scholarly journals The Psychology of Food Cravings in Patients With First-Episode Psychosis

2020 ◽  
Vol 11 ◽  
Author(s):  
Young-Hyuk Kim ◽  
Seunghyong Ryu ◽  
Hee-Jung Nam ◽  
Mina Kim ◽  
Min Jhon ◽  
...  
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Perceived Stress ◽  
First Episode Psychosis ◽  
Psychological Characteristics ◽  
First Episode ◽  
Loss Of Control ◽  
Food Cravings ◽  
Significant Weight Gain ◽  
Episode Psychosis

Objectives: Food cravings may cause weight gain in patients with schizophrenia. This study investigated psychological characteristics associated with food cravings in patients with first-episode psychosis.Methods: This study analyzed data from a clinical cohort of first-episode psychosis patients taking antipsychotics for 3 months or less. The strength of food cravings was measured using the General Food Cravings Questionnaire-Trait (G-FCQ-T). Psychological characteristics and psychiatric symptoms were investigated with the Positive and Negative Symptom Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), Social and Occupational Functioning Assessment Scale, Rosenberg Self-Esteem Scale (RSES), and Perceived Stress Scale (PSS). Clinical characteristics were compared according to significant weight gain (≥10% increase in body weight compared to baseline) over 3 months. Associations between the G-FCQ-T and other psychiatric scales were investigated. We conducted sex-stratified analyses.Results: In total, 182 patients (78 males and 104 females) with first-episode psychosis were enrolled in this study. In females, the G-FCQ-T total score at baseline was associated with baseline body weight and significant weight gain over 3 months. The PSS scales were significantly associated the G-FCQ-T total and all subscale scores in female participants. Scores on the RSES and CDSS were significantly associated with the G-FCQ-T total score and with the preoccupation and loss of control subscale scores. The PANSS negative and general subscales were significantly associated with the positive outcome expectancy and loss of control subscales of the G-FCQ-T, respectively. In males, the only significant association was between the loss of control subscale and RSES scores. Linear regression analysis showed significant associations of PSS scores with the total and all subscale scores of the G-FCQ-T despite the loss of significance for other variables.Conclusion: These results indicate that the food cravings in patients with first-episode psychosis, which were associated with weight gain, were influenced by perceived stress in females. To reduce food cravings in female patients with schizophrenia, interventions aimed at perceived stress should be considered.

Effect of Treatment on Weight Gain and Metabolic Abnormalities in Patients with First-Episode Psychosis

2009 ◽  
Vol 43 (9) ◽  
pp. 812-817 ◽  
Author(s):  
Swapna Verma ◽  
Alvin Liew ◽  
Mythily Subramaniam ◽  
Lye Yin Poon
Keyword(s):  
Weight Gain ◽  
Density Lipoprotein ◽  
Female Gender ◽  
Serum Levels ◽  
First Episode Psychosis ◽  
First Episode ◽  
Intervention Programme ◽  
Significant Weight Gain ◽  
Episode Psychosis ◽  
Clinically Significant

Objective: The aim of the present prospective and naturalistic study was to examine the effects of antipsychotic medication on weight and serum levels of lipids, glucose and insulin in first-episode psychosis patients. Method: Fifty-six patients admitted to the Singapore Early Psychosis Intervention Programme participated in this study. They were assessed at baseline (i.e. within 72 h of starting antipsychotics), and 6 months later. Weight (kg) and height (m) were measured and body mass index (BMI) was calculated. Blood samples were taken after a 12 h overnight fast. Choice of antipsychotics was based on the treating physician's clinical decision. Total cumulative Chlorpromazine (CPZ) equivalent of antipsychotic exposure during the 6 months was calculated. Statistical analyses were carried out for comparisons between baseline and 6 months, and for the two outcome event groups of ≥7% versus <7% weight gain. Where appropriate, confounders were controlled. Results and conclusion: There were significant increases in BMI, serum levels of triglyceride, low-density lipoprotein and total cholesterol from baseline to 6 months. Mean increase in weight was 6.2±7.0 kg (p < 0.05) and 65% of the patients had clinically significant weight gain (i.e. ≥7% increase from baseline). On logistic regression lower baseline BMI, female gender, and younger age, were associated with clinically significant weight gain.

scholarly journals S232. ASSOCIATIONS OF FOOD CRAVING WITH PSYCHOLOGICAL AND PHYSICAL CHARACTERISTICS IN PATIENTS WITH FIRST-EPISODE PSYCHOSIS

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S127-S127
Author(s):  
Yeonghyeok Kim ◽  
Seunghyong Ryu ◽  
Ju-Yeon Lee ◽  
Young-Chul Chung ◽  
Sung-Wan Kim
Keyword(s):  
Weight Gain ◽  
Perceived Stress ◽  
Self Esteem ◽  
First Episode Psychosis ◽  
First Episode ◽  
Food Craving ◽  
Obsessive Compulsive ◽  
T Score ◽  
Episode Psychosis ◽  
Male Patients

