scholarly journals Co-optimization Learning Network for MRI Segmentation of Ischemic Penumbra Tissues

2021 ◽  
Vol 15 ◽  
Author(s):  
Liangliang Liu ◽  
Jing Zhang ◽  
Jin-xiang Wang ◽  
Shufeng Xiong ◽  
Hui Zhang

Convolutional neural networks (CNNs) have brought hope for the medical image auxiliary diagnosis. However, the shortfall of labeled medical image data is the bottleneck that limits the performance improvement of supervised CNN methods. In addition, annotating a large number of labeled medical image data is often expensive and time-consuming. In this study, we propose a co-optimization learning network (COL-Net) for Magnetic Resonance Imaging (MRI) segmentation of ischemic penumbra tissues. COL-Net base on the limited labeled samples and consists of an unsupervised reconstruction network (R), a supervised segmentation network (S), and a transfer block (T). The reconstruction network extracts the robust features from reconstructing pseudo unlabeled samples, which is the auxiliary branch of the segmentation network. The segmentation network is used to segment the target lesions under the limited labeled samples and the auxiliary of the reconstruction network. The transfer block is used to co-optimization the feature maps between the bottlenecks of the reconstruction network and segmentation network. We propose a mix loss function to optimize COL-Net. COL-Net is verified on the public ischemic penumbra segmentation challenge (SPES) with two dozen labeled samples. Results demonstrate that COL-Net has high predictive accuracy and generalization with the Dice coefficient of 0.79. The extended experiment also shows COL-Net outperforms most supervised segmentation methods. COL-Net is a meaningful attempt to alleviate the limited labeled sample problem in medical image segmentation.

Author(s):  
Hong Shen

In this chapter, we will give an intuitive introduction to the general problem of 3D medical image segmentation. We will give an overview of the popular and relevant methods that may be applicable, with a discussion about their advantages and limits. Specifically, we will discuss the issue of incorporating prior knowledge into the segmentation of anatomic structures and describe in detail the concept and issues of knowledge-based segmentation. Typical sample applications will accompany the discussions throughout this chapter. We hope this will help an application developer to improve insights in the understanding and application of various computer vision approaches to solve real-world problems of medical image segmentation.


2011 ◽  
pp. 1144-1161
Author(s):  
Hong Shen

In this chapter, we will give an intuitive introduction to the general problem of 3D medical image segmentation. We will give an overview of the popular and relevant methods that may be applicable, with a discussion about their advantages and limits. Specifically, we will discuss the issue of incorporating prior knowledge into the segmentation of anatomic structures and describe in detail the concept and issues of knowledge-based segmentation. Typical sample applications will accompany the discussions throughout this chapter. We hope this will help an application developer to improve insights in the understanding and application of various computer vision approaches to solve real-world problems of medical image segmentation.


Author(s):  
Hong Shen

In this chapter, we will give an intuitive introduction to the general problem of 3D medical image segmentation. We will give an overview of the popular and relevant methods that may be applicable, with a discussion about their advantages and limits. Specifically, we will discuss the issue of incorporating prior knowledge into the segmentation of anatomic structures and describe in detail the concept and issues of knowledge-based segmentation. Typical sample applications will accompany the discussions throughout this chapter. We hope this will help an application developer to improve insights in the understanding and application of various computer vision approaches to solve real-world problems of medical image segmentation.


