Post-stroke Depression Increases Disability More Than 15% in Ischemic Stroke Survivors: A Case-Control Study

Background: The dysphagia screening in acute ischemic stroke plays an important role in patients with risk of dysphagia. The aim of this hospital-based case-control study is to explore if V-VST, as a new nurse-driven dysphagia screening tool for AIS patients, might help to reduce the rate of post-stroke pneumonia and early withdraw of feeding tube. Methods: 1598 acute ischemic stroke patients were enrolled in this study. The standard protocol in AIS patients were assessed by WST (before intervention and plus with V-VST after intervention). The V-VST assessment were be trained in two senior nurses and all AIS patients were assessed by V-VST during July 1and Dec 30 th , 2017. Among 299 AIS patients with suspected, all clinical data were analyzed. The comparison of their rate of pneumonia in hospital and withdraw rate of tubefeeding before discharge were performed between patients post-intervention (January 1, 2018-June 30, 2019)and those admitted before the intervention (January 1, 2016-June 30, 2017). Results: The baseline characteristics of the pre- and post- intervention AIS groups were similar in age, gender, NIHSS. The implementation of V-VST have a statistically significant reducing the risk of pneumonia with an adjusted HR (0.60, 95% CI 0.43-0.84, P=0.003). Additionally, follow-up V-VST were likely to be associated the withdraw rate of tube-feeding at discharge (29/168 vs 38/131 P=0.016).There is also a trend of length of tube-feeding decreasing (8.32±12.27 vs 6.84±8.61 P=0.241). Conclusion: In our study, the V-VST is a feasible bedside tool. The implemental might be associated with the reduction of post-stroke pneumonia. Therefore, it meets the requirements of a clinical screening test for dysphagia in acute stroke patients at bedside. Large prospective interventional study is needed to confirm our findings. V-VST: Volume-viscosity Swallow Test WST: Water Swallow Test AIS: Acute Ischemic Stroke HR: hazard ratio

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Rehabilitative ultrasound imaging of the bilateral intrinsic plantar muscles and fascia in post-stroke survivors with hemiparesis: A case-control study.

International Journal of Medical Sciences ◽

10.7150/ijms.25836 ◽

2018 ◽

Vol 15 (9) ◽

pp. 907-914 ◽

Cited By ~ 6

Author(s):

Cesar Calvo-Lobo ◽

Ana Isabel Useros-Olmo ◽

Jaime Almazán-Polo ◽

Ricardo Becerro-de-Bengoa-Vallejo ◽

Marta Elena Losa-Iglesias ◽

...

Keyword(s):

Ultrasound Imaging ◽

Case Control Study ◽

Case Control ◽

Stroke Survivors ◽

Post Stroke ◽

Control Study

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White matter hyperintensities in post-stroke depression: a case control study

Journal of Neurology Neurosurgery & Psychiatry ◽

10.1136/jnnp.2009.203141 ◽

2010 ◽

Vol 81 (12) ◽

pp. 1312-1315 ◽

Cited By ~ 23

Author(s):

W. K. Tang ◽

Y. K. Chen ◽

J. Y. Lu ◽

W. C. W. Chu ◽

V. C. T. Mok ◽

...

Keyword(s):

White Matter ◽

White Matter Hyperintensities ◽

Case Control Study ◽

Case Control ◽

Post Stroke ◽

Post Stroke Depression ◽

Control Study

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Individual and Combined Associations of Fasting Serum Lipids with Incident Risk of First Ischemic Stroke: A Chinese Community-Based Nested Case-Control Study

SSRN Electronic Journal ◽

10.2139/ssrn.3569876 ◽

2020 ◽

Author(s):

Yue Zhang ◽

Jingyi Li ◽

Chengzhang Liu ◽

Hongxiang Yu ◽

Chen Chen ◽

...

Keyword(s):

Ischemic Stroke ◽

Serum Lipids ◽

Case Control Study ◽

Case Control ◽

Chinese Community ◽

Fasting Serum ◽

Community Based ◽

Nested Case Control ◽

Control Study

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Correlation between matrix metalloproteinase-2 polymorphisms and first and recurrent atherosclerotic ischemic stroke events: a case–control study

Journal of International Medical Research ◽

10.1177/03000605211022967 ◽

2021 ◽

Vol 49 (6) ◽

pp. 030006052110229

Author(s):

Ying Li ◽

Qing-rong Ouyang ◽

Juan Li ◽

Xiao-rong Chen ◽

Lin-lin Li ◽

...

Keyword(s):

Ischemic Stroke ◽

Matrix Metalloproteinase ◽

Chinese Population ◽

Case Control Study ◽

Case Control ◽

Matrix Metalloproteinase 2 ◽

Odds Ratios ◽

Control Study

Objective To determine the associations between matrix metalloproteinase-2 (MMP-2, encoded by the MMP2 gene) 1306C/T and 735C/T polymorphisms and first and recurrent ischemic stroke in a Chinese population. Methods Patients with first and recurrent ischemic stroke were included. Serum MMP-2 was measured, and MMP2 1306C/T and 735C/T polymorphisms were detected. The associations between MMP2 1306C/T and 735C/T polymorphisms and first and recurrent ischemic stroke were analyzed. Results Serum MMP-2 in patients with first and recurrent ischemic stroke was significantly higher compared with controls, and patients with recurrent ischemic stroke had higher MMP-2 than those with first ischemic stroke. The frequency of the CC genotype and C allele of MMP2 735C/T was highest in patients with recurrent ischemic stroke, followed by patients with first ischemic stroke, and controls. Conversely, the genotype and allele of MMP2 1306C/T did not significantly differ between groups. The CC genotype of MMP2 735C/T was independently associated with first and recurrent ischemic stroke (odds ratios = 1.45 and 1.64, respectively), as was the C allele of MMP2 735C/T (odds ratios = 1.68 and 1.77, respectively). Conclusions The CC genotype and C allele of MMP2 735C/T were associated with first and recurrent ischemic stroke in a Chinese population.

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