Abstract Background Obesity in patients with schizophrenia have important effects on metabolic syndrome, cardiovascular disease, mortality, quality of life and treatment compliance. There is a growing interest in recognizing and intervening this problem. In this study, we aimed to explore the associations of food craving and eating pattern on weight gain and psychiatric characteristics in patients with first-episode psychosis. Methods We analyzed data from clinical cohort of first-episode psychosis. To exclude compounding effects of antipsychotics, we included patients who took one of amisulpride, paliperidone, and aripiprazole and whose duration of treatment was 3 months or less. The degree of food craving was measured by General Food Craving Questionnaire-Trait (G-FCQ-T). Psychiatric characteristics were investigated by Positive and Negative Syndrome Scale, Yale-Brown Obsessive Compulsive Scale (YBOCS), Beck Depression Inventory (BDI), Rosenberg Self-Esteem Scale (SES), and Perceived Stress Scale (PSS). Weight was measured at baseline and 3 months. Associations between the G-FCQ-T and other measures including weight gain for 3 months were analyzed by gender. Results A total of 180 patients with first-episode psychosis were enrolled in this analysis. In male patients, the G-FCQ-T score was significantly associated with scores on the YBOCS and SES. In female patients, the G-FCQ-T score was significantly associated with the BDI, PSS, baseline body weight and weight gain for 3 months Discussion This study demonstrated the associations of food craving with depression, perceived stress, and weight gain in female patients and with obsessive compulsive symptoms and self-esteem in male patients. These results suggest various moderators impact weight gain and food craving in patients with first-episode psychosis.

scholarly journals Circulating lipids associate with future weight gain in individuals with an at-risk mental state and in first-episode psychosis

2020 ◽  
Author(s):  
Santosh Lamichhane ◽  
Alex M. Dickens ◽  
Partho Sen ◽  
Heikki Laurikainen ◽  
Jaana Suvisaari ◽  
...  
Keyword(s):  
At Risk ◽  
Weight Gain ◽  
High Risk ◽  
Psychotic Disorders ◽  
First Episode Psychosis ◽  
Molecular Signature ◽  
First Episode ◽  
Baseline Serum ◽  
Average Life Span ◽  
Episode Psychosis

AbstractPatients with schizophrenia have a lower than average life span, largely due to the increased prevalence of cardiometabolic co-morbidities. Identification of individuals with psychotic disorders with a high risk of rapid weight gain, and the associated development of metabolic complications, is an unmet need as regards public health. Here, we applied mass spectrometry-based lipidomics in a prospective study comprising 48 controls (CTR), 44 first-episode psychosis (FEP) patients and 22 individuals at clinical-high-risk (CHR) for psychosis, from two study centers (Turku/Finland and London/UK). Baseline serum samples were analyzed by lipidomics, while body mass index (BMI) was assessed at baseline and after 12 months. We found that baseline triacylglycerols with low double bond counts and carbon numbers were positively associated with the change in BMI at follow-up. In addition, a molecular signature comprised of two triacylglycerols (TG(48:0) and TG(45:0)), was predictive of weight gain in individuals with a psychotic disorder, with an area under the receiver operating characteristic curve (AUROC) of 0.74 (95% CI: 0.60–0.85). When independently tested in the CHR group, this molecular signature predicted said weight change with AUROC = 0.73 (95% CI: 0.61–0.83). We conclude that molecular lipids may serve as a predictor of weight gain in psychotic disorders in at-risk individuals, and may thus provide a useful marker for identifying individuals who are most prone to developing cardiometabolic co-morbidities.

scholarly journals Does food responsiveness change in people with first episode psychosis (FEP) over a period of 6 months after commencing antipsychotics? Preliminary results

BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S255-S255
Author(s):  
Adrian Heald ◽  
Mark Shakespeare ◽  
Kevin Williamson ◽  
Adrianne Close ◽  
Adrian Phillipson ◽  
...  
Keyword(s):  
Rating Scales ◽  
Eating Behaviour ◽  
First Episode Psychosis ◽  
Intuitive Eating ◽  
First Episode ◽  
Antipsychotic Treatment ◽  
Loss Of Control ◽  
Convenience Sample ◽  
Preliminary Results ◽  
Episode Psychosis