Electronics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 348
Author(s):  
Choongsang Cho ◽  
Young Han Lee ◽  
Jongyoul Park ◽  
Sangkeun Lee

Semantic image segmentation has a wide range of applications. When it comes to medical image segmentation, its accuracy is even more important than those of other areas because the performance gives useful information directly applicable to disease diagnosis, surgical planning, and history monitoring. The state-of-the-art models in medical image segmentation are variants of encoder-decoder architecture, which is called U-Net. To effectively reflect the spatial features in feature maps in encoder-decoder architecture, we propose a spatially adaptive weighting scheme for medical image segmentation. Specifically, the spatial feature is estimated from the feature maps, and the learned weighting parameters are obtained from the computed map, since segmentation results are predicted from the feature map through a convolutional layer. Especially in the proposed networks, the convolutional block for extracting the feature map is replaced with the widely used convolutional frameworks: VGG, ResNet, and Bottleneck Resent structures. In addition, a bilinear up-sampling method replaces the up-convolutional layer to increase the resolution of the feature map. For the performance evaluation of the proposed architecture, we used three data sets covering different medical imaging modalities. Experimental results show that the network with the proposed self-spatial adaptive weighting block based on the ResNet framework gave the highest IoU and DICE scores in the three tasks compared to other methods. In particular, the segmentation network combining the proposed self-spatially adaptive block and ResNet framework recorded the highest 3.01% and 2.89% improvements in IoU and DICE scores, respectively, in the Nerve data set. Therefore, we believe that the proposed scheme can be a useful tool for image segmentation tasks based on the encoder-decoder architecture.


Author(s):  
Zhenzhen Yang ◽  
Pengfei Xu ◽  
Yongpeng Yang ◽  
Bing-Kun Bao

The U-Net has become the most popular structure in medical image segmentation in recent years. Although its performance for medical image segmentation is outstanding, a large number of experiments demonstrate that the classical U-Net network architecture seems to be insufficient when the size of segmentation targets changes and the imbalance happens between target and background in different forms of segmentation. To improve the U-Net network architecture, we develop a new architecture named densely connected U-Net (DenseUNet) network in this article. The proposed DenseUNet network adopts a dense block to improve the feature extraction capability and employs a multi-feature fuse block fusing feature maps of different levels to increase the accuracy of feature extraction. In addition, in view of the advantages of the cross entropy and the dice loss functions, a new loss function for the DenseUNet network is proposed to deal with the imbalance between target and background. Finally, we test the proposed DenseUNet network and compared it with the multi-resolutional U-Net (MultiResUNet) and the classic U-Net networks on three different datasets. The experimental results show that the DenseUNet network has significantly performances compared with the MultiResUNet and the classic U-Net networks.


Ideally, secure transmission of medical image data is one of the major challenges in health sector. The National Health Information Network has to protect the data in confidential manner. Storage is also one of the basic concern along with secure transmission. In this paper we propose an algorithm that supports confidentiality, authentication and integrity implementation of the scrambled data before transmitting on the communication medium. Before communication the data is compressed while keeping data encrypted. The research work demonstrate with simulation results. The results shows that the proposed work effectively maintains confidentiality, authentication and integrity. The experimental results evaluated medical image quality like PSNR, MSE, SC, and NAEetc.


Author(s):  
Lars J. Isaksson ◽  
Paul Summers ◽  
Sara Raimondi ◽  
Sara Gandini ◽  
Abhir Bhalerao ◽  
...  

Abstract Researchers address the generalization problem of deep image processing networks mainly through extensive use of data augmentation techniques such as random flips, rotations, and deformations. A data augmentation technique called mixup, which constructs virtual training samples from convex combinations of inputs, was recently proposed for deep classification networks. The algorithm contributed to increased performance on classification in a variety of datasets, but so far has not been evaluated for image segmentation tasks. In this paper, we tested whether the mixup algorithm can improve the generalization performance of deep segmentation networks for medical image data. We trained a standard U-net architecture to segment the prostate in 100 T2-weighted 3D magnetic resonance images from prostate cancer patients, and compared the results with and without mixup in terms of Dice similarity coefficient and mean surface distance from a reference segmentation made by an experienced radiologist. Our results suggest that mixup offers a statistically significant boost in performance compared to non-mixup training, leading to up to 1.9% increase in Dice and a 10.9% decrease in surface distance. The mixup algorithm may thus offer an important aid for medical image segmentation applications, which are typically limited by severe data scarcity.


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