scholarly journals Imaginary Worlds and Their Borders: An Opinion Article

2021 ◽  
Vol 12 ◽  
Author(s):  
Axel Wiepke ◽  
Alex Miklashevsky
Keyword(s):  
Opinion Article

Response to the “In my opinion article”

2000 ◽  
Vol 64 (10) ◽  
pp. 692-693
Author(s):  
LS Behar-Horenstein ◽  
TA Dolan ◽  
GS Mitchell ◽  
FJ Courts
Keyword(s):  
Opinion Article

Translating Principles of Speech Science to Clinical Practice: Current and Future Trends in Craniofacial Disorders

2008 ◽  
Vol 18 (1) ◽  
pp. 31-40 ◽  
Author(s):  
David J. Zajac
Keyword(s):  
Clinical Practice ◽  
Speech Intelligibility ◽  
Current Practice ◽  
Computer Assisted ◽  
Behavioral Management ◽  
Single Word ◽  
Future Directions ◽  
Speech Science ◽  
The Impact ◽  
Opinion Article

Abstract The purpose of this opinion article is to review the impact of the principles and technology of speech science on clinical practice in the area of craniofacial disorders. Current practice relative to (a) speech aerodynamic assessment, (b) computer-assisted single-word speech intelligibility testing, and (c) behavioral management of hypernasal resonance are reviewed. Future directions and/or refinement of each area are also identified. It is suggested that both challenging and rewarding times are in store for clinical researchers in craniofacial disorders.

Opinion Article

2017 ◽  
Vol 1 (1) ◽  
Author(s):  
Seher Kaşli
Keyword(s):  
Opinion Article

scholarly journals It’s Time to Change Direction on Agility Research: a Call to Action

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Warren Young ◽  
Russell Rayner ◽  
Scott Talpey
Keyword(s):  
Ecological Validity ◽  
Primary Outcome Measure ◽  
Future Research ◽  
Call To Action ◽  
Change Of Direction ◽  
Movement Component ◽  
Research Questions ◽  
Action Coupling ◽  
Perception Action ◽  
Opinion Article

AbstractAgility is an important skill for both attackers and defenders in invasion sports such as codes of football. On the sporting field, agility requires reacting to a stimulus, often presented by an opponent’s movement, before a change of direction or speed. There is a plethora of research that examines the movement component of agility in isolation, which is described as change-of-direction (COD) ability, and this is thought to underpin agility performance. This opinion article proposes that COD ability should not be researched as the only or primary outcome measure when the objective is to inform agility performance in invasion sports. It is argued that pre-planned COD movements and tests lack ecological validity because they lack perception-action coupling and involve movement out of context from the game. The movement techniques and strength qualities required for the performance of COD tests can be quite different to those required for agility. It is suggested that COD tests can be applied to sports that involve pre-planned COD movements, but researchers should endeavour to use agility tests when studying invasion sports. Some new methods for assessing one-on-one agility contests are reported as potentially valuable for future research, and examples of research questions are provided.

scholarly journals What is medicinal chemistry? – Demystifying a rapidly evolving discipline!

MedChemComm ◽  
2017 ◽  
Vol 8 (9) ◽  
pp. 1739-1741 ◽  
Author(s):  
Selina Y. L. Holbrook ◽  
Sylvie Garneau-Tsodikova
Keyword(s):  
Graduate Students ◽  
Medicinal Chemistry ◽  
Opinion Article

Opinion article summarizing answers to this broad and controversial question obtained from over 60 people from “all walks of life”, including people from academia and industry, ranging from graduate students to established researchers and professors.

scholarly journals Estrogen as Jekyll and Hyde: regulation of cell death

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 161 ◽  
Author(s):  
Wen Zhou ◽  
Xiaoxia Zhu
Keyword(s):  
Breast Cancer ◽  
Cell Death ◽  
Breast Cancer Cells ◽  
Breast Cancer Patients ◽  
Physiological Level ◽  
Cancer Cell Death ◽  
Er Positive ◽  
Nfκb Pathway ◽  
Opinion Article ◽  
Positive Breast Cancer

Sustained estrogenic exposure increases the risk and/or the progression of various cancers, including those of the breast, endometrium and ovary. Unexpectedly, physiological level of estrogen together with a novel IKKα inhibitor BAY11-7082 could effectively induce cell apoptosis in ER-positive breast cancer cells, suggesting combining estrogen with IKKα inhibition may be beneficial for breast cancer patients. This opinion article touches upon the dual role estrogen played in inducing cancer cell death and asks whether use of estrogen in combination with IKKα-targeted therapy would be possible reconsider the newly identified crosstalk between ER and NFκB pathway which can be utilized to switch the effects of estrogen on cell death.

scholarly journals Vaccination against human papilloma virus in the light of quaternary prevention

2019 ◽  
Vol 14 (41) ◽  
pp. 1800 ◽  
Author(s):  
Miguel Pizzanelli ◽  
Marc Jamoulle
Keyword(s):  
Cervical Cancer ◽  
Hpv Vaccine ◽  
Pharmaceutical Companies ◽  
Papilloma Virus ◽  
Family Doctors ◽  
Multiple Dimensions ◽  
The World ◽  
World Organization ◽  
Quaternary Prevention ◽  
Opinion Article

In spite of the demonstrated benefits, the question of HPV massive vaccination is still subject to intense discussions and controversies. The protection against cancer is still unproven and need more time to be accurate about the quantification of the decrease in cervical cancer. The analysis of HPV vaccine relevance is very complex due to several overlapped levels to be considered. The authors analyze many of the ethical, sociological, economic, political and finally scientific issues involved. The population trust in vaccines has been affected owing to dubious practices of many pharmaceutical companies. Faced with this manipulation of information on a worldwide scale, general practitioners have organized themselves to fight this uncertainty. Quaternary prevention, a concept supported by the World Organization of Family doctors, advocates the application of ethically acceptable procedures in health care. This opinion article addresses some of the multiple dimensions involved to encourage reflection on this issue.

Systemic Lupus Erythematosus-An Opinion Article

2015 ◽  
Vol 05 (04) ◽  
Author(s):  
Maria Jose MorenoMartinez ◽  
Manuel Jose Moreno Ramos
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Opinion Article

Individualized metabolomics: opportunities and challenges

2020 ◽  
Vol 58 (6) ◽  
pp. 939-947
Author(s):  
Biswapriya Misra
Keyword(s):  
Health Care ◽  
Precision Medicine ◽  
Metabolic Regulation ◽  
Personal Space ◽  
High Quality ◽  
Omics Technologies ◽  
Disease Phenotypes ◽  
Targeted Treatments ◽  
Monitoring Devices ◽  
Opinion Article

AbstractThe goal of advancing science in health care is to provide high quality treatment and therapeutic opportunities to patients in need. This is especially true in precision medicine, wherein the ultimate goal is to link disease phenotypes to targeted treatments and novel therapeutics at the scale of an individual. With the advent of -omics technologies, such as genomics, proteomics, microbiome, among others, the metabolome is of wider and immediate interest for its important role in metabolic regulation. The metabolome, of course, comes with its own questions regarding technological challenges. In this opinion article, I attempt to interrogate some of the main challenges associated with individualized metabolomics, and available opportunities in the context of its clinical application. Some questions this article addresses and attempts to find answers for are: Can a personal metabolome (n = 1) be inexpensive, affordable and informative enough (i.e. provide predictive yet validated biomarkers) to represent the entirety of a population? How can a personal metabolome complement advances in other -omics areas and the use of monitoring devices, which occupy our personal space?

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