AimsWe here present preliminary results from our study to understand better the changes in people’ s experience of food in the months after diagnosis with first episode psychosis (FEP). Weight gain often occurs in the weeks/months after diagnosis and is related to an increase in appetite and food intake. Many drugs that are effective in treating psychosis are associated with changes in the way that people experience reward when they eat.The aim of this project is to increase our understanding of exactly why this happens in terms of an individual's experience of food reward and reduced satiety – and therefore how we can help people with FEP to keep their weight down. At this stage we are looking at the feasibility of applying currently available evaluation tools to people in this situation.MethodA convenience sample was used to recruit 10 service users from RDaSH NHS FT Early Intervention Services. This is a feasibility study which will provide data to underpin a fully powered, larger trial.Rating scales applied were:Power of food questionnaire: measures responsiveness to the food environment.Intuitive Eating Scale: measures an individual's tendency to follow their physical hunger and satiety cues.The loss of control over eating scale (LOCES): measures a global sense of whether individuals experience LOC over eating.Dutch Eating Behaviour Questionnaire (DEBQ): measures restrained eating, emotional eating and external eating.ResultThe ages of the participants ranged from 17-26 years. All were started on Olanzapine at the dose of 5 or 10 mg daily.Baseline total scores for the Power of Food (2.47-3.80)/5 (higher score = more responsiveness) and Intuitive Eating scales (2.10-2.62)/5 (higher score = greater tendency to follow hunger and satiety cues) were in the mid-range, while the LOCES scores varied widely from 1.50-2.38/5.The DEBQ restrained subscale score range was 2.40-2.80/5 (higher indicates greater restraint with food) while the DEBQ external subscale ranged from 2.70—3.00/5 (higher = greater tendency to overeat) and the DEBQ emotional subtotal score was 1.92-1.94/5, in keeping with a relatively low emotional drive to eat.ConclusionOur preliminary results reveal at the beginning of antipsychotic treatment a moderate responsiveness to food and tendency to follow hunger/ satiety cues, with scores for Loss of Control of eating in the low to moderate range and a low emotional drive to eat. The difference between these and the follow-up eating behaviour scores will provide important clues as to the precise changes in eating behaviour with anti-psychotic treatment in FEP.

Perceived stress, social functioning and quality of life in first‐episode psychosis: A 1‐year follow‐up study

2020 ◽  
Author(s):  
Laura Ortega ◽  
Itziar Montalvo ◽  
Rosa Monseny ◽  
Maria Dolors Burjales‐Martí ◽  
Lourdes Martorell ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Social Functioning ◽  
Perceived Stress ◽  
First Episode Psychosis ◽  
First Episode ◽  
Follow Up Study ◽  
Episode Psychosis

Clinical correlates of weight gain in first episode psychosis patients treated with olanzapine

2003 ◽  
Vol 60 (1) ◽  
pp. 372 ◽  
Author(s):  
R. Zipursky ◽  
H. Gu ◽  
A.I. Green ◽  
F. Centorrina ◽  
I. Glick ◽  
...  
Keyword(s):  
Weight Gain ◽  
First Episode Psychosis ◽  
First Episode ◽  
Clinical Correlates ◽  
Episode Psychosis

Are symptoms associated with increased levels of perceived stress in first-episode psychosis?

2009 ◽  
Vol 18 (3) ◽  
pp. 186-194 ◽  
Author(s):  
Laoise Renwick ◽  
Deirdre Jackson ◽  
Niall Turner ◽  
Marie Sutton ◽  
Sharon Foley ◽  
...  
Keyword(s):  
Perceived Stress ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis

scholarly journals Association Between Circulating Lipids and Future Weight Gain in Individuals With an At-Risk Mental State and in First-Episode Psychosis

2020 ◽  
Author(s):  
Santosh Lamichhane ◽  
Alex M Dickens ◽  
Partho Sen ◽  
Heikki Laurikainen ◽  
Faith Borgan ◽  
...  
Keyword(s):  
At Risk ◽  
Weight Gain ◽  
High Risk ◽  
Psychotic Disorders ◽  
First Episode Psychosis ◽  
Molecular Signature ◽  
First Episode ◽  
Baseline Serum ◽  
Average Life Span ◽  
Episode Psychosis

Abstract Patients with schizophrenia have a lower than average life span, largely due to the increased prevalence of cardiometabolic comorbidities. There is an unmet public health need to identify individuals with psychotic disorders who have a high risk of rapid weight gain and who are at risk of developing metabolic complications. Here, we applied mass spectrometry-based lipidomics in a prospective study comprising 48 healthy controls (CTR), 44 first-episode psychosis (FEP) patients, and 22 individuals at clinical high risk (CHR) for psychosis, from 2 study centers (Turku, Finland and London, UK). Baseline serum samples were analyzed using lipidomics, and body mass index (BMI) was assessed at baseline and after 12 months. We found that baseline triacylglycerols (TGs) with low double-bond counts and carbon numbers were positively associated with the change in BMI at follow-up. In addition, a molecular signature comprised of 2 TGs (TG[48:0] and TG[45:0]) was predictive of weight gain in individuals with a psychotic disorder, with an area under the receiver operating characteristic curve (AUROC) of 0.74 (95% CI: 0.60–0.85). When independently tested in the CHR group, this molecular signature predicted said weight change with AUROC = 0.73 (95% CI: 0.61–0.83). We conclude that molecular lipids may serve as a predictor of weight gain in psychotic disorders in at-risk individuals and may thus provide a useful marker for identifying individuals who are most prone to developing cardiometabolic comorbidities.

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