerging and re-emerging arbovirus disease that is transmitted to humans through the bite of infected mosquitoes. ZIKV infections were first described in Thailand in 1954 from the sera of indigenous residents and several travelers returning from Thailand in 2014. However, reported cases in Thailand have been increasing since 2015 and 2016, and epidemiological information about the vectors of ZIKV is unclear. We investigated the molecular epidemiology and genetic diversity of ZIKV from mosquitoes collected from different geographic regions experiencing ZIKV outbreaks in Thailand. Polymerase chain reaction was used to amplify the non-structural protein (NS5) gene of ZIKV, which was then sequenced. A total of 1026 mosquito samples (626 females, 367 males, and 33 larvae) were collected from active ZIKV patients’ houses. ZIKV was detected in 79 samples (7.7%), including Aedes aegypti (2.24% female, 1.27% male, and 0.19% larvae), Culex quinquefasciatus (1.85% female, 1.66% male, and 0.29% larvae), and Armigeres subalbatus (0.1% female and 0.1% male), whereas no ZIKV was detected in Aedes albopictus. Phylogenetic analysis of the 79 positive samples were classified into two clades: Those closely related to a previous report in Thailand, and those related to ZIKV found in the Americas. This is the first report of the detection of ZIKV in Ae. aegypti, Cx. quinquefasciatus, and Ar. subalbatus mosquitoes, and genetic variations of ZIKV in the mosquitoes collected from several geographic regions of Thailand were examined. Detection of ZIKV in male and larval mosquitoes suggests that vertical transmission of ZIKV occurred in these mosquito species. This study provides a more in-depth understanding of the patterns and epidemiologic data of ZIKV in Thailand; the data could be used for future development of more effective prevention and control strategies of ZIKV in Thailand.

scholarly journals Maintenance of Fish Health in Aquaculture: Review of Epidemiological Approaches for Prevention and Control of Infectious Disease of Fish

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Ayalew Assefa ◽  
Fufa Abunna
Keyword(s):  
Infectious Disease ◽  
Traffic Control ◽  
Prevention And Control ◽  
Control Strategies ◽  
Disease Outbreaks ◽  
Effective Prevention ◽  
Disease Case ◽  
And Control ◽  
Water Treatments ◽  
The Impact

Aquaculture is rapidly growing part of agriculture worldwide. It makes up around 44 percent of total fish production globally. This increased growth of production is achieved despite facing many challenges in the aquaculture environment. Among production limiting challenges, the infectious disease takes the lion share by causing multibillion-dollar loss annually. To reduce the impact of the fish disease, it is necessary to address health constraints based on scientifically proven and recommended ways. This review aims at pointing out some of the best approaches to prevention and control of infectious disease in aquaculture. Among the effective prevention and control strategies, vaccination is one of the key practices. Types of vaccines for use in fish include killed vaccines, attenuated vaccines, DNA vaccines, recombinant technology vaccines, and synthetic peptide vaccines. Administration techniques of vaccines in fish include oral, injection, or immersion methods. Antibiotics are also in use in aquaculture despite their side effects in the development of drug resistance by microorganisms. Biological and chemical disease control strategies such as using probiotics, prebiotics, and medicinal plants are widely in use. Biosecurity measures in aquaculture can keep the safety of a facility from certain disease-causing agents that are absent in particular system. Farm-level biosecurity measures include strict quarantine measures, egg disinfection, traffic control, water treatments, clean feed, and disposal of mortalities. In conclusion, rather than trying to treat every disease case, it advisable to follow a preventive approach before the event of any disease outbreaks.

scholarly journals Prevention and Control Measures and Effects of COVID-19 in Shenmu City Hospital, China

2020 ◽  
pp. 18-24
Author(s):  
Gao Kun ◽  
Liu Hong ◽  
Liu Yonglin ◽  
Wang Qiang ◽  
Qiao Zhenliang ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Control Strategies ◽  
Control Program ◽  
High Risk Group ◽  
Control Measures ◽  
City Hospital ◽  
Effective Prevention ◽  
Management Procedures ◽  
Prevention And Control Measures ◽  
And Control

Purpose: To explore the prevention and control strategies and effects of COVID-19 in Shenmu City Hospital, so as to provide basis for the prevention and control of COVID-19 in Shenmu City. Methods: Retrospective analysis and review of our hospital after the outbreak of COVID-19 prevention and control program, response measures and management procedures and other aspects of the deployment. Results: In the 86 days up to April 15, 2020, there were 7,843 pre-diagnosis and triage patients, among which 707 were high-risk group, 3,140 were general population and 3,996 were key population. 992 patients were treated in COVID-19 clinics, 2 suspected cases were reported and 89 were kept under observation. 5, 351 visits in general fever clinics; 89 cases were hospitalized in isolation ward, including 2 suspected cases. COVID-19 was discharged after improvement. Conclusion: Initial progress has been made in epidemic prevention and control. COVID-19 has not been reported in the whole city. It shows that effective prevention and control strategies are of great significance for achieving the goal of "three zeros" (zero infection, zero spread and zero death), and are worth learning and promoting.

Effective infection prevention and control strategies in a large accredited psychiatric facility in Singapore

2020 ◽  
Author(s):  
Daniel Poremski ◽  
Sandra Henrietta Subner ◽  
Grace Lam Fong Kin ◽  
Raveen Dev Ram Dev ◽  
Mok Yee Ming ◽  
...  
Keyword(s):  
Mental Health ◽  
Prevention And Control ◽  
Infection Prevention ◽  
Control Strategies ◽  
Infection Prevention And Control ◽  
Psychiatric Facility ◽  
Essential Services ◽  
Community Transmission ◽  
And Control

The Institute of Mental Health in Singapore continues to attempt to prevent the introduction of COVID-19, despite community transmission. Essential services are maintained and quarantine measures are currently unnecessary. To help similar organizations, strategies are listed along three themes: sustaining essential services, preventing infection, and managing human and consumable resources.

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