scholarly journals Individualized Responses to Ipsilesional High-Frequency and Contralesional Low-Frequency rTMS in Chronic Stroke: A Pilot Study to Support the Individualization of Neuromodulation for Rehabilitation

2020 ◽  
Vol 14 ◽  
Author(s):  
John Harvey Kindred ◽  
Elizabeth Carr Wonsetler ◽  
Charalambos Costas Charalambous ◽  
Shraddha Srivastava ◽  
Barbara Khalibinzwa Marebwa ◽  
...  
Keyword(s):  
Pilot Study ◽  
High Frequency ◽  
Low Frequency ◽  
Chronic Stroke ◽  
Low Frequency Rtms

Neurocognitive Effects of Repetitive Transcranial Magnetic Stimulation in Patients with Cerebrovascular Disease Without Dementia

2008 ◽  
Vol 22 (1) ◽  
pp. 14-19 ◽  
Author(s):  
S. Sedlackova ◽  
I. Rektorova ◽  
Z. Fanfrdlova ◽  
I. Rektor
Keyword(s):  
Pilot Study ◽  
High Frequency ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Low Frequency ◽  
Specific Effect ◽  
Frameless Stereotaxy ◽  
Stimulation Site ◽  
Positive Effects ◽  
Vascular Type ◽  
Low Frequency Rtms

Aims: The results of our pilot study suggested that one session of high frequency rTMS applied over the left dorsolateral prefrontal cortex (DLPFC) might induce measurable positive effects on executive functioning in patients with mild cognitive impairment of the vascular type without dementia (MCI-V). The aims of the current study were to replicate the results of our pilot study using a frameless stereotaxy as opposed to the standard and routinely used procedure. We also studied the effects of low frequency rTMS. Patients and method: Seven patients with MCI-V participated in a randomized, controlled, blind study with a crossover design. Each patient received 10 Hz and 1 Hz stimulation over the left DLPFC (an active stimulation site) or the motor cortex (MC; a control stimulation site). Frameless stereotaxy was used to target the DLPFC. The order of sites and frequencies was randomized. A short battery of neuropsychological tests was performed to evaluate executive function, working memory, and psychomotor speed. Results: One session of both high and low frequency rTMS was well tolerated and safe in terms of the cognitive after-effects in patients with MCI-V. We did not observe any significant frequency dependent or stimulation site-dependent cognitive effects of rTMS. Conclusion: We found neither positive nor negative significant effect of either low or high frequency rTMS applied over the DLPFC or the MC, while a mild positive site-specific effect of 10 Hz rTMS was observed in our pilot study on the Stroop interference results. These results suggested that MCI-V is a heterogeneous and poorly defined entity and, thus, rTMS might be useful in a subpopulation of this group of patients.

High-frequency priming stimulation does not enhance the effect of low-frequency rTMS in the treatment of tinnitus

2007 ◽  
Vol 184 (4) ◽  
pp. 587-591 ◽  
Author(s):  
Berthold Langguth ◽  
Tobias Kleinjung ◽  
Elmar Frank ◽  
Michael Landgrebe ◽  
Philipp Sand ◽  
...  
Keyword(s):  
High Frequency ◽  
Low Frequency ◽  
Low Frequency Rtms

Optimal frequency of whole body vibration training for improving balance and physical performance in the older people with chronic stroke: A randomized controlled trial

2021 ◽  
pp. 026921552110505
Author(s):  
Ning Wei ◽  
Mengying Cai
Keyword(s):  
Older People ◽  
Physical Performance ◽  
High Frequency ◽  
Low Frequency ◽  
Chronic Stroke ◽  
Whole Body ◽  
Timed Up And Go ◽  
Stand Test ◽  
Sit To Stand ◽  
Frequency Group

Objective To explore the optimal frequency of whole-body vibration training for improving the balance and physical performance in older people with chronic stroke. Design a single-blind randomized controlled trial. Setting Two rehabilitation units in the Wuhan Brain Hospital in China. Participants A total of 78 seniors with chronic stroke. Interventions Low-frequency group (13 Hz), high-frequency group (26 Hz), and zero-frequency group (Standing on the vibration platform with 0 Hz) for 10 sessions of side-alternating WBV training. Main measures The timed-up-and-go test, five-repetition sit-to-stand test, 10-metre walking test, and Berg balance scale were assessed pre- and post-intervention. Results Significant time × group interaction effects in five-repetition sit-to-stand test (p = 0.014) and timed-up-and-go test at self-preferred speed (p = 0.028) were observed. The high-frequency group outperformed the zero-frequency group in both five-repetition sit-to-stand test (p = 0.039) and timed-up-and-go test at self-preferred speed (p = 0.024) after 10-sessions training. The low-frequency group displayed only a significant improvement in five-repetition sit-to-stand test after training (p = 0.028). No significant within- or between-group changes were observed in the Berg balance scale and walking speed (p > 0.05). No significant group-difference were found between low-frequency and high-frequency groups. No adverse events were reported during study. Conclusions Compared with 13 Hz, 26 Hz had no more benefits on balance and physical performance in older people with chronic stroke.

Low-frequency rTMS is better tolerated than high-frequency rTMS in healthy people: Empirical evidence from a single session study

2019 ◽  
Vol 113 ◽  
pp. 79-82 ◽  
Author(s):  
Manreena Kaur ◽  
Jessica A. Michael ◽  
Bernadette M. Fitzgibbon ◽  
Kate E. Hoy ◽  
Paul B. Fitzgerald
Keyword(s):  
Empirical Evidence ◽  
High Frequency ◽  
Low Frequency ◽  
Healthy People ◽  
Single Session ◽  
Low Frequency Rtms

The effects of different frequencies of repetitive transcranial magnetic stimulation (rTMS) on intracranial neurotransmitters in patients with swallowing disorders after cerebral infarction

2019 ◽  
Author(s):  
Yupeng Du ◽  
Li Wei ◽  
Huangwei Jiang
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Cerebral Infarction ◽  
Test Scores ◽  
High Frequency ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Low Frequency ◽  
Swallowing Disorders ◽  
Control Group ◽  
Low Frequency Rtms

Abstract Objective To study the improvements and mechanism of repetitive transcranial magnetic stimulation (rTMS) on swallowing disorders after cerebral infarction. Methods A total of 60 patients with swallowing disorders were randomly assigned to receive high/low-frequency rTMS treatment, another 30 patients without rTMS treatment were included in the control group. The Kubota’s water-swallowing test, video fluoroscopic swallowing study (VFSS), and major intracranial neurotransmitters were analyzed before and after treatment. Results No significant difference was observed in the Kubota’s water-swallowing test scores, the VFSS scores, or the levels of intracranial neurotransmitters between the three groups before treatment. The Kubota’s water-swallowing test scores were significantly reduced after high-frequency rTMS treatment than in the control group; the aspiration degree was significantly increased after high-frequency rTMS treatment than in the control group; the levels of glutamate and dopamine were significantly increased after high-frequency rTMS treatment than in the control group; Moreover, the Kubota’s water-swallowing test scores were significantly reduced after high-frequency rTMS treatment than after low-frequency rTMS treatment; the levels of glutamate and dopamine were significantly increased after high-frequency rTMS treatment than after low-frequency rTMS treatment. Conclusions High-frequency rTMS was effective for swallowing disorders, which may be related to increased levels of intracranial glutamate and dopamine.

Effectiveness of Low-Frequency rTMS and Intensive Speech Therapy in Poststroke Patients with Aphasia: A Pilot Study Based on Evaluation by fMRI in Relation to Type of Aphasia

2012 ◽  
Vol 68 (4) ◽  
pp. 199-208 ◽  
Author(s):  
Masahiro Abo ◽  
Wataru Kakuda ◽  
Motoi Watanabe ◽  
Azusa Morooka ◽  
Katsuya Kawakami ◽  
...  
Keyword(s):  
Pilot Study ◽  
Speech Therapy ◽  
Low Frequency ◽  
Low Frequency Rtms